# OC Root 2nd 3rd 4th 5th PC Gene/Definition OC.652780 Archaea.7938 Euryarchaeota.15516 Methanobacterium.1934 - mel.1262 mel:Metbo_1265 thiazole biosynthetic enzyme; K22699 sulfide-dependent adenosine diphosphate thiazole synthase [EC:2.4.2.59] OC.652780 Archaea.7938 Euryarchaeota.15516 Methanobacterium.1934 - mew.970 mew:MSWAN_0974 thiazole biosynthetic enzyme; K22699 sulfide-dependent adenosine diphosphate thiazole synthase [EC:2.4.2.59] OC.652780 Archaea.7938 Euryarchaeota.15516 Methanobacterium.1934 Methanobacterium_sp_.1162 meth.1114 meth:MBMB1_1137 putative ribose 1,5-bisphosphate isomerase; K22699 sulfide-dependent adenosine diphosphate thiazole synthase [EC:2.4.2.59] OC.652780 Archaea.7938 Euryarchaeota.15516 Methanobacterium.1934 Methanobacterium_formicicum.321 mfc.1317 mfc:BRM9_1347 thiazole biosynthesis protein; K22699 sulfide-dependent adenosine diphosphate thiazole synthase [EC:2.4.2.59] OC.652780 Archaea.7938 Euryarchaeota.15516 Methanobacterium.1934 Methanobacterium_formicicum.321 mfi.1972 mfi:DSM1535_2031 putative ribose 1,5-bisphosphate isomerase; K22699 sulfide-dependent adenosine diphosphate thiazole synthase [EC:2.4.2.59] OC.652780 Archaea.7938 Euryarchaeota.15516 Methanobacterium.1934 - mcub.991 mcub:MCBB_1020 putative ribose 1,5-bisphosphate isomerase {ECO:0000255|HAMAP-Rule:MF_00304}; K22699 sulfide-dependent adenosine diphosphate thiazole synthase [EC:2.4.2.59] OC.652780 Archaea.7938 Euryarchaeota.15516 Pyrococcus.2742 Pyrococcus_sp_.1593 pyn.1578 pyn:PNA2_1583 ribulose-1,5-biphosphate synthetase; K22699 sulfide-dependent adenosine diphosphate thiazole synthase [EC:2.4.2.59] OC.652780 Archaea.7938 Euryarchaeota.15516 Pyrococcus.2742 - pya.834 pya:PYCH_08650 putative thiazole biosynthetic enzyme; K22699 sulfide-dependent adenosine diphosphate thiazole synthase [EC:2.4.2.59] OC.652780 Archaea.7938 Euryarchaeota.15516 - - ppac.1692 ppac:PAP_08770 ribonucleoside-triphosphate reductase; K22699 sulfide-dependent adenosine diphosphate thiazole synthase [EC:2.4.2.59] OC.652780 Archaea.7938 Euryarchaeota.15517 Methanococcoides.2343 - mmet.863 mmet:MCMEM_0840 Thiazole biosynthetic enzyme Thi4; K22699 sulfide-dependent adenosine diphosphate thiazole synthase [EC:2.4.2.59] OC.652780 Archaea.7938 Euryarchaeota.15516 Methanocella.2534 - mez.1534 mez:Mtc_1604 thi4-1; thiazole biosynthesis enzyme, flavoprotein; K22699 sulfide-dependent adenosine diphosphate thiazole synthase [EC:2.4.2.59] OC.652780 Archaea.7938 Euryarchaeota.15516 Halobacterium.164 Halobacterium_salinarum.1203 hal.2132 hal:VNG_2604G thi1; thiamine biosynthetic enzyme; K22699 sulfide-dependent adenosine diphosphate thiazole synthase [EC:2.4.2.59] OC.652780 Archaea.7938 Euryarchaeota.15516 Halobacterium.164 Halobacterium_salinarum.1203 hsl.2138 hsl:OE_4651F thi4; thiamine thiazole synthase; K22699 sulfide-dependent adenosine diphosphate thiazole synthase [EC:2.4.2.59] OC.652780 Archaea.7938 Euryarchaeota.15516 Halobacterium.164 - hhb.171 hhb:Hhub_1122 thi4; thiamine thiazole synthase; K22699 sulfide-dependent adenosine diphosphate thiazole synthase [EC:2.4.2.59] OC.652780 Archaea.7938 Euryarchaeota.15516 - - hje.2662 hje:HacjB3_12970 ribulose-1,5-biphosphate synthetase; K22699 sulfide-dependent adenosine diphosphate thiazole synthase [EC:2.4.2.59] OC.652780 Archaea.7938 Euryarchaeota.15516 Halanaeroarchaeum.1458 - hsu.325 hsu:HLASF_0331 ribulose-1,5-biphosphate synthetase; K22699 sulfide-dependent adenosine diphosphate thiazole synthase [EC:2.4.2.59] OC.652780 Archaea.7938 Euryarchaeota.15516 Halanaeroarchaeum.1458 - hsf.323 hsf:HLASA_0330 ribulose-1,5-biphosphate synthetase; K22699 sulfide-dependent adenosine diphosphate thiazole synthase [EC:2.4.2.59] OC.652780 Archaea.7938 Euryarchaeota.15516 Haloarcula.386 - hma.2380 hma:rrnAC1782 thi1; putative thiazole biosynthetic enzyme; K22699 sulfide-dependent adenosine diphosphate thiazole synthase [EC:2.4.2.59] OC.652780 Archaea.7938 Euryarchaeota.15516 Haloarcula.386 Haloarcula_hispanica.1362 hhi.2266 hhi:HAH_2313 thi1; ribulose-1,5-biphosphate synthetase; K22699 sulfide-dependent adenosine diphosphate thiazole synthase [EC:2.4.2.59] OC.652780 Archaea.7938 Euryarchaeota.15516 Haloarcula.386 Haloarcula_hispanica.1362 hhn.2311 hhn:HISP_11780 ribonucleoside-triphosphate reductase; K22699 sulfide-dependent adenosine diphosphate thiazole synthase [EC:2.4.2.59] OC.652780 Archaea.7938 Euryarchaeota.15516 Haloarcula.386 - hab.784 hab:SG26_04110 ribonucleoside-triphosphate reductase; K22699 sulfide-dependent adenosine diphosphate thiazole synthase [EC:2.4.2.59] OC.652780 Archaea.7938 Euryarchaeota.15516 Haloarcula.386 - hta.2195 hta:BVU17_11255 thiazole biosynthesis enzyme; K22699 sulfide-dependent adenosine diphosphate thiazole synthase [EC:2.4.2.59] OC.652780 Archaea.7938 Euryarchaeota.15516 Natronomonas.979 - nph.2523 nph:NP_5174A thi4; thiamine thiazole synthase; K22699 sulfide-dependent adenosine diphosphate thiazole synthase [EC:2.4.2.59] OC.652780 Archaea.7938 Euryarchaeota.15516 Natronomonas.979 - nmo.2611 nmo:Nmlp_3882 thi4; thiamine thiazole synthase; K22699 sulfide-dependent adenosine diphosphate thiazole synthase [EC:2.4.2.59] OC.652780 Archaea.7938 Euryarchaeota.15516 Halorhabdus.1119 - hut.2658 hut:Huta_2718 thiazole biosynthesis enzyme; K22699 sulfide-dependent adenosine diphosphate thiazole synthase [EC:2.4.2.59] OC.652780 Archaea.7938 Euryarchaeota.15516 Halorhabdus.1119 - hti.2404 hti:HTIA_2465 thiazole biosynthetic enzyme Thi4 / ribose 1,5-bisphosphate or 5-ribose-1,2-cyclic phosphate dehydrogenase; K22699 sulfide-dependent adenosine diphosphate thiazole synthase [EC:2.4.2.59] OC.652780 Archaea.7938 Euryarchaeota.15516 - - hmu.56 hmu:Hmuk_0002 thiazole biosynthesis enzyme; K22699 sulfide-dependent adenosine diphosphate thiazole synthase [EC:2.4.2.59] OC.652780 Archaea.7938 Euryarchaeota.15516 - - hali.1129 hali:BV210_05585 ribose 1,5-bisphosphate isomerase; K22699 sulfide-dependent adenosine diphosphate thiazole synthase [EC:2.4.2.59] OC.652780 Archaea.7938 Euryarchaeota.15516 - - harc.1827 harc:HARCEL1_09615 ribose 1,5-bisphosphate isomerase; K22699 sulfide-dependent adenosine diphosphate thiazole synthase [EC:2.4.2.59] OC.652780 Archaea.7938 Euryarchaeota.15516 Haloquadratum.1504 - hwa.288 hwa:HQ_1276A thi4; thiamine thiazole synthase; K22699 sulfide-dependent adenosine diphosphate thiazole synthase [EC:2.4.2.59] OC.652780 Archaea.7938 Euryarchaeota.15516 Haloquadratum.1504 - hwc.295 hwc:Hqrw_1306 thi4; thiamine thiazole synthase; K22699 sulfide-dependent adenosine diphosphate thiazole synthase [EC:2.4.2.59] OC.652780 Archaea.7938 Euryarchaeota.15516 Haloferax.2795 - hvo.689 hvo:HVO_0665 thi4; thiamine thiazole synthase; K22699 sulfide-dependent adenosine diphosphate thiazole synthase [EC:2.4.2.59] OC.652780 Archaea.7938 Euryarchaeota.15516 Haloferax.2795 - hme.638 hme:HFX_0634 ribulose-1,5-biphosphate synthetase; K22699 sulfide-dependent adenosine diphosphate thiazole synthase [EC:2.4.2.59] OC.652780 Archaea.7938 Euryarchaeota.15516 Haloferax.2795 - hgi.629 hgi:ABY42_03175 ribonucleoside-triphosphate reductase; K22699 sulfide-dependent adenosine diphosphate thiazole synthase [EC:2.4.2.59] OC.652780 Archaea.7938 Euryarchaeota.15516 - - hbo.2473 hbo:Hbor_25460 thiazole-adenylate synthase; K22699 sulfide-dependent adenosine diphosphate thiazole synthase [EC:2.4.2.59] OC.652780 Archaea.7938 Euryarchaeota.15516 Haloplanus.300 - haq.1225 haq:DU484_06390 thiazole biosynthesis protein; K22699 sulfide-dependent adenosine diphosphate thiazole synthase [EC:2.4.2.59] OC.652780 Archaea.7938 Euryarchaeota.15516 Haloplanus.300 - haj.1293 haj:DU500_06660 thiazole biosynthesis protein; K22699 sulfide-dependent adenosine diphosphate thiazole synthase [EC:2.4.2.59] OC.652780 Archaea.7938 Euryarchaeota.15516 - - hla.2906 hla:Hlac_2980 thiazole biosynthesis enzyme; K22699 sulfide-dependent adenosine diphosphate thiazole synthase [EC:2.4.2.59] OC.652780 Archaea.7938 Euryarchaeota.15516 - - srub.476 srub:C2R22_02145 ribose 1,5-bisphosphate isomerase; K22699 sulfide-dependent adenosine diphosphate thiazole synthase [EC:2.4.2.59] OC.652780 Archaea.7938 Euryarchaeota.15516 - - hae.1069 hae:halTADL_1093 thiamine thiazole synthase; K22699 sulfide-dependent adenosine diphosphate thiazole synthase [EC:2.4.2.59] OC.652780 Archaea.7938 Euryarchaeota.15516 - - hah.3332 hah:Halar_3704 thiazole biosynthetic enzyme; K22699 sulfide-dependent adenosine diphosphate thiazole synthase [EC:2.4.2.59] OC.652780 Archaea.7938 Euryarchaeota.15516 Haloterrigena.4760 - htu.1514 htu:Htur_1462 thiazole biosynthesis enzyme; K22699 sulfide-dependent adenosine diphosphate thiazole synthase [EC:2.4.2.59] OC.652780 Archaea.7938 Euryarchaeota.15516 Haloterrigena.1350 - hda.413 hda:BB347_01930 ribose 1,5-bisphosphate isomerase; K22699 sulfide-dependent adenosine diphosphate thiazole synthase [EC:2.4.2.59] OC.652780 Archaea.7938 Euryarchaeota.15516 - - nmg.2371 nmg:Nmag_2419 thi4; thiamine thiazole synthase; K22699 sulfide-dependent adenosine diphosphate thiazole synthase [EC:2.4.2.59] OC.652780 Archaea.7938 Euryarchaeota.15516 - - hxa.2775 hxa:Halxa_2863 thiazole biosynthetic enzyme; K22699 sulfide-dependent adenosine diphosphate thiazole synthase [EC:2.4.2.59] OC.652780 Archaea.7938 Euryarchaeota.15516 Natrinema.1461 - nat.3551 nat:NJ7G_3680 thiazole biosynthesis enzyme; K22699 sulfide-dependent adenosine diphosphate thiazole synthase [EC:2.4.2.59] OC.652780 Archaea.7938 Euryarchaeota.15516 Natrinema.1461 - npe.2656 npe:Natpe_2830 thiazole biosynthesis enzyme; K22699 sulfide-dependent adenosine diphosphate thiazole synthase [EC:2.4.2.59] OC.652780 Archaea.7938 Euryarchaeota.15516 - - nge.900 nge:Natgr_0926 thiazole biosynthesis enzyme; K22699 sulfide-dependent adenosine diphosphate thiazole synthase [EC:2.4.2.59] OC.652780 Archaea.7938 Euryarchaeota.15516 - - hru.1094 hru:Halru_1150 thiazole biosynthesis enzyme; K22699 sulfide-dependent adenosine diphosphate thiazole synthase [EC:2.4.2.59] OC.652780 Archaea.7938 Euryarchaeota.15516 - - nou.582 nou:Natoc_0532 thiazole-adenylate synthase; K22699 sulfide-dependent adenosine diphosphate thiazole synthase [EC:2.4.2.59] OC.652780 Archaea.7938 Euryarchaeota.15516 - - sali.1894 sali:L593_09560 ribulose-1,5-biphosphate synthetase; K22699 sulfide-dependent adenosine diphosphate thiazole synthase [EC:2.4.2.59] OC.652780 Archaea.7938 Euryarchaeota.15516 - - hlr.1988 hlr:HALLA_10200 ribonucleoside-triphosphate reductase; K22699 sulfide-dependent adenosine diphosphate thiazole synthase [EC:2.4.2.59] OC.652780 Archaea.7938 Euryarchaeota.15516 - - hlc.3246 hlc:CHINAEXTREME16945 ribose 1,5-bisphosphate isomerase; K22699 sulfide-dependent adenosine diphosphate thiazole synthase [EC:2.4.2.59] OC.652780 Archaea.7938 Euryarchaeota.15516 Natronolimnobius.133 - nag.1119 nag:AArcMg_1121 thiamine thiazole synthase; K22699 sulfide-dependent adenosine diphosphate thiazole synthase [EC:2.4.2.59] OC.652780 Archaea.7938 Euryarchaeota.15516 Natronolimnobius.133 - nan.2456 nan:AArc1_2501 Archaeal ribulose 1,5-bisphosphate synthetase; K22699 sulfide-dependent adenosine diphosphate thiazole synthase [EC:2.4.2.59] OC.652780 Archaea.7938 Euryarchaeota.15516 - - naj.701 naj:B1756_03455 ribose 1,5-bisphosphate isomerase; K22699 sulfide-dependent adenosine diphosphate thiazole synthase [EC:2.4.2.59] OC.652780 Archaea.7938 Crenarchaeota.13727 Aeropyrum.371 - ape.1388 ape:APE_2149.1 thiazole biosynthetic enzyme Thi4; K22699 sulfide-dependent adenosine diphosphate thiazole synthase [EC:2.4.2.59] OC.652780 Archaea.7938 Crenarchaeota.13727 Aeropyrum.371 - acj.1341 acj:ACAM_1344 ribulose-1,5-biphosphate synthetase; K22699 sulfide-dependent adenosine diphosphate thiazole synthase [EC:2.4.2.59] OC.652780 Archaea.7938 Thaumarchaeota.1106 Nitrosopumilus.489 - nmr.682 nmr:Nmar_0678 thiazole biosynthesis enzyme; K22699 sulfide-dependent adenosine diphosphate thiazole synthase [EC:2.4.2.59] OC.652780 Archaea.7938 Thaumarchaeota.1106 Nitrosopumilus.1634 - nir.687 nir:NSED_03435 ribulose-1,5-biphosphate synthetase; K22699 sulfide-dependent adenosine diphosphate thiazole synthase [EC:2.4.2.59] OC.652780 Archaea.7938 Thaumarchaeota.1106 Nitrosopumilus.489 - nid.1564 nid:NPIRD3C_1584 putative thiazole biosynthetic enzyme; K22699 sulfide-dependent adenosine diphosphate thiazole synthase [EC:2.4.2.59] OC.652780 Archaea.7938 Thaumarchaeota.1106 Nitrosopumilus.1634 - nin.1444 nin:NADRNF5_1474 putative ribose 1,5-bisphosphate isomerase; K22699 sulfide-dependent adenosine diphosphate thiazole synthase [EC:2.4.2.59] OC.652780 Archaea.7938 Thaumarchaeota.1106 - - nkr.669 nkr:NKOR_03495 ribulose-1,5-biphosphate synthetase; K22699 sulfide-dependent adenosine diphosphate thiazole synthase [EC:2.4.2.59] OC.652780 Archaea.7938 Thaumarchaeota.1106 - - nct.1006 nct:NMSP_1025 Putative ribose 1,5-bisphosphate isomerase; K22699 sulfide-dependent adenosine diphosphate thiazole synthase [EC:2.4.2.59] OC.652780 Archaea.7938 Thaumarchaeota.1106 - - csy.416 csy:CENSYa_0361 thiazole biosynthetic protein; K22699 sulfide-dependent adenosine diphosphate thiazole synthase [EC:2.4.2.59] OC.652780 Archaea.7938 Thaumarchaeota.1106 Nitrososphaera.1121 - nga.2043 nga:Ngar_c21660 putative thiazole biosynthetic enzyme; K22699 sulfide-dependent adenosine diphosphate thiazole synthase [EC:2.4.2.59] OC.652780 Archaea.7938 Thaumarchaeota.1106 Nitrososphaera.1121 - nvn.808 nvn:NVIE_008130 putative thiazole biosynthetic enzyme; K22699 sulfide-dependent adenosine diphosphate thiazole synthase [EC:2.4.2.59] OC.652780 Archaea.7938 Thaumarchaeota.1106 Nitrososphaera.1121 - nev.2163 nev:NTE_02257 thiazole-adenylate synthase; K22699 sulfide-dependent adenosine diphosphate thiazole synthase [EC:2.4.2.59] OC.652780 Archaea.7938 Thaumarchaeota.1106 - - taa.2539 taa:NMY3_02935 ribulose-1,5-biphosphate synthetase; K22699 sulfide-dependent adenosine diphosphate thiazole synthase [EC:2.4.2.59] OC.652780 Archaea.7938 Thaumarchaeota.1106 - - ncv.415 ncv:NCAV_0396 thi; Thiamine thiazole synthase; K22699 sulfide-dependent adenosine diphosphate thiazole synthase [EC:2.4.2.59] OC.652780 Archaea.7938 Thaumarchaeota.1106 - - nbv.534 nbv:T478_0555 thiazole biosynthesis enzyme; K22699 sulfide-dependent adenosine diphosphate thiazole synthase [EC:2.4.2.59] OC.652780 Archaea.7938 Thaumarchaeota.1106 - - tah.513 tah:SU86_002805 ribonucleoside-triphosphate reductase; K22699 sulfide-dependent adenosine diphosphate thiazole synthase [EC:2.4.2.59] OC.652780 Archaea.7938 Thaumarchaeota.1106 - - ndv.780 ndv:NDEV_0758 putative ribose 1,5-bisphosphate isomerase; K22699 sulfide-dependent adenosine diphosphate thiazole synthase [EC:2.4.2.59]