id | C00002253 |
---|---|
Name | Jervine |
CAS RN | 469-59-0 |
Standard InChI | InChI=1S/C27H39NO3/c1-14-11-21-24(28-13-14)16(3)27(31-21)10-8-19-20-6-5-17-12-18(29)7-9-26(17,4)23(20)25(30)22(19)15(27)2/h5,14,16,18-21,23-24,28-29H,6-13H2,1-4H3/t14-,16+,18-,19-,20-,21+,23+,24-,26-,27-/m0/s1 |
Standard InChI (Main Layer) | InChI=1S/C27H39NO3/c1-14-11-21-24(28-13-14)16(3)27(31-21)10-8-19-20-6-5-17-12-18(29)7-9-26(17,4)23(20)25(30)22(19)15(27)2/h5,14,16,18-21,23-24,28-29H,6-13H2,1-4H3 |
Phytochemical cluster | No. 11 |
---|---|
KCF-S cluster | No. 587 |
By standard InChI | CHEMBL186779 |
---|---|
By standard InChI Main Layer | CHEMBL186779 CHEMBL1402135 CHEMBL1717145 CHEMBL1742371 |
By LinkDB | C10811 |
---|
By CAS RN | C010206 |
---|
class name | count |
---|---|
Liliopsida | 9 |
family name | count |
---|---|
Melanthiaceae | 9 |
accession | description | class description | compound | assay ID (# of activities) |
# of diseases
(OMIM / KEGG) |
---|---|---|---|---|---|
Q15125 | 3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase | Enzyme | CHEMBL186779 |
CHEMBL829736
(1)
|
1 / 1 |
P10635 | Cytochrome P450 2D6 | Cytochrome P450 2D6 | CHEMBL1742371 |
CHEMBL1741321
(1)
|
1 / 0 |
P11712 | Cytochrome P450 2C9 | Cytochrome P450 2C9 | CHEMBL1742371 |
CHEMBL1741325
(1)
|
0 / 1 |
Q15465 | Sonic hedgehog protein | Unclassified protein | CHEMBL186779 |
CHEMBL972423
(1)
|
4 / 5 |
Q92830 | Histone acetyltransferase KAT2A | Enzyme | CHEMBL1717145 |
CHEMBL1738606
(1)
|
0 / 0 |
Q99720 | Sigma non-opioid intracellular receptor 1 | Membrane receptor | CHEMBL186779 |
CHEMBL839610
(1)
|
1 / 0 |
P63092 | Guanine nucleotide-binding protein G(s) subunit alpha isoforms short | Other membrane protein | CHEMBL1402135 |
CHEMBL2114810
(1)
|
7 / 3 |
P05177 | Cytochrome P450 1A2 | Cytochrome P450 1A2 | CHEMBL1742371 |
CHEMBL1741322
(1)
|
0 / 0 |
P33261 | Cytochrome P450 2C19 | Cytochrome P450 2C19 | CHEMBL1742371 |
CHEMBL1741323
(1)
|
1 / 1 |
P08684 | Cytochrome P450 3A4 | Cytochrome P450 3A4 | CHEMBL1742371 |
CHEMBL1741324
(1)
|
0 / 1 |
Q9UNA4 | DNA polymerase iota | Enzyme | CHEMBL1402135 |
CHEMBL1794483
(1)
|
0 / 0 |
OMIM | preferred title | UniProt |
---|---|---|
#219080 | Acth-independent macronodular adrenal hyperplasia; aimah |
P63092
|
#614373 | Amyotrophic lateral sclerosis 16, juvenile; als16 |
Q99720
|
#302960 | Chondrodysplasia punctata 2, x-linked dominant; cdpx2 |
Q15125
|
#609535 | Drug metabolism, poor, cyp2c19-related |
P33261
|
#608902 | Drug metabolism, poor, cyp2d6-related |
P10635
|
#142945 | Holoprosencephaly 3; hpe3 |
Q15465
|
#174800 | Mccune-albright syndrome; mas |
P63092
|
#611638 | Microphthalmia, isolated, with coloboma 5; mcopcb5 |
Q15465
|
#166350 | Osseous heteroplasia, progressive; poh |
P63092
|
#102200 | Pituitary adenoma, growth hormone-secreting |
P63092
|
#174500 | Polydactyly, preaxial ii; ppd2 |
Q15465
|
#103580 | Pseudohypoparathyroidism, type ia; php1a |
P63092
|
#603233 | Pseudohypoparathyroidism, type ib; php1b |
P63092
|
#612462 | Pseudohypoparathyroidism, type ic; php1c |
P63092
|
#147250 | Solitary median maxillary central incisor; smmci |
Q15465
|
KEGG | disease name | UniProt |
---|---|---|
H00036 | Osteosarcoma |
P08684
(marker)
|
H01205 | Coumarin resistance |
P11712
(related)
|
H01171 | Poor drug metabolism (PM) |
P33261
(related)
|
H00244 | Pseudohypoparathyroidism |
P63092
(related)
|
H00441 | Progressive osseous heteroplasia (POH) |
P63092
(related)
|
H00501 | Fibrous dysplasia, polyostotic |
P63092
(related)
|
H01194 | X-linked chondrodysplasia punctata |
Q15125
(related)
|
H00039 | Basal cell carcinoma |
Q15465
(related)
|
H00267 | Holoprosencephaly (HPE) |
Q15465
(related)
|
H00652 | Solitary median maxillary central incisor syndrome |
Q15465
(related)
|
H01027 | Anophthalmia and microphthalmia (A/M) |
Q15465
(related)
|
H01160 | Schizencephaly |
Q15465
(related)
|