id | C00003548 |
---|---|
Name | Saikosaponin A |
CAS RN | 20736-09-8 |
Standard InChI | InChI=1S/C42H68O13/c1-21-28(46)33(55-34-31(49)30(48)29(47)22(18-43)53-34)32(50)35(52-21)54-27-10-11-37(4)23(38(27,5)19-44)8-12-39(6)24(37)9-13-42-25-16-36(2,3)14-15-41(25,20-51-42)26(45)17-40(39,42)7/h9,13,21-35,43-50H,8,10-12,14-20H2,1-7H3/t21?,22?,23-,24-,25-,26+,27+,28+,29-,30+,31?,32?,33+,34+,35+,37+,38+,39-,40+,41-,42+/m1/s1 |
Standard InChI (Main Layer) | InChI=1S/C42H68O13/c1-21-28(46)33(55-34-31(49)30(48)29(47)22(18-43)53-34)32(50)35(52-21)54-27-10-11-37(4)23(38(27,5)19-44)8-12-39(6)24(37)9-13-42-25-16-36(2,3)14-15-41(25,20-51-42)26(45)17-40(39,42)7/h9,13,21-35,43-50H,8,10-12,14-20H2,1-7H3 |
Phytochemical cluster | No. 51 |
---|---|
KCF-S cluster | No. 11 |
By standard InChI | |
---|---|
By standard InChI Main Layer | CHEMBL1159434 CHEMBL1159438 CHEMBL1703199 |
By LinkDB | C08975 |
---|
By CAS RN |
---|
KNApSAcK organism | *ID | *family | *plant class | *kingdom |
---|---|---|---|---|
Bupleurum chinense | 52451 | Apiaceae | asterids | Viridiplantae |
Bupleurum falcatum | 46367 | Apiaceae | asterids | Viridiplantae |
accession | description | class description | compound | assay ID (# of activities) |
# of diseases
(OMIM / KEGG) |
---|---|---|---|---|---|
P04637 | Cellular tumor antigen p53 | Transcription Factor | CHEMBL1703199 |
CHEMBL1738132
(1)
|
7 / 44 |
P84022 | Mothers against decapentaplegic homolog 3 | Unclassified protein | CHEMBL1703199 |
CHEMBL1794584
(1)
|
2 / 0 |
O75496 | Geminin | Unclassified protein | CHEMBL1703199 |
CHEMBL2114843
(1)
CHEMBL2114780
(1)
|
0 / 0 |
Q96QE3 | ATPase family AAA domain-containing protein 5 | Unclassified protein | CHEMBL1703199 |
CHEMBL1738588
(1)
|
0 / 0 |
Q9UNA4 | DNA polymerase iota | Enzyme | CHEMBL1703199 |
CHEMBL1794483
(1)
|
0 / 0 |
OMIM | preferred title | UniProt |
---|---|---|
#202300 | Adrenocortical carcinoma, hereditary; adcc |
P04637
|
#614740 | Basal cell carcinoma, susceptibility to, 7; bcc7 |
P04637
|
#114500 | Colorectal cancer; crc |
P84022
|
#133239 | Esophageal cancer |
P04637
|
#151623 | Li-fraumeni syndrome 1; lfs1 |
P04637
|
#613795 | Loeys-dietz syndrome, type 3; lds3 |
P84022
|
#211980 | Lung cancer |
P04637
|
#260500 | Papilloma of choroid plexus; cpp |
P04637
|
#275355 | Squamous cell carcinoma, head and neck; hnscc |
P04637
|
KEGG | disease name | UniProt |
---|---|---|
H00004 | Chronic myeloid leukemia (CML) |
P04637
(related)
|
H00005 | Chronic lymphocytic leukemia (CLL) |
P04637
(related)
|
H00006 | Hairy-cell leukemia |
P04637
(related)
|
H00008 | Burkitt lymphoma |
P04637
(related)
|
H00009 | Adult T-cell leukemia |
P04637
(related)
|
H00010 | Multiple myeloma |
P04637
(related)
|
H00013 | Small cell lung cancer |
P04637
(related)
|
H00014 | Non-small cell lung cancer |
P04637
(related)
|
H00015 | Malignant pleural mesothelioma |
P04637
(related)
|
H00016 | Oral cancer |
P04637
(related)
P04637 (marker) |
H00017 | Esophageal cancer |
P04637
(related)
P04637 (marker) |
H00018 | Gastric cancer |
P04637
(related)
|
H00019 | Pancreatic cancer |
P04637
(related)
P04637 (marker) |
H00020 | Colorectal cancer |
P04637
(related)
P04637 (marker) |
H00022 | Bladder cancer |
P04637
(related)
|
H00025 | Penile cancer |
P04637
(related)
P04637 (marker) |
H00026 | Endometrial Cancer |
P04637
(related)
|
H00027 | Ovarian cancer |
P04637
(related)
|
H00028 | Choriocarcinoma |
P04637
(related)
|
H00029 | Vulvar cancer |
P04637
(related)
|
H00031 | Breast cancer |
P04637
(related)
|
H00032 | Thyroid cancer |
P04637
(related)
|
H00033 | Adrenal carcinoma |
P04637
(related)
|
H00036 | Osteosarcoma |
P04637
(related)
|
H00038 | Malignant melanoma |
P04637
(related)
|
H00039 | Basal cell carcinoma |
P04637
(related)
|
H00040 | Squamous cell carcinoma |
P04637
(related)
|
H00041 | Kaposi's sarcoma |
P04637
(related)
|
H00042 | Glioma |
P04637
(related)
P04637 (marker) |
H00044 | Cancer of the anal canal |
P04637
(related)
|
H00046 | Cholangiocarcinoma |
P04637
(related)
|
H00047 | Gallbladder cancer |
P04637
(related)
|
H00048 | Hepatocellular carcinoma |
P04637
(related)
|
H00055 | Laryngeal cancer |
P04637
(related)
P04637 (marker) |
H00881 | Li-Fraumeni syndrome |
P04637
(related)
|
H01007 | Choroid plexus papilloma |
P04637
(related)
|
H00021 | Renal cell carcinoma |
P04637
(marker)
|