PCIDB

KNApSAcK Metabolite C00004655

Metabolite

KNApSAcK Entry

id C00004655
Name Quercetin pentamethyl ether / 3,5,7,3',4'-Pentamethoxyflavone
CAS RN 1247-97-8
Standard InChI InChI=1S/C20H20O7/c1-22-12-9-15(25-4)17-16(10-12)27-19(20(26-5)18(17)21)11-6-7-13(23-2)14(8-11)24-3/h6-10H,1-5H3
Standard InChI (Main Layer) InChI=1S/C20H20O7/c1-22-12-9-15(25-4)17-16(10-12)27-19(20(26-5)18(17)21)11-6-7-13(23-2)14(8-11)24-3/h6-10H,1-5H3

Cluster

Phytochemical cluster No. 15
KCF-S cluster No. 8

Link

ChEMBL

By standard InChI CHEMBL19032
By standard InChI Main Layer CHEMBL19032

KEGG

By LinkDB

CTD

By CAS RN

Human Protein / Gene in interaction

16 ChEMBL Protein in interactions

accession description class description compound assay ID (# of activities) # of diseases
(OMIM / KEGG)
P33527 Multidrug resistance-associated protein 1 drugs CHEMBL19032 CHEMBL2045961 (1)
0 / 0
Q13526 Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 Enzyme CHEMBL19032 CHEMBL1794585 (1)
0 / 0
Q9NR56 Muscleblind-like protein 1 Unclassified protein CHEMBL19032 CHEMBL1614166 (1)
1 / 0
P00352 Retinal dehydrogenase 1 Enzyme CHEMBL19032 CHEMBL1614458 (1)
0 / 0
P17405 Sphingomyelin phosphodiesterase Enzyme CHEMBL19032 CHEMBL1794495 (1)
2 / 2
P39748 Flap endonuclease 1 Enzyme CHEMBL19032 CHEMBL1794486 (1)
0 / 0
P43220 Glucagon-like peptide 1 receptor Glucagon-like peptide receptor CHEMBL19032 CHEMBL2114788 (1)
0 / 0
Q12791 Calcium-activated potassium channel subunit alpha-1 KCNM, KCa1.x CHEMBL19032 CHEMBL767233 (1)
1 / 1
P28482 Mitogen-activated protein kinase 1 Erk CHEMBL19032 CHEMBL1614521 (1) CHEMBL1613808 (1)
0 / 0
Q9UNQ0 ATP-binding cassette sub-family G member 2 ATP binding cassette CHEMBL19032 CHEMBL2045959 (1) CHEMBL2045960 (1)
2 / 0
Q96QE3 ATPase family AAA domain-containing protein 5 Unclassified protein CHEMBL19032 CHEMBL1738588 (1)
0 / 0
P08684 Cytochrome P450 3A4 Cytochrome P450 3A4 CHEMBL19032 CHEMBL1614108 (1) CHEMBL1613886 (1)
0 / 1
B2RXH2 Lysine-specific demethylase 4E Enzyme CHEMBL19032 CHEMBL1613914 (2)
0 / 0
Q9NUW8 Tyrosyl-DNA phosphodiesterase 1 Enzyme CHEMBL19032 CHEMBL1614364 (1)
1 / 1
O00255 Menin Unclassified protein CHEMBL19032 CHEMBL1614257 (1)
2 / 5
Q03164 Histone-lysine N-methyltransferase 2A Enzyme CHEMBL19032 CHEMBL1614257 (1)
1 / 3

Related Disease

Diseases related to proteins in ChEMBL interactions

OMIM (10)

OMIM preferred title UniProt
#614490 Blood group, junior system; jr Q9UNQ0
#609446 Generalized epilepsy and paroxysmal dyskinesia; gepd Q12791
#605130 Hairy elbows, short stature, facial dysmorphism, and developmental delay Q03164
#145000 Hyperparathyroidism 1; hrpt1 O00255
#131100 Multiple endocrine neoplasia, type i; men1 O00255
#160900 Myotonic dystrophy 1; dm1 Q9NR56
#257200 Niemann-pick disease, type a P17405
#607616 Niemann-pick disease, type b P17405
#607250 Spinocerebellar ataxia, autosomal recessive, with axonal neuropathy; scan1 Q9NUW8
#138900 Uric acid concentration, serum, quantitative trait locus 1; uaqtl1 Q9UNQ0

KEGG DISEASE (12)

KEGG disease name UniProt
H00033 Adrenal carcinoma O00255 (related)
H00034 Carcinoid O00255 (related)
H00045 Malignant islet cell carcinoma O00255 (related)
H00246 Primary hyperparathyroidism O00255 (related)
H01102 Pituitary adenomas O00255 (related)
H00036 Osteosarcoma P08684 (marker)
H00137 Niemann-Pick disease (NPD) typeA and B P17405 (related)
H00424 Defects in the degradation of sphingomyelin P17405 (related)
H00001 Acute lymphoblastic leukemia (ALL) (precursor B lymphoblastic leukemia) Q03164 (related)
Q03164 (marker)
H00002 Acute lymphoblastic leukemia (ALL) (precursor T lymphoblastic leukemia) Q03164 (related)
H01258 Generalized epilepsy and paroxysmal dyskinesia (GEPD) Q12791 (related)
H00063 Spinocerebellar ataxia (SCA) Q9NUW8 (related)