# OC Root 2nd 3rd 4th 5th PC Gene/Definition OC.635045 Eukaryotes.775636 Protists.110608 Alveolates.57215 - smin.16914 smin:v1.2.010150.t1 symbB.v1.2.010150.t1; - OC.635046 Archaea.99412 - - - loki.1235 loki:Lokiarch_00630 abfD_1; 4-hydroxybutyryl-CoA dehydratase/vinylacetyl-CoA-Delta-isomerase; K14534 4-hydroxybutyryl-CoA dehydratase / vinylacetyl-CoA-Delta-isomerase [EC:4.2.1.120 5.3.3.3] OC.635047 Archaea.100385 - - - loki.2434 loki:Lokiarch_26350 abfD_2; 4-hydroxybutyryl-CoA dehydratase/vinylacetyl-CoA-Delta-isomerase; K14534 4-hydroxybutyryl-CoA dehydratase / vinylacetyl-CoA-Delta-isomerase [EC:4.2.1.120 5.3.3.3] OC.635048 Archaea.9702 Crenarchaeota.262 Ignicoccus.829 - iho.589 iho:Igni_0595 Vinylacetyl-CoA Delta-isomerase; K14534 4-hydroxybutyryl-CoA dehydratase / vinylacetyl-CoA-Delta-isomerase [EC:4.2.1.120 5.3.3.3] OC.635048 Archaea.9702 Crenarchaeota.262 Ignicoccus.829 - iis.103 iis:EYM_00450 4-hydroxybutyryl-CoA dehydratase; K14534 4-hydroxybutyryl-CoA dehydratase / vinylacetyl-CoA-Delta-isomerase [EC:4.2.1.120 5.3.3.3] OC.635048 Archaea.9702 Crenarchaeota.262 - - pfm.1224 pfm:Pyrfu_1275 Vinylacetyl-CoA Delta-isomerase; K14534 4-hydroxybutyryl-CoA dehydratase / vinylacetyl-CoA-Delta-isomerase [EC:4.2.1.120 5.3.3.3] OC.635048 Archaea.9702 Crenarchaeota.262 - - sto.1772 sto:STK_16590 4-hydroxybutyryl-CoA dehydratase; K14534 4-hydroxybutyryl-CoA dehydratase / vinylacetyl-CoA-Delta-isomerase [EC:4.2.1.120 5.3.3.3] OC.635048 Archaea.9702 Crenarchaeota.262 Sulfolobus.186 Sulfolobus_acidocaldarius.1164 sai.2006 sai:Saci_2143 abfD; gamma-aminobutyrate metabolism dehydratase/isomerase; K14534 4-hydroxybutyryl-CoA dehydratase / vinylacetyl-CoA-Delta-isomerase [EC:4.2.1.120 5.3.3.3] OC.635048 Archaea.9702 Crenarchaeota.262 Sulfolobus.186 Sulfolobus_acidocaldarius.1164 sacn.2055 sacn:SacN8_10430 gamma-aminobutyrate metabolism dehydratase/isomerase; K14534 4-hydroxybutyryl-CoA dehydratase / vinylacetyl-CoA-Delta-isomerase [EC:4.2.1.120 5.3.3.3] OC.635048 Archaea.9702 Crenarchaeota.262 Sulfolobus.186 Sulfolobus_acidocaldarius.1164 sacr.2097 sacr:SacRon12I_10685 gamma-aminobutyrate metabolism dehydratase/isomerase; K14534 4-hydroxybutyryl-CoA dehydratase / vinylacetyl-CoA-Delta-isomerase [EC:4.2.1.120 5.3.3.3] OC.635048 Archaea.9702 Crenarchaeota.262 Sulfolobus.186 Sulfolobus_acidocaldarius.1164 sacs.1867 sacs:SUSAZ_09780 4-hydroxybutyryl-CoA dehydratase; K14534 4-hydroxybutyryl-CoA dehydratase / vinylacetyl-CoA-Delta-isomerase [EC:4.2.1.120 5.3.3.3] OC.635048 Archaea.9702 Crenarchaeota.262 Sulfolobus.2852 Sulfolobus_solfataricus.1948 sso.2299 sso:SSO2738 abfD-2; 4-hydroxybutyryl-CoA dehydratase (abfD-2); K14534 4-hydroxybutyryl-CoA dehydratase / vinylacetyl-CoA-Delta-isomerase [EC:4.2.1.120 5.3.3.3] OC.635048 Archaea.9702 Crenarchaeota.262 Sulfolobus.2852 Sulfolobus_solfataricus.1948 sol.534 sol:Ssol_0550 Vinylacetyl-CoA Delta-isomerase; K14534 4-hydroxybutyryl-CoA dehydratase / vinylacetyl-CoA-Delta-isomerase [EC:4.2.1.120 5.3.3.3] OC.635048 Archaea.9702 Crenarchaeota.262 Sulfolobus.2852 Sulfolobus_solfataricus.1948 ssoa.529 ssoa:SULA_0541 4-hydroxybutyryl-CoA dehydratase; K14534 4-hydroxybutyryl-CoA dehydratase / vinylacetyl-CoA-Delta-isomerase [EC:4.2.1.120 5.3.3.3] OC.635048 Archaea.9702 Crenarchaeota.262 Sulfolobus.2852 Sulfolobus_solfataricus.1948 ssol.533 ssol:SULB_0543 4-hydroxybutyryl-CoA dehydratase; K14534 4-hydroxybutyryl-CoA dehydratase / vinylacetyl-CoA-Delta-isomerase [EC:4.2.1.120 5.3.3.3] OC.635048 Archaea.9702 Crenarchaeota.262 Sulfolobus.2852 Sulfolobus_solfataricus.1948 ssof.528 ssof:SULC_0541 4-hydroxybutyryl-CoA dehydratase; K14534 4-hydroxybutyryl-CoA dehydratase / vinylacetyl-CoA-Delta-isomerase [EC:4.2.1.120 5.3.3.3] OC.635048 Archaea.9702 Crenarchaeota.262 Sulfolobus.2852 Sulfolobus_islandicus.1626 sis.2455 sis:LS215_2744 Vinylacetyl-CoA Delta-isomerase; K14534 4-hydroxybutyryl-CoA dehydratase / vinylacetyl-CoA-Delta-isomerase [EC:4.2.1.120 5.3.3.3] OC.635048 Archaea.9702 Crenarchaeota.262 Sulfolobus.2852 Sulfolobus_islandicus.1626 sia.2342 sia:M1425_2585 Vinylacetyl-CoA Delta-isomerase; K14534 4-hydroxybutyryl-CoA dehydratase / vinylacetyl-CoA-Delta-isomerase [EC:4.2.1.120 5.3.3.3] OC.635048 Archaea.9702 Crenarchaeota.262 Sulfolobus.2852 Sulfolobus_islandicus.1626 sim.2392 sim:M1627_2638 Vinylacetyl-CoA Delta-isomerase; K14534 4-hydroxybutyryl-CoA dehydratase / vinylacetyl-CoA-Delta-isomerase [EC:4.2.1.120 5.3.3.3] OC.635048 Archaea.9702 Crenarchaeota.262 Sulfolobus.2852 Sulfolobus_islandicus.1626 sid.2473 sid:M164_2569 Vinylacetyl-CoA Delta-isomerase; K14534 4-hydroxybutyryl-CoA dehydratase / vinylacetyl-CoA-Delta-isomerase [EC:4.2.1.120 5.3.3.3] OC.635048 Archaea.9702 Crenarchaeota.262 Sulfolobus.2852 Sulfolobus_islandicus.1626 siy.2563 siy:YG5714_2751 Vinylacetyl-CoA Delta-isomerase; K14534 4-hydroxybutyryl-CoA dehydratase / vinylacetyl-CoA-Delta-isomerase [EC:4.2.1.120 5.3.3.3] OC.635048 Archaea.9702 Crenarchaeota.262 Sulfolobus.2852 Sulfolobus_islandicus.1626 sin.164 sin:YN1551_0139 Vinylacetyl-CoA Delta-isomerase; K14534 4-hydroxybutyryl-CoA dehydratase / vinylacetyl-CoA-Delta-isomerase [EC:4.2.1.120 5.3.3.3] OC.635048 Archaea.9702 Crenarchaeota.262 Sulfolobus.2852 Sulfolobus_islandicus.1626 sii.2648 sii:LD85_2896 Vinylacetyl-CoA Delta-isomerase; K14534 4-hydroxybutyryl-CoA dehydratase / vinylacetyl-CoA-Delta-isomerase [EC:4.2.1.120 5.3.3.3] OC.635048 Archaea.9702 Crenarchaeota.262 Sulfolobus.2852 Sulfolobus_islandicus.1626 sih.2472 sih:SiH_2522 Vinylacetyl-CoA Delta-isomerase; K14534 4-hydroxybutyryl-CoA dehydratase / vinylacetyl-CoA-Delta-isomerase [EC:4.2.1.120 5.3.3.3] OC.635048 Archaea.9702 Crenarchaeota.262 Sulfolobus.2852 Sulfolobus_islandicus.1626 sir.2286 sir:SiRe_2362 Vinylacetyl-CoA Delta-isomerase; K14534 4-hydroxybutyryl-CoA dehydratase / vinylacetyl-CoA-Delta-isomerase [EC:4.2.1.120 5.3.3.3] OC.635048 Archaea.9702 Crenarchaeota.262 Sulfolobus.2852 Sulfolobus_islandicus.1626 sic.2369 sic:SiL_2419 Aromatic ring hydroxylase; K14534 4-hydroxybutyryl-CoA dehydratase / vinylacetyl-CoA-Delta-isomerase [EC:4.2.1.120 5.3.3.3] OC.635048 Archaea.9702 Crenarchaeota.262 Sulfolobus.2852 - sula.2086 sula:BFU36_11260 4-hydroxybutyryl-CoA dehydratase; K14534 4-hydroxybutyryl-CoA dehydratase / vinylacetyl-CoA-Delta-isomerase [EC:4.2.1.120 5.3.3.3] OC.635048 Archaea.9702 Crenarchaeota.262 Metallosphaera.1663 - mse.1300 mse:Msed_1321 Vinylacetyl-CoA Delta-isomerase; K14534 4-hydroxybutyryl-CoA dehydratase / vinylacetyl-CoA-Delta-isomerase [EC:4.2.1.120 5.3.3.3] OC.635048 Archaea.9702 Crenarchaeota.262 Metallosphaera.1663 - mcn.886 mcn:Mcup_0888 4-hydroxybutyryl-CoA dehydratase; K14534 4-hydroxybutyryl-CoA dehydratase / vinylacetyl-CoA-Delta-isomerase [EC:4.2.1.120 5.3.3.3] OC.635048 Archaea.9702 Crenarchaeota.262 Metallosphaera.1663 - mhk.2151 mhk:DFR87_12060 4-hydroxybutyryl-CoA dehydratase; K14534 4-hydroxybutyryl-CoA dehydratase / vinylacetyl-CoA-Delta-isomerase [EC:4.2.1.120 5.3.3.3] OC.635048 Archaea.9702 Crenarchaeota.262 Acidianus.1093 - aho.1991 aho:Ahos_2036 4-hydroxybutyryl-CoA dehydratase; K14534 4-hydroxybutyryl-CoA dehydratase / vinylacetyl-CoA-Delta-isomerase [EC:4.2.1.120 5.3.3.3] OC.635048 Archaea.9702 Crenarchaeota.262 Acidianus.1093 - aman.331 aman:B6F84_01555 4-hydroxybutyryl-CoA dehydratase; K14534 4-hydroxybutyryl-CoA dehydratase / vinylacetyl-CoA-Delta-isomerase [EC:4.2.1.120 5.3.3.3] OC.635048 Archaea.9702 Crenarchaeota.262 Acidianus.1093 - abri.2195 abri:DFR85_12315 4-hydroxybutyryl-CoA dehydratase; K14534 4-hydroxybutyryl-CoA dehydratase / vinylacetyl-CoA-Delta-isomerase [EC:4.2.1.120 5.3.3.3] OC.635048 Archaea.9702 Crenarchaeota.262 Acidianus.1093 - asul.290 asul:DFR86_01545 4-hydroxybutyryl-CoA dehydratase; K14534 4-hydroxybutyryl-CoA dehydratase / vinylacetyl-CoA-Delta-isomerase [EC:4.2.1.120 5.3.3.3] OC.635048 Archaea.9702 Crenarchaeota.262 Pyrobaculum.975 - pai.1817 pai:PAE2693 4-hydroxyphenylacetate-3-hydroxylase, conjectural; K14534 4-hydroxybutyryl-CoA dehydratase / vinylacetyl-CoA-Delta-isomerase [EC:4.2.1.120 5.3.3.3] OC.635048 Archaea.9702 Crenarchaeota.262 Pyrobaculum.975 - pis.268 pis:Pisl_0248 Vinylacetyl-CoA delta-isomerase; K14534 4-hydroxybutyryl-CoA dehydratase / vinylacetyl-CoA-Delta-isomerase [EC:4.2.1.120 5.3.3.3] OC.635048 Archaea.9702 Crenarchaeota.262 Pyrobaculum.975 - pcl.1350 pcl:Pcal_1396 Vinylacetyl-CoA Delta-isomerase; K14534 4-hydroxybutyryl-CoA dehydratase / vinylacetyl-CoA-Delta-isomerase [EC:4.2.1.120 5.3.3.3] OC.635048 Archaea.9702 Crenarchaeota.262 Pyrobaculum.975 - pyr.712 pyr:P186_0718 Vinylacetyl-CoA delta-isomerase; K14534 4-hydroxybutyryl-CoA dehydratase / vinylacetyl-CoA-Delta-isomerase [EC:4.2.1.120 5.3.3.3] OC.635048 Archaea.9702 Crenarchaeota.262 Pyrobaculum.975 - tne.424 tne:Tneu_0422 Vinylacetyl-CoA Delta-isomerase; K14534 4-hydroxybutyryl-CoA dehydratase / vinylacetyl-CoA-Delta-isomerase [EC:4.2.1.120 5.3.3.3] OC.635048 Archaea.9702 Crenarchaeota.262 Pyrobaculum.975 - pyw.433 pyw:PYWP30_00440 4-hydroxybutyryl-CoA dehydratase; K14534 4-hydroxybutyryl-CoA dehydratase / vinylacetyl-CoA-Delta-isomerase [EC:4.2.1.120 5.3.3.3] OC.635048 Archaea.9702 Crenarchaeota.262 Pyrobaculum.976 - pog.1284 pog:Pogu_1298 Aromatic ring hydroxylase; K14534 4-hydroxybutyryl-CoA dehydratase / vinylacetyl-CoA-Delta-isomerase [EC:4.2.1.120 5.3.3.3] OC.635048 Archaea.9702 Crenarchaeota.262 Thermoproteus.1745 - ttn.1062 ttn:TTX_1102 4-hydroxybutyryl-CoA dehydratase; K14534 4-hydroxybutyryl-CoA dehydratase / vinylacetyl-CoA-Delta-isomerase [EC:4.2.1.120 5.3.3.3] OC.635048 Archaea.9702 Crenarchaeota.262 Thermoproteus.2340 - tuz.925 tuz:TUZN_0949 4-hydroxybutyryl-CoA dehydratase; K14534 4-hydroxybutyryl-CoA dehydratase / vinylacetyl-CoA-Delta-isomerase [EC:4.2.1.120 5.3.3.3] OC.635049 Eukaryotes.813273 Protists.178838 Stramenopiles.40622 - aaf.4218 aaf:AURANDRAFT_34356 hypothetical protein OC.635049 Archaea.36404 Thaumarchaeota.1615 Nitrosopumilus.2253 - nid.593 nid:NPIRD3C_0596 abfD; 4-hydroxybutyryl-CoA dehydratase; K14534 4-hydroxybutyryl-CoA dehydratase / vinylacetyl-CoA-Delta-isomerase [EC:4.2.1.120 5.3.3.3] OC.635049 Archaea.36404 Thaumarchaeota.1615 Nitrosopumilus.3297 - nin.1998 nin:NADRNF5_2050 abfD; 4-hydroxybutyryl-CoA dehydratase/vinylacetyl-CoA-Delta-isomerase; K14534 4-hydroxybutyryl-CoA dehydratase / vinylacetyl-CoA-Delta-isomerase [EC:4.2.1.120 5.3.3.3] OC.635049 Archaea.36404 Thaumarchaeota.1615 Nitrosopumilus.3408 - nir.178 nir:NSED_00835 vinylacetyl-CoA Delta-isomerase; K14534 4-hydroxybutyryl-CoA dehydratase / vinylacetyl-CoA-Delta-isomerase [EC:4.2.1.120 5.3.3.3] OC.635049 Archaea.36404 Thaumarchaeota.1615 Nitrosopumilus.4001 - nmr.213 nmr:Nmar_0207 Vinylacetyl-CoA Delta-isomerase; K14534 4-hydroxybutyryl-CoA dehydratase / vinylacetyl-CoA-Delta-isomerase [EC:4.2.1.120 5.3.3.3] OC.635049 Archaea.36404 Thaumarchaeota.1615 - - nkr.167 nkr:NKOR_00855 vinylacetyl-CoA Delta-isomerase; K14534 4-hydroxybutyryl-CoA dehydratase / vinylacetyl-CoA-Delta-isomerase [EC:4.2.1.120 5.3.3.3] OC.635049 Archaea.36404 Thaumarchaeota.1615 - - nct.1468 nct:NMSP_1505 hypothetical protein; K14534 4-hydroxybutyryl-CoA dehydratase / vinylacetyl-CoA-Delta-isomerase [EC:4.2.1.120 5.3.3.3] OC.635049 Archaea.36404 Thaumarchaeota.1615 - - csy.128 csy:CENSYa_0022 4-hydroxybutyryl-CoA dehydratase; K14534 4-hydroxybutyryl-CoA dehydratase / vinylacetyl-CoA-Delta-isomerase [EC:4.2.1.120 5.3.3.3] OC.635049 Archaea.36404 Thaumarchaeota.1615 Nitrososphaera.2228 - nga.3154 nga:Ngar_c34390 4-hydroxybutyryl-CoA dehydratase; K14534 4-hydroxybutyryl-CoA dehydratase / vinylacetyl-CoA-Delta-isomerase [EC:4.2.1.120 5.3.3.3] OC.635049 Archaea.36404 Thaumarchaeota.1615 Nitrososphaera.2228 - nvn.1677 nvn:NVIE_017160 4-hydroxybutyryl-CoA dehydratase; K14534 4-hydroxybutyryl-CoA dehydratase / vinylacetyl-CoA-Delta-isomerase [EC:4.2.1.120 5.3.3.3] OC.635049 Archaea.36404 Thaumarchaeota.1615 Nitrososphaera.2228 - nev.682 nev:NTE_00645 vinylacetyl-CoA delta-isomerase/4-hydroxybutyryl-CoA dehydratase; K14534 4-hydroxybutyryl-CoA dehydratase / vinylacetyl-CoA-Delta-isomerase [EC:4.2.1.120 5.3.3.3] OC.635049 Archaea.36404 Thaumarchaeota.1615 - - taa.2848 taa:NMY3_03315 abfD; 4-hydroxybutyryl-CoA dehydratase/vinylacetyl-CoA-Delta-isomerase; K14534 4-hydroxybutyryl-CoA dehydratase / vinylacetyl-CoA-Delta-isomerase [EC:4.2.1.120 5.3.3.3] OC.635049 Archaea.36404 Thaumarchaeota.1615 - - nbv.1198 nbv:T478_1248 abfD; gamma-aminobutyrate metabolism dehydratase/isomerase; K14534 4-hydroxybutyryl-CoA dehydratase / vinylacetyl-CoA-Delta-isomerase [EC:4.2.1.120 5.3.3.3] OC.635049 Archaea.36404 Thaumarchaeota.1615 - - tah.1382 tah:SU86_007675 4-hydroxybutyryl-CoA dehydratase; K14534 4-hydroxybutyryl-CoA dehydratase / vinylacetyl-CoA-Delta-isomerase [EC:4.2.1.120 5.3.3.3] OC.635049 Archaea.36404 Thaumarchaeota.1615 - - ndv.258 ndv:NDEV_0181 hcd; 4-hydroxybutyryl-CoA dehydratase/vinylacetyl-CoA-Delta-isomerase; K14534 4-hydroxybutyryl-CoA dehydratase / vinylacetyl-CoA-Delta-isomerase [EC:4.2.1.120 5.3.3.3] OC.635049 Archaea.95341 Thaumarchaeota.9421 - - ncv.157 ncv:NCAV_0127 4-hydroxybutyryl-CoA dehydratase; K14534 4-hydroxybutyryl-CoA dehydratase / vinylacetyl-CoA-Delta-isomerase [EC:4.2.1.120 5.3.3.3] OC.635050 Archaea.9975 Euryarchaeota.41817 Ferroplasma.1054 - fac.396 fac:FACI_IFERC01G0375 hypothetical protein OC.635050 Archaea.9975 Euryarchaeota.41817 Ferroplasma.1054 - fai.1208 fai:FAD_1294 hypothetical protein OC.635050 Archaea.9975 Crenarchaeota.3238 - - sto.111 sto:STK_00630 putative 4-hydroxybutyryl-CoA dehydratase OC.635050 Archaea.9975 Crenarchaeota.3238 Sulfolobus.2048 Sulfolobus_solfataricus.1728 sso.2106 sso:SSO2503 abfD-1; 4-hydroxybutyryl-CoA dehydratase (abfD-1) OC.635050 Archaea.9975 Crenarchaeota.3238 Sulfolobus.2048 Sulfolobus_solfataricus.1728 sol.325 sol:Ssol_0312 Vinylacetyl-CoA Delta-isomerase OC.635050 Archaea.9975 Crenarchaeota.3238 Sulfolobus.2048 Sulfolobus_solfataricus.1728 ssoa.322 ssoa:SULA_0305 4-hydroxybutyryl-CoA dehydratase OC.635050 Archaea.9975 Crenarchaeota.3238 Sulfolobus.2048 Sulfolobus_solfataricus.1728 ssol.326 ssol:SULB_0307 4-hydroxybutyryl-CoA dehydratase OC.635050 Archaea.9975 Crenarchaeota.3238 Sulfolobus.2048 Sulfolobus_solfataricus.1728 ssof.322 ssof:SULC_0305 4-hydroxybutyryl-CoA dehydratase OC.635050 Archaea.9975 Crenarchaeota.3238 Sulfolobus.2048 Sulfolobus_acidocaldarius.69 sai.1025 sai:Saci_1103 hydroxylase OC.635050 Archaea.9975 Crenarchaeota.3238 Sulfolobus.2048 Sulfolobus_acidocaldarius.69 sacn.1059 sacn:SacN8_05365 hydroxylase OC.635050 Archaea.9975 Crenarchaeota.3238 Sulfolobus.2048 Sulfolobus_acidocaldarius.69 sacr.1055 sacr:SacRon12I_05355 hydroxylase OC.635050 Archaea.9975 Crenarchaeota.3238 Sulfolobus.2048 Sulfolobus_acidocaldarius.69 sacs.982 sacs:SUSAZ_05145 4-hydroxybutyryl-CoA dehydratase OC.635050 Archaea.9975 Crenarchaeota.3238 Sulfolobus.2048 Sulfolobus_islandicus.1979 sis.342 sis:LS215_0322 Vinylacetyl-CoA Delta-isomerase OC.635050 Archaea.9975 Crenarchaeota.3238 Sulfolobus.2048 Sulfolobus_islandicus.1979 sia.303 sia:M1425_0293 Vinylacetyl-CoA Delta-isomerase OC.635050 Archaea.9975 Crenarchaeota.3238 Sulfolobus.2048 Sulfolobus_islandicus.1979 sim.302 sim:M1627_0293 Vinylacetyl-CoA Delta-isomerase OC.635050 Archaea.9975 Crenarchaeota.3238 Sulfolobus.2048 Sulfolobus_islandicus.1979 sid.316 sid:M164_0311 Vinylacetyl-CoA Delta-isomerase OC.635050 Archaea.9975 Crenarchaeota.3238 Sulfolobus.2048 Sulfolobus_islandicus.1979 siy.330 siy:YG5714_0299 Vinylacetyl-CoA Delta-isomerase OC.635050 Archaea.9975 Crenarchaeota.3238 Sulfolobus.2048 Sulfolobus_islandicus.1979 sin.2491 sin:YN1551_2902 Vinylacetyl-CoA Delta-isomerase OC.635050 Archaea.9975 Crenarchaeota.3238 Sulfolobus.2048 Sulfolobus_islandicus.1979 sii.347 sii:LD85_0299 Vinylacetyl-CoA Delta-isomerase OC.635050 Archaea.9975 Crenarchaeota.3238 Sulfolobus.2048 Sulfolobus_islandicus.1979 sih.315 sih:SiH_0300 Vinylacetyl-CoA Delta-isomerase OC.635050 Archaea.9975 Crenarchaeota.3238 Sulfolobus.2048 Sulfolobus_islandicus.1979 sir.306 sir:SiRe_0298 Vinylacetyl-CoA Delta-isomerase OC.635050 Archaea.9975 Crenarchaeota.3238 Sulfolobus.2048 Sulfolobus_islandicus.1979 sic.299 sic:SiL_0284 Aromatic ring hydroxylase OC.635050 Archaea.9975 Crenarchaeota.3238 Sulfolobus.2048 - sula.1227 sula:BFU36_06625 4-hydroxybutyryl-CoA dehydratase OC.635050 Archaea.9975 Crenarchaeota.3238 Metallosphaera.2900 - mse.1202 mse:Msed_1220 Vinylacetyl-CoA Delta-isomerase OC.635050 Archaea.9975 Crenarchaeota.3238 Acidianus.2562 - abri.235 abri:DFR85_01140 4-hydroxybutyryl-CoA dehydratase OC.635050 Archaea.9975 Crenarchaeota.3238 Acidianus.4323 - aman.1052 aman:B6F84_05320 4-hydroxybutyryl-CoA dehydratase OC.635050 Archaea.9975 Crenarchaeota.3238 Pyrobaculum.4145 - pog.2603 pog:Pogu_2659 Aromatic ring hydroxylase OC.635050 Archaea.9975 Crenarchaeota.3238 Vulcanisaeta.970 - vdi.2138 vdi:Vdis_2214 Vinylacetyl-CoA Delta-isomerase OC.635050 Archaea.9975 Crenarchaeota.3238 Vulcanisaeta.970 - vmo.682 vmo:VMUT_0681 Vinylacetyl-CoA Delta-isomerase OC.635050 Archaea.9975 Crenarchaeota.3239 Vulcanisaeta.2702 - vmo.2204 vmo:VMUT_2253 4-hydroxybutyryl-CoA dehydratase (abfD-1) OC.635050 Archaea.9975 Thaumarchaeota.9420 - - ncv.156 ncv:NCAV_0126 putative 4-hydroxybutyryl-CoA dehydratase OC.635051 Archaea.55906 Euryarchaeota.40450 Archaeoglobus.2513 Archaeoglobus_fulgidus.1502 afu.327 afu:AF_0333 4-hydroxyphenylacetate-3-hydroxylase (hpaA-1); K14534 4-hydroxybutyryl-CoA dehydratase / vinylacetyl-CoA-Delta-isomerase [EC:4.2.1.120 5.3.3.3] OC.635051 Archaea.55906 Euryarchaeota.40450 Archaeoglobus.2513 Archaeoglobus_fulgidus.1502 afg.320 afg:AFULGI_00003320 Aromatic ring hydroxylase; K14534 4-hydroxybutyryl-CoA dehydratase / vinylacetyl-CoA-Delta-isomerase [EC:4.2.1.120 5.3.3.3] OC.635052 Archaea.41042 Bathyarchaeota.3177 - - barc.2088 barc:AOA65_2222 hypothetical protein; K14534 4-hydroxybutyryl-CoA dehydratase / vinylacetyl-CoA-Delta-isomerase [EC:4.2.1.120 5.3.3.3] OC.635053 Archaea.47544 Crenarchaeota.19691 - - clg.37 clg:Calag_0024 aromatic ring hydroxylase; K14534 4-hydroxybutyryl-CoA dehydratase / vinylacetyl-CoA-Delta-isomerase [EC:4.2.1.120 5.3.3.3] OC.635054 Archaea.35892 Euryarchaeota.9759 Archaeoglobus.1864 Archaeoglobus_fulgidus.55 afu.1006 afu:AF_1027 4-hydroxyphenylacetate-3-hydroxylase (hpaA-3); K00483 4-hydroxyphenylacetate 3-monooxygenase [EC:1.14.14.9] OC.635054 Archaea.35892 Euryarchaeota.9759 Archaeoglobus.1864 Archaeoglobus_fulgidus.55 afg.1053 afg:AFULGI_00011230 Aromatic ring hydroxylase; K14534 4-hydroxybutyryl-CoA dehydratase / vinylacetyl-CoA-Delta-isomerase [EC:4.2.1.120 5.3.3.3] OC.635054 Archaea.35892 Euryarchaeota.9759 Geoglobus.1954 - gac.1431 gac:GACE_1499 4-hydroxyphenylacetate 3-monooxygenase; K14534 4-hydroxybutyryl-CoA dehydratase / vinylacetyl-CoA-Delta-isomerase [EC:4.2.1.120 5.3.3.3] OC.635055 Archaea.15012 Euryarchaeota.13117 Archaeoglobus.692 Archaeoglobus_fulgidus.2049 afu.865 afu:AF_0885 4-hydroxyphenylacetate-3-hydroxylase (hpaA-2); K00483 4-hydroxyphenylacetate 3-monooxygenase [EC:1.14.14.9] OC.635055 Archaea.15012 Euryarchaeota.13117 Archaeoglobus.692 Archaeoglobus_fulgidus.2049 afg.909 afg:AFULGI_00009740 Aromatic ring hydroxylase; K14534 4-hydroxybutyryl-CoA dehydratase / vinylacetyl-CoA-Delta-isomerase [EC:4.2.1.120 5.3.3.3] OC.635055 Archaea.15012 Euryarchaeota.13117 Archaeoglobus.692 - ast.1655 ast:Asulf_01733 Aromatic ring hydroxylase; K14534 4-hydroxybutyryl-CoA dehydratase / vinylacetyl-CoA-Delta-isomerase [EC:4.2.1.120 5.3.3.3] OC.635055 Archaea.15012 Euryarchaeota.13117 - - fpl.870 fpl:Ferp_0911 Vinylacetyl-CoA Delta-isomerase; K14534 4-hydroxybutyryl-CoA dehydratase / vinylacetyl-CoA-Delta-isomerase [EC:4.2.1.120 5.3.3.3] OC.635055 Archaea.15012 Euryarchaeota.13117 Geoglobus.1212 - gac.575 gac:GACE_0594 4-hydroxyphenylacetate 3-monooxygenase; K14534 4-hydroxybutyryl-CoA dehydratase / vinylacetyl-CoA-Delta-isomerase [EC:4.2.1.120 5.3.3.3] OC.635055 Archaea.15012 Euryarchaeota.13117 Geoglobus.1212 - gah.1598 gah:GAH_01688 Aromatic ring hydroxylase; K14534 4-hydroxybutyryl-CoA dehydratase / vinylacetyl-CoA-Delta-isomerase [EC:4.2.1.120 5.3.3.3] OC.635056 Eukaryotes.526410 Animals.315069 Vertebrates.125312 Fishes.131314 otw.22036 otw:112242974 uncharacterized protein LOC112242974 OC.635056 Archaea.9731 Crenarchaeota.2691 - - sto.814 sto:STK_07260 pheA1; putative phenol hydroxylase large component; K00483 4-hydroxyphenylacetate 3-monooxygenase [EC:1.14.14.9] OC.635056 Archaea.9731 Crenarchaeota.2691 Sulfolobus.361 Sulfolobus_acidocaldarius.1321 sai.2150 sai:Saci_2294 hpaA; 4-hydroxyphenylacetate 3-monooxygenase, oxygenase component; K00483 4-hydroxyphenylacetate 3-monooxygenase [EC:1.14.14.9] OC.635056 Archaea.9731 Crenarchaeota.2691 Sulfolobus.361 Sulfolobus_acidocaldarius.1321 sacn.2201 sacn:SacN8_11190 4-hydroxyphenylacetate 3-hydroxylase; K00483 4-hydroxyphenylacetate 3-monooxygenase [EC:1.14.14.9] OC.635056 Archaea.9731 Crenarchaeota.2691 Sulfolobus.361 Sulfolobus_acidocaldarius.1321 sacr.2244 sacr:SacRon12I_11430 4-hydroxyphenylacetate 3-hydroxylase; K00483 4-hydroxyphenylacetate 3-monooxygenase [EC:1.14.14.9] OC.635056 Archaea.9731 Crenarchaeota.2691 Sulfolobus.361 Sulfolobus_acidocaldarius.1321 sacs.2058 sacs:SUSAZ_10780 4-hydroxyphenylacetate 3-hydroxylase; K00483 4-hydroxyphenylacetate 3-monooxygenase [EC:1.14.14.9] OC.635056 Archaea.9731 Crenarchaeota.2691 Sulfolobus.3425 Sulfolobus_solfataricus.3083 sso.1736 sso:SSO2053 hpaA; 4-hydroxyphenylacetate-3-hydroxylase (hpaA); K00483 4-hydroxyphenylacetate 3-monooxygenase [EC:1.14.14.9] OC.635056 Archaea.9731 Crenarchaeota.2691 Sulfolobus.3425 Sulfolobus_islandicus.2367 sia.615 sia:M1425_0686 4-hydroxyphenylacetate 3-hydroxylase; K00483 4-hydroxyphenylacetate 3-monooxygenase [EC:1.14.14.9] OC.635056 Archaea.9731 Crenarchaeota.2691 Sulfolobus.3425 Sulfolobus_islandicus.2367 sim.618 sim:M1627_0691 4-hydroxyphenylacetate 3-hydroxylase; K00483 4-hydroxyphenylacetate 3-monooxygenase [EC:1.14.14.9] OC.635056 Archaea.9731 Crenarchaeota.2691 Sulfolobus.3425 Sulfolobus_islandicus.2367 sid.687 sid:M164_0713 4-hydroxyphenylacetate 3-hydroxylase; K00483 4-hydroxyphenylacetate 3-monooxygenase [EC:1.14.14.9] OC.635056 Archaea.9731 Crenarchaeota.2691 Sulfolobus.3425 Sulfolobus_islandicus.2367 siy.935 siy:YG5714_1009 4-hydroxyphenylacetate 3-hydroxylase; K00483 4-hydroxyphenylacetate 3-monooxygenase [EC:1.14.14.9] OC.635056 Archaea.9731 Crenarchaeota.2691 Sulfolobus.3425 Sulfolobus_islandicus.2367 sin.1700 sin:YN1551_1864 4-hydroxyphenylacetate 3-hydroxylase; K00483 4-hydroxyphenylacetate 3-monooxygenase [EC:1.14.14.9] OC.635056 Archaea.9731 Crenarchaeota.2691 Sulfolobus.3425 Sulfolobus_islandicus.2367 sih.618 sih:SiH_0629 4-hydroxyphenylacetate 3-hydroxylase; K00483 4-hydroxyphenylacetate 3-monooxygenase [EC:1.14.14.9] OC.635056 Archaea.9731 Crenarchaeota.2691 Sulfolobus.3425 Sulfolobus_islandicus.2367 sir.690 sir:SiRe_0706 4-hydroxyphenylacetate 3-hydroxylase; K00483 4-hydroxyphenylacetate 3-monooxygenase [EC:1.14.14.9] OC.635056 Archaea.9731 Crenarchaeota.2691 Sulfolobus.3425 Sulfolobus_islandicus.2367 sic.732 sic:SiL_0742 Aromatic ring hydroxylase; K00483 4-hydroxyphenylacetate 3-monooxygenase [EC:1.14.14.9] OC.635056 Archaea.9731 Crenarchaeota.2691 Sulfolobus.3425 Sulfolobus_islandicus.2368 sis.803 sis:LS215_0936 4-hydroxyphenylacetate 3-hydroxylase; K00483 4-hydroxyphenylacetate 3-monooxygenase [EC:1.14.14.9] OC.635056 Archaea.9731 Crenarchaeota.2691 Sulfolobus.3425 Sulfolobus_islandicus.2369 sii.698 sii:LD85_0739 4-hydroxyphenylacetate 3-hydroxylase; K00483 4-hydroxyphenylacetate 3-monooxygenase [EC:1.14.14.9] OC.635056 Archaea.9731 Crenarchaeota.2691 Sulfolobus.3425 - sula.1512 sula:BFU36_08220 4-hydroxyphenylacetate 3-hydroxylase; K00483 4-hydroxyphenylacetate 3-monooxygenase [EC:1.14.14.9] OC.635056 Archaea.9731 Crenarchaeota.2691 Metallosphaera.78 - mse.989 mse:Msed_0996 4-hydroxyphenylacetate 3-monooxygenase oxygenase component; K00483 4-hydroxyphenylacetate 3-monooxygenase [EC:1.14.14.9] OC.635056 Archaea.9731 Crenarchaeota.2691 Metallosphaera.78 - mcn.1175 mcn:Mcup_1186 4-hydroxyphenylacetate 3-hydroxylase; K00483 4-hydroxyphenylacetate 3-monooxygenase [EC:1.14.14.9] OC.635056 Archaea.9731 Crenarchaeota.2691 Metallosphaera.78 - mhk.185 mhk:DFR87_00965 4-hydroxyphenylacetate 3-hydroxylase; K00483 4-hydroxyphenylacetate 3-monooxygenase [EC:1.14.14.9] OC.635056 Archaea.9731 Crenarchaeota.2691 Metallosphaera.1218 - mse.1748 mse:Msed_1776 4-hydroxyphenylacetate 3-hydroxylase; K00483 4-hydroxyphenylacetate 3-monooxygenase [EC:1.14.14.9] OC.635056 Archaea.9731 Crenarchaeota.2691 Metallosphaera.1218 - mcn.456 mcn:Mcup_0455 4-hydroxyphenylacetate 3-hydroxylase; K00483 4-hydroxyphenylacetate 3-monooxygenase [EC:1.14.14.9] OC.635056 Archaea.9731 Crenarchaeota.2691 Metallosphaera.1218 - mhk.1738 mhk:DFR87_09780 4-hydroxyphenylacetate 3-hydroxylase; K00483 4-hydroxyphenylacetate 3-monooxygenase [EC:1.14.14.9] OC.635056 Archaea.9731 Crenarchaeota.2691 Acidianus.2210 - aman.1065 aman:B6F84_05385 4-hydroxyphenylacetate 3-hydroxylase; K00483 4-hydroxyphenylacetate 3-monooxygenase [EC:1.14.14.9] OC.635056 Archaea.9731 Crenarchaeota.2691 Acidianus.2210 - asul.902 asul:DFR86_04660 4-hydroxyphenylacetate 3-hydroxylase; K00483 4-hydroxyphenylacetate 3-monooxygenase [EC:1.14.14.9] OC.635056 Archaea.9731 Crenarchaeota.2691 Acidianus.3543 - abri.2727 abri:DFR85_15425 4-hydroxyphenylacetate 3-hydroxylase; K00483 4-hydroxyphenylacetate 3-monooxygenase [EC:1.14.14.9] OC.635056 Archaea.9731 Crenarchaeota.2691 Pyrobaculum.3992 - pog.1342 pog:Pogu_1357 Aromatic ring hydroxylase; K00483 4-hydroxyphenylacetate 3-monooxygenase [EC:1.14.14.9] OC.635056 Archaea.58629 Euryarchaeota.43510 Halobacterium.4510 - hdl.3053 hdl:HALDL1_15845 MFS transporter; K00483 4-hydroxyphenylacetate 3-monooxygenase [EC:1.14.14.9]