# OC Root 2nd 3rd 4th 5th PC Gene/Definition OC.88594 Archaea.36751 Thaumarchaeota.2288 Nitrosopumilus.676 - nir.496 nir:NSED_02465 uroporphyrin-III C-methyltransferase; K02303 uroporphyrin-III C-methyltransferase [EC:2.1.1.107] OC.88594 Archaea.36751 Thaumarchaeota.2288 Nitrosopumilus.676 - nid.1766 nid:NPIRD3C_1789 Uroporphyrin-III C-methyltransferase; K02303 uroporphyrin-III C-methyltransferase [EC:2.1.1.107] OC.88594 Archaea.36751 Thaumarchaeota.2288 Nitrosopumilus.676 - nin.1656 nin:NADRNF5_1696 Uroporphyrin-III C-methyltransferase; K02303 uroporphyrin-III C-methyltransferase [EC:2.1.1.107] OC.88594 Archaea.36751 Thaumarchaeota.2288 Nitrosopumilus.4075 - nmr.496 nmr:Nmar_0492 uroporphyrin-III C-methyltransferase; K02303 uroporphyrin-III C-methyltransferase [EC:2.1.1.107] OC.88594 Archaea.36751 Thaumarchaeota.2288 - - nkr.480 nkr:NKOR_02530 uroporphyrin-III C-methyltransferase; K02303 uroporphyrin-III C-methyltransferase [EC:2.1.1.107] OC.88594 Archaea.36751 Thaumarchaeota.2288 - - nct.1163 nct:NMSP_1184 cobA_2; Uroporphyrinogen-III C-methyltransferase; K02303 uroporphyrin-III C-methyltransferase [EC:2.1.1.107] OC.88594 Archaea.36751 Thaumarchaeota.2288 - - csy.1201 csy:CENSYa_1355 uroporphyrinogen-III methylase; K02303 uroporphyrin-III C-methyltransferase [EC:2.1.1.107] OC.88594 Archaea.36751 Thaumarchaeota.2288 Nitrososphaera.33 - nga.2440 nga:Ngar_c26110 cysG; uroporphyrinogen-III C-methyltransferase; K02303 uroporphyrin-III C-methyltransferase [EC:2.1.1.107] OC.88594 Archaea.36751 Thaumarchaeota.2288 Nitrososphaera.33 - nvn.2645 nvn:NVIE_027750 uroporphyrinogen-III C-methyltransferase; K02303 uroporphyrin-III C-methyltransferase [EC:2.1.1.107] OC.88594 Archaea.36751 Thaumarchaeota.2288 Nitrososphaera.33 - nev.1026 nev:NTE_01011 uroporphyrin-III C-methyltransferase; K02303 uroporphyrin-III C-methyltransferase [EC:2.1.1.107] OC.88594 Archaea.36751 Thaumarchaeota.2288 - - taa.1250 taa:NMY3_01269 sumT; Uroporphyrinogen-III C-methyltransferase; K02303 uroporphyrin-III C-methyltransferase [EC:2.1.1.107] OC.88594 Archaea.36751 Thaumarchaeota.2288 - - tah.664 tah:SU86_003670 uroporphyrin-III methyltransferase; K02303 uroporphyrin-III C-methyltransferase [EC:2.1.1.107] OC.88594 Archaea.36751 Thaumarchaeota.2288 - - ndv.505 ndv:NDEV_0445 Uroporphyrinogen-III methylase; K02303 uroporphyrin-III C-methyltransferase [EC:2.1.1.107] OC.88594 Archaea.36751 Thaumarchaeota.2289 - - ncv.247 ncv:NCAV_0222 Uroporphyrinogen-III C-methyltransferase; K02303 uroporphyrin-III C-methyltransferase [EC:2.1.1.107] OC.88595 Archaea.7696 Crenarchaeota.12931 - - hbu.803 hbu:Hbut_0835 Uroporphyrin-III C-methyltransferase; K02303 uroporphyrin-III C-methyltransferase [EC:2.1.1.107] OC.88595 Archaea.7696 Crenarchaeota.12931 - - pfm.1329 pfm:Pyrfu_1382 uroporphyrin-III C-methyltransferase; K02303 uroporphyrin-III C-methyltransferase [EC:2.1.1.107] OC.88595 Archaea.7696 Crenarchaeota.12931 - - pdl.1542 pdl:Pyrde_1565 Uroporphyrinogen-III methyltransferase; K02303 uroporphyrin-III C-methyltransferase [EC:2.1.1.107] OC.88596 Archaea.28755 Euryarchaeota.32495 Methanosaeta.1421 - mtp.1095 mtp:Mthe_1124 uroporphyrinogen-III synthase / uroporphyrinogen-III C-methyltransferase; K13542 uroporphyrinogen III methyltransferase / synthase [EC:2.1.1.107 4.2.1.75] OC.88596 Archaea.28755 Euryarchaeota.32495 Methanosaeta.1421 - mcj.787 mcj:MCON_0901 cobA; uroporphyrinogen III synthase/methyltransferase; K13542 uroporphyrinogen III methyltransferase / synthase [EC:2.1.1.107 4.2.1.75] OC.88596 Archaea.28755 Euryarchaeota.32495 Methanosaeta.1421 - mhi.1237 mhi:Mhar_1275 Uroporphyrinogen III synthase/methyltransferase; K13542 uroporphyrinogen III methyltransferase / synthase [EC:2.1.1.107 4.2.1.75] OC.88597 Archaea.54772 Euryarchaeota.38176 - - mer.1513 mer:MMINT_17270 uroporphyrinogen-III C-methyltransferase; K02303 uroporphyrin-III C-methyltransferase [EC:2.1.1.107] OC.88598 Archaea.35923 Euryarchaeota.9873 Methanocella.1453 - mpd.2792 mpd:MCP_2924 cobA; uroporphyrin-III C-methyltransferase; K02303 uroporphyrin-III C-methyltransferase [EC:2.1.1.107] OC.88598 Archaea.35923 Euryarchaeota.9873 Methanocella.1453 - mez.362 mez:Mtc_0320 cobA; uroporphyrin-III C-methyltransferase; K02303 uroporphyrin-III C-methyltransferase [EC:2.1.1.107] OC.88598 Archaea.35923 Euryarchaeota.9873 Methanocella.1453 - rci.2469 rci:RCIX915 cysG; uroporphyrin-III C-methyltransferase; K02303 uroporphyrin-III C-methyltransferase [EC:2.1.1.107] OC.88598 Archaea.35923 Euryarchaeota.9874 Methanosarcina.4051 Methanosarcina_sp_.1093 mef.2074 mef:MSWH1_2150 Uroporphyrinogen-III methyltransferase; K02303 uroporphyrin-III C-methyltransferase [EC:2.1.1.107] OC.88598 Archaea.35923 Euryarchaeota.9874 Methanosarcina.4051 Methanosarcina_sp_.1093 meq.2847 meq:MSWHS_2947 Uroporphyrinogen-III methyltransferase; K02303 uroporphyrin-III C-methyltransferase [EC:2.1.1.107] OC.88598 Archaea.35923 Euryarchaeota.9874 Methanosarcina.4051 Methanosarcina_sp_.5796 mek.2640 mek:MSKOL_2658 Uroporphyrinogen-III methyltransferase; K02303 uroporphyrin-III C-methyltransferase [EC:2.1.1.107] OC.88598 Archaea.35923 Euryarchaeota.9874 Methanosarcina.4051 Methanosarcina_sp_.8879 metm.2194 metm:MSMTP_2248 Uroporphyrinogen-III methyltransferase; K02303 uroporphyrin-III C-methyltransferase [EC:2.1.1.107] OC.88598 Archaea.35923 Euryarchaeota.9874 Methanosarcina.4051 - mac.2815 mac:MA_3033 uroporphyrin-III C-methyltransferase; K02303 uroporphyrin-III C-methyltransferase [EC:2.1.1.107] OC.88598 Archaea.35923 Euryarchaeota.9874 Methanosarcina.4051 Methanosarcina_barkeri.830 mba.1738 mba:Mbar_A1791 uroporphyrinogen-III C-methyltransferase; K02303 uroporphyrin-III C-methyltransferase [EC:2.1.1.107] OC.88598 Archaea.35923 Euryarchaeota.9874 Methanosarcina.4051 Methanosarcina_barkeri.830 mby.671 mby:MSBRM_0677 Uroporphyrinogen-III methyltransferase; K02303 uroporphyrin-III C-methyltransferase [EC:2.1.1.107] OC.88598 Archaea.35923 Euryarchaeota.9874 Methanosarcina.4051 Methanosarcina_barkeri.830 mbw.2921 mbw:MSBRW_2945 Uroporphyrinogen-III methyltransferase; K02303 uroporphyrin-III C-methyltransferase [EC:2.1.1.107] OC.88598 Archaea.35923 Euryarchaeota.9874 Methanosarcina.4051 Methanosarcina_barkeri.830 mbar.1697 mbar:MSBR2_1699 Uroporphyrinogen-III methyltransferase; K02303 uroporphyrin-III C-methyltransferase [EC:2.1.1.107] OC.88598 Archaea.35923 Euryarchaeota.9874 Methanosarcina.4051 Methanosarcina_barkeri.5756 mbak.1694 mbak:MSBR3_1692 Uroporphyrinogen-III methyltransferase; K02303 uroporphyrin-III C-methyltransferase [EC:2.1.1.107] OC.88598 Archaea.35923 Euryarchaeota.9874 Methanosarcina.4051 Methanosarcina_mazei.2344 mma.339 mma:MM_0307 Uroporphyrin-III C-methyltransferase; K02303 uroporphyrin-III C-methyltransferase [EC:2.1.1.107] OC.88598 Archaea.35923 Euryarchaeota.9874 Methanosarcina.4051 Methanosarcina_mazei.2344 mmaz.306 mmaz:MmTuc01_0314 Uroporphyrinogen-III methyltransferase; K02303 uroporphyrin-III C-methyltransferase [EC:2.1.1.107] OC.88598 Archaea.35923 Euryarchaeota.9874 Methanosarcina.4051 Methanosarcina_mazei.2344 mmj.1004 mmj:MSMAS_0993 Uroporphyrinogen-III methyltransferase; K02303 uroporphyrin-III C-methyltransferase [EC:2.1.1.107] OC.88598 Archaea.35923 Euryarchaeota.9874 Methanosarcina.4051 Methanosarcina_mazei.2344 mmac.2277 mmac:MSMAC_2352 Uroporphyrinogen-III methyltransferase; K02303 uroporphyrin-III C-methyltransferase [EC:2.1.1.107] OC.88598 Archaea.35923 Euryarchaeota.9874 Methanosarcina.4051 - mvc.2625 mvc:MSVAZ_2653 Uroporphyrinogen-III methyltransferase; K02303 uroporphyrin-III C-methyltransferase [EC:2.1.1.107] OC.88598 Archaea.35923 Euryarchaeota.9874 Methanosarcina.4051 - mls.1290 mls:MSLAZ_1288 Uroporphyrinogen-III methyltransferase; K02303 uroporphyrin-III C-methyltransferase [EC:2.1.1.107] OC.88598 Archaea.35923 Euryarchaeota.9874 Methanosarcina.4051 Methanosarcina_siciliae.1594 msj.2822 msj:MSSAC_3005 Uroporphyrinogen-III methyltransferase; K02303 uroporphyrin-III C-methyltransferase [EC:2.1.1.107] OC.88598 Archaea.35923 Euryarchaeota.9874 Methanosarcina.4051 Methanosarcina_siciliae.1594 msz.2623 msz:MSSIH_2644 Uroporphyrinogen-III methyltransferase; K02303 uroporphyrin-III C-methyltransferase [EC:2.1.1.107] OC.88598 Archaea.35923 Euryarchaeota.9874 Methanosarcina.4051 Methanosarcina_siciliae.1594 msw.2644 msw:MSSIT_2683 Uroporphyrinogen-III methyltransferase; K02303 uroporphyrin-III C-methyltransferase [EC:2.1.1.107] OC.88598 Archaea.35923 Euryarchaeota.9874 Methanosarcina.4051 Methanosarcina_thermophila.2159 mthe.756 mthe:MSTHC_0747 Uroporphyrinogen-III methyltransferase; K02303 uroporphyrin-III C-methyltransferase [EC:2.1.1.107] OC.88598 Archaea.35923 Euryarchaeota.9874 Methanosarcina.4051 Methanosarcina_thermophila.2159 mthr.2517 mthr:MSTHT_2536 Uroporphyrinogen-III methyltransferase; K02303 uroporphyrin-III C-methyltransferase [EC:2.1.1.107] OC.88598 Archaea.35923 Euryarchaeota.9874 Methanosarcina.4051 - mhor.1201 mhor:MSHOH_1183 Uroporphyrinogen-III methyltransferase; K02303 uroporphyrin-III C-methyltransferase [EC:2.1.1.107] OC.88598 Archaea.35923 Euryarchaeota.9874 Methanococcoides.1551 - mbu.968 mbu:Mbur_1105 cysGA; Uroporphyrinogen-III C-methyltransferase; K02303 uroporphyrin-III C-methyltransferase [EC:2.1.1.107] OC.88598 Archaea.35923 Euryarchaeota.9874 Methanococcoides.1551 - mmet.1566 mmet:MCMEM_1580 Uroporphyrinogen-III methyltransferase; K02303 uroporphyrin-III C-methyltransferase [EC:2.1.1.107] OC.88598 Archaea.35923 Euryarchaeota.9874 Methanohalophilus.361 - mmh.548 mmh:Mmah_0559 uroporphyrinogen-III C-methyltransferase; K02303 uroporphyrin-III C-methyltransferase [EC:2.1.1.107] OC.88598 Archaea.35923 Euryarchaeota.9874 Methanohalophilus.361 - mhaz.134 mhaz:BHR79_00615 uroporphyrinogen-III C-methyltransferase; K02303 uroporphyrin-III C-methyltransferase [EC:2.1.1.107] OC.88598 Archaea.35923 Euryarchaeota.9874 - - mev.395 mev:Metev_0303 uroporphyrin-III C-methyltransferase; K02303 uroporphyrin-III C-methyltransferase [EC:2.1.1.107] OC.88598 Archaea.35923 Euryarchaeota.9874 - - mzh.1274 mzh:Mzhil_1356 uroporphyrin-III C-methyltransferase; K02303 uroporphyrin-III C-methyltransferase [EC:2.1.1.107] OC.88598 Archaea.35923 Euryarchaeota.9874 - - mpy.2542 mpy:Mpsy_2708 uroporphyrinogen-III C-methyltransferase; K02303 uroporphyrin-III C-methyltransferase [EC:2.1.1.107] OC.88598 Archaea.35923 Euryarchaeota.9874 - - mhz.1724 mhz:Metho_1862 uroporphyrin-III C-methyltransferase; K02303 uroporphyrin-III C-methyltransferase [EC:2.1.1.107] OC.88598 Archaea.35923 Euryarchaeota.9874 - - mhu.2243 mhu:Mhun_2558 uroporphyrinogen-III C-methyltransferase; K02303 uroporphyrin-III C-methyltransferase [EC:2.1.1.107] OC.88598 Archaea.35923 Euryarchaeota.9874 Methanoculleus.918 - mem.968 mem:Memar_0984 uroporphyrinogen-III C-methyltransferase; K02303 uroporphyrin-III C-methyltransferase [EC:2.1.1.107] OC.88598 Archaea.35923 Euryarchaeota.9874 Methanoculleus.918 - mbg.1819 mbg:BN140_1915 hemX; uroporphyrin-III C-methyltransferase; K02303 uroporphyrin-III C-methyltransferase [EC:2.1.1.107] OC.88598 Archaea.35923 Euryarchaeota.9874 Methanoculleus.918 - mema.2405 mema:MMAB1_2470 cobA; Uroporphyrinogen-III C-methyltransferase; K02303 uroporphyrin-III C-methyltransferase [EC:2.1.1.107] OC.88598 Archaea.35923 Euryarchaeota.9874 - - mpi.1456 mpi:Mpet_1525 uroporphyrin-III C-methyltransferase; K02303 uroporphyrin-III C-methyltransferase [EC:2.1.1.107] OC.88598 Archaea.35923 Euryarchaeota.9874 Methanoregula.131 - mbn.1217 mbn:Mboo_1233 uroporphyrin-III C-methyltransferase; K02303 uroporphyrin-III C-methyltransferase [EC:2.1.1.107] OC.88598 Archaea.35923 Euryarchaeota.9874 Methanoregula.131 - mfo.1726 mfo:Metfor_1836 uroporphyrin-III C-methyltransferase; K02303 uroporphyrin-III C-methyltransferase [EC:2.1.1.107] OC.88598 Archaea.35923 Euryarchaeota.9874 - - mpl.1576 mpl:Mpal_1724 uroporphyrin-III C-methyltransferase; K02303 uroporphyrin-III C-methyltransferase [EC:2.1.1.107] OC.88599 Archaea.100544 - - - loki.2637 loki:Lokiarch_29900 sumT_1; Uroporphyrinogen-III C-methyltransferase; K02303 uroporphyrin-III C-methyltransferase [EC:2.1.1.107]