PCIDB

KNApSAcK Metabolite C00037744

Metabolite

KNApSAcK Entry

id C00037744
Name Rocaglamide
CAS RN 84573-16-0
Standard InChI InChI=1S/C29H31NO7/c1-30(2)27(32)23-24(17-9-7-6-8-10-17)29(18-11-13-19(34-3)14-12-18)28(33,26(23)31)25-21(36-5)15-20(35-4)16-22(25)37-29/h6-16,23-24,26,31,33H,1-5H3/t23-,24-,26-,28+,29+/m1/s1
Standard InChI (Main Layer) InChI=1S/C29H31NO7/c1-30(2)27(32)23-24(17-9-7-6-8-10-17)29(18-11-13-19(34-3)14-12-18)28(33,26(23)31)25-21(36-5)15-20(35-4)16-22(25)37-29/h6-16,23-24,26,31,33H,1-5H3

Cluster

Phytochemical cluster
KCF-S cluster No. 449

Link

ChEMBL

By standard InChI CHEMBL438139
By standard InChI Main Layer CHEMBL438139 CHEMBL601614

KEGG

By LinkDB

CTD

By CAS RN C107772

Species

Summary

Plant class

class name count
rosids 2

Family

family name count
Meliaceae 2

List (2)

* NCBI
KNApSAcK organism *ID *family *plant class *kingdom
Aglaia basiphylla 306494 Meliaceae rosids Viridiplantae
Aglaia elliptifolia 201006 Meliaceae rosids Viridiplantae

Human Protein / Gene in interaction

9 ChEMBL Protein in interactions

accession description class description compound assay ID (# of activities) # of diseases
(OMIM / KEGG)
Q99700 Ataxin-2 Unclassified protein CHEMBL438139 CHEMBL2114784 (1)
1 / 1
P37840 Alpha-synuclein Unclassified protein CHEMBL438139 CHEMBL2354282 (1)
4 / 2
O75496 Geminin Unclassified protein CHEMBL438139 CHEMBL2114843 (1) CHEMBL2114780 (1)
0 / 0
Q04206 Transcription factor p65 Transcription Factor CHEMBL438139 CHEMBL1100043 (1) CHEMBL1109182 (1)
CHEMBL1785171 (1) CHEMBL1804152 (1)
CHEMBL2341058 (1)
0 / 0
P19838 Nuclear factor NF-kappa-B p105 subunit Transcription Factor CHEMBL438139 CHEMBL1100041 (1) CHEMBL1108521 (1)
CHEMBL1109181 (1)
0 / 0
Q16236 Nuclear factor erythroid 2-related factor 2 Unclassified protein CHEMBL438139 CHEMBL1738184 (1)
0 / 0
O75874 Isocitrate dehydrogenase [NADP] cytoplasmic Enzyme CHEMBL438139 CHEMBL2354311 (1)
1 / 0
P01215 Glycoprotein hormones alpha chain Unclassified protein CHEMBL438139 CHEMBL2114913 (1)
0 / 3
Q13148 TAR DNA-binding protein 43 Unclassified protein CHEMBL438139 CHEMBL2354287 (1)
1 / 1

Related Disease

Diseases related to proteins in ChEMBL interactions

OMIM (7)

OMIM preferred title UniProt
#612069 Amyotrophic lateral sclerosis 10, with or without frontotemporal dementia; als10 Q13148
#127750 Dementia, lewy body; dlb P37840
#137800 Glioma susceptibility 1; glm1 O75874
#168601 Parkinson disease 1, autosomal dominant; park1 P37840
#605543 Parkinson disease 4, autosomal dominant; park4 P37840
#168600 Parkinson disease, late-onset; pd P37840
#183090 Spinocerebellar ataxia 2; sca2 Q99700

KEGG DISEASE (7)

KEGG disease name UniProt
H00081 Hashimoto's thyroiditis P01215 (marker)
H00082 Graves' disease P01215 (marker)
H00250 Congenital nongoitrous hypothyroidism (CHNG) P01215 (marker)
H00057 Parkinson's disease (PD) P37840 (related)
H00066 Lewy body dementia (LBD) P37840 (related)
H00058 Amyotrophic lateral sclerosis (ALS) Q13148 (related)
H00063 Spinocerebellar ataxia (SCA) Q99700 (related)