PCIDB

KNApSAcK Metabolite C00000846

Metabolite

KNApSAcK Entry

id C00000846
Name Geranyl diphosphate / Geranyl pyrophosphate
CAS RN 763-10-0
Standard InChI InChI=1S/C10H20O7P2/c1-9(2)5-4-6-10(3)7-8-16-19(14,15)17-18(11,12)13/h5,7H,4,6,8H2,1-3H3,(H,14,15)(H2,11,12,13)/b10-7+
Standard InChI (Main Layer) InChI=1S/C10H20O7P2/c1-9(2)5-4-6-10(3)7-8-16-19(14,15)17-18(11,12)13/h5,7H,4,6,8H2,1-3H3,(H,14,15)(H2,11,12,13)

Cluster

Phytochemical cluster No. 34
KCF-S cluster No. 3475

Link

ChEMBL

By standard InChI CHEMBL41342
By standard InChI Main Layer CHEMBL41342

KEGG

By LinkDB C00341

CTD

By CAS RN C015234

Human Protein / Gene in interaction

1 ChEMBL Protein in interactions

accession description class description compound assay ID (# of activities) # of diseases
(OMIM / KEGG)
P14324 Farnesyl pyrophosphate synthase Transferase CHEMBL41342 CHEMBL858749 (1) CHEMBL679577 (1)
0 / 0

CTD interaction (2)

compound gene gene name gene description interaction interaction type form reference
pmid
C015234 3156 HMGCR
LDLCQ3
3-hydroxy-3-methylglutaryl-CoA reductase (EC:1.1.1.34) [geranylgeraniol co-treated with geranyl pyrophosphate] results in decreased expression of HMGCR protein affects cotreatment
/ decreases expression
protein 19819230
C015234 5906 RAP1A
KREV-1
KREV1
RAP1
SMGP21
RAP1A, member of RAS oncogene family [geranylgeraniol co-treated with geranyl pyrophosphate] results in decreased expression of RAP1A protein modified form affects cotreatment
/ decreases expression
protein 19819230