KofamKOALA - KEGG Orthology Search
K number assignment based on KO-dependent scoring criteria
KofamKOALA assigns K numbers to the user's sequence data by HMMER/HMMSEARCH against KOfam (a customized HMM database of KEGG Orthologs (KOs)). K number assignments with scores above the predefined thresholds for individual KOs are more reliable than other proposed assignments. Such high score assignments are highlighted with asterisks '*' in the output. The K number assignments facilitate the interpretation of the annotation results by linking the user's sequence data to the KEGG pathways and EC numbers.
Enter FASTA Sequences
or upload a sequence file
KEGG release 90.0
KEGG release 89.1
KOfam - HMM profiles for KEGG/KO with predefined score thresholds (
KofamScan - Software to search KOfam (
Aramaki T., Blanc-Mathieu R., Endo H., Ohkubo K., Kanehisa M., Goto S., Ogata H. KofamKOALA: KEGG ortholog assignment based on profile HMM and adaptive score threshold.
Last updated: April 9, 2019