PCIDB

KNApSAcK Metabolite C00030402

Metabolite

KNApSAcK Entry

id C00030402
Name Ginsenoside Rh1
CAS RN 63223-86-9
Standard InChI InChI=1S/C36H62O9/c1-19(2)10-9-13-36(8,43)20-11-15-34(6)26(20)21(38)16-24-33(5)14-12-25(39)32(3,4)30(33)22(17-35(24,34)7)44-31-29(42)28(41)27(40)23(18-37)45-31/h10,20-31,37-43H,9,11-18H2,1-8H3/t20-,21+,22-,23+,24+,25-,26-,27+,28-,29+,30-,31+,33+,34+,35+,36-/m0/s1
Standard InChI (Main Layer) InChI=1S/C36H62O9/c1-19(2)10-9-13-36(8,43)20-11-15-34(6)26(20)21(38)16-24-33(5)14-12-25(39)32(3,4)30(33)22(17-35(24,34)7)44-31-29(42)28(41)27(40)23(18-37)45-31/h10,20-31,37-43H,9,11-18H2,1-8H3

Cluster

Phytochemical cluster
KCF-S cluster No. 99

Link

ChEMBL

By standard InChI CHEMBL466844
By standard InChI Main Layer CHEMBL466844

KEGG

By LinkDB

CTD

By CAS RN C425564

Human Protein / Gene in interaction

CTD interaction (13)

compound gene gene name gene description interaction interaction type form reference
pmid
C425564 3383 ICAM1
BB2
CD54
P3.58
intercellular adhesion molecule 1 ginsenoside Rh1 inhibits the reaction [TNF protein results in increased expression of ICAM1 protein] decreases reaction
/ increases expression
protein 21875580
C425564 3676 ITGA4
CD49D
IA4
integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor) ginsenoside Rh1 inhibits the reaction [TNF protein results in increased expression of [ITGA4 protein binds to ITGB1 protein]] affects binding
/ decreases reaction
/ increases expression
protein 21875580
C425564 3683 ITGAL
CD11A
LFA-1
LFA1A
integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide) ginsenoside Rh1 inhibits the reaction [TNF protein results in increased expression of [ITGAL protein binds to ITGB2 protein]] affects binding
/ decreases reaction
/ increases expression
protein 21875580
C425564 3688 ITGB1
CD29
FNRB
GPIIA
MDF2
MSK12
VLA-BETA
VLAB
integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) ginsenoside Rh1 inhibits the reaction [TNF protein results in increased expression of [ITGA4 protein binds to ITGB1 protein]] affects binding
/ decreases reaction
/ increases expression
protein 21875580
C425564 3689 ITGB2
CD18
LAD
LCAMB
LFA-1
MAC-1
MF17
MFI7
integrin, beta 2 (complement component 3 receptor 3 and 4 subunit) ginsenoside Rh1 inhibits the reaction [TNF protein results in increased expression of [ITGAL protein binds to ITGB2 protein]] affects binding
/ decreases reaction
/ increases expression
protein 21875580
C425564 6401 SELE
CD62E
ELAM
ELAM1
ESEL
LECAM2
selectin E ginsenoside Rh1 inhibits the reaction [TNF protein results in increased expression of SELE protein] decreases reaction
/ increases expression
protein 21875580
C425564 7124 TNF
DIF
TNF-alpha
TNFA
TNFSF2
tumor necrosis factor ginsenoside Rh1 inhibits the reaction [TNF protein results in increased expression of ICAM1 protein] decreases reaction
/ increases expression
protein 21875580
C425564 7124 TNF
DIF
TNF-alpha
TNFA
TNFSF2
tumor necrosis factor ginsenoside Rh1 inhibits the reaction [TNF protein results in increased expression of [ITGA4 protein binds to ITGB1 protein]] affects binding
/ decreases reaction
/ increases expression
protein 21875580
C425564 7124 TNF
DIF
TNF-alpha
TNFA
TNFSF2
tumor necrosis factor ginsenoside Rh1 inhibits the reaction [TNF protein results in increased expression of [ITGAL protein binds to ITGB2 protein]] affects binding
/ decreases reaction
/ increases expression
protein 21875580
C425564 7124 TNF
DIF
TNF-alpha
TNFA
TNFSF2
tumor necrosis factor ginsenoside Rh1 inhibits the reaction [TNF protein results in increased expression of SELE protein] decreases reaction
/ increases expression
protein 21875580
C425564 7124 TNF
DIF
TNF-alpha
TNFA
TNFSF2
tumor necrosis factor ginsenoside Rh1 inhibits the reaction [TNF protein results in increased expression of VCAM1 protein] decreases reaction
/ increases expression
protein 21875580
C425564 7124 TNF
DIF
TNF-alpha
TNFA
TNFSF2
tumor necrosis factor ginsenoside Rh1 results in decreased susceptibility to TNF protein decreases response to substance
protein 21875580
C425564 7412 VCAM1
CD106
INCAM-100
vascular cell adhesion molecule 1 ginsenoside Rh1 inhibits the reaction [TNF protein results in increased expression of VCAM1 protein] decreases reaction
/ increases expression
protein 21875580