PCIDB

KNApSAcK Metabolite C00006104

Metabolite

KNApSAcK Entry

id C00006104
Name 6-C-Galactosylluteolin / 2-(3,4-Dihydroxyphenyl)-6-beta-D-galactopyranosyl-5,7-dihydroxy-4H-1-benzopyran-4-one
CAS RN 113349-18-1
Standard InChI InChI=1S/C21H20O11/c22-6-14-17(27)19(29)20(30)21(32-14)16-11(26)5-13-15(18(16)28)10(25)4-12(31-13)7-1-2-8(23)9(24)3-7/h1-5,14,17,19-24,26-30H,6H2/t14?,17-,19-,20?,21-/m0/s1
Standard InChI (Main Layer) InChI=1S/C21H20O11/c22-6-14-17(27)19(29)20(30)21(32-14)16-11(26)5-13-15(18(16)28)10(25)4-12(31-13)7-1-2-8(23)9(24)3-7/h1-5,14,17,19-24,26-30H,6H2

Cluster

Phytochemical cluster No. 15
KCF-S cluster No. 22

Link

ChEMBL

By standard InChI
By standard InChI Main Layer CHEMBL239559 CHEMBL1302308

KEGG

By LinkDB

CTD

By CAS RN

Species

Summary

Plant class

class name count
Liliopsida 1
rosids 1

Family

family name count
Poaceae 1
Fabaceae 1

List (2)

* NCBI
KNApSAcK organism *ID *family *plant class *kingdom
Muhlenbergia spp. 58090 Poaceae Liliopsida Viridiplantae
Parkinsonia aculeata 58886 Fabaceae rosids Viridiplantae

Human Protein / Gene in interaction

23 ChEMBL Protein in interactions

accession description class description compound assay ID (# of activities) # of diseases
(OMIM / KEGG)
Q9UIF8 Bromodomain adjacent to zinc finger domain protein 2B Unclassified protein CHEMBL1302308 CHEMBL1738312 (1)
0 / 0
P06746 DNA polymerase beta Enzyme CHEMBL1302308 CHEMBL1614079 (1)
0 / 0
P10253 Lysosomal alpha-glucosidase Hydrolase CHEMBL1302308 CHEMBL1614076 (1)
1 / 1
Q13526 Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 Enzyme CHEMBL239559 CHEMBL1302308 CHEMBL1794585 (2)
0 / 0
Q9NR56 Muscleblind-like protein 1 Unclassified protein CHEMBL1302308 CHEMBL1614166 (1)
1 / 0
P39748 Flap endonuclease 1 Enzyme CHEMBL239559 CHEMBL1302308 CHEMBL1794486 (3)
0 / 0
Q9Y253 DNA polymerase eta Enzyme CHEMBL239559 CHEMBL1302308 CHEMBL1794569 (2)
1 / 1
Q9Y468 Lethal(3)malignant brain tumor-like protein 1 Unclassified protein CHEMBL239559 CHEMBL1302308 CHEMBL1614280 (2)
0 / 0
Q96QE3 ATPase family AAA domain-containing protein 5 Unclassified protein CHEMBL239559 CHEMBL1738588 (1)
0 / 0
Q9UNA4 DNA polymerase iota Enzyme CHEMBL239559 CHEMBL1302308 CHEMBL1794483 (3)
0 / 0
O75164 Lysine-specific demethylase 4A Enzyme CHEMBL239559 CHEMBL1302308 CHEMBL1737991 (3)
0 / 0
P27695 DNA-(apurinic or apyrimidinic site) lyase Enzyme CHEMBL239559 CHEMBL1302308 CHEMBL1614466 (1) CHEMBL1614211 (2)
0 / 0
P10636 Microtubule-associated protein tau Unclassified protein CHEMBL1302308 CHEMBL1614421 (1)
4 / 3
Q9UBT6 DNA polymerase kappa Enzyme CHEMBL239559 CHEMBL1302308 CHEMBL1794536 (3)
0 / 0
B2RXH2 Lysine-specific demethylase 4E Enzyme CHEMBL1302308 CHEMBL1613914 (1)
0 / 0
Q9NUW8 Tyrosyl-DNA phosphodiesterase 1 Enzyme CHEMBL239559 CHEMBL1614364 (1)
1 / 1
O00255 Menin Unclassified protein CHEMBL1302308 CHEMBL1614257 (1)
2 / 5
Q03164 Histone-lysine N-methyltransferase 2A Enzyme CHEMBL1302308 CHEMBL1614257 (1)
1 / 3
Q13951 Core-binding factor subunit beta Unclassified protein CHEMBL239559 CHEMBL1613933 (1)
0 / 1
Q01196 Runt-related transcription factor 1 Unclassified protein CHEMBL239559 CHEMBL1613933 (1)
1 / 6
O94925 Glutaminase kidney isoform, mitochondrial Enzyme CHEMBL239559 CHEMBL1302308 CHEMBL2114738 (2)
0 / 0
Q9H0H5 Rac GTPase-activating protein 1 Unclassified protein CHEMBL239559 CHEMBL1302308 CHEMBL2114881 (2)
0 / 0
Q14191 Werner syndrome ATP-dependent helicase Enzyme CHEMBL1302308 CHEMBL2114796 (1)
2 / 1

Related Disease

Diseases related to proteins in ChEMBL interactions

OMIM (14)

OMIM preferred title UniProt
#114500 Colorectal cancer; crc Q14191
#600274 Frontotemporal dementia; ftd P10636
#232300 Glycogen storage disease ii P10253
#605130 Hairy elbows, short stature, facial dysmorphism, and developmental delay Q03164
#145000 Hyperparathyroidism 1; hrpt1 O00255
#131100 Multiple endocrine neoplasia, type i; men1 O00255
#160900 Myotonic dystrophy 1; dm1 Q9NR56
#260540 Parkinson-dementia syndrome P10636
#172700 Pick disease of brain P10636
#601399 Platelet disorder, familial, with associated myeloid malignancy Q01196
#607250 Spinocerebellar ataxia, autosomal recessive, with axonal neuropathy; scan1 Q9NUW8
#601104 Supranuclear palsy, progressive, 1; psnp1 P10636
#277700 Werner syndrome; wrn Q14191
#278750 Xeroderma pigmentosum, variant type; xpv Q9Y253

KEGG DISEASE (17)

KEGG disease name UniProt
H00033 Adrenal carcinoma O00255 (related)
H00034 Carcinoid O00255 (related)
H00045 Malignant islet cell carcinoma O00255 (related)
H00246 Primary hyperparathyroidism O00255 (related)
H01102 Pituitary adenomas O00255 (related)
H00069 Glycogen storage diseases (GSD) P10253 (related)
H00058 Amyotrophic lateral sclerosis (ALS) P10636 (related)
H00077 Progressive supranuclear palsy (PSP) P10636 (related)
H00078 Frontotemporal lobar degeneration (FTLD) P10636 (related)
H00001 Acute lymphoblastic leukemia (ALL) (precursor B lymphoblastic leukemia) Q01196 (related)
Q01196 (marker)
Q03164 (related)
Q03164 (marker)
H00003 Acute myeloid leukemia (AML) Q01196 (related)
Q01196 (marker)
Q13951 (marker)
H00004 Chronic myeloid leukemia (CML) Q01196 (related)
H00978 Thrombocytopenia (THC) Q01196 (related)
H00002 Acute lymphoblastic leukemia (ALL) (precursor T lymphoblastic leukemia) Q03164 (related)
H00296 Defects in RecQ helicases Q14191 (related)
H00063 Spinocerebellar ataxia (SCA) Q9NUW8 (related)
H00403 Disorders of nucleotide excision repair Q9Y253 (related)