KNApSAcK Metabolite C00045115
Metabolite
KNApSAcK Entry
| id | C00045115 |
|---|---|
| Name | trans-beta-Apo-8'-carotenal |
| CAS RN | 1107-26-2 |
| Standard InChI | InChI=1S/C30H40O/c1-24(13-8-9-14-25(2)16-11-18-27(4)23-31)15-10-17-26(3)20-21-29-28(5)19-12-22-30(29,6)7/h8-11,13-18,20-21,23H,12,19,22H2,1-7H3/b9-8+,15-10+,16-11+,21-20+,24-13+,25-14+,26-17+,27-18+ |
| Standard InChI (Main Layer) | InChI=1S/C30H40O/c1-24(13-8-9-14-25(2)16-11-18-27(4)23-31)15-10-17-26(3)20-21-29-28(5)19-12-22-30(29,6)7/h8-11,13-18,20-21,23H,12,19,22H2,1-7H3 |
Cluster
| Phytochemical cluster | |
|---|---|
| KCF-S cluster | No. 747 |
Link
ChEMBL
| By standard InChI | |
|---|---|
| By standard InChI Main Layer |
KEGG
| By LinkDB | C19728 |
|---|
CTD
| By CAS RN | C004984 |
|---|
Species
Summary
Plant class
| class name | count |
|---|---|
| Liliopsida | 1 |
Family
| family name | count |
|---|---|
| Asparagaceae | 1 |
List (1)
* NCBI
| KNApSAcK organism | *ID | *family | *plant class | *kingdom |
|---|---|---|---|---|
| Dracaena draco | 100532 | Asparagaceae | Liliopsida | Viridiplantae |
Human Protein / Gene in interaction
CTD interaction (82)
| compound | gene | gene name | gene description | interaction | interaction type | form |
reference
pmid |
|---|---|---|---|---|---|---|---|
| C004984 | 34 |
ACADM
ACAD1 MCAD MCADH |
acyl-CoA dehydrogenase, C-4 to C-12 straight chain (EC:1.3.8.7) | apocarotenal results in increased expression of ACADM mRNA |
increases expression
|
mRNA |
17034753
|
| C004984 | 124 |
ADH1A
ADH1 |
alcohol dehydrogenase 1A (class I), alpha polypeptide (EC:1.1.1.1) | apocarotenal results in increased expression of ADH1A mRNA |
increases expression
|
mRNA |
17034753
|
| C004984 | 128 |
ADH5
ADH-3 ADHX FALDH FDH GSH-FDH GSNOR |
alcohol dehydrogenase 5 (class III), chi polypeptide (EC:1.1.1.1 1.1.1.284) | apocarotenal results in increased expression of ADH5 mRNA |
increases expression
|
mRNA |
17034753
|
| C004984 | 219 |
ALDH1B1
ALDH5 ALDHX |
aldehyde dehydrogenase 1 family, member B1 (EC:1.2.1.3) | apocarotenal results in decreased expression of ALDH1B1 mRNA |
decreases expression
|
mRNA |
17034753
|
| C004984 | 221 |
ALDH3B1
ALDH4 ALDH7 |
aldehyde dehydrogenase 3 family, member B1 (EC:1.2.1.5) | apocarotenal results in decreased expression of ALDH3B1 mRNA |
decreases expression
|
mRNA |
17034753
|
| C004984 | 8659 |
ALDH4A1
ALDH4 P5CD P5CDh |
aldehyde dehydrogenase 4 family, member A1 (EC:1.2.1.88) | apocarotenal results in decreased expression of ALDH4A1 mRNA |
decreases expression
|
mRNA |
17034753
|
| C004984 | 287 |
ANK2
ANK-2 LQT4 brank-2 |
ankyrin 2, neuronal | apocarotenal results in increased expression of ANK2 mRNA |
increases expression
|
mRNA |
17034753
|
| C004984 | 288 |
ANK3
ANKYRIN-G MRT37 |
ankyrin 3, node of Ranvier (ankyrin G) | apocarotenal results in increased expression of ANK3 mRNA |
increases expression
|
mRNA |
17034753
|
| C004984 | 427 |
ASAH1
AC ACDase ASAH PHP PHP32 SMAPME |
N-acylsphingosine amidohydrolase (acid ceramidase) 1 (EC:3.5.1.23) | apocarotenal results in increased expression of ASAH1 mRNA |
increases expression
|
mRNA |
17034753
|
| C004984 | 51665 |
ASB1
ASB-1 |
ankyrin repeat and SOCS box containing 1 | apocarotenal results in increased expression of ASB1 mRNA |
increases expression
|
mRNA |
17034753
|
| C004984 | 140462 |
ASB9
|
ankyrin repeat and SOCS box containing 9 | apocarotenal results in increased expression of ASB9 mRNA |
increases expression
|
mRNA |
17034753
|
| C004984 | 581 |
BAX
BCL2L4 |
BCL2-associated X protein | apocarotenal results in decreased expression of BAX mRNA |
decreases expression
|
mRNA |
17034753
|
| C004984 | 9994 |
CASP8AP2
CED-4 FLASH RIP25 |
caspase 8 associated protein 2 | apocarotenal results in increased expression of CASP8AP2 mRNA |
increases expression
|
mRNA |
17034753
|
| C004984 | 999 |
CDH1
Arc-1 CD324 CDHE ECAD LCAM UVO |
cadherin 1, type 1, E-cadherin (epithelial) | apocarotenal results in increased expression of CDH1 mRNA |
increases expression
|
mRNA |
17034753
|
| C004984 | 9071 |
CLDN10
CPETRL3 OSP-L |
claudin 10 | apocarotenal results in increased expression of CLDN10 mRNA |
increases expression
|
mRNA |
17034753
|
| C004984 | 51208 |
CLDN18
SFTA5 SFTPJ |
claudin 18 | apocarotenal results in increased expression of CLDN18 mRNA |
increases expression
|
mRNA |
17034753
|
| C004984 | 1277 |
COL1A1
OI4 |
collagen, type I, alpha 1 | apocarotenal results in decreased expression of COL1A1 mRNA |
decreases expression
|
mRNA |
17034753
|
| C004984 | 1282 |
COL4A1
HANAC ICH POREN1 arresten |
collagen, type IV, alpha 1 | apocarotenal results in decreased expression of COL4A1 mRNA |
decreases expression
|
mRNA |
17034753
|
| C004984 | 1284 |
COL4A2
ICH POREN2 |
collagen, type IV, alpha 2 | apocarotenal results in decreased expression of COL4A2 mRNA |
decreases expression
|
mRNA |
17034753
|
| C004984 | 1382 |
CRABP2
CRABP-II RBP6 |
cellular retinoic acid binding protein 2 | apocarotenal results in decreased expression of CRABP2 mRNA |
decreases expression
|
mRNA |
17034753
|
| C004984 | 1508 |
CTSB
APPS CPSB |
cathepsin B (EC:3.4.22.1) | apocarotenal results in decreased expression of CTSB mRNA |
decreases expression
|
mRNA |
17034753
|
| C004984 | 6387 |
CXCL12
IRH PBSF SCYB12 SDF1 TLSF TPAR1 SDF1A SDF1B |
chemokine (C-X-C motif) ligand 12 | apocarotenal results in increased expression of CXCL12 mRNA |
increases expression
|
mRNA |
17034753
|
| C004984 | 6372 |
CXCL6
CKA-3 GCP-2 GCP2 SCYB6 |
chemokine (C-X-C motif) ligand 6 | apocarotenal results in increased expression of CXCL6 mRNA |
increases expression
|
mRNA |
17034753
|
| C004984 | 4283 |
CXCL9
CMK Humig MIG SCYB9 crg-10 |
chemokine (C-X-C motif) ligand 9 | apocarotenal results in increased expression of CXCL9 mRNA |
increases expression
|
mRNA |
17034753
|
| C004984 | 7852 |
CXCR4
CD184 D2S201E FB22 HM89 HSY3RR LAP3 LCR1 LESTR NPY3R NPYR NPYRL NPYY3R WHIM |
chemokine (C-X-C motif) receptor 4 | apocarotenal results in increased expression of CXCR4 mRNA |
increases expression
|
mRNA |
17034753
|
| C004984 | 1559 |
CYP2C9
CPC9 CYP2C CYP2C10 CYPIIC9 P450IIC9 |
cytochrome P450, family 2, subfamily C, polypeptide 9 (EC:1.14.13.48 1.14.13.49 1.14.13.80) | apocarotenal results in increased expression of CYP2C9 mRNA |
increases expression
|
mRNA |
17034753
|
| C004984 | 1746 |
DLX2
TES-1 TES1 |
distal-less homeobox 2 | apocarotenal results in increased expression of DLX2 mRNA |
increases expression
|
mRNA |
17034753
|
| C004984 | 1748 |
DLX4
BP1 DLX7 DLX8 DLX9 |
distal-less homeobox 4 | apocarotenal results in increased expression of DLX4 mRNA |
increases expression
|
mRNA |
17034753
|
| C004984 | 2068 |
ERCC2
COFS2 EM9 TTD XPD |
excision repair cross-complementing rodent repair deficiency, complementation group 2 (EC:3.6.4.12) | apocarotenal results in decreased expression of ERCC2 mRNA |
decreases expression
|
mRNA |
17034753
|
| C004984 | 2113 |
ETS1
ETS-1 EWSR2 |
v-ets avian erythroblastosis virus E26 oncogene homolog 1 | apocarotenal results in decreased expression of ETS1 mRNA |
decreases expression
|
mRNA |
17034753
|
| C004984 | 355 |
FAS
ALPS1A APO-1 APT1 CD95 FAS1 FASTM TNFRSF6 |
Fas cell surface death receptor | apocarotenal results in increased expression of FAS mRNA |
increases expression
|
mRNA |
17034753
|
| C004984 | 2194 |
FASN
FAS OA-519 SDR27X1 |
fatty acid synthase (EC:2.3.1.85 2.3.1.38 2.3.1.39 2.3.1.41 3.1.2.14 4.2.1.59 1.1.1.100 1.3.1.39) | apocarotenal results in decreased expression of FASN mRNA |
decreases expression
|
mRNA |
17034753
|
| C004984 | 2627 |
GATA6
|
GATA binding protein 6 | apocarotenal results in increased expression of GATA6 mRNA |
increases expression
|
mRNA |
17034753
|
| C004984 | 2633 |
GBP1
|
guanylate binding protein 1, interferon-inducible | apocarotenal results in increased expression of GBP1 mRNA |
increases expression
|
mRNA |
17034753
|
| C004984 | 81025 |
GJA9
CX58 CX59 GJA10 |
gap junction protein, alpha 9, 59kDa | apocarotenal results in increased expression of GJA9 mRNA |
increases expression
|
mRNA |
17034753
|
| C004984 | 373156 |
GSTK1
GST GST_13-13 GST13 GST13-13 GSTK1-1 hGSTK1 |
glutathione S-transferase kappa 1 (EC:2.5.1.18) | apocarotenal results in decreased expression of GSTK1 mRNA |
decreases expression
|
mRNA |
17034753
|
| C004984 | 2946 |
GSTM2
GST4 GSTM GSTM2-2 GTHMUS |
glutathione S-transferase mu 2 (muscle) (EC:2.5.1.18) | apocarotenal results in decreased expression of GSTM2 mRNA |
decreases expression
|
mRNA |
17034753
|
| C004984 | 2948 |
GSTM4
GSTM4-4 GTM4 |
glutathione S-transferase mu 4 (EC:2.5.1.18) | apocarotenal results in decreased expression of GSTM4 mRNA |
decreases expression
|
mRNA |
17034753
|
| C004984 | 2949 |
GSTM5
GSTM5-5 GTM5 |
glutathione S-transferase mu 5 (EC:2.5.1.18) | apocarotenal results in increased expression of GSTM5 mRNA |
increases expression
|
mRNA |
17034753
|
| C004984 | 2954 |
GSTZ1
GSTZ1-1 MAAI MAI |
glutathione S-transferase zeta 1 (EC:2.5.1.18 5.2.1.2) | apocarotenal results in decreased expression of GSTZ1 mRNA |
decreases expression
|
mRNA |
17034753
|
| C004984 | 3204 |
HOXA7
ANTP HOX1 HOX1.1 HOX1A |
homeobox A7 | apocarotenal results in increased expression of HOXA7 mRNA |
increases expression
|
mRNA |
17034753
|
| C004984 | 3216 |
HOXB6
HOX2 HOX2B HU-2 Hox-2.2 |
homeobox B6 | apocarotenal results in increased expression of HOXB6 mRNA |
increases expression
|
mRNA |
17034753
|
| C004984 | 3226 |
HOXC10
HOX3I |
homeobox C10 | apocarotenal results in increased expression of HOXC10 mRNA |
increases expression
|
mRNA |
17034753
|
| C004984 | 3448 |
IFNA14
IFN-alphaH LEIF2H |
interferon, alpha 14 | apocarotenal results in increased expression of IFNA14 mRNA |
increases expression
|
mRNA |
17034753
|
| C004984 | 3449 |
IFNA16
IFN-alphaO |
interferon, alpha 16 | apocarotenal results in increased expression of IFNA16 mRNA |
increases expression
|
mRNA |
17034753
|
| C004984 | 3451 |
IFNA17
IFN-alphaI IFNA INFA LEIF2C1 |
interferon, alpha 17 | apocarotenal results in increased expression of IFNA17 mRNA |
increases expression
|
mRNA |
17034753
|
| C004984 | 3442 |
IFNA5
IFN-alpha-5 IFN-alphaG INA5 INFA5 leIF_G |
interferon, alpha 5 | apocarotenal results in increased expression of IFNA5 mRNA |
increases expression
|
mRNA |
17034753
|
| C004984 | 3394 |
IRF8
H-ICSBP ICSBP ICSBP1 IRF-8 |
interferon regulatory factor 8 | apocarotenal results in increased expression of IRF8 mRNA |
increases expression
|
mRNA |
17034753
|
| C004984 | 50805 |
IRX4
IRXA3 |
iroquois homeobox 4 | apocarotenal results in decreased expression of IRX4 mRNA |
decreases expression
|
mRNA |
17034753
|
| C004984 | 3691 |
ITGB4
CD104 |
integrin, beta 4 | apocarotenal results in decreased expression of ITGB4 mRNA |
decreases expression
|
mRNA |
17034753
|
| C004984 | 3713 |
IVL
|
involucrin | apocarotenal results in increased expression of IVL mRNA |
increases expression
|
mRNA |
17034753
|
| C004984 | 3872 |
KRT17
K17 PC PC2 PCHC1 |
keratin 17 | apocarotenal results in decreased expression of KRT17 mRNA |
decreases expression
|
mRNA |
17034753
|
| C004984 | 3849 |
KRT2
CK-2e K2e KRT2A KRT2E KRTE |
keratin 2 | apocarotenal results in increased expression of KRT2 mRNA |
increases expression
|
mRNA |
17034753
|
| C004984 | 3855 |
KRT7
CK7 K2C7 K7 SCL |
keratin 7 | apocarotenal affects the expression of KRT7 mRNA |
affects expression
|
mRNA |
17034753
|
| C004984 | 8022 |
LHX3
CPHD3 LIM3 M2-LHX3 |
LIM homeobox 3 | apocarotenal results in increased expression of LHX3 mRNA |
increases expression
|
mRNA |
17034753
|
| C004984 | 4170 |
MCL1
BCL2L3 EAT MCL1-ES MCL1L MCL1S Mcl-1 TM bcl2-L-3 mcl1/EAT |
myeloid cell leukemia sequence 1 (BCL2-related) | apocarotenal affects the expression of MCL1 mRNA |
affects expression
|
mRNA |
17034753
|
| C004984 | 4212 |
MEIS2
HsT18361 MRG1 |
Meis homeobox 2 | apocarotenal results in increased expression of MEIS2 mRNA |
increases expression
|
mRNA |
17034753
|
| C004984 | 4222 |
MEOX1
KFS2 MOX1 |
mesenchyme homeobox 1 | apocarotenal results in increased expression of MEOX1 mRNA |
increases expression
|
mRNA |
17034753
|
| C004984 | 3110 |
MNX1
HB9 HLXB9 HOXHB9 SCRA1 |
motor neuron and pancreas homeobox 1 | apocarotenal results in increased expression of MNX1 mRNA |
increases expression
|
mRNA |
17034753
|
| C004984 | 4439 |
MSH5
G7 MUTSH5 NG23 |
mutS homolog 5 | apocarotenal results in increased expression of MSH5 mRNA |
increases expression
|
mRNA |
17034753
|
| C004984 | 4586 |
MUC5AC
MUC5 TBM leB |
mucin 5AC, oligomeric mucus/gel-forming | apocarotenal results in increased expression of MUC5AC mRNA |
increases expression
|
mRNA |
17034753
|
| C004984 | 4842 |
NOS1
IHPS1 N-NOS NC-NOS NOS bNOS nNOS |
nitric oxide synthase 1 (neuronal) (EC:1.14.13.39) | apocarotenal results in increased expression of NOS1 mRNA |
increases expression
|
mRNA |
17034753
|
| C004984 | 4973 |
OLR1
CLEC8A LOX1 LOXIN SCARE1 SLOX1 |
oxidized low density lipoprotein (lectin-like) receptor 1 | apocarotenal results in increased expression of OLR1 mRNA |
increases expression
|
mRNA |
17034753
|
| C004984 | 5098 |
PCDHGC3
PC43 PCDH-GAMMA-C3 PCDH2 |
protocadherin gamma subfamily C, 3 | apocarotenal results in increased expression of PCDHGC3 mRNA |
increases expression
|
mRNA |
17034753
|
| C004984 | 5359 |
PLSCR1
MMTRA1B |
phospholipid scramblase 1 | apocarotenal results in increased expression of PLSCR1 mRNA |
increases expression
|
mRNA |
17034753
|
| C004984 | 57048 |
PLSCR3
|
phospholipid scramblase 3 | apocarotenal results in increased expression of PLSCR3 mRNA |
increases expression
|
mRNA |
17034753
|
| C004984 | 57088 |
PLSCR4
TRA1 |
phospholipid scramblase 4 | apocarotenal results in increased expression of PLSCR4 mRNA |
increases expression
|
mRNA |
17034753
|
| C004984 | 10635 |
RAD51AP1
PIR51 |
RAD51 associated protein 1 | apocarotenal results in increased expression of RAD51AP1 mRNA |
increases expression
|
mRNA |
17034753
|
| C004984 | 5892 |
RAD51D
BROVCA4 R51H3 RAD51L3 TRAD |
RAD51 paralog D | apocarotenal results in increased expression of RAD51D mRNA |
increases expression
|
mRNA |
17034753
|
| C004984 | 5914 |
RARA
NR1B1 RAR |
retinoic acid receptor, alpha | apocarotenal results in decreased expression of RARA mRNA |
decreases expression
|
mRNA |
17034753
|
| C004984 | 5915 |
RARB
HAP NR1B2 RRB2 |
retinoic acid receptor, beta | apocarotenal results in increased expression of RARB mRNA |
increases expression
|
mRNA |
17034753
|
| C004984 | 5918 |
RARRES1
LXNL TIG1 |
retinoic acid receptor responder (tazarotene induced) 1 | apocarotenal results in increased expression of RARRES1 mRNA |
increases expression
|
mRNA |
17034753
|
| C004984 | 5920 |
RARRES3
HRASLS4 HRSL4 PLA1/2-3 RIG1 TIG3 |
retinoic acid receptor responder (tazarotene induced) 3 | apocarotenal results in decreased expression of RARRES3 mRNA |
decreases expression
|
mRNA |
17034753
|
| C004984 | 4990 |
SIX6
MCOPCT2 OPTX2 Six9 |
SIX homeobox 6 | apocarotenal results in increased expression of SIX6 mRNA |
increases expression
|
mRNA |
17034753
|
| C004984 | 6647 |
SOD1
ALS ALS1 IPOA SOD hSod1 homodimer |
superoxide dismutase 1, soluble (EC:1.15.1.1) | apocarotenal results in decreased expression of SOD1 mRNA |
decreases expression
|
mRNA |
17034753
|
| C004984 | 9517 |
SPTLC2
HSN1C LCB2 LCB2A NSAN1C SPT2 hLCB2a |
serine palmitoyltransferase, long chain base subunit 2 (EC:2.3.1.50) | apocarotenal affects the expression of SPTLC2 mRNA |
affects expression
|
mRNA |
17034753
|
| C004984 | 6720 |
SREBF1
SREBP-1c SREBP1 bHLHd1 |
sterol regulatory element binding transcription factor 1 | apocarotenal results in increased expression of SREBF1 mRNA |
increases expression
|
mRNA |
17034753
|
| C004984 | 7047 |
TGM4
TGP hTGP |
transglutaminase 4 (EC:2.3.2.13) | apocarotenal results in increased expression of TGM4 mRNA |
increases expression
|
mRNA |
17034753
|
| C004984 | 3604 |
TNFRSF9
4-1BB CD137 CDw137 ILA |
tumor necrosis factor receptor superfamily, member 9 | apocarotenal results in increased expression of TNFRSF9 mRNA |
increases expression
|
mRNA |
17034753
|
| C004984 | 8743 |
TNFSF10
APO2L Apo-2L CD253 TL2 TRAIL |
tumor necrosis factor (ligand) superfamily, member 10 | apocarotenal results in increased expression of TNFSF10 mRNA |
increases expression
|
mRNA |
17034753
|
| C004984 | 10190 |
TXNDC9
APACD PHLP3 |
thioredoxin domain containing 9 | apocarotenal results in increased expression of TXNDC9 mRNA |
increases expression
|
mRNA |
17034753
|
| C004984 | 7517 |
XRCC3
CMM6 |
X-ray repair complementing defective repair in Chinese hamster cells 3 | apocarotenal results in increased expression of XRCC3 mRNA |
increases expression
|
mRNA |
17034753
|