KCF-S cluster No. 1681 (6 metabolites)

Corresponding Phytochemical cluster No. 11


Plant Species


Cumulative plant class count

class name count
Liliopsida 13

Cumulative family count

class name count
Melanthiaceae 13

KEGG BRITE br08003 External link 512


Categories (1)

br08003 Category # of metabolite
Steroid alkaloids 1

metabolites link (1)

br08003 Category KEGG ID KNApSAcK ID
Steroid alkaloids C10829 C00002270

Metabolite list (6)

KNApSAcK ID name ChEMBL link CTD link # of proteins in
ChEMBL interaction
/ related OMIM
/ related KEGG DISEASE
# of genes in
CTD interaction
/ related diseases
figure
C00002270 External link 512 Veratramine
CHEMBL464724
CHEMBL1398335
C009649
7 / 2 / 3
C00027719 External link 512 20-Isoveratramine
CHEMBL464724
CHEMBL1398335
7 / 2 / 3
C00027722 External link 512 23-O-beta-D-Glucopyranosyl-20-isoveratramine
C00029200 External link 512 Verarine
C00029201 External link 512 Veratramine N-oxide
C00029203 External link 512 Veratrosine

Human Protein / Gene in interactions

7 ChEMBL Protein in interactions

accession description class description KNApSAcK metabolite in interactions # of diseases
(OMIM / KEGG)
P10635 Cytochrome P450 2D6 Cytochrome P450 2D6 C00002270 C00027719 1 / 0
P11712 Cytochrome P450 2C9 Cytochrome P450 2C9 C00002270 C00027719 0 / 1
P06276 Cholinesterase Hydrolase C00002270 C00027719 0 / 0
P05177 Cytochrome P450 1A2 Cytochrome P450 1A2 C00002270 C00027719 0 / 0
P16050 Arachidonate 15-lipoxygenase Enzyme C00002270 C00027719 0 / 0
P33261 Cytochrome P450 2C19 Cytochrome P450 2C19 C00002270 C00027719 1 / 1
P08684 Cytochrome P450 3A4 Cytochrome P450 3A4 C00002270 C00027719 0 / 1

Related Diseases

Diseases related to proteins in ChEMBL interactions

OMIM (2)

OMIM preferred title UniProt
#609535 Drug metabolism, poor, cyp2c19-related P33261
#608902 Drug metabolism, poor, cyp2d6-related P10635

KEGG DISEASE (3)

KEGG name UniProt
H00036 Osteosarcoma P08684 (marker)
H01205 Coumarin resistance P11712 (related)
H01171 Poor drug metabolism (PM) P33261 (related)