PCIDB

KNApSAcK Metabolite C00003686

Metabolite

KNApSAcK Entry

id C00003686
Name Cucurbitacin E
CAS RN 18444-66-1
Standard InChI InChI=1S/C32H44O8/c1-17(33)40-27(2,3)13-12-23(36)32(9,39)25-21(35)15-29(6)22-11-10-18-19(14-20(34)26(38)28(18,4)5)31(22,8)24(37)16-30(25,29)7/h10,12-14,19,21-22,25,34-35,39H,11,15-16H2,1-9H3/b13-12+/t19-,21-,22+,25+,29+,30-,31+,32+/m1/s1
Standard InChI (Main Layer) InChI=1S/C32H44O8/c1-17(33)40-27(2,3)13-12-23(36)32(9,39)25-21(35)15-29(6)22-11-10-18-19(14-20(34)26(38)28(18,4)5)31(22,8)24(37)16-30(25,29)7/h10,12-14,19,21-22,25,34-35,39H,11,15-16H2,1-9H3

Cluster

Phytochemical cluster No. 11
KCF-S cluster No. 220

Link

ChEMBL

By standard InChI CHEMBL455056
By standard InChI Main Layer CHEMBL455056

KEGG

By LinkDB C08797

CTD

By CAS RN C102326

Human Protein / Gene in interaction

3 ChEMBL Protein in interactions

accession description class description compound assay ID (# of activities) # of diseases
(OMIM / KEGG)
P20701 Integrin alpha-L Membrane receptor CHEMBL455056 CHEMBL1017447 (1)
0 / 0
P23528 Cofilin-1 Unclassified protein CHEMBL455056 CHEMBL1109057 (1)
0 / 0
P40763 Signal transducer and activator of transcription 3 Transcription Factor CHEMBL455056 CHEMBL1109055 (1) CHEMBL1109056 (2)
1 / 2

Related Disease

Diseases related to proteins in ChEMBL interactions

OMIM (1)

OMIM preferred title UniProt
#147060 Hyper-ige recurrent infection syndrome, autosomal dominant P40763

KEGG DISEASE (2)

KEGG disease name UniProt
H00016 Oral cancer P40763 (related)
H00107 Other well-defined immunodeficiency syndromes P40763 (related)