KNApSAcK Metabolite C00003821
Metabolite
KNApSAcK Entry
| id | C00003821 |
|---|---|
| Name | 5,7,4'-Trimethoxyflavone / Apigenin 5,7,4'-trimethyl ether |
| CAS RN | 5631-70-9 |
| Standard InChI | InChI=1S/C18H16O5/c1-20-12-6-4-11(5-7-12)15-10-14(19)18-16(22-3)8-13(21-2)9-17(18)23-15/h4-10H,1-3H3 |
| Standard InChI (Main Layer) | InChI=1S/C18H16O5/c1-20-12-6-4-11(5-7-12)15-10-14(19)18-16(22-3)8-13(21-2)9-17(18)23-15/h4-10H,1-3H3 |
Cluster
| Phytochemical cluster | No. 15 |
|---|---|
| KCF-S cluster | No. 35 |
Link
ChEMBL
| By standard InChI | CHEMBL1087720 |
|---|---|
| By standard InChI Main Layer | CHEMBL1087720 |
KEGG
| By LinkDB |
|---|
CTD
| By CAS RN | C103112 |
|---|
Species
Summary
Plant class
| class name | count |
|---|---|
| rosids | 2 |
| Liliopsida | 2 |
| asterids | 1 |
Family
| family name | count |
|---|---|
| Zingiberaceae | 2 |
| Clusiaceae | 1 |
| Lamiaceae | 1 |
| Rutaceae | 1 |
List (5)
* NCBI
| KNApSAcK organism | *ID | *family | *plant class | *kingdom |
|---|---|---|---|---|
| Boesenbergia pandurata | 97724 | Zingiberaceae | Liliopsida | Viridiplantae |
| Citrus reticulata | 85571 | Rutaceae | rosids | Viridiplantae |
| Garcinia kola | 469930 | Clusiaceae | rosids | Viridiplantae |
| Kaempferia parviflora | 97751 | Zingiberaceae | Liliopsida | Viridiplantae |
| Orthosiphon spicatus | 204150 | Lamiaceae | asterids | Viridiplantae |
Human Protein / Gene in interaction
1 ChEMBL Protein in interactions
| accession | description | class description | compound | assay ID (# of activities) |
# of diseases
(OMIM / KEGG) |
|---|---|---|---|---|---|
| P08183 | Multidrug resistance protein 1 | drug | CHEMBL1087720 |
CHEMBL2076249
(1)
|
1 / 0 |
CTD interaction (1)
| compound | gene | gene name | gene description | interaction | interaction type | form |
reference
pmid |
|---|---|---|---|---|---|---|---|
| C103112 | 1545 |
CYP1B1
CP1B CYPIB1 GLC3A P4501B1 |
cytochrome P450, family 1, subfamily B, polypeptide 1 (EC:1.14.14.1) | 5,7,4'-trimethylapigenin results in decreased expression of CYP1B1 mRNA |
decreases expression
|
mRNA |
17637178
|