PCIDB

KNApSAcK Metabolite C00011153

Metabolite

KNApSAcK Entry

id C00011153
Name Gallogen / Ellagic acid / Elagostasine / Alizarin yellow
CAS RN 476-66-4
Standard InChI InChI=1S/C14H6O8/c15-5-1-3-7-8-4(14(20)22-11(7)9(5)17)2-6(16)10(18)12(8)21-13(3)19/h1-2,15-18H
Standard InChI (Main Layer) InChI=1S/C14H6O8/c15-5-1-3-7-8-4(14(20)22-11(7)9(5)17)2-6(16)10(18)12(8)21-13(3)19/h1-2,15-18H

Cluster

Phytochemical cluster No. 81
KCF-S cluster No. 2068

Link

ChEMBL

By standard InChI CHEMBL6246
By standard InChI Main Layer CHEMBL6246

KEGG

By LinkDB C10788

CTD

By CAS RN D004610

Human Protein / Gene in interaction

104 ChEMBL Protein in interactions

accession description class description compound assay ID (# of activities) # of diseases
(OMIM / KEGG)
P04637 Cellular tumor antigen p53 Transcription Factor CHEMBL6246 CHEMBL1613992 (2)
7 / 44
Q07820 Induced myeloid leukemia cell differentiation protein Mcl-1 Other cytosolic protein CHEMBL6246 CHEMBL1614529 (1)
0 / 0
Q9UIF8 Bromodomain adjacent to zinc finger domain protein 2B Unclassified protein CHEMBL6246 CHEMBL1738312 (1)
0 / 0
P49798 Regulator of G-protein signaling 4 Unclassified protein CHEMBL6246 CHEMBL1794499 (1)
2 / 0
P08069 Insulin-like growth factor 1 receptor TK tyrosine-protein kinase INSR subfamily CHEMBL6246 CHEMBL1961284 (1)
1 / 3
P06746 DNA polymerase beta Enzyme CHEMBL6246 CHEMBL1614079 (1)
0 / 0
P10253 Lysosomal alpha-glucosidase Hydrolase CHEMBL6246 CHEMBL1614076 (1)
1 / 1
Q9Y2D0 Carbonic anhydrase 5B, mitochondrial Lyase CHEMBL6246 CHEMBL1074270 (1)
0 / 0
P35218 Carbonic anhydrase 5A, mitochondrial Lyase CHEMBL6246 CHEMBL1074269 (1)
0 / 0
P43166 Carbonic anhydrase 7 Lyase CHEMBL6246 CHEMBL1074272 (1) CHEMBL2341285 (1)
0 / 0
P04406 Glyceraldehyde-3-phosphate dehydrogenase Enzyme CHEMBL6246 CHEMBL1613955 (1)
0 / 0
Q13526 Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 Enzyme CHEMBL6246 CHEMBL1794585 (1)
0 / 0
Q8N1Q1 Carbonic anhydrase 13 Lyase CHEMBL6246 CHEMBL2341282 (1)
0 / 0
O14965 Aurora kinase A Aur CHEMBL6246 CHEMBL1961275 (1)
0 / 0
Q13315 Serine-protein kinase ATM Atypical serine/threonine protein kinase PIKK subfamily CHEMBL6246 CHEMBL1614153 (1)
1 / 4
O75604 Ubiquitin carboxyl-terminal hydrolase 2 Enzyme CHEMBL6246 CHEMBL1614474 (1)
0 / 0
P02545 Prelamin-A/C Unclassified protein CHEMBL6246 CHEMBL1614544 (1)
11 / 10
P10828 Thyroid hormone receptor beta NR1A2 CHEMBL6246 CHEMBL1613776 (2)
3 / 1
P68400 Casein kinase II subunit alpha Ck2 CHEMBL6246 CHEMBL974405 (1)
0 / 0
P00918 Carbonic anhydrase 2 Lyase CHEMBL6246 CHEMBL1074266 (1) CHEMBL2341286 (1)
1 / 2
P51452 Dual specificity protein phosphatase 3 Ser_Thr_Tyr CHEMBL6246 CHEMBL1613889 (1) CHEMBL1614401 (1)
0 / 0
P11712 Cytochrome P450 2C9 Cytochrome P450 2C9 CHEMBL6246 CHEMBL1614027 (1)
0 / 1
O00444 Serine/threonine-protein kinase PLK4 PLK serine/threonine protein kinase subfamily CHEMBL6246 CHEMBL1961235 (1)
0 / 0
P11802 Cyclin-dependent kinase 4 CMGC serine/threonine protein kinase family CHEMBL6246 CHEMBL1961279 (1)
1 / 3
P24385 G1/S-specific cyclin-D1 Other cytosolic protein CHEMBL6246 CHEMBL1961279 (1)
1 / 10
P54132 Bloom syndrome protein Enzyme CHEMBL6246 CHEMBL1614067 (3)
1 / 2
Q9HC97 G-protein coupled receptor 35 Kynurenic acid receptor CHEMBL6246 CHEMBL2039370 (1) CHEMBL2039371 (1)
CHEMBL2039375 (1) CHEMBL2039376 (1)
CHEMBL2039377 (1) CHEMBL2039381 (1)
0 / 0
Q9NR56 Muscleblind-like protein 1 Unclassified protein CHEMBL6246 CHEMBL1614166 (1)
1 / 0
P00533 Epidermal growth factor receptor TK tyrosine-protein kinase EGFR subfamily CHEMBL6246 CHEMBL1961280 (1)
1 / 11
P11473 Vitamin D3 receptor NR1I1 CHEMBL6246 CHEMBL1794311 (1)
2 / 3
P23280 Carbonic anhydrase 6 Lyase CHEMBL6246 CHEMBL1074271 (1)
0 / 0
O15296 Arachidonate 15-lipoxygenase B Enzyme CHEMBL6246 CHEMBL1613800 (2)
0 / 0
Q9ULX7 Carbonic anhydrase 14 Lyase CHEMBL6246 CHEMBL1074276 (1)
0 / 0
P68871 Hemoglobin subunit beta Secreted protein CHEMBL6246 CHEMBL1613976 (1)
4 / 4
O43570 Carbonic anhydrase 12 Lyase CHEMBL6246 CHEMBL1074274 (1) CHEMBL2341283 (1)
1 / 2
P36888 Receptor-type tyrosine-protein kinase FLT3 Pdgfr CHEMBL6246 CHEMBL861019 (1)
1 / 1
P54760 Ephrin type-B receptor 4 Eph CHEMBL6246 CHEMBL1961281 (1)
0 / 0
P39748 Flap endonuclease 1 Enzyme CHEMBL6246 CHEMBL1794486 (2)
0 / 0
Q92830 Histone acetyltransferase KAT2A Enzyme CHEMBL6246 CHEMBL1738606 (1)
0 / 0
P84022 Mothers against decapentaplegic homolog 3 Unclassified protein CHEMBL6246 CHEMBL1614270 (1)
2 / 0
O75496 Geminin Unclassified protein CHEMBL6246 CHEMBL2114843 (1) CHEMBL2114780 (1)
0 / 0
P15121 Aldose reductase Enzyme CHEMBL6246 CHEMBL1942674 (1)
0 / 0
P00915 Carbonic anhydrase 1 Lyase CHEMBL6246 CHEMBL1074265 (1) CHEMBL2341287 (1)
0 / 0
P49841 Glycogen synthase kinase-3 beta Gsk CHEMBL6246 CHEMBL861009 (1)
0 / 0
Q05397 Focal adhesion kinase 1 Fak CHEMBL6246 CHEMBL1961283 (1)
0 / 0
P09211 Glutathione S-transferase P Enzyme CHEMBL6246 CHEMBL1694674 (1)
0 / 2
Q02763 Angiopoietin-1 receptor Tie CHEMBL6246 CHEMBL1961236 (1)
1 / 1
P15056 Serine/threonine-protein kinase B-raf Raf CHEMBL6246 CHEMBL1961277 (1)
6 / 3
P08107 Heat shock 70 kDa protein 1A/1B Unclassified protein CHEMBL6246 CHEMBL1614054 (1) CHEMBL1614297 (1)
CHEMBL1613848 (1)
0 / 0
Q9Y253 DNA polymerase eta Enzyme CHEMBL6246 CHEMBL1794569 (1)
1 / 1
O60285 NUAK family SNF1-like kinase 1 CAMK serine/threonine protein kinase NUAK subfamily CHEMBL6246 CHEMBL1961274 (1)
0 / 0
Q03164 Histone-lysine N-methyltransferase 2A Enzyme CHEMBL6246 CHEMBL1614319 (1) CHEMBL1614410 (1)
CHEMBL1613988 (1)
1 / 3
Q4U2R8 Solute carrier family 22 member 6 Antiporter CHEMBL6246 CHEMBL2077040 (1) CHEMBL2077163 (1)
0 / 0
P83916 Chromobox protein homolog 1 Unclassified protein CHEMBL6246 CHEMBL1794401 (1)
0 / 0
P11021 78 kDa glucose-regulated protein Unclassified protein CHEMBL6246 CHEMBL1963893 (1)
0 / 0
O94782 Ubiquitin carboxyl-terminal hydrolase 1 Enzyme CHEMBL6246 CHEMBL1794467 (1)
0 / 0
P06213 Insulin receptor TK tyrosine-protein kinase INSR subfamily CHEMBL6246 CHEMBL1961231 (1)
5 / 4
P04626 Receptor tyrosine-protein kinase erbB-2 TK tyrosine-protein kinase EGFR subfamily CHEMBL6246 CHEMBL1961282 (1)
5 / 10
P09619 Platelet-derived growth factor receptor beta Pdgfr CHEMBL6246 CHEMBL1961233 (1)
5 / 1
P12931 Proto-oncogene tyrosine-protein kinase Src Src CHEMBL6246 CHEMBL816866 (1) CHEMBL1960851 (1)
0 / 0
Q96GD4 Aurora kinase B Aur CHEMBL6246 CHEMBL1961276 (1)
0 / 0
P35968 Vascular endothelial growth factor receptor 2 Vegfr CHEMBL6246 CHEMBL1961229 (1)
1 / 0
P08581 Hepatocyte growth factor receptor TK tyrosine-protein kinase MET subfamily CHEMBL6246 CHEMBL1961232 (1)
2 / 3
P28482 Mitogen-activated protein kinase 1 Erk CHEMBL6246 CHEMBL1613808 (1)
0 / 0
P35916 Vascular endothelial growth factor receptor 3 Vegfr CHEMBL6246 CHEMBL1961230 (1)
2 / 1
P00390 Glutathione reductase, mitochondrial Oxidoreductase CHEMBL6246 CHEMBL1694676 (1) CHEMBL1695820 (1)
CHEMBL1695821 (1)
0 / 0
Q16790 Carbonic anhydrase 9 Lyase CHEMBL6246 CHEMBL1074273 (1) CHEMBL2341284 (1)
0 / 1
P41279 Mitogen-activated protein kinase kinase kinase 8 Ste11 CHEMBL6246 CHEMBL1961237 (1)
0 / 0
Q99714 3-hydroxyacyl-CoA dehydrogenase type-2 Enzyme CHEMBL6246 CHEMBL1613910 (2) CHEMBL1614227 (1)
3 / 3
P15428 15-hydroxyprostaglandin dehydrogenase [NAD(+)] Enzyme CHEMBL6246 CHEMBL1614038 (3)
2 / 2
P12821 Angiotensin-converting enzyme M2 CHEMBL6246 CHEMBL1015636 (1)
4 / 2
P53350 Serine/threonine-protein kinase PLK1 PLK serine/threonine protein kinase subfamily CHEMBL6246 CHEMBL1961234 (1)
0 / 0
Q02880 DNA topoisomerase 2-beta Isomerase CHEMBL6246 CHEMBL687375 (1)
0 / 0
P16050 Arachidonate 15-lipoxygenase Enzyme CHEMBL6246 CHEMBL1614240 (1)
0 / 0
P31749 RAC-alpha serine/threonine-protein kinase Akt CHEMBL6246 CHEMBL1961273 (1)
4 / 1
P33261 Cytochrome P450 2C19 Cytochrome P450 2C19 CHEMBL6246 CHEMBL1613777 (1)
1 / 1
P07949 Proto-oncogene tyrosine-protein kinase receptor Ret Ret CHEMBL6246 CHEMBL861018 (1)
9 / 5
Q9UNA4 DNA polymerase iota Enzyme CHEMBL6246 CHEMBL1794483 (2)
0 / 0
O75164 Lysine-specific demethylase 4A Enzyme CHEMBL6246 CHEMBL1737991 (1)
0 / 0
P27695 DNA-(apurinic or apyrimidinic site) lyase Enzyme CHEMBL6246 CHEMBL1614466 (1) CHEMBL1614211 (2)
0 / 0
P10636 Microtubule-associated protein tau Unclassified protein CHEMBL6246 CHEMBL1614250 (3) CHEMBL1614421 (3)
CHEMBL1614502 (2)
4 / 3
P07451 Carbonic anhydrase 3 Lyase CHEMBL6246 CHEMBL1074267 (1)
0 / 0
Q13627 Dual specificity tyrosine-phosphorylation-regulated kinase 1A CMGC dual-specificity kinase DYRK1 CHEMBL6246 CHEMBL861010 (1)
1 / 0
P22748 Carbonic anhydrase 4 Lyase CHEMBL6246 CHEMBL1074268 (1)
1 / 1
Q9UBT6 DNA polymerase kappa Enzyme CHEMBL6246 CHEMBL1794536 (3)
0 / 0
P11142 Heat shock cognate 71 kDa protein Unclassified protein CHEMBL6246 CHEMBL1613796 (1) CHEMBL1614143 (1)
0 / 0
B2RXH2 Lysine-specific demethylase 4E Enzyme CHEMBL6246 CHEMBL1613914 (3)
0 / 0
P46063 ATP-dependent DNA helicase Q1 Enzyme CHEMBL6246 CHEMBL1613829 (3) CHEMBL1613928 (1)
0 / 0
Q96KQ7 Histone-lysine N-methyltransferase EHMT2 Enzyme CHEMBL6246 CHEMBL1738442 (1)
0 / 0
Q9NUW8 Tyrosyl-DNA phosphodiesterase 1 Enzyme CHEMBL6246 CHEMBL1614364 (3) CHEMBL1738394 (1)
1 / 1
O75874 Isocitrate dehydrogenase [NADP] cytoplasmic Enzyme CHEMBL6246 CHEMBL2354311 (1)
1 / 0
O00255 Menin Unclassified protein CHEMBL6246 CHEMBL1614319 (1) CHEMBL1613988 (1)
2 / 5
Q13951 Core-binding factor subunit beta Unclassified protein CHEMBL6246 CHEMBL1738090 (1) CHEMBL1737904 (1)
0 / 1
Q01196 Runt-related transcription factor 1 Unclassified protein CHEMBL6246 CHEMBL1738090 (1) CHEMBL1737904 (1)
1 / 6
Q9NSA0 Solute carrier family 22 member 11 Transporter CHEMBL6246 CHEMBL2075394 (1) CHEMBL2077721 (1)
0 / 0
P20248 Cyclin-A2 Other cytosolic protein CHEMBL6246 CHEMBL1961278 (1)
0 / 0
P78396 Cyclin-A1 Other cytosolic protein CHEMBL6246 CHEMBL1961278 (1)
0 / 0
P24941 Cyclin-dependent kinase 2 Cdc2 CHEMBL6246 CHEMBL1961278 (1)
0 / 0
P22694 cAMP-dependent protein kinase catalytic subunit beta Pka CHEMBL6246 CHEMBL766844 (1) CHEMBL861008 (1)
0 / 0
P17612 cAMP-dependent protein kinase catalytic subunit alpha Pka CHEMBL6246 CHEMBL766844 (1) CHEMBL861008 (1)
0 / 0
P22612 cAMP-dependent protein kinase catalytic subunit gamma Pka CHEMBL6246 CHEMBL766844 (1) CHEMBL861008 (1)
0 / 0
Q9UM73 ALK tyrosine kinase receptor TKL serine/threonine protein kinase STKR type 1 subfamily CHEMBL6246 CHEMBL861015 (1) CHEMBL861020 (1)
CHEMBL861022 (1) CHEMBL861023 (1)
1 / 1
P06748 Nucleophosmin Other nuclear protein CHEMBL6246 CHEMBL861015 (1) CHEMBL861020 (1)
CHEMBL861022 (1) CHEMBL861023 (1)
0 / 0
O94925 Glutaminase kidney isoform, mitochondrial Enzyme CHEMBL6246 CHEMBL2114738 (1)
0 / 0

CTD interaction (90)

compound gene gene name gene description interaction interaction type form reference
pmid
D004610 55 ACPP
5'-NT
ACP-3
ACP3
PAP
acid phosphatase, prostate (EC:3.1.3.2 3.1.3.5) Ellagic Acid results in increased expression of ACPP mRNA increases expression
mRNA 12002526
D004610 213 ALB
PRO0883
PRO0903
PRO1341
albumin ALB protein promotes the reaction [Ellagic Acid results in increased activity of F12 protein] increases activity
/ increases reaction
protein 6343536
D004610 317 APAF1
APAF-1
CED4
apoptotic peptidase activating factor 1 Ellagic Acid results in decreased expression of APAF1 mRNA decreases expression
mRNA 12002526
D004610 429 ASCL1
ASH1
HASH1
MASH1
bHLHa46
achaete-scute family bHLH transcription factor 1 Ellagic Acid results in increased expression of ASCL1 mRNA increases expression
mRNA 12002526
D004610 440 ASNS
TS11
asparagine synthetase (glutamine-hydrolyzing) (EC:6.3.5.4) Ellagic Acid results in increased expression of ASNS mRNA increases expression
mRNA 12002526
D004610 467 ATF3
activating transcription factor 3 Ellagic Acid results in increased expression of ATF3 mRNA increases expression
mRNA 12002526
D004610 9474 ATG5
APG5
APG5-LIKE
APG5L
ASP
hAPG5
autophagy related 5 Ellagic Acid results in increased expression of ATG5 mRNA increases expression
mRNA 12002526
D004610 596 BCL2
Bcl-2
PPP1R50
B-cell CLL/lymphoma 2 Ellagic Acid results in increased expression of BCL2 protein increases expression
protein 22386815
D004610 654 BMP6
VGR
VGR1
bone morphogenetic protein 6 Ellagic Acid results in decreased expression of BMP6 mRNA decreases expression
mRNA 12002526
D004610 2972 BRF1
BRF
BRF-1
GTF3B
TAF3B2
TAF3C
TAFIII90
TF3B90
TFIIIB90
hBRF
BRF1, RNA polymerase III transcription initiation factor 90 kDa subunit Ellagic Acid results in decreased expression of BRF1 mRNA decreases expression
mRNA 12002526
D004610 811 CALR
CRT
RO
SSA
cC1qR
calreticulin Ellagic Acid results in decreased expression of CALR mRNA decreases expression
mRNA 12002526
D004610 836 CASP3
CPP32
CPP32B
SCA-1
caspase 3, apoptosis-related cysteine peptidase (EC:3.4.22.56) Ellagic Acid results in decreased activity of CASP3 protein decreases activity
protein 22386815
D004610 836 CASP3
CPP32
CPP32B
SCA-1
caspase 3, apoptosis-related cysteine peptidase (EC:3.4.22.56) Ellagic Acid results in decreased expression of CASP3 mRNA decreases expression
mRNA 12002526
D004610 836 CASP3
CPP32
CPP32B
SCA-1
caspase 3, apoptosis-related cysteine peptidase (EC:3.4.22.56) Ellagic Acid results in increased expression of CASP3 mRNA increases expression
mRNA 12002526
D004610 6347 CCL2
GDCF-2
HC11
HSMCR30
MCAF
MCP-1
MCP1
SCYA2
SMC-CF
chemokine (C-C motif) ligand 2 Ellagic Acid results in decreased secretion of CCL2 protein decreases secretion
protein 20816778
D004610 929 CD14
CD14 molecule Ellagic Acid results in decreased expression of CD14 mRNA decreases expression
mRNA 20816778
D004610 1543 CYP1A1
AHH
AHRR
CP11
CYP1
P1-450
P450-C
P450DX
cytochrome P450, family 1, subfamily A, polypeptide 1 (EC:1.14.14.1) Ellagic Acid results in decreased expression of CYP1A1 mRNA decreases expression
mRNA 20816778
D004610 1616 DAXX
BING2
DAP6
EAP1
death-domain associated protein Ellagic Acid results in decreased expression of DAXX mRNA decreases expression
mRNA 12002526
D004610 1676 DFFA
DFF-45
DFF1
ICAD
DNA fragmentation factor, 45kDa, alpha polypeptide Ellagic Acid results in decreased expression of DFFA mRNA decreases expression
mRNA 12002526
D004610 1877 E4F1
E4F
E4F transcription factor 1 Ellagic Acid results in increased expression of E4F1 mRNA increases expression
mRNA 12002526
D004610 1960 EGR3
EGR-3
PILOT
early growth response 3 Ellagic Acid results in decreased expression of EGR3 mRNA decreases expression
mRNA 12002526
D004610 2033 EP300
KAT3B
RSTS2
p300
E1A binding protein p300 (EC:2.3.1.48) Ellagic Acid results in increased expression of EP300 mRNA increases expression
mRNA 12002526
D004610 2060 EPS15
AF-1P
AF1P
MLLT5
epidermal growth factor receptor pathway substrate 15 Ellagic Acid results in increased expression of EPS15 mRNA increases expression
mRNA 12002526
D004610 2145 EZH1
KMT6B
enhancer of zeste homolog 1 (Drosophila) (EC:2.1.1.43) Ellagic Acid results in increased expression of EZH1 mRNA increases expression
mRNA 12002526
D004610 2161 F12
HAE3
HAEX
HAF
coagulation factor XII (Hageman factor) (EC:3.4.21.38) ALB protein promotes the reaction [Ellagic Acid results in increased activity of F12 protein] increases activity
/ increases reaction
protein 6343536
D004610 2161 F12
HAE3
HAEX
HAF
coagulation factor XII (Hageman factor) (EC:3.4.21.38) Ellagic Acid results in increased activity of F12 protein increases activity
protein 6343536
D004610 2260 FGFR1
BFGFR
CD331
CEK
FGFBR
FGFR-1
FLG
FLT-2
FLT2
HBGFR
HH2
HRTFDS
KAL2
N-SAM
OGD
bFGF-R-1
fibroblast growth factor receptor 1 (EC:2.7.10.1) Ellagic Acid results in decreased expression of FGFR1 mRNA decreases expression
mRNA 12002526
D004610 2316 FLNA
ABP-280
ABPX
CSBS
CVD1
FLN
FLN-A
FLN1
FMD
MNS
NHBP
OPD
OPD1
OPD2
XLVD
XMVD
filamin A, alpha Ellagic Acid results in decreased expression of FLNA mRNA decreases expression
mRNA 12002526
D004610 2822 GPLD1
GPIPLD
GPIPLDM
PIGPLD
PIGPLD1
glycosylphosphatidylinositol specific phospholipase D1 (EC:3.1.4.50) Ellagic Acid results in decreased expression of GPLD1 mRNA decreases expression
mRNA 12002526
D004610 2941 GSTA4
GSTA4-4
GTA4
glutathione S-transferase alpha 4 (EC:2.5.1.18) Ellagic Acid results in increased expression of GSTA4 mRNA increases expression
mRNA 12002526
D004610 2961 GTF2E2
FE
TF2E2
TFIIE-B
general transcription factor IIE, polypeptide 2, beta 34kDa Ellagic Acid results in increased expression of GTF2E2 mRNA increases expression
mRNA 12002526
D004610 2968 GTF2H4
P52
TFB2
TFIIH
general transcription factor IIH, polypeptide 4, 52kDa Ellagic Acid results in increased expression of GTF2H4 mRNA increases expression
mRNA 12002526
D004610 3091 HIF1A
HIF-1A
HIF-1alpha
HIF1
HIF1-ALPHA
MOP1
PASD8
bHLHe78
hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) Ellagic Acid results in decreased expression of HIF1A mRNA decreases expression
mRNA 12002526
D004610 3162 HMOX1
HMOX1D
HO-1
HSP32
bK286B10
heme oxygenase (decycling) 1 (EC:1.14.99.3) Ellagic Acid results in increased expression of HMOX1 protein increases expression
protein 22386815
D004610 9592 IER2
ETR101
immediate early response 2 Ellagic Acid results in increased expression of IER2 mRNA increases expression
mRNA 12002526
D004610 3485 IGFBP2
IBP2
IGF-BP53
insulin-like growth factor binding protein 2, 36kDa Ellagic Acid results in increased expression of IGFBP2 mRNA increases expression
mRNA 12002526
D004610 3487 IGFBP4
BP-4
HT29-IGFBP
IBP4
IGFBP-4
insulin-like growth factor binding protein 4 Ellagic Acid results in decreased expression of IGFBP4 mRNA decreases expression
mRNA 12002526
D004610 3553 IL1B
IL-1
IL1-BETA
IL1F2
interleukin 1, beta Ellagic Acid inhibits the reaction [IL1B protein results in increased secretion of IL8 protein] decreases reaction
/ increases secretion
protein 18377686
D004610 3553 IL1B
IL-1
IL1-BETA
IL1F2
interleukin 1, beta Ellagic Acid results in decreased expression of IL1B mRNA decreases expression
mRNA 20816778
D004610 3554 IL1R1
CD121A
D2S1473
IL-1R-alpha
IL1R
IL1RA
P80
interleukin 1 receptor, type I Ellagic Acid results in decreased expression of IL1R1 mRNA decreases expression
mRNA 20816778
D004610 3576 IL8
CXCL8
GCP-1
GCP1
LECT
LUCT
LYNAP
MDNCF
MONAP
NAF
NAP-1
NAP1
interleukin 8 Ellagic Acid inhibits the reaction [IL1B protein results in increased secretion of IL8 protein] decreases reaction
/ increases secretion
protein 18377686
D004610 3635 INPP5D
SHIP
SHIP-1
SHIP1
SIP-145
hp51CN
inositol polyphosphate-5-phosphatase, 145kDa (EC:3.1.3.86) Ellagic Acid results in increased expression of INPP5D mRNA increases expression
mRNA 12002526
D004610 10788 IQGAP2
IQ motif containing GTPase activating protein 2 Ellagic Acid results in increased expression of IQGAP2 mRNA increases expression
mRNA 12002526
D004610 10379 IRF9
IRF-9
ISGF3
ISGF3G
p48
interferon regulatory factor 9 Ellagic Acid results in increased expression of IRF9 mRNA increases expression
mRNA 12002526
D004610 354 KLK3
APS
KLK2A1
PSA
hK3
kallikrein-related peptidase 3 (EC:3.4.21.77) Ellagic Acid results in decreased expression of KLK3 mRNA decreases expression
mRNA 12002526
D004610 9516 LITAF
PIG7
SIMPLE
TP53I7
lipopolysaccharide-induced TNF factor Ellagic Acid results in increased expression of LITAF mRNA increases expression
mRNA 12002526
D004610 4130 MAP1A
MAP1L
MTAP1A
microtubule-associated protein 1A Ellagic Acid results in decreased expression of MAP1A mRNA decreases expression
mRNA 12002526
D004610 23531 MMD
MMA
MMD1
PAQR11
monocyte to macrophage differentiation-associated Ellagic Acid results in increased expression of MMD mRNA increases expression
mRNA 12002526
D004610 4313 MMP2
CLG4
CLG4A
MMP-II
MONA
TBE-1
matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase) (EC:3.4.24.24) Ellagic Acid results in decreased activity of and results in decreased secretion of MMP2 protein decreases activity
/ decreases secretion
protein 21573219
D004610 4313 MMP2
CLG4
CLG4A
MMP-II
MONA
TBE-1
matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase) (EC:3.4.24.24) zinc chloride inhibits the reaction [Ellagic Acid results in decreased activity of and results in decreased secretion of MMP2 protein] decreases activity
/ decreases reaction
/ decreases secretion
protein 21573219
D004610 4780 NFE2L2
NRF2
nuclear factor, erythroid 2-like 2 Ellagic Acid affects the localization of NFE2L2 protein affects localization
protein 22386815
D004610 4780 NFE2L2
NRF2
nuclear factor, erythroid 2-like 2 Ellagic Acid results in increased expression of NFE2L2 mRNA increases expression
mRNA 22386815
D004610 4780 NFE2L2
NRF2
nuclear factor, erythroid 2-like 2 NFE2L2 protein affects the susceptibility to Ellagic Acid affects response to substance
protein 22386815
D004610 4791 NFKB2
H2TF1
LYT-10
LYT10
NF-kB2
p105
p52
nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100) Ellagic Acid results in decreased expression of NFKB2 mRNA decreases expression
mRNA 12002526
D004610 4826 NNAT
Peg5
neuronatin Ellagic Acid results in increased expression of NNAT mRNA increases expression
mRNA 12002526
D004610 10528 NOP56
NOL5A
SCA36
NOP56 ribonucleoprotein Ellagic Acid results in decreased expression of NOP56 mRNA decreases expression
mRNA 12002526
D004610 4862 NPAS2
MOP4
PASD4
bHLHe9
neuronal PAS domain protein 2 Ellagic Acid results in increased expression of NPAS2 mRNA increases expression
mRNA 12002526
D004610 9970 NR1I3
CAR
CAR1
MB67
nuclear receptor subfamily 1, group I, member 3 Ellagic Acid results in increased activity of NR1I3 protein increases activity
protein 21821919
D004610 8505 PARG
PARG99
poly (ADP-ribose) glycohydrolase (EC:3.2.1.143) Ellagic Acid results in decreased activity of PARG protein decreases activity
protein 19840838
D004610 5320 PLA2G2A
MOM1
PLA2
PLA2B
PLA2L
PLA2S
PLAS1
sPLA2
phospholipase A2, group IIA (platelets, synovial fluid) (EC:3.1.1.4) Ellagic Acid results in decreased expression of PLA2G2A mRNA decreases expression
mRNA 20816778
D004610 5355 PLP2
A4
A4LSB
proteolipid protein 2 (colonic epithelium-enriched) Ellagic Acid results in increased expression of PLP2 mRNA increases expression
mRNA 12002526
D004610 5371 PML
MYL
PP8675
RNF71
TRIM19
promyelocytic leukemia Ellagic Acid results in decreased expression of PML mRNA decreases expression
mRNA 12002526
D004610 5467 PPARD
FAAR
NR1C2
NUC1
NUCI
NUCII
PPARB
peroxisome proliferator-activated receptor delta Ellagic Acid results in decreased expression of PPARD mRNA decreases expression
mRNA 12002526
D004610 5592 PRKG1
1
AAT8
PKG
PRKG1B
PRKGR1B
cGK
cGK_1
cGK1
cGKI
cGKI-BETA
cGKI-alpha
protein kinase, cGMP-dependent, type I (EC:2.7.11.12) Ellagic Acid results in decreased expression of PRKG1 mRNA decreases expression
mRNA 12002526
D004610 5764 PTN
HARP
HBGF8
HBNF
NEGF1
pleiotrophin Ellagic Acid results in decreased expression of PTN mRNA decreases expression
mRNA 12002526
D004610 5764 PTN
HARP
HBGF8
HBNF
NEGF1
pleiotrophin Ellagic Acid results in increased expression of PTN mRNA increases expression
mRNA 12002526
D004610 5799 PTPRN2
IA-2beta
IAR
ICAAR
PTPRP
R-PTP-N2
protein tyrosine phosphatase, receptor type, N polypeptide 2 (EC:3.1.3.48) Ellagic Acid results in increased expression of PTPRN2 mRNA increases expression
mRNA 12002526
D004610 5901 RAN
ARA24
Gsp1
TC4
RAN, member RAS oncogene family Ellagic Acid results in decreased expression of RAN mRNA decreases expression
mRNA 12002526
D004610 8434 RECK
ST15
reversion-inducing-cysteine-rich protein with kazal motifs Ellagic Acid results in increased expression of RECK mRNA increases expression
mRNA 21573219
D004610 8434 RECK
ST15
reversion-inducing-cysteine-rich protein with kazal motifs Ellagic Acid results in increased expression of RECK protein increases expression
protein 21573219
D004610 8434 RECK
ST15
reversion-inducing-cysteine-rich protein with kazal motifs zinc chloride inhibits the reaction [Ellagic Acid results in increased expression of RECK mRNA] decreases reaction
/ increases expression
mRNA 21573219
D004610 8434 RECK
ST15
reversion-inducing-cysteine-rich protein with kazal motifs zinc chloride inhibits the reaction [Ellagic Acid results in increased expression of RECK protein] decreases reaction
/ increases expression
protein 21573219
D004610 5970 RELA
NFKB3
p65
v-rel avian reticuloendotheliosis viral oncogene homolog A Ellagic Acid results in decreased expression of RELA mRNA decreases expression
mRNA 12002526
D004610 8490 RGS5
MST092
MST106
MST129
MSTP032
MSTP092
MSTP106
MSTP129
regulator of G-protein signaling 5 Ellagic Acid results in decreased expression of RGS5 mRNA decreases expression
mRNA 12002526
D004610 6319 SCD
FADS5
MSTP008
SCD1
SCDOS
stearoyl-CoA desaturase (delta-9-desaturase) (EC:1.14.19.1) Ellagic Acid results in decreased expression of SCD mRNA decreases expression
mRNA 20816778
D004610 4735 SEPT2
DIFF6
NEDD-5
NEDD5
Pnutl3
hNedd5
septin 2 Ellagic Acid results in increased expression of SEPT2 mRNA increases expression
mRNA 12002526
D004610 6649 SOD3
EC-SOD
superoxide dismutase 3, extracellular (EC:1.15.1.1) Ellagic Acid results in decreased expression of SOD3 mRNA decreases expression
mRNA 12002526
D004610 6774 STAT3
APRF
HIES
signal transducer and activator of transcription 3 (acute-phase response factor) Ellagic Acid results in decreased expression of STAT3 mRNA decreases expression
mRNA 20816778
D004610 6774 STAT3
APRF
HIES
signal transducer and activator of transcription 3 (acute-phase response factor) Ellagic Acid results in increased expression of STAT3 mRNA increases expression
mRNA 12002526
D004610 9013 TAF1C
MGC:39976
SL1
TAFI110
TAFI95
TATA box binding protein (TBP)-associated factor, RNA polymerase I, C, 110kDa Ellagic Acid results in decreased expression of TAF1C mRNA decreases expression
mRNA 12002526
D004610 6938 TCF12
CRS3
HEB
HTF4
HsT17266
bHLHb20
transcription factor 12 Ellagic Acid results in increased expression of TCF12 mRNA increases expression
mRNA 12002526
D004610 7015 TERT
CMM9
DKCA2
DKCB4
EST2
PFBMFT1
TCS1
TP2
TRT
hEST2
hTRT
telomerase reverse transcriptase (EC:2.7.7.49) Ellagic Acid inhibits the reaction [Estradiol results in increased expression of TERT mRNA alternative form] decreases reaction
/ increases expression
mRNA 19501078
D004610 7015 TERT
CMM9
DKCA2
DKCB4
EST2
PFBMFT1
TCS1
TP2
TRT
hEST2
hTRT
telomerase reverse transcriptase (EC:2.7.7.49) Ellagic Acid results in increased expression of TERT mRNA alternative form increases expression
mRNA 19501078
D004610 7019 TFAM
MTTF1
MTTFA
TCF6
TCF6L1
TCF6L2
TCF6L3
transcription factor A, mitochondrial Ellagic Acid results in decreased expression of TFAM mRNA decreases expression
mRNA 12002526
D004610 7040 TGFB1
CED
DPD1
LAP
TGFB
TGFbeta
transforming growth factor, beta 1 Ellagic Acid results in increased expression of TGFB1 mRNA increases expression
mRNA 12002526
D004610 7360 UGP2
UDPG
UDPGP
UDPGP2
UGP1
UGPP1
UGPP2
pHC379
UDP-glucose pyrophosphorylase 2 (EC:2.7.7.9) Ellagic Acid results in decreased expression of UGP2 mRNA decreases expression
mRNA 12002526
D004610 7375 USP4
UNP
Unph
ubiquitin specific peptidase 4 (proto-oncogene) (EC:3.4.19.12) Ellagic Acid results in decreased expression of USP4 mRNA decreases expression
mRNA 12002526
D004610 7453 WARS
GAMMA-2
IFI53
IFP53
tryptophanyl-tRNA synthetase (EC:6.1.1.2) Ellagic Acid results in increased expression of WARS mRNA increases expression
mRNA 12002526
D004610 7704 ZBTB16
PLZF
ZNF145
zinc finger and BTB domain containing 16 Ellagic Acid results in decreased expression of ZBTB16 mRNA decreases expression
mRNA 12002526
D004610 7750 ZMYM2
FIM
MYM
RAMP
SCLL
ZNF198
zinc finger, MYM-type 2 Ellagic Acid results in increased expression of ZMYM2 mRNA increases expression
mRNA 12002526

Related Disease

Diseases related to proteins in ChEMBL interactions

OMIM (97)

OMIM preferred title UniProt
#300438 17-beta-hydroxysteroid dehydrogenase x deficiency Q99714
#202300 Adrenocortical carcinoma, hereditary; adcc P04637
#208900 Ataxia-telangiectasia; at Q13315
#614740 Basal cell carcinoma, susceptibility to, 7; bcc7 P04637
#615007 Basal ganglia calcification, idiopathic, 4; ibgc4 P09619
#613985 Beta-thalassemia P68871
#603902 Beta-thalassemia, dominant inclusion body type P68871
#210900 Bloom syndrome; blm P54132
#114480 Breast cancer P31749
#115150 Cardiofaciocutaneous syndrome 1; cfc1 P15056
#115200 Cardiomyopathy, dilated, 1a; cmd1a P02545
#212112 Cardiomyopathy, dilated, with hypergonadotropic hypogonadism P02545
#209880 Central hypoventilation syndrome, congenital; cchs P07949
#605588 Charcot-marie-tooth disease, axonal, type 2b1; cmt2b1 P02545
#114500 Colorectal cancer; crc P07949
P15056
P31749
P84022
#615109 Cowden syndrome 6; cws6 P31749
#610549 Diabetes mellitus, insulin-resistant, with acanthosis nigricans P06213
#125853 Diabetes mellitus, noninsulin-dependent; niddm P06213
#119900 Digital clubbing, isolated congenital P15428
#246200 Donohue syndrome P06213
#609535 Drug metabolism, poor, cyp2c19-related P33261
#181350 Emery-dreifuss muscular dystrophy 2, autosomal dominant; edmd2 P02545
#133239 Esophageal cancer P04637
#600274 Frontotemporal dementia; ftd P10636
#613659 Gastric cancer P04626
#137215 Gastric cancer, hereditary diffuse; hdgc P04626
#137800 Glioma susceptibility 1; glm1 O75874
P04626
#232300 Glycogen storage disease ii P10253
#605130 Hairy elbows, short stature, facial dysmorphism, and developmental delay Q03164
#610140 Heart-hand syndrome, slovenian type P02545
#140700 Heinz body anemias P68871
#602089 Hemangioma, capillary infantile P35916
P35968
#614519 Hemorrhage, intracerebral, susceptibility to; ich P12821
#114550 Hepatocellular carcinoma P08581
#142623 Hirschsprung disease, susceptibility to, 1; hscr1 P07949
#176670 Hutchinson-gilford progeria syndrome; hgps P02545
#143860 Hyperchlorhidrosis, isolated O43570
#609968 Hyperinsulinemic hypoglycemia, familial, 5; hhf5 P06213
#145000 Hyperparathyroidism 1; hrpt1 O00255
#259100 Hypertrophic osteoarthropathy, primary, autosomal recessive, 1; phoar1 P15428
#270450 Insulin-like growth factor i, resistance to P08069
#607785 Juvenile myelomonocytic leukemia; jmml P09619
#613707 Leopard syndrome 3 P15056
#601626 Leukemia, acute myeloid; aml P09619
P36888
#151623 Li-fraumeni syndrome 1; lfs1 P04637
#151660 Lipodystrophy, familial partial, type 2; fpld2 P02545
#613795 Loeys-dietz syndrome, type 3; lds3 P84022
#211980 Lung cancer P00533
P04626
P04637
P15056
#153100 Lymphedema, hereditary, ia P35916
#605027 Lymphoma, non-hodgkin, familial P15056
#248370 Mandibuloacral dysplasia with type a lipodystrophy; mada P02545
#609048 Melanoma, cutaneous malignant, susceptibility to, 3; cmm3 P11802
#614104 Mental retardation, autosomal dominant 7; mrd7 Q13627
#300705 Mental retardation, x-linked 17; mrx17 Q99714
#300220 Mental retardation, x-linked, syndromic 10; mrxs10 Q99714
#612624 Microvascular complications of diabetes, susceptibility to, 3; mvcd3 P12821
#131100 Multiple endocrine neoplasia, type i; men1 O00255
#171400 Multiple endocrine neoplasia, type iia; men2a P07949
#162300 Multiple endocrine neoplasia, type iib; men2b P07949
#613205 Muscular dystrophy, congenital, lmna-related P02545
#159001 Muscular dystrophy, limb-girdle, type 1b; lgmd1b P02545
#607948 Mycobacterium tuberculosis, susceptibility to P11473
#254500 Myeloma, multiple P24385
#131440 Myeloproliferative disorder, chronic, with eosinophilia P09619
#228550 Myofibromatosis, infantile, 1; imf1 P09619
#160900 Myotonic dystrophy 1; dm1 Q9NR56
#613014 Neuroblastoma, susceptibility to, 3; nblst3 Q9UM73
#613706 Noonan syndrome 7; ns7 P15056
#259730 Osteopetrosis, autosomal recessive 3; optb3 P00918
#167000 Ovarian cancer P04626
#260500 Papilloma of choroid plexus; cpp P04637
#260540 Parkinson-dementia syndrome P10636
#171300 Pheochromocytoma P07949
#172700 Pick disease of brain P10636
#262190 Pineal hyperplasia, insulin-resistant diabetes mellitus, and somatic abnormalities P06213
#601399 Platelet disorder, familial, with associated myeloid malignancy Q01196
#176920 Proteus syndrome P31749
#191830 Renal adysplasia P07949
#605074 Renal cell carcinoma, papillary, 1; rccp1 P08581
#267430 Renal tubular dysgenesis; rtd P12821
#275210 Restrictive dermopathy, lethal P02545
#600852 Retinitis pigmentosa 17; rp17 P22748
#604906 Schizophrenia 9; sczd9 P49798
#181500 Schizophrenia; sczd P49798
#603903 Sickle cell anemia P68871
#607250 Spinocerebellar ataxia, autosomal recessive, with axonal neuropathy; scan1 Q9NUW8
#275355 Squamous cell carcinoma, head and neck; hnscc P04637
#601367 Stroke, ischemic P12821
#601104 Supranuclear palsy, progressive, 1; psnp1 P10636
#155240 Thyroid carcinoma, familial medullary; mtc P07949
#188550 Thyroid carcinoma, papillary P07949
#188570 Thyroid hormone resistance, generalized, autosomal dominant; grth P10828
#274300 Thyroid hormone resistance, generalized, autosomal recessive; grth P10828
#145650 Thyroid hormone resistance, selective pituitary; prth P10828
#600195 Venous malformations, multiple cutaneous and mucosal; vmcm Q02763
#277440 Vitamin d-dependent rickets, type 2a; vddr2a P11473
#278750 Xeroderma pigmentosum, variant type; xpv Q9Y253

KEGG DISEASE (100)

KEGG disease name UniProt
H00033 Adrenal carcinoma O00255 (related)
P04637 (related)
H00034 Carcinoid O00255 (related)
H00045 Malignant islet cell carcinoma O00255 (related)
H00246 Primary hyperparathyroidism O00255 (related)
H01102 Pituitary adenomas O00255 (related)
H01302 Hyperchlorhidrosis isolated (HCHLH) O43570 (related)
H00021 Renal cell carcinoma O43570 (marker)
P04637 (marker)
P08581 (related)
Q16790 (marker)
H00016 Oral cancer P00533 (related)
P00533 (marker)
P04637 (related)
P04637 (marker)
P24385 (related)
P24385 (marker)
H00017 Esophageal cancer P00533 (related)
P04637 (related)
P04637 (marker)
P24385 (related)
H00018 Gastric cancer P00533 (related)
P04626 (related)
P04637 (related)
P08581 (related)
H00022 Bladder cancer P00533 (related)
P04626 (related)
P04637 (related)
P68871 (marker)
H00028 Choriocarcinoma P00533 (related)
P04626 (related)
P04637 (related)
H00030 Cervical cancer P00533 (related)
P04626 (related)
P11802 (related)
H00042 Glioma P00533 (related)
P00533 (marker)
P04637 (related)
P04637 (marker)
P09619 (related)
P11802 (related)
H00055 Laryngeal cancer P00533 (related)
P00533 (marker)
P04637 (related)
P04637 (marker)
P24385 (related)
P24385 (marker)
H00241 Combined proximal and distal renal tubular acidosis (RTA type 3) P00918 (related)
H00436 Osteopetrosis P00918 (related)
H00264 Charcot-Marie-Tooth disease (CMT) P02545 (related)
H00294 Dilated cardiomyopathy (DCM) P02545 (related)
H00420 Familial partial lipodystrophy (FPL) P02545 (related)
H00563 Emery-Dreifuss muscular dystrophy P02545 (related)
H00590 Congenital muscular dystrophies (CMD/MDC) P02545 (related)
H00593 Limb-girdle muscular dystrophy (LGMD) P02545 (related)
H00601 Hutchinson-Gilford progeria syndrome P02545 (related)
H00663 Restrictive dermopathy P02545 (related)
H00665 Mandibuloacral dysplasia P02545 (related)
H01216 Left ventricular noncompaction (LVNC) P02545 (related)
H00019 Pancreatic cancer P04626 (related)
P04637 (related)
P04637 (marker)
H00026 Endometrial Cancer P04626 (related)
P04637 (related)
H00027 Ovarian cancer P04626 (related)
P04637 (related)
H00031 Breast cancer P04626 (related)
P04626 (marker)
P04637 (related)
P24385 (related)
H00046 Cholangiocarcinoma P04626 (related)
P04637 (related)
P08581 (related)
H00004 Chronic myeloid leukemia (CML) P04637 (related)
Q01196 (related)
H00005 Chronic lymphocytic leukemia (CLL) P04637 (related)
Q13315 (related)
H00006 Hairy-cell leukemia P04637 (related)
P24385 (related)
H00008 Burkitt lymphoma P04637 (related)
H00009 Adult T-cell leukemia P04637 (related)
H00010 Multiple myeloma P04637 (related)
P24385 (related)
H00013 Small cell lung cancer P04637 (related)
H00014 Non-small cell lung cancer P04637 (related)
Q9UM73 (related)
H00015 Malignant pleural mesothelioma P04637 (related)
P08069 (related)
H00020 Colorectal cancer P04637 (related)
P04637 (marker)
P68871 (marker)
H00025 Penile cancer P04637 (related)
P04637 (marker)
H00029 Vulvar cancer P04637 (related)
H00032 Thyroid cancer P04637 (related)
P07949 (related)
P07949 (marker)
P15056 (related)
H00036 Osteosarcoma P04637 (related)
H00038 Malignant melanoma P04637 (related)
P11802 (related)
P15056 (related)
H00039 Basal cell carcinoma P04637 (related)
H00040 Squamous cell carcinoma P04637 (related)
H00041 Kaposi's sarcoma P04637 (related)
H00044 Cancer of the anal canal P04637 (related)
H00047 Gallbladder cancer P04637 (related)
P24385 (marker)
H00048 Hepatocellular carcinoma P04637 (related)
H00881 Li-Fraumeni syndrome P04637 (related)
H01007 Choroid plexus papilloma P04637 (related)
H00719 Leprechaunism P06213 (related)
H00942 Rabson-Mendenhall syndrome P06213 (related)
H01228 Insulin-resistant diabetes mellitus with acanthosis nigricans (IRAN) P06213 (related)
H01267 Familial hyperinsulinemic hypoglycemia (HHF) P06213 (related)
H00822 Renal agenesis and Renal adysplasia P07949 (related)
H00910 Hirschsprung disease (HD) P07949 (related)
H00916 Congenital central hypoventilation syndrome (CCHS) P07949 (related)
H00050 Synovial sarcoma P08069 (related)
H01274 Growth delay due to insulin-like growth factor I resistance P08069 (related)
H00024 Prostate cancer P09211 (related)
P09211 (marker)
H00069 Glycogen storage diseases (GSD) P10253 (related)
H00058 Amyotrophic lateral sclerosis (ALS) P10636 (related)
H00077 Progressive supranuclear palsy (PSP) P10636 (related)
H00078 Frontotemporal lobar degeneration (FTLD) P10636 (related)
H00249 Thyroid hormone resistance syndrome P10828 (related)
H00342 Tuberculosis P11473 (related)
H00784 Localized autosomal recessive hypotrichosis P11473 (related)
H01143 Vitamin D-dependent rickets P11473 (related)
H01205 Coumarin resistance P11712 (related)
H00083 Allograft rejection P12821 (related)
H00575 Renal tubular dysgenesis P12821 (related)
H00523 Noonan syndrome and related disorders P15056 (related)
H00457 Primary hypertrophic osteoarthropathy (PHO) P15428 (related)
H01246 Isolated congenital nail clubbing (ICNC) P15428 (related)
H00527 Retinitis pigmentosa (RP) P22748 (related)
H00559 von Hippel-Lindau syndrome P24385 (related)
H00539 PTEN hamartoma tumor syndrome (PHTS) P31749 (related)
H01171 Poor drug metabolism (PM) P33261 (related)
H00535 Lymphedemas P35916 (related)
H00003 Acute myeloid leukemia (AML) P36888 (related)
Q01196 (related)
Q01196 (marker)
Q13951 (marker)
H00094 DNA repair defects P54132 (related)
Q13315 (related)
H00296 Defects in RecQ helicases P54132 (related)
H00228 Thalassemia P68871 (related)
H00229 Sickle cell anemia (SCA) P68871 (related)
H00001 Acute lymphoblastic leukemia (ALL) (precursor B lymphoblastic leukemia) Q01196 (related)
Q01196 (marker)
Q03164 (related)
Q03164 (marker)
H00978 Thrombocytopenia (THC) Q01196 (related)
H00531 Venous malformations Q02763 (related)
H00002 Acute lymphoblastic leukemia (ALL) (precursor T lymphoblastic leukemia) Q03164 (related)
H00064 Ataxia telangiectasia (AT) Q13315 (related)
H00848 Ataxia with ocular apraxia (AOA) Q13315 (related)
H00480 Non-syndromic X-linked mental retardation Q99714 (related)
H00658 Syndromic X-linked mental retardation Q99714 (related)
H00925 2-Methyl-3-hydroxybutyryl-CoA dehydrogenase (MHBD) deficiency Q99714 (related)
H00063 Spinocerebellar ataxia (SCA) Q9NUW8 (related)
H00403 Disorders of nucleotide excision repair Q9Y253 (related)

Diseases related to CTD interactions

9 disease from interactions of metabolites

MeSH disease OMIM compound disease name evidence type reference
pmid
D000014 D004610 Abnormalities, Drug-Induced therapeutic
9650642
D002471 D004610 Cell Transformation, Neoplastic therapeutic
19329757
D006965 D004610 Hyperplasia therapeutic
19329757
20103723
D007248 D004610 Infertility, Male therapeutic
20074268
D009203 D004610 Myocardial Infarction therapeutic
21762681
D015427 D004610 Reperfusion Injury therapeutic
9650642
D012878 D004610 Skin Neoplasms therapeutic
19329757
D013471 D004610 Sunburn therapeutic
22386815
D013733 D004610 Testicular Diseases therapeutic
20074268