PCIDB

KNApSAcK Metabolite C00000677

Metabolite

KNApSAcK Entry

id C00000677
Name Distylin / Dihydroquercetin / (2R,3R)-Taxifolin
CAS RN 480-18-2
Standard InChI InChI=1S/C15H12O7/c16-7-4-10(19)12-11(5-7)22-15(14(21)13(12)20)6-1-2-8(17)9(18)3-6/h1-5,14-19,21H/t14-,15+/m0/s1
Standard InChI (Main Layer) InChI=1S/C15H12O7/c16-7-4-10(19)12-11(5-7)22-15(14(21)13(12)20)6-1-2-8(17)9(18)3-6/h1-5,14-19,21H

Cluster

Phytochemical cluster No. 14
KCF-S cluster No. 42

Link

ChEMBL

By standard InChI CHEMBL66
By standard InChI Main Layer CHEMBL66 CHEMBL9249 CHEMBL337309 CHEMBL1492383

KEGG

By LinkDB C01617

CTD

By CAS RN C003377

Species

Summary

Plant class

class name count
rosids 19
asterids 7
Spermatophyta 5
Magnoliophyta 3
eudicotyledons 3
Liliopsida 3

Family (Top 10)

family name count
Fabaceae 7
Pinaceae 4
Asteraceae 2
Annonaceae 2
Rhamnaceae 2
Anacardiaceae 2
Orchidaceae 2
Brassicaceae 2
Geraniaceae 1
Xanthoceraceae 1

List (41)

* NCBI
KNApSAcK organism *ID *family *plant class *kingdom
Acacia carnei 3808 Fabaceae rosids Viridiplantae
Acacia catechu 138017 Fabaceae rosids Viridiplantae
Anaxagorea luzonensis A.GRAY 235716 Annonaceae Magnoliophyta Viridiplantae
Anthemis altissima 99027 Asteraceae asterids Viridiplantae
Arabidopsis thaliana 3702 Brassicaceae rosids Viridiplantae
Brassica carinata Y line 3705 Brassicaceae rosids Viridiplantae
Camellia sinensis 4442 Theaceae asterids Viridiplantae
Cedrus deodara 3322 Pinaceae Spermatophyta Viridiplantae
Cleistopholis glauca 306911 Annonaceae Magnoliophyta Viridiplantae
Colophospermum mopane 162715 Fabaceae rosids Viridiplantae
Crotalaria assamica 671522 Fabaceae rosids Viridiplantae
Crotalaria pallida 3830 Fabaceae rosids Viridiplantae
Dillenia spp. 4377 Dilleniaceae eudicotyledons Viridiplantae
Equsetum arvense
Genista corsica 319660 Fabaceae rosids Viridiplantae
Gongora quinquenervis 125119 Orchidaceae Liliopsida Viridiplantae
Juglans mandshurica 91218 Juglandaceae rosids Viridiplantae
Kadsura heteroclita 124781 Schisandraceae Magnoliophyta Viridiplantae
Larix decidua 71402 Pinaceae Spermatophyta Viridiplantae
Lippia sidoides 320357 Verbenaceae asterids Viridiplantae
Melanorrhoea spp. 4011 Anacardiaceae rosids Viridiplantae
Neomoorea wallisii 125148 Orchidaceae Liliopsida Viridiplantae
Nothofagus spp. 26779 Nothofagaceae rosids Viridiplantae
Opuntia ficus-indica var.saboten 106975 Cactaceae eudicotyledons Viridiplantae
Pelargonium reniforme 59871 Geraniaceae rosids Viridiplantae
Picea obovata 331118 Pinaceae Spermatophyta Viridiplantae
Pistacia chinensis 289741 Anacardiaceae rosids Viridiplantae
Platycodon grandiflorum 94286 Campanulaceae asterids Viridiplantae
Polygala caudata 4275 Polygalaceae rosids Viridiplantae
Polygonum nodosum 488004 Polygonaceae eudicotyledons Viridiplantae
Pseudotsuga menziesii 3357 Pinaceae Spermatophyta Viridiplantae
Pulicaria undulata 119186 Asteraceae asterids Viridiplantae
Rhamnus disperma 3609 Rhamnaceae rosids Viridiplantae
Rhamnus pallasii 3609 Rhamnaceae rosids Viridiplantae
Rhododendron spp. 4346 Ericaceae asterids Viridiplantae
Salix caprea 172267 Salicaceae rosids Viridiplantae
Smilax glabra 703614 Smilacaceae Liliopsida Viridiplantae
Spatholobus suberectus Dunn 455371 Fabaceae rosids Viridiplantae
Taxus mairei 120273 Taxaceae Spermatophyta Viridiplantae
Thymus vulgaris 49992 Lamiaceae asterids Viridiplantae
Xanthoceras sorbifolia 99658 Xanthoceraceae rosids Viridiplantae

Human Protein / Gene in interaction

65 ChEMBL Protein in interactions

accession description class description compound assay ID (# of activities) # of diseases
(OMIM / KEGG)
P10635 Cytochrome P450 2D6 Cytochrome P450 2D6 CHEMBL9249 CHEMBL1741321 (1)
1 / 0
Q16637 Survival motor neuron protein Unclassified protein CHEMBL337309 CHEMBL1613842 (1)
4 / 2
Q9UIF8 Bromodomain adjacent to zinc finger domain protein 2B Unclassified protein CHEMBL66 CHEMBL1738312 (2)
0 / 0
P49798 Regulator of G-protein signaling 4 Unclassified protein CHEMBL337309 CHEMBL1794499 (1)
2 / 0
P09917 Arachidonate 5-lipoxygenase Oxidoreductase CHEMBL66 CHEMBL905752 (1)
0 / 0
P21728 D(1A) dopamine receptor Dopamine receptor CHEMBL337309 CHEMBL1738091 (1)
0 / 0
P33765 Adenosine receptor A3 Adenosine receptor CHEMBL337309 CHEMBL638578 (1) CHEMBL649050 (1)
0 / 0
P06746 DNA polymerase beta Enzyme CHEMBL66 CHEMBL337309 CHEMBL1614079 (3)
0 / 0
P10253 Lysosomal alpha-glucosidase Hydrolase CHEMBL66 CHEMBL1614076 (2)
1 / 1
P39900 Macrophage metalloelastase M10A CHEMBL337309 CHEMBL2051216 (1) CHEMBL2051222 (1)
0 / 0
P14780 Matrix metalloproteinase-9 M10A CHEMBL337309 CHEMBL2051215 (1) CHEMBL2051221 (1)
2 / 2
Q13526 Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 Enzyme CHEMBL337309 CHEMBL1738600 (1)
0 / 0
P28907 ADP-ribosyl cyclase 1 Enzyme CHEMBL337309 CHEMBL1799589 (1)
0 / 1
P47989 Xanthine dehydrogenase/oxidase Oxidoreductase CHEMBL337309 CHEMBL1023248 (1)
1 / 1
P11712 Cytochrome P450 2C9 Cytochrome P450 2C9 CHEMBL9249 CHEMBL1741325 (1)
0 / 1
P54132 Bloom syndrome protein Enzyme CHEMBL337309 CHEMBL1614522 (1) CHEMBL1614067 (1)
1 / 2
P41145 Kappa-type opioid receptor Opioid receptor CHEMBL337309 CHEMBL926465 (1)
0 / 0
P36888 Receptor-type tyrosine-protein kinase FLT3 Pdgfr CHEMBL337309 CHEMBL2342404 (1)
1 / 1
Q16665 Hypoxia-inducible factor 1-alpha Transcription Factor CHEMBL9249 CHEMBL1614456 (1) CHEMBL1613803 (1)
0 / 0
P39748 Flap endonuclease 1 Enzyme CHEMBL66 CHEMBL337309 CHEMBL1613922 (1) CHEMBL1794486 (2)
0 / 0
O75496 Geminin Unclassified protein CHEMBL66 CHEMBL337309 CHEMBL1613941 (1) CHEMBL2114780 (1)
0 / 0
P41143 Delta-type opioid receptor Opioid receptor CHEMBL337309 CHEMBL926467 (1)
0 / 0
P03956 Interstitial collagenase M10A CHEMBL337309 CHEMBL2051212 (1)
0 / 1
Q9Y253 DNA polymerase eta Enzyme CHEMBL337309 CHEMBL1794569 (1)
1 / 1
P83916 Chromobox protein homolog 1 Unclassified protein CHEMBL337309 CHEMBL1738610 (1)
0 / 0
P11021 78 kDa glucose-regulated protein Unclassified protein CHEMBL337309 CHEMBL1963893 (1)
0 / 0
P45452 Collagenase 3 M10A CHEMBL337309 CHEMBL2051217 (1) CHEMBL2051223 (1)
1 / 1
P18054 Arachidonate 12-lipoxygenase, 12S-type Enzyme CHEMBL9249 CHEMBL1614252 (1)
2 / 0
P28482 Mitogen-activated protein kinase 1 Erk CHEMBL9249 CHEMBL1613808 (1)
0 / 0
P56817 Beta-secretase 1 A1A CHEMBL66 CHEMBL653507 (2)
0 / 0
P05177 Cytochrome P450 1A2 Cytochrome P450 1A2 CHEMBL9249 CHEMBL1741322 (1)
0 / 0
P08253 72 kDa type IV collagenase M10A CHEMBL337309 CHEMBL2051213 (1) CHEMBL2051219 (1)
1 / 3
Q99714 3-hydroxyacyl-CoA dehydrogenase type-2 Enzyme CHEMBL9249 CHEMBL1614227 (1)
3 / 3
Q92887 Canalicular multispecific organic anion transporter 1 Unclassified protein CHEMBL337309 CHEMBL1006005 (1)
1 / 1
P15428 15-hydroxyprostaglandin dehydrogenase [NAD(+)] Enzyme CHEMBL337309 CHEMBL1614038 (1)
2 / 2
Q01453 Peripheral myelin protein 22 Unclassified protein CHEMBL337309 CHEMBL1614171 (1)
5 / 2
P35372 Mu-type opioid receptor Opioid receptor CHEMBL337309 CHEMBL926466 (1)
0 / 0
P19838 Nuclear factor NF-kappa-B p105 subunit Transcription Factor CHEMBL9249 CHEMBL1614274 (1) CHEMBL1613823 (1)
0 / 0
P16050 Arachidonate 15-lipoxygenase Enzyme CHEMBL9249 CHEMBL1614240 (1)
0 / 0
P33261 Cytochrome P450 2C19 Cytochrome P450 2C19 CHEMBL9249 CHEMBL1741323 (1)
1 / 1
P08684 Cytochrome P450 3A4 Cytochrome P450 3A4 CHEMBL9249 CHEMBL337309 CHEMBL1614108 (2) CHEMBL1613886 (2)
CHEMBL1741324 (1)
0 / 1
Q9UNA4 DNA polymerase iota Enzyme CHEMBL66 CHEMBL337309 CHEMBL1794483 (2)
0 / 0
P27695 DNA-(apurinic or apyrimidinic site) lyase Enzyme CHEMBL66 CHEMBL337309 CHEMBL1492383 CHEMBL1614211 (5)
0 / 0
P10636 Microtubule-associated protein tau Unclassified protein CHEMBL66 CHEMBL337309 CHEMBL1614421 (3)
4 / 3
P08254 Stromelysin-1 M10A CHEMBL337309 CHEMBL2051214 (1) CHEMBL2051220 (1)
1 / 0
Q9UBT6 DNA polymerase kappa Enzyme CHEMBL66 CHEMBL337309 CHEMBL1492383 CHEMBL1794536 (4)
0 / 0
P24298 Alanine aminotransferase 1 Enzyme CHEMBL66 CHEMBL1020960 (1)
0 / 0
B2RXH2 Lysine-specific demethylase 4E Enzyme CHEMBL66 CHEMBL337309 CHEMBL1613914 (4)
0 / 0
P46063 ATP-dependent DNA helicase Q1 Enzyme CHEMBL66 CHEMBL337309 CHEMBL1492383 CHEMBL1613829 (4)
0 / 0
Q96KQ7 Histone-lysine N-methyltransferase EHMT2 Enzyme CHEMBL66 CHEMBL337309 CHEMBL1738442 (2)
0 / 0
O00255 Menin Unclassified protein CHEMBL337309 CHEMBL1492383 CHEMBL1614257 (1) CHEMBL1614531 (2)
2 / 5
Q03164 Histone-lysine N-methyltransferase 2A Enzyme CHEMBL337309 CHEMBL1492383 CHEMBL1614257 (1) CHEMBL1614531 (2)
1 / 3
Q13951 Core-binding factor subunit beta Unclassified protein CHEMBL66 CHEMBL1613933 (1)
0 / 1
Q01196 Runt-related transcription factor 1 Unclassified protein CHEMBL66 CHEMBL1613933 (1)
1 / 6
Q05513 Protein kinase C zeta type Iota CHEMBL66 CHEMBL769344 (1)
0 / 0
Q04759 Protein kinase C theta type Delta CHEMBL66 CHEMBL769344 (1) CHEMBL768505 (1)
0 / 1
Q02156 Protein kinase C epsilon type Eta CHEMBL66 CHEMBL769344 (1) CHEMBL768505 (1)
0 / 0
O94806 Serine/threonine-protein kinase D3 Pkd CHEMBL66 CHEMBL769344 (1) CHEMBL768505 (1)
0 / 0
P17252 Protein kinase C alpha type Alpha CHEMBL66 CHEMBL769344 (1) CHEMBL768505 (1)
0 / 0
Q05655 Protein kinase C delta type Delta CHEMBL66 CHEMBL769344 (1) CHEMBL768505 (1)
0 / 0
P05129 Protein kinase C gamma type Alpha CHEMBL66 CHEMBL769344 (1) CHEMBL768505 (1)
1 / 1
P05771 Protein kinase C beta type Alpha CHEMBL66 CHEMBL769344 (1) CHEMBL768505 (1)
0 / 0
P24723 Protein kinase C eta type Eta CHEMBL66 CHEMBL769344 (1) CHEMBL768505 (1)
1 / 0
P41743 Protein kinase C iota type Iota CHEMBL66 CHEMBL769344 (1)
0 / 0
Q15139 Serine/threonine-protein kinase D1 Pkd CHEMBL66 CHEMBL769344 (1) CHEMBL768505 (1)
0 / 0

CTD interaction (36)

compound gene gene name gene description interaction interaction type form reference
pmid
C003377 4363 ABCC1
ABC29
ABCC
GS-X
MRP
MRP1
ATP-binding cassette, sub-family C (CFTR/MRP), member 1 taxifolin inhibits the reaction [ABCC1 protein affects the export of S-(2,4-dinitrophenyl)glutathione] affects export
/ decreases reaction
protein 15041478
C003377 4363 ABCC1
ABC29
ABCC
GS-X
MRP
MRP1
ATP-binding cassette, sub-family C (CFTR/MRP), member 1 taxifolin results in decreased activity of ABCC1 protein decreases activity
protein 15041478
C003377 335 APOA1
apolipoprotein A-I taxifolin results in increased expression of APOA1 protein increases expression
protein 11108730
C003377 338 APOB
FLDB
LDLCQ4
apolipoprotein B taxifolin results in decreased expression of APOB protein decreases expression
protein 11108730
C003377 338 APOB
FLDB
LDLCQ4
apolipoprotein B taxifolin results in decreased secretion of APOB protein decreases secretion
protein 15380446
C003377 8900 CCNA1
cyclin A1 taxifolin results in decreased expression of CCNA1 mRNA decreases expression
mRNA 17541156
C003377 993 CDC25A
CDC25A2
cell division cycle 25A (EC:3.1.3.48) taxifolin results in decreased expression of CDC25A mRNA decreases expression
mRNA 17541156
C003377 1571 CYP2E1
CPE1
CYP2E
P450-J
P450C2E
cytochrome P450, family 2, subfamily E, polypeptide 1 (EC:1.14.13.n7) taxifolin results in decreased expression of CYP2E1 mRNA decreases expression
mRNA 17541156
C003377 1630 DCC
CRC18
CRCR1
IGDCC1
MRMV1
deleted in colorectal carcinoma taxifolin results in increased expression of DCC mRNA increases expression
mRNA 17541156
C003377 1950 EGF
HOMG4
URG
epidermal growth factor taxifolin results in decreased expression of EGF mRNA decreases expression
mRNA 17541156
C003377 8817 FGF18
FGF-18
ZFGF5
fibroblast growth factor 18 taxifolin results in decreased expression of FGF18 mRNA decreases expression
mRNA 17541156
C003377 2248 FGF3
HBGF-3
INT2
fibroblast growth factor 3 taxifolin results in decreased expression of FGF3 mRNA decreases expression
mRNA 17541156
C003377 2621 GAS6
AXLLG
AXSF
growth arrest-specific 6 taxifolin results in increased expression of GAS6 mRNA increases expression
mRNA 17541156
C003377 9518 GDF15
GDF-15
MIC-1
MIC1
NAG-1
PDF
PLAB
PTGFB
growth differentiation factor 15 taxifolin results in increased expression of GDF15 mRNA increases expression
mRNA 17541156
C003377 2944 GSTM1
GST1
GSTM1-1
GSTM1a-1a
GSTM1b-1b
GTH4
GTM1
H-B
MU
MU-1
glutathione S-transferase mu 1 (EC:2.5.1.18) taxifolin results in increased expression of GSTM1 mRNA increases expression
mRNA 17541156
C003377 3162 HMOX1
HMOX1D
HO-1
HSP32
bK286B10
heme oxygenase (decycling) 1 (EC:1.14.99.3) taxifolin results in increased expression of HMOX1 protein increases expression
protein 16799064
C003377 3383 ICAM1
BB2
CD54
P3.58
intercellular adhesion molecule 1 taxifolin inhibits the reaction [IFNG protein results in increased expression of ICAM1 mRNA] decreases reaction
/ increases expression
mRNA 12044887
19103272
C003377 3383 ICAM1
BB2
CD54
P3.58
intercellular adhesion molecule 1 taxifolin inhibits the reaction [IFNG protein results in increased expression of ICAM1 protein] decreases reaction
/ increases expression
protein 12044887
19103272
C003377 3458 IFNG
IFG
IFI
interferon, gamma taxifolin inhibits the reaction [IFNG protein results in increased activity of and results in increased localization of STAT1 protein] decreases reaction
/ increases activity
/ increases localization
protein 12044887
C003377 3458 IFNG
IFG
IFI
interferon, gamma taxifolin inhibits the reaction [IFNG protein results in increased expression of ICAM1 mRNA] decreases reaction
/ increases expression
protein 12044887
19103272
C003377 3458 IFNG
IFG
IFI
interferon, gamma taxifolin inhibits the reaction [IFNG protein results in increased expression of ICAM1 protein] decreases reaction
/ increases expression
protein 12044887
19103272
C003377 3458 IFNG
IFG
IFI
interferon, gamma taxifolin inhibits the reaction [IFNG protein results in increased phosphorylation of MAPK8 protein] decreases reaction
/ increases phosphorylation
protein 12044887
C003377 3725 JUN
AP-1
AP1
c-Jun
jun proto-oncogene taxifolin results in decreased expression of JUN mRNA decreases expression
mRNA 17541156
C003377 5599 MAPK8
JNK
JNK-46
JNK1
JNK1A2
JNK21B1/2
PRKM8
SAPK1
SAPK1c
mitogen-activated protein kinase 8 (EC:2.7.11.24) taxifolin inhibits the reaction [IFNG protein results in increased phosphorylation of MAPK8 protein] decreases reaction
/ increases phosphorylation
protein 12044887
C003377 4547 MTTP
ABL
MTP
microsomal triglyceride transfer protein taxifolin results in decreased activity of MTTP protein decreases activity
protein 15380446
C003377 4780 NFE2L2
NRF2
nuclear factor, erythroid 2-like 2 taxifolin results in increased expression of NFE2L2 protein increases expression
protein 16799064
C003377 1728 NQO1
DHQU
DIA4
DTD
NMOR1
NMORI
QR1
NAD(P)H dehydrogenase, quinone 1 (EC:1.6.5.2) taxifolin results in increased activity of NQO1 protein increases activity
protein 17541156
C003377 1728 NQO1
DHQU
DIA4
DTD
NMOR1
NMORI
QR1
NAD(P)H dehydrogenase, quinone 1 (EC:1.6.5.2) taxifolin results in increased expression of NQO1 mRNA increases expression
mRNA 17541156
C003377 5155 PDGFB
IBGC5
PDGF-2
PDGF2
SIS
SSV
c-sis
platelet-derived growth factor beta polypeptide taxifolin results in decreased expression of PDGFB mRNA decreases expression
mRNA 17541156
C003377 5921 RASA1
CM-AVM
CMAVM
GAP
PKWS
RASA
RASGAP
p120GAP
p120RASGAP
RAS p21 protein activator (GTPase activating protein) 1 taxifolin results in decreased expression of RASA1 mRNA decreases expression
mRNA 17541156
C003377 6772 STAT1
CANDF7
ISGF-3
STAT91
signal transducer and activator of transcription 1, 91kDa taxifolin inhibits the reaction [IFNG protein results in increased activity of and results in increased localization of STAT1 protein] decreases reaction
/ increases activity
/ increases localization
protein 12044887
C003377 7187 TRAF3
CAP-1
CAP1
CD40bp
CRAF1
IIAE5
LAP1
TNF receptor-associated factor 3 taxifolin results in increased expression of TRAF3 mRNA increases expression
mRNA 17541156
C003377 7296 TXNRD1
GRIM-12
TR
TR1
TRXR1
TXNR
thioredoxin reductase 1 (EC:1.8.1.9) taxifolin results in increased expression of TXNRD1 mRNA increases expression
mRNA 17541156
C003377 7498 XDH
XO
XOR
xanthine dehydrogenase (EC:1.17.1.4 1.17.3.2) taxifolin inhibits the reaction [XDH protein results in increased chemical synthesis of Superoxides] decreases reaction
/ increases chemical synthesis
protein 19555678
C003377 7507 XPA
XP1
XPAC
xeroderma pigmentosum, complementation group A taxifolin results in increased expression of XPA mRNA increases expression
mRNA 17541156
C003377 7518 XRCC4
X-ray repair complementing defective repair in Chinese hamster cells 4 taxifolin results in increased expression of XRCC4 mRNA increases expression
mRNA 17541156

Related Disease

Diseases related to proteins in ChEMBL interactions

OMIM (41)

OMIM preferred title UniProt
#300438 17-beta-hydroxysteroid dehydrogenase x deficiency Q99714
#210900 Bloom syndrome; blm P54132
#118300 Charcot-marie-tooth disease and deafness Q01453
#118220 Charcot-marie-tooth disease, demyelinating, type 1a; cmt1a Q01453
#114500 Colorectal cancer; crc P18054
#614466 Coronary heart disease, susceptibility to, 6; chds6 P08254
#119900 Digital clubbing, isolated congenital P15428
#609535 Drug metabolism, poor, cyp2c19-related P33261
#608902 Drug metabolism, poor, cyp2d6-related P10635
#237500 Dubin-johnson syndrome; djs Q92887
#133239 Esophageal cancer P18054
#600274 Frontotemporal dementia; ftd P10636
#232300 Glycogen storage disease ii P10253
#139393 Guillain-barre syndrome, familial; gbs Q01453
#605130 Hairy elbows, short stature, facial dysmorphism, and developmental delay Q03164
#145000 Hyperparathyroidism 1; hrpt1 O00255
#145900 Hypertrophic neuropathy of dejerine-sottas Q01453
#259100 Hypertrophic osteoarthropathy, primary, autosomal recessive, 1; phoar1 P15428
#603932 Intervertebral disc disease; idd P14780
#601626 Leukemia, acute myeloid; aml P36888
#300705 Mental retardation, x-linked 17; mrx17 Q99714
#300220 Mental retardation, x-linked, syndromic 10; mrxs10 Q99714
#613073 Metaphyseal anadysplasia 2; mandp2 P14780
#259600 Multicentric osteolysis, nodulosis, and arthropathy; mona P08253
#131100 Multiple endocrine neoplasia, type i; men1 O00255
#162500 Neuropathy, hereditary, with liability to pressure palsies; hnpp Q01453
#260540 Parkinson-dementia syndrome P10636
#172700 Pick disease of brain P10636
#601399 Platelet disorder, familial, with associated myeloid malignancy Q01196
#604906 Schizophrenia 9; sczd9 P49798
#181500 Schizophrenia; sczd P49798
#253300 Spinal muscular atrophy, type i; sma1 Q16637
#253550 Spinal muscular atrophy, type ii; sma2 Q16637
#253400 Spinal muscular atrophy, type iii; sma3 Q16637
#271150 Spinal muscular atrophy, type iv; sma4 Q16637
#605361 Spinocerebellar ataxia 14; sca14 P05129
#602111 Spondyloepimetaphyseal dysplasia, missouri type P45452
#601367 Stroke, ischemic P24723
#601104 Supranuclear palsy, progressive, 1; psnp1 P10636
#278300 Xanthinuria, type i P47989
#278750 Xeroderma pigmentosum, variant type; xpv Q9Y253

KEGG DISEASE (37)

KEGG disease name UniProt
H00033 Adrenal carcinoma O00255 (related)
H00034 Carcinoid O00255 (related)
H00045 Malignant islet cell carcinoma O00255 (related)
H00246 Primary hyperparathyroidism O00255 (related)
H01102 Pituitary adenomas O00255 (related)
H00028 Choriocarcinoma P03956 (related)
P08253 (related)
H00063 Spinocerebellar ataxia (SCA) P05129 (related)
H00025 Penile cancer P08253 (related)
P14780 (related)
H00472 Torg-Winchester syndrome P08253 (related)
H00036 Osteosarcoma P08684 (marker)
H00069 Glycogen storage diseases (GSD) P10253 (related)
H00058 Amyotrophic lateral sclerosis (ALS) P10636 (related)
H00077 Progressive supranuclear palsy (PSP) P10636 (related)
H00078 Frontotemporal lobar degeneration (FTLD) P10636 (related)
H01205 Coumarin resistance P11712 (related)
H00479 Metaphyseal dysplasias P14780 (related)
P45452 (related)
H00457 Primary hypertrophic osteoarthropathy (PHO) P15428 (related)
H01246 Isolated congenital nail clubbing (ICNC) P15428 (related)
H00005 Chronic lymphocytic leukemia (CLL) P28907 (marker)
H01171 Poor drug metabolism (PM) P33261 (related)
H00003 Acute myeloid leukemia (AML) P36888 (related)
Q01196 (related)
Q01196 (marker)
Q13951 (marker)
H00192 Xanthinuria P47989 (related)
H00094 DNA repair defects P54132 (related)
H00296 Defects in RecQ helicases P54132 (related)
H00001 Acute lymphoblastic leukemia (ALL) (precursor B lymphoblastic leukemia) Q01196 (related)
Q01196 (marker)
Q03164 (related)
Q03164 (marker)
H00004 Chronic myeloid leukemia (CML) Q01196 (related)
H00978 Thrombocytopenia (THC) Q01196 (related)
H00264 Charcot-Marie-Tooth disease (CMT) Q01453 (related)
H01296 Hereditary neuropathy with liability to pressure palsies (HNPP) Q01453 (related)
H00002 Acute lymphoblastic leukemia (ALL) (precursor T lymphoblastic leukemia) Q03164 (related)
H00408 Type I diabetes mellitus Q04759 (related)
H00455 Spinal muscular atrophy (SMA) Q16637 (related)
Q16637 (related)
H00208 Hyperbilirubinemia Q92887 (related)
H00480 Non-syndromic X-linked mental retardation Q99714 (related)
H00658 Syndromic X-linked mental retardation Q99714 (related)
H00925 2-Methyl-3-hydroxybutyryl-CoA dehydrogenase (MHBD) deficiency Q99714 (related)
H00403 Disorders of nucleotide excision repair Q9Y253 (related)

Diseases related to CTD interactions

1 disease from interactions of metabolites

MeSH disease OMIM compound disease name evidence type reference
pmid
D006461 C003377 Hemolysis therapeutic
19555678