# OC Root 2nd 3rd 4th 5th 6th PC Gene/Definition OC.658493 Bacteria.396662 Proteobacteria.180481 Gammaproteobacteria.72952 Legionella.5517 - lha.630 lha:LHA_0652 tRNA methyl transferase-like protein OC.658493 Bacteria.396662 Proteobacteria.180481 Gammaproteobacteria.72952 Legionella.5517 - lcd.2287 lcd:clem_11750 tRNA-specific 2-thiouridylase MnmA OC.658493 Bacteria.396662 Proteobacteria.180481 Gammaproteobacteria.72952 Legionella.5517 - llg.523 llg:44548918_00533 tRNA-specific 2-thiouridylase MnmA OC.658493 Bacteria.396662 Proteobacteria.180481 Gammaproteobacteria.72952 - - tmc.2498 tmc:LMI_2680 tRNA methyl transferase-like protein OC.658493 Bacteria.396662 Proteobacteria.180481 Gammaproteobacteria.72952 Methylomonas.1011 - mmt.509 mmt:Metme_0468 tRNA(5-methylaminomethyl-2-thiouridylate)-methyl transferase OC.658493 Bacteria.396662 Proteobacteria.180481 Gammaproteobacteria.72952 Methylomonas.1011 - mdh.196 mdh:AYM39_00730 tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase OC.658493 Bacteria.396662 Proteobacteria.180481 Gammaproteobacteria.72952 Methylomonas.1011 - mko.204 mko:MKLM6_0184 tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase OC.658493 Bacteria.396662 Proteobacteria.180481 Gammaproteobacteria.72952 - - mah.515 mah:MEALZ_0458 tRNA methyl transferase-like protein OC.658493 Bacteria.396662 Proteobacteria.180481 Gammaproteobacteria.72952 - - mpsy.3663 mpsy:CEK71_19565 tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase OC.658493 Bacteria.396662 Proteobacteria.180481 Gammaproteobacteria.72952 Francisella.2317 Francisella_philomiragia.961 fph.1810 fph:Fphi_1863 conserved hypothetical protein OC.658493 Bacteria.396662 Proteobacteria.180481 Gammaproteobacteria.72952 Francisella.2317 Francisella_philomiragia.961 fpt.414 fpt:BZ13_139 tRNA methyl transferase family protein OC.658493 Bacteria.396662 Proteobacteria.180481 Gammaproteobacteria.72952 Francisella.2317 Francisella_philomiragia.961 fpi.237 fpi:BF30_123 tRNA methyl transferase family protein OC.658493 Bacteria.396662 Proteobacteria.180481 Gammaproteobacteria.72952 Francisella.2317 Francisella_philomiragia.961 fpm.1094 fpm:LA56_328 tRNA methyl transferase family protein OC.658493 Bacteria.396662 Proteobacteria.180481 Gammaproteobacteria.72952 Francisella.2317 Francisella_philomiragia.961 fpx.457 fpx:KU46_1429 tRNA methyl transferase family protein OC.658493 Bacteria.396662 Proteobacteria.180481 Gammaproteobacteria.72952 Francisella.2317 Francisella_philomiragia.961 fpz.1916 fpz:LA55_888 tRNA methyl transferase family protein OC.658493 Bacteria.396662 Proteobacteria.180481 Gammaproteobacteria.72952 Francisella.2317 Francisella_philomiragia.961 fpj.614 fpj:LA02_1593 tRNA methyl transferase family protein OC.658493 Bacteria.396662 Proteobacteria.180481 Gammaproteobacteria.72952 Francisella.2317 Francisella_noatunensis.235 fna.1248 fna:OOM_1422 hypothetical protein OC.658493 Bacteria.396662 Proteobacteria.180481 Gammaproteobacteria.72952 Francisella.2317 Francisella_noatunensis.235 fnl.783 fnl:M973_04830 tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase OC.658493 Bacteria.396662 Proteobacteria.180481 Gammaproteobacteria.72952 Francisella.2317 Francisella_sp_.308 frf.381 frf:LO80_02035 tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase OC.658493 Bacteria.396662 Proteobacteria.180481 Gammaproteobacteria.72952 Francisella.2317 - fha.711 fha:CDV26_04535 tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase OC.658493 Bacteria.396662 Proteobacteria.180481 Gammaproteobacteria.72952 Francisella.2317 Francisella_sp_.308 frx.1182 frx:F7310_06170 tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase OC.658493 Bacteria.396662 Proteobacteria.180481 Gammaproteobacteria.72952 Francisella.2317 Francisella_sp_.2757 frm.930 frm:BBG19_0953 tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase OC.658493 Bacteria.396662 Proteobacteria.180481 Gammaproteobacteria.72952 - - fgu.828 fgu:SD28_04565 tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase OC.658493 Bacteria.396662 Proteobacteria.180481 Gammaproteobacteria.72952 Methylophaga.901 - mej.452 mej:Q7A_1287 tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase OC.658493 Bacteria.396662 Proteobacteria.180481 Gammaproteobacteria.72952 Methylophaga.901 - mec.2229 mec:Q7C_587 tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase OC.658493 Bacteria.396662 Proteobacteria.180481 Gammaproteobacteria.72952 Cycloclasticus.186 Cycloclasticus_sp_.1167 cyq.25 cyq:Q91_0023 tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase OC.658493 Bacteria.396662 Proteobacteria.180481 Gammaproteobacteria.72952 Cycloclasticus.186 - cza.61 cza:CYCME_0023 tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase OC.658493 Bacteria.396662 Proteobacteria.180481 Gammaproteobacteria.72952 Cycloclasticus.186 Cycloclasticus_sp_.1167 cyy.266 cyy:CPC19_01410 tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase OC.658493 Bacteria.396662 Proteobacteria.180481 Gammaproteobacteria.72952 Nitrosococcus.1950 - noc.2509 noc:Noc_2654 conserved hypothetical protein OC.658493 Bacteria.396662 Proteobacteria.180481 Gammaproteobacteria.72952 Nitrosococcus.1950 - nhl.577 nhl:Nhal_0549 tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase OC.658493 Bacteria.396662 Proteobacteria.180481 Gammaproteobacteria.72952 Nitrosococcus.1950 - nwa.454 nwa:Nwat_0463 tRNA methyl transferase-like protein OC.658493 Bacteria.396662 Proteobacteria.180481 Gammaproteobacteria.72952 - - tee.523 tee:Tel_02435 tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase OC.658493 Bacteria.396662 Proteobacteria.180481 Gammaproteobacteria.72952 - - ntt.550 ntt:TAO_0541 tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase OC.658493 Bacteria.396662 Proteobacteria.180481 Gammaproteobacteria.72952 Halorhodospira.1255 - hha.1191 hha:Hhal_1219 tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase OC.658493 Bacteria.396662 Proteobacteria.180481 Gammaproteobacteria.72952 - - aprs.2902 aprs:BI364_16125 tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase OC.658493 Bacteria.396662 Proteobacteria.180481 Gammaproteobacteria.72952 Alcanivorax.1369 - abo.2264 abo:ABO_2264 trmU; tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase OC.658493 Bacteria.396662 Proteobacteria.180481 Gammaproteobacteria.72952 Alcanivorax.1369 - adi.626 adi:B5T_00619 trmU; tRNA methyl transferase-like protein OC.658493 Bacteria.396662 Proteobacteria.180481 Gammaproteobacteria.72952 Alcanivorax.1369 - apac.357 apac:S7S_01545 tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase OC.658493 Bacteria.396662 Proteobacteria.180481 Gammaproteobacteria.72952 Alcanivorax.1369 - aln.2319 aln:AS19_23200 tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase OC.658493 Bacteria.396662 Proteobacteria.180481 Gammaproteobacteria.72952 Alcanivorax.1369 - axe.618 axe:P40_02865 tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase OC.658493 Bacteria.396662 Proteobacteria.180481 Gammaproteobacteria.72952 - - kak.1595 kak:Kalk_08285 tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase OC.658493 Bacteria.396662 Proteobacteria.180481 Gammaproteobacteria.72952 Kangiella.1261 - kko.2260 kko:Kkor_2282 tRNA(5-methylaminomethyl-2-thiouridylate)-methyl transferase OC.658493 Bacteria.396662 Proteobacteria.180481 Gammaproteobacteria.72952 Kangiella.1261 - kge.307 kge:TQ33_0310 tRNA(5-methylaminomethyl-2-thiouridylate)-methyl transferase OC.658493 Bacteria.396662 Proteobacteria.180481 Gammaproteobacteria.72952 Kangiella.1261 - ksd.1569 ksd:KS2013_328 tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase OC.658493 Bacteria.396662 Proteobacteria.180481 Gammaproteobacteria.72952 Kangiella.1261 - kpd.2068 kpd:CW740_10660 tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase OC.658493 Bacteria.396662 Proteobacteria.180481 Gammaproteobacteria.72952 - - gbi.2144 gbi:PG2T_11560 tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase OC.658493 Bacteria.396662 Proteobacteria.180481 Gammaproteobacteria.72952 - - slim.2470 slim:SCL_2545 tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase OC.658493 Bacteria.396662 Proteobacteria.180481 Gammaproteobacteria.72952 - - sva.3473 sva:SVA_3618 tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase OC.658493 Bacteria.396662 Proteobacteria.180481 Gammaproteobacteria.72952 - - acii.360 acii:C4901_01190 tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase OC.658493 Bacteria.396662 Proteobacteria.180481 Gammaproteobacteria.72952 - - tbn.2653 tbn:TBH_C2762 thiamine biosynthesis protein OC.658493 Bacteria.396662 Proteobacteria.180481 Gammaproteobacteria.72952 - - seds.2399 seds:AAY24_12865 tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase OC.658493 Bacteria.396662 Proteobacteria.180481 Gammaproteobacteria.72952 Thioglobus.668 - tho.377 tho:SP60_01945 tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase OC.658493 Bacteria.396662 Proteobacteria.180481 Gammaproteobacteria.72952 - - ttc.202 ttc:FOKN1_0185 tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase OC.658493 Bacteria.396662 Proteobacteria.180481 Gammaproteobacteria.72952 - - rma.790 rma:Rmag_0880 conserved hypothetical protein OC.658493 Bacteria.396662 Proteobacteria.180481 Gammaproteobacteria.72952 - - vok.770 vok:COSY_0804 conserved hypothetical protein OC.658493 Bacteria.396662 Proteobacteria.180481 Gammaproteobacteria.72952 - - ebh.1213 ebh:BSEPE_1273 tRNA-specific 2-thiouridylase OC.658493 Bacteria.396662 Proteobacteria.180481 Gammaproteobacteria.72952 - - gpb.827 gpb:HDN1F_07390 thiI; predicted thiamine biosynthesis protein OC.658493 Bacteria.396662 Proteobacteria.180481 Gammaproteobacteria.72952 - - enm.20 enm:EBS_0010 tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase OC.658493 Bacteria.396662 Proteobacteria.272119 Deltaproteobacteria.32780 Geobacter.4683 Geobacter_sulfurreducens.2514 gsu.428 gsu:GSU0434 thiamin biosynthesis protein ThiI-related adenine nucleotide alpha hydrolase superfamily protein OC.658493 Bacteria.396662 Proteobacteria.272119 Deltaproteobacteria.32780 Geobacter.4683 Geobacter_sulfurreducens.2514 gsk.404 gsk:KN400_0403 thiamin biosynthesis protein ThiI-related adenine nucleotide alpha hydrolase superfamily protein OC.658493 Bacteria.396662 Proteobacteria.272119 Deltaproteobacteria.32780 Geobacter.4683 - gme.3262 gme:Gmet_3402 thiamin biosynthesis protein ThiI-related adenine nucleotide alpha hydrolase superfamily protein OC.658493 Bacteria.396662 Proteobacteria.272119 Deltaproteobacteria.32780 Geobacter.4683 - gur.4011 gur:Gura_4272 thiamine biosynthesis protein OC.658493 Bacteria.396662 Proteobacteria.272119 Deltaproteobacteria.32780 Geobacter.11127 - glo.3050 glo:Glov_3219 thiamine biosynthesis protein OC.658493 Bacteria.396662 Proteobacteria.272119 Deltaproteobacteria.32780 Geobacter.4683 - gbm.110 gbm:Gbem_0082 thiamin biosynthesis protein ThiI-related adenine nucleotide alpha hydrolase superfamily protein OC.658493 Bacteria.396662 Proteobacteria.272119 Deltaproteobacteria.32780 Geobacter.4683 - geo.453 geo:Geob_0441 thiamin biosynthesis protein ThiI-related adenine nucleotide alpha-hydrolase superfamily protein OC.658493 Bacteria.396662 Proteobacteria.272119 Deltaproteobacteria.32780 Geobacter.4683 Geobacter_sp_.737 gem.83 gem:GM21_0065 thiamine biosynthesis protein OC.658493 Bacteria.396662 Proteobacteria.272119 Deltaproteobacteria.32780 Geobacter.4683 Geobacter_sp_.737 geb.274 geb:GM18_0225 Thiamine biosynthesis protein-like protein OC.658493 Bacteria.396662 Proteobacteria.272119 Deltaproteobacteria.32780 Geobacter.4683 - gpi.2789 gpi:GPICK_15560 thiamine biosynthesis protein ThiI OC.658493 Bacteria.396662 Proteobacteria.272119 Deltaproteobacteria.32780 Geobacter.4683 - gao.351 gao:A2G06_01980 thiamine biosynthesis protein ThiI OC.658493 Bacteria.396662 Proteobacteria.272119 Deltaproteobacteria.32780 Pelobacter.6048 - ppd.1097 ppd:Ppro_1071 thiamine biosynthesis protein OC.658493 Bacteria.396662 Proteobacteria.180481 Deltaproteobacteria.10583 Anaeromyxobacter.797 Anaeromyxobacter_dehalogenans.1736 ade.4023 ade:Adeh_4045 thiamine biosynthesis protein OC.658493 Bacteria.396662 Proteobacteria.180481 Deltaproteobacteria.10583 Anaeromyxobacter.797 Anaeromyxobacter_dehalogenans.1736 acp.4118 acp:A2cp1_4188 thiamine biosynthesis protein OC.658493 Bacteria.396662 Proteobacteria.180481 Deltaproteobacteria.10583 Anaeromyxobacter.797 Anaeromyxobacter_sp_.1257 afw.436 afw:Anae109_0384 thiamine biosynthesis protein OC.658493 Bacteria.396662 Proteobacteria.180481 Deltaproteobacteria.10583 Anaeromyxobacter.797 Anaeromyxobacter_sp_.7649 ank.4101 ank:AnaeK_4161 thiamine biosynthesis protein OC.658493 Bacteria.396662 Proteobacteria.180481 Deltaproteobacteria.10583 - - vin.1444 vin:AKJ08_1459 tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase OC.658493 Bacteria.396662 Proteobacteria.180481 Alphaproteobacteria.322034 - - mgm.2595 mgm:Mmc1_3145 conserved hypothetical protein