PCIDB

KCF-S cluster No. 251 (26 metabolites)

Plant Species

Cumulative plant class count

class name count
Liliopsida 5

Cumulative family count

class name count
Streptomycetaceae 42
Amaryllidaceae 5
Micromonosporaceae 4
Thermomonosporaceae 2
Polycitoridae 2
Lamellariidae 2
Nocardiaceae 1

KEGG BRITE br08003 External link 512

Categories (0)

br08003 Category # of metabolite

metabolites link (0)

br08003 Category KEGG ID KNApSAcK ID

Metabolite list (26)

KNApSAcK ID name ChEMBL link CTD link # of proteins in
ChEMBL interaction
/ related OMIM
/ related KEGG DISEASE 		# of genes in
CTD interaction
/ related diseases 		figure
C00015228 External link 512 Indocarbazostatin
/ (+)-Indocarbazostatin
C00015229 External link 512 Indocarbazostatin B
/ (-)-Indocarbazostatin B
C00015660 External link 512 4'-N-Methyl-5'-hydroxystaurosporine
C00015661 External link 512 5'-Hydroxystaurosporine
C00016476 External link 512 CGP 58546
/ O3'-Demethylstaurosporine
/ 3'-Demethoxy-3'-hydroxystaurosporine
CHEMBL600527
C00016751 External link 512 RK 1409B
/ 3'-epi-RK-286C
CHEMBL423731
C077632
14 / 2 / 2
C00016938 External link 512 MLR 52
C087121
C00017237 External link 512 RK 1409
/ BMY 41950
/ 7-Oxostaurosporine
CHEMBL337026
16 / 3 / 10
C00017543 External link 512 TAN 999
C00017544 External link 512 TAN 1030A
C061876
C00017573 External link 512 RK 286C
/ (+)-RK 286C
/ Antibiotic RK 286C
/ (+)-Antibiotic RK 286C
CHEMBL423731
C063438
14 / 2 / 2
C00017671 External link 512 UCN 02
/ 7-epi-Hydroxystaurosporine
CHEMBL339799
CHEMBL338049
CHEMBL574737
CHEMBL601799
CHEMBL1236539
81 / 19 / 20
C00017726 External link 512 SF 2370
/ (+)-Antibiotic K 252a
/ (+)-Antibiotic SF 2370
/ Protein kinase inhibitor K252a
CHEMBL281948
CHEMBL416056
CHEMBL94678
CHEMBL1490533
CHEMBL1591330
C047321
258 / 119 / 82
C00017792 External link 512 K252d
/ Antibiotic K 252d
C00018127 External link 512 AM-2282
/ CGP 39360
/ Staurosporin
/ Staurosporine
/ Antibiotic 230
/ (+)-Staurosporine
/ Antibiotic AM 2282
CHEMBL290084
CHEMBL162
CHEMBL364347
CHEMBL388978
CHEMBL1537489
CHEMBL1709437
CHEMBL1979949
CHEMBL1980995
D019311
451 / 200 / 129 66 / 1
C00024753 External link 512 UCN-01
/ (+)-UCN-01
/ 7-Hydroxystaurosporine
CHEMBL339799
CHEMBL338049
CHEMBL574737
CHEMBL601799
CHEMBL1236539
C054852
81 / 19 / 20 29 / 1
C00026595 External link 512 Indocarbazostatin C
/ (+)-Indocarbazostatin C
C00026596 External link 512 Indocarbazostatin D
C00027661 External link 512 11-Hydroxyvittatine
C00027732 External link 512 3,11-Dihydroxy-staurosporine
C00027760 External link 512 4'-N-demethyl-11-hydroxy-staurosporine
C00027763 External link 512 5'-Hydroxy-staurosporine
C00028349 External link 512 Holyrine A
C00028350 External link 512 Holyrine B
C00028707 External link 512 N-Methylstaurosporine
C065079
C00029261 External link 512 ZHD-0501

Human Protein / Gene in interactions

452 ChEMBL Protein in interactions

accession description class description KNApSAcK metabolite in interactions # of diseases
(OMIM / KEGG)
P22612 cAMP-dependent protein kinase catalytic subunit gamma Pka C00016751 C00017237 C00017573 C00017671 C00017726 C00018127 C00024753 0 / 0
Q05513 Protein kinase C zeta type Iota C00016751 C00017237 C00017573 C00017671 C00017726 C00018127 C00024753 0 / 0
Q02156 Protein kinase C epsilon type Eta C00016751 C00017237 C00017573 C00017671 C00017726 C00018127 C00024753 0 / 0
P41743 Protein kinase C iota type Iota C00016751 C00017237 C00017573 C00017671 C00017726 C00018127 C00024753 0 / 0
O94806 Serine/threonine-protein kinase D3 Pkd C00016751 C00017237 C00017573 C00017671 C00017726 C00018127 C00024753 0 / 0
P22694 cAMP-dependent protein kinase catalytic subunit beta Pka C00016751 C00017237 C00017573 C00017671 C00017726 C00018127 C00024753 0 / 0
Q15139 Serine/threonine-protein kinase D1 Pkd C00016751 C00017237 C00017573 C00017671 C00017726 C00018127 C00024753 0 / 0
Q04759 Protein kinase C theta type Delta C00016751 C00017237 C00017573 C00017671 C00017726 C00018127 C00024753 0 / 1
P24723 Protein kinase C eta type Eta C00016751 C00017237 C00017573 C00017671 C00017726 C00018127 C00024753 1 / 0
P17252 Protein kinase C alpha type Alpha C00016751 C00017237 C00017573 C00017671 C00017726 C00018127 C00024753 0 / 0
P17612 cAMP-dependent protein kinase catalytic subunit alpha Pka C00016751 C00017237 C00017573 C00017671 C00017726 C00018127 C00024753 0 / 0
P05771 Protein kinase C beta type Alpha C00016751 C00017237 C00017573 C00017671 C00017726 C00018127 C00024753 0 / 0
P05129 Protein kinase C gamma type Alpha C00016751 C00017237 C00017573 C00017671 C00017726 C00018127 C00024753 1 / 1
Q05655 Protein kinase C delta type Delta C00016751 C00017237 C00017573 C00017671 C00017726 C00018127 C00024753 0 / 0
P12931 Proto-oncogene tyrosine-protein kinase Src Src C00017237 C00017671 C00017726 C00018127 C00024753 0 / 0
P00533 Epidermal growth factor receptor TK tyrosine-protein kinase EGFR subfamily C00017237 C00017671 C00017726 C00018127 C00024753 1 / 8
Q13188 Serine/threonine-protein kinase 3 STE serine/threonine protein kinase MST subfamily C00017671 C00017726 C00018127 C00024753 0 / 0
Q9H2X6 Homeodomain-interacting protein kinase 2 CMGC dual-specificity kinase HIPK C00017671 C00017726 C00018127 C00024753 0 / 0
Q9HC98 Serine/threonine-protein kinase Nek6 Nek C00017671 C00017726 C00018127 C00024753 0 / 0
P51812 Ribosomal protein S6 kinase alpha-3 Rskb C00017671 C00017726 C00018127 C00024753 2 / 2
O00141 Serine/threonine-protein kinase Sgk1 AGC serine/threonine protein kinase SGK subfamily C00017671 C00017726 C00018127 C00024753 0 / 0
P31749 RAC-alpha serine/threonine-protein kinase Akt C00017671 C00017726 C00018127 C00024753 4 / 1
Q14012 Calcium/calmodulin-dependent protein kinase type 1 Camk1 C00017671 C00017726 C00018127 C00024753 0 / 0
O75116 Rho-associated protein kinase 2 Rock C00017671 C00017726 C00018127 C00024753 0 / 0
Q8IW41 MAP kinase-activated protein kinase 5 CAMK serine/threonine protein kinase MAPKAPK C00017671 C00017726 C00018127 C00024753 0 / 0
P53350 Serine/threonine-protein kinase PLK1 PLK serine/threonine protein kinase subfamily C00017671 C00017726 C00018127 C00024753 0 / 0
P45983 Mitogen-activated protein kinase 8 Jnk C00017671 C00017726 C00018127 C00024753 0 / 0
P28482 Mitogen-activated protein kinase 1 Erk C00017671 C00017726 C00018127 C00024753 0 / 0
P49137 MAP kinase-activated protein kinase 2 CAMK serine/threonine protein kinase MAPKAPK C00017671 C00017726 C00018127 C00024753 0 / 0
Q8TDX7 Serine/threonine-protein kinase Nek7 Nek C00017671 C00017726 C00018127 C00024753 0 / 0
Q96GD4 Aurora kinase B Aur C00017671 C00017726 C00018127 C00024753 0 / 0
Q9P1W9 Serine/threonine-protein kinase pim-2 Pim C00017671 C00017726 C00018127 C00024753 0 / 0
P48730 Casein kinase I isoform delta Ck1 C00017671 C00017726 C00018127 C00024753 1 / 0
Q15759 Mitogen-activated protein kinase 11 p38 C00017671 C00017726 C00018127 C00024753 0 / 0
Q16539 Mitogen-activated protein kinase 14 p38 C00017671 C00017726 C00018127 C00024753 0 / 0
P68400 Casein kinase II subunit alpha Ck2 C00017671 C00017726 C00018127 C00024753 0 / 0
Q96RR4 Calcium/calmodulin-dependent protein kinase kinase 2 META serine/threonine protein kinase subfamily C00017671 C00017726 C00018127 C00024753 0 / 0
P51955 Serine/threonine-protein kinase Nek2 Nek C00017671 C00017726 C00018127 C00024753 0 / 0
O15530 3-phosphoinositide-dependent protein kinase 1 Pdk1 C00017671 C00017726 C00018127 C00024753 0 / 0
P53779 Mitogen-activated protein kinase 10 Jnk C00017671 C00017726 C00018127 C00024753 0 / 1
P41240 Tyrosine-protein kinase CSK Csk C00017671 C00017726 C00018127 C00024753 0 / 0
O15264 Mitogen-activated protein kinase 13 p38 C00017671 C00017726 C00018127 C00024753 0 / 0
Q15418 Ribosomal protein S6 kinase alpha-1 Rskb C00017671 C00017726 C00018127 C00024753 0 / 0
P49841 Glycogen synthase kinase-3 beta Gsk C00017671 C00017726 C00018127 C00024753 0 / 0
P45984 Mitogen-activated protein kinase 9 Jnk C00017671 C00017726 C00018127 C00024753 0 / 0
P67870 Casein kinase II subunit beta REG serine/threonine protein kinase family C00017671 C00017726 C00018127 C00024753 0 / 0
O96013 Serine/threonine-protein kinase PAK 4 STE serine/threonine protein kinase PAKB subfamily C00017671 C00017726 C00018127 C00024753 0 / 0
P27361 Mitogen-activated protein kinase 3 Erk C00017671 C00017726 C00018127 C00024753 0 / 0
Q92630 Dual specificity tyrosine-phosphorylation-regulated kinase 2 CMGC dual-specificity kinase DYRK2 C00017671 C00017726 C00018127 C00024753 0 / 0
Q96SB4 SRSF protein kinase 1 Srpk C00017671 C00017726 C00018127 C00024753 0 / 0
P53778 Mitogen-activated protein kinase 12 p38 C00017671 C00017726 C00018127 C00024753 0 / 0
O00418 Eukaryotic elongation factor 2 kinase Atypical serine/threonine protein kinase alpha subfamily C00017671 C00017726 C00018127 C00024753 0 / 0
Q9P286 Serine/threonine-protein kinase PAK 7 STE serine/threonine protein kinase PAKB subfamily C00017671 C00017726 C00018127 C00024753 0 / 0
O14757 Serine/threonine-protein kinase Chk1 Chk1 C00017671 C00017726 C00018127 C00024753 0 / 0
P11309 Serine/threonine-protein kinase pim-1 Pim C00017671 C00017726 C00018127 C00024753 0 / 0
Q02750 Dual specificity mitogen-activated protein kinase kinase 1 Ste7 C00017671 C00017726 C00018127 C00024753 1 / 1
Q16513 Serine/threonine-protein kinase N2 Pkn C00017671 C00017726 C00018127 C00024753 0 / 0
O14920 Inhibitor of nuclear factor kappa-B kinase subunit beta Other serine/threonine protein kinase C00017671 C00017726 C00018127 C00024753 0 / 0
O75582 Ribosomal protein S6 kinase alpha-5 CAMK serine/threonine protein kinase MSKB subfamily C00017671 C00017726 C00018127 C00024753 0 / 0
P31751 RAC-beta serine/threonine-protein kinase Akt C00017671 C00017726 C00018127 C00024753 2 / 2
O96017 Serine/threonine-protein kinase Chk2 Rad53 C00017671 C00017726 C00018127 C00024753 4 / 1
Q15746 Myosin light chain kinase, smooth muscle Mlck C00017671 C00017726 C00018127 C00024753 1 / 1
Q86V86 Serine/threonine-protein kinase pim-3 Pim C00017671 C00017726 C00018127 C00024753 0 / 0
P24941 Cyclin-dependent kinase 2 Cdc2 C00017671 C00017726 C00018127 C00024753 0 / 0
P78396 Cyclin-A1 Other cytosolic protein C00017671 C00017726 C00018127 C00024753 0 / 0
P20248 Cyclin-A2 Other cytosolic protein C00017671 C00017726 C00018127 C00024753 0 / 0
Q14680 Maternal embryonic leucine zipper kinase Melk C00017671 C00017726 C00018127 C00024753 0 / 0
Q9H422 Homeodomain-interacting protein kinase 3 CMGC dual-specificity kinase HIPK C00017671 C00017726 C00018127 C00024753 0 / 0
Q16644 MAP kinase-activated protein kinase 3 CAMK serine/threonine protein kinase MAPKAPK C00017671 C00017726 C00018127 C00024753 0 / 0
Q9NQU5 Serine/threonine-protein kinase PAK 6 STE serine/threonine protein kinase PAKB subfamily C00017671 C00017726 C00018127 C00024753 0 / 0
Q9HBH9 MAP kinase-interacting serine/threonine-protein kinase 2 CAMK serine/threonine protein kinase MNK subfamily C00017671 C00017726 C00018127 C00024753 0 / 0
Q9UQB9 Aurora kinase C Aur C00017671 C00017726 C00018127 C00024753 1 / 1
P23443 Ribosomal protein S6 kinase beta-1 p70 C00017671 C00017726 C00018127 C00024753 0 / 0
P19784 Casein kinase II subunit alpha' Ck2 C00017671 C00017726 C00018127 C00024753 0 / 0
Q8IWQ3 Serine/threonine-protein kinase BRSK2 CAMK serine/threonine protein kinase BRSK subfamily C00017671 C00017726 C00018127 C00024753 0 / 0
P27448 MAP/microtubule affinity-regulating kinase 3 CAMK serine/threonine protein kinase MARK subfamily C00017671 C00018127 C00024753 0 / 0
Q8TD08 Mitogen-activated protein kinase 15 Mapk C00017671 C00018127 C00024753 0 / 0
Q8N5S9 Calcium/calmodulin-dependent protein kinase kinase 1 META serine/threonine protein kinase subfamily C00017671 C00018127 C00024753 0 / 0
Q13627 Dual specificity tyrosine-phosphorylation-regulated kinase 1A CMGC dual-specificity kinase DYRK1 C00017671 C00018127 C00024753 1 / 0
Q9BUB5 MAP kinase-interacting serine/threonine-protein kinase 1 CAMK serine/threonine protein kinase MNK subfamily C00017671 C00018127 C00024753 0 / 0
P08581 Hepatocyte growth factor receptor TK tyrosine-protein kinase MET subfamily C00017726 C00018127 2 / 3
Q9UGI9 5'-AMP-activated protein kinase subunit gamma-3 Kinase C00017726 C00018127 0 / 0
Q01538 Myelin transcription factor 1 Unclassified protein C00017726 C00018127 0 / 0
P62942 Peptidyl-prolyl cis-trans isomerase FKBP1A Isomerase C00017726 C00018127 0 / 0
Q96PF2 Testis-specific serine/threonine-protein kinase 2 CAMK serine/threonine protein kinase TSSK subfamily C00017726 C00018127 0 / 0
P51956 Serine/threonine-protein kinase Nek3 Nek1 C00017726 C00018127 0 / 0
P30281 G1/S-specific cyclin-D3 Other cytosolic protein C00017726 C00018127 0 / 1
O60563 Cyclin-T1 Other cytosolic protein C00017726 C00018127 0 / 0
P00519 Tyrosine-protein kinase ABL1 Abl C00017726 C00018127 1 / 2
P46019 Phosphorylase b kinase regulatory subunit alpha, liver isoform REG serine/threonine protein kinase family C00017726 C00018127 1 / 1
P46020 Phosphorylase b kinase regulatory subunit alpha, skeletal muscle isoform REG serine/threonine protein kinase family C00017726 C00018127 1 / 1
Q93100 Phosphorylase b kinase regulatory subunit beta REG serine/threonine protein kinase family C00017726 C00018127 1 / 1
Q00534 Cyclin-dependent kinase 6 CMGC serine/threonine protein kinase family C00017726 C00018127 1 / 0
Q9UGJ0 5'-AMP-activated protein kinase subunit gamma-2 REG serine/threonine protein kinase family C00017726 C00018127 3 / 3
P21709 Ephrin type-A receptor 1 Eph C00017726 C00018127 0 / 0
O43741 5'-AMP-activated protein kinase subunit beta-2 REG serine/threonine protein kinase family C00017726 C00018127 0 / 0
Q9UK32 Ribosomal protein S6 kinase alpha-6 Rskb C00017726 C00018127 0 / 0
Q04912 Macrophage-stimulating protein receptor TK tyrosine-protein kinase MET subfamily C00017726 C00018127 0 / 0
Q9Y478 5'-AMP-activated protein kinase subunit beta-1 REG serine/threonine protein kinase family C00017726 C00018127 0 / 0
Q13557 Calcium/calmodulin-dependent protein kinase type II subunit delta Camk2 C00017726 C00018127 0 / 0
P54619 5'-AMP-activated protein kinase subunit gamma-1 REG serine/threonine protein kinase family C00017726 C00018127 0 / 0
P42345 Serine/threonine-protein kinase mTOR Enzyme C00017726 C00018127 0 / 0
P06241 Tyrosine-protein kinase Fyn Src C00017726 C00018127 0 / 0
P80192 Mitogen-activated protein kinase kinase kinase 9 TKL dual-specificity kinase MLK C00017726 C00018127 0 / 0
P06493 Cyclin-dependent kinase 1 Cdc2 C00017726 C00018127 0 / 0
P43403 Tyrosine-protein kinase ZAP-70 Syk C00017726 C00018127 1 / 2
P16234 Platelet-derived growth factor receptor alpha Pdgfr C00017726 C00018127 2 / 1
P36897 TGF-beta receptor type-1 TKL dual-specificity kinase STKR type 1 subfamily C00017726 C00018127 3 / 2
Q8WWL7 G2/mitotic-specific cyclin-B3 Other cytosolic protein C00017726 C00018127 0 / 0
Q00535 Cyclin-dependent kinase 5 Cdk5 C00017726 C00018127 0 / 0
O95067 G2/mitotic-specific cyclin-B2 Other cytosolic protein C00017726 C00018127 0 / 0
O96020 G1/S-specific cyclin-E2 Other cytosolic protein C00017726 C00018127 0 / 2
P49761 Dual specificity protein kinase CLK3 Clk C00017726 C00018127 0 / 0
P51813 Cytoplasmic tyrosine-protein kinase BMX Tec C00017726 C00018127 0 / 0
P51946 Cyclin-H Other cytosolic protein C00017726 C00018127 0 / 0
Q9UL54 Serine/threonine-protein kinase TAO2 STE serine/threonine protein kinase TAO subfamily C00017726 C00018127 0 / 0
P51817 cAMP-dependent protein kinase catalytic subunit PRKX Pka C00017726 C00018127 0 / 0
P19525 Interferon-induced, double-stranded RNA-activated protein kinase Pkr C00017726 C00018127 0 / 0
Q06187 Tyrosine-protein kinase BTK Tec C00017726 C00018127 2 / 2
Q8TDC3 Serine/threonine-protein kinase BRSK1 CAMK serine/threonine protein kinase BRSK subfamily C00017726 C00018127 0 / 0
Q8N568 Serine/threonine-protein kinase DCLK2 CAMK serine/threonine protein kinase DCAMK1 C00017726 C00018127 0 / 0
Q9Y6M4 Casein kinase I isoform gamma-3 Ck1-g C00017726 C00018127 0 / 0
Q9Y6E0 Serine/threonine-protein kinase 24 STE serine/threonine protein kinase YSK subfamily C00017726 C00018127 0 / 0
Q9UBE8 Serine/threonine-protein kinase NLK CMGC serine/threonine protein kinase NMO subfamily C00017726 C00018127 0 / 0
Q12866 Tyrosine-protein kinase Mer TK tyrosine-protein kinase AXL C00017726 C00018127 1 / 1
Q9UPE1 SRSF protein kinase 3 Srpk C00017726 C00018127 0 / 0
P14635 G2/mitotic-specific cyclin-B1 Other cytosolic protein C00017726 C00018127 0 / 0
Q15078 Cyclin-dependent kinase 5 activator 1 REG serine/threonine protein kinase family C00017726 C00018127 0 / 0
P11802 Cyclin-dependent kinase 4 CMGC serine/threonine protein kinase family C00017726 C00018127 1 / 3
P24385 G1/S-specific cyclin-D1 Other cytosolic protein C00017726 C00018127 1 / 8
P24864 G1/S-specific cyclin-E1 Other cytosolic protein C00017726 C00018127 0 / 2
Q13555 Calcium/calmodulin-dependent protein kinase type II subunit gamma Camk2 C00017726 C00018127 0 / 0
Q9BZL6 Serine/threonine-protein kinase D2 Pkd C00017726 C00018127 0 / 0
Q9Y5S2 Serine/threonine-protein kinase MRCK beta AGC serine/threonine protein kinase GEK subfamily C00017726 C00018127 0 / 0
P30530 Tyrosine-protein kinase receptor UFO TK tyrosine-protein kinase AXL subfamily C00017726 C00018127 0 / 0
Q8N4C8 Misshapen-like kinase 1 STE serine/threonine protein kinase MSN subfamily C00017726 C00018127 0 / 0
Q07912 Activated CDC42 kinase 1 TK tyrosine-protein kinase ACK subfamily C00017726 C00018127 0 / 0
P54762 Ephrin type-B receptor 1 Eph C00017726 C00018127 0 / 0
P54756 Ephrin type-A receptor 5 Eph C00017726 C00018127 0 / 0
P49760 Dual specificity protein kinase CLK2 Clk C00017726 C00018127 0 / 0
P35557 Glucokinase Enzyme C00017726 C00018127 3 / 3
P29322 Ephrin type-A receptor 8 Eph C00017726 C00018127 0 / 0
P42685 Tyrosine-protein kinase FRK Src C00017726 C00018127 0 / 0
O14733 Dual specificity mitogen-activated protein kinase kinase 7 Ste7 C00017726 C00018127 0 / 0
Q13043 Serine/threonine-protein kinase 4 STE serine/threonine protein kinase MST subfamily C00017726 C00018127 1 / 0
Q9NYY3 Serine/threonine-protein kinase PLK2 Plk2 C00017726 C00018127 0 / 0
P51451 Tyrosine-protein kinase Blk Src C00017726 C00018127 1 / 1
P43250 G protein-coupled receptor kinase 6 AGC serine/threonine protein kinase GRK subfamily C00017726 C00018127 0 / 0
Q96BR1 Serine/threonine-protein kinase Sgk3 AGC serine/threonine protein kinase SGK subfamily C00017726 C00018127 0 / 0
Q5VT25 Serine/threonine-protein kinase MRCK alpha AGC serine/threonine protein kinase GEK subfamily C00017726 C00018127 0 / 0
P53355 Death-associated protein kinase 1 Dapk C00017726 C00018127 0 / 1
Q9UHD2 Serine/threonine-protein kinase TBK1 Ikk C00017726 C00018127 1 / 0
O43293 Death-associated protein kinase 3 Dapk C00017726 C00018127 0 / 0
Q16566 Calcium/calmodulin-dependent protein kinase type IV Camk1 C00017726 C00018127 0 / 0
P43405 Tyrosine-protein kinase SYK Syk C00017726 C00018127 0 / 0
P04049 RAF proto-oncogene serine/threonine-protein kinase Raf C00017726 C00018127 2 / 0
Q14289 Protein-tyrosine kinase 2-beta Fak C00017726 C00018127 0 / 0
Q9Y243 RAC-gamma serine/threonine-protein kinase Akt C00017726 C00018127 1 / 0
P52333 Tyrosine-protein kinase JAK3 Jakb C00017726 C00018127 1 / 1
P54646 5'-AMP-activated protein kinase catalytic subunit alpha-2 Ampk C00017726 C00018127 0 / 0
P08922 Proto-oncogene tyrosine-protein kinase ROS TK tyrosine-protein kinase SEV C00017726 C00018127 0 / 1
Q13464 Rho-associated protein kinase 1 Rock C00017726 C00018127 0 / 0
Q13882 Protein-tyrosine kinase 6 Src C00017726 C00018127 0 / 0
Q7KZI7 Serine/threonine-protein kinase MARK2 CAMK serine/threonine protein kinase MARK subfamily C00017726 C00018127 0 / 0
Q13554 Calcium/calmodulin-dependent protein kinase type II subunit beta Camk2 C00017726 C00018127 0 / 0
Q9HCP0 Casein kinase I isoform gamma-1 Ck1 C00017726 C00018127 0 / 0
P17948 Vascular endothelial growth factor receptor 1 Vegfr C00017726 C00018127 0 / 0
P06239 Tyrosine-protein kinase Lck Src C00017726 C00018127 0 / 1
P10721 Mast/stem cell growth factor receptor Kit Pdgfr C00017726 C00018127 4 / 3
P10636 Microtubule-associated protein tau Unclassified protein C00017726 C00018127 4 / 3
P78368 Casein kinase I isoform gamma-2 Ck1 C00017726 C00018127 0 / 0
Q86Z02 Homeodomain-interacting protein kinase 1 CMGC serine/threonine protein kinase HIPK subfamily C00017726 C00018127 0 / 0
Q16584 Mitogen-activated protein kinase kinase kinase 11 TKL dual-specificity kinase MLK C00017726 C00018127 0 / 0
Q02779 Mitogen-activated protein kinase kinase kinase 10 TKL dual-specificity kinase MLK C00017726 C00018127 0 / 0
Q86UE8 Serine/threonine-protein kinase tousled-like 2 TLK serine/threonine protein kinase C00017726 C00018127 0 / 0
P36888 Receptor-type tyrosine-protein kinase FLT3 Pdgfr C00017726 C00018127 1 / 1
P36896 Activin receptor type-1B TKL serine/threonine protein kinase STKR type 1 subfamily C00017726 C00018127 0 / 0
P07947 Tyrosine-protein kinase Yes Src C00017726 C00018127 0 / 0
P51617 Interleukin-1 receptor-associated kinase 1 Irak C00017726 C00018127 0 / 0
Q9NWZ3 Interleukin-1 receptor-associated kinase 4 Irak C00017726 C00018127 2 / 1
Q15831 Serine/threonine-protein kinase STK11 Lkb C00017726 C00018127 2 / 2
O43353 Receptor-interacting serine/threonine-protein kinase 2 Ripk C00017726 C00018127 0 / 0
P07949 Proto-oncogene tyrosine-protein kinase receptor Ret Ret C00017726 C00018127 9 / 4
P29320 Ephrin type-A receptor 3 Eph C00017726 C00018127 1 / 0
P54764 Ephrin type-A receptor 4 Eph C00017726 C00018127 0 / 0
Q9UEE5 Serine/threonine-protein kinase 17A Dapk C00017726 C00018127 0 / 0
O14965 Aurora kinase A Aur C00017726 C00018127 0 / 0
Q15303 Receptor tyrosine-protein kinase erbB-4 TK tyrosine-protein kinase EGFR subfamily C00017726 C00018127 0 / 0
Q16620 BDNF/NT-3 growth factors receptor Trk C00017726 C00018127 1 / 1
P42680 Tyrosine-protein kinase Tec Tec C00017726 C00018127 0 / 0
P42681 Tyrosine-protein kinase TXK Tec C00017726 C00018127 0 / 0
Q8IU85 Calcium/calmodulin-dependent protein kinase type 1D Camk1 C00017726 C00018127 0 / 0
P04629 High affinity nerve growth factor receptor Trk C00017726 C00018127 2 / 3
Q15349 Ribosomal protein S6 kinase alpha-2 Rskb C00017726 C00018127 0 / 0
O43781 Dual specificity tyrosine-phosphorylation-regulated kinase 3 CMGC dual-specificity kinase DYRK2 C00017671 C00024753 0 / 0
P07332 Tyrosine-protein kinase Fes/Fps Fer C00017726 C00018127 0 / 0
P16591 Tyrosine-protein kinase Fer Fer C00017726 C00018127 0 / 0
P09769 Tyrosine-protein kinase Fgr Src C00017726 C00018127 0 / 0
P54760 Ephrin type-B receptor 4 Eph C00017726 C00018127 0 / 0
P07333 Macrophage colony-stimulating factor 1 receptor Pdgfr C00017726 C00018127 1 / 1
Q09013 Myotonin-protein kinase AGC serine/threonine protein kinase GEK subfamily C00017726 C00018127 1 / 1
P07948 Tyrosine-protein kinase Lyn Src C00017726 C00018127 0 / 0
P08631 Tyrosine-protein kinase HCK Src C00017726 C00018127 0 / 0
Q16832 Discoidin domain-containing receptor 2 Ddr C00017726 C00018127 1 / 1
Q8IYT8 Serine/threonine-protein kinase ULK2 ULK serine/threonine protein kinase C00017726 C00018127 0 / 0
Q13976 cGMP-dependent protein kinase 1 Pkg C00017726 C00018127 0 / 0
P49840 Glycogen synthase kinase-3 alpha Gsk C00017726 C00018127 0 / 0
Q9BYT3 Serine/threonine-protein kinase 33 Unique CAMK serine/threonine protein kinase C00017726 C00018127 0 / 0
P57059 Serine/threonine-protein kinase SIK1 CAMK serine/threonine protein kinase QIK subfamily C00017726 C00018127 0 / 0
Q08881 Tyrosine-protein kinase ITK/TSK Tec C00017726 C00018127 1 / 1
P78362 SRSF protein kinase 2 Srpk C00017726 C00018127 0 / 0
Q9HBY8 Serine/threonine-protein kinase Sgk2 AGC serine/threonine protein kinase SGK subfamily C00017726 C00018127 0 / 0
P11362 Fibroblast growth factor receptor 1 Fgfr C00017726 C00018127 4 / 5
Q8TF76 Serine/threonine-protein kinase haspin Haspin C00017726 C00018127 0 / 0
Q8WTQ7 G protein-coupled receptor kinase 7 AGC serine/threonine protein kinase GRK subfamily C00017726 C00018127 0 / 0
Q8NG66 Serine/threonine-protein kinase Nek11 Nek11 C00017726 C00018127 0 / 0
Q86Y07 Serine/threonine-protein kinase VRK2 Enzyme C00017726 C00018127 0 / 0
Q9H2K8 Serine/threonine-protein kinase TAO3 STE serine/threonine protein kinase TAO subfamily C00017726 C00018127 0 / 0
Q9Y3S1 Serine/threonine-protein kinase WNK2 WNK serine/threonine protein kinase subfamily C00017726 C00018127 0 / 0
Q9BXA7 Testis-specific serine/threonine-protein kinase 1 Tssk C00017726 C00018127 0 / 0
O43318 Mitogen-activated protein kinase kinase kinase 7 Tak1 C00017726 C00018127 0 / 0
P14616 Insulin receptor-related protein TK tyrosine-protein kinase INSR C00017726 C00018127 0 / 0
Q7L7X3 Serine/threonine-protein kinase TAO1 STE serine/threonine protein kinase TAO subfamily C00017726 C00018127 0 / 0
Q16816 Phosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform Phk C00017726 C00018127 0 / 0
Q6PHR2 Serine/threonine-protein kinase ULK3 ULK serine/threonine protein kinase C00017726 C00018127 0 / 0
P42684 Abelson tyrosine-protein kinase 2 Abl C00017726 C00018127 0 / 0
Q05397 Focal adhesion kinase 1 Fak C00017726 C00018127 0 / 0
Q9UIK4 Death-associated protein kinase 2 Dapk C00017726 C00018127 0 / 0
P29323 Ephrin type-B receptor 2 Eph C00017726 C00018127 2 / 0
O75914 Serine/threonine-protein kinase PAK 3 STE serine/threonine protein kinase PAKA subfamily C00017726 C00018127 1 / 1
Q06418 Tyrosine-protein kinase receptor TYRO3 TK tyrosine-protein kinase AXL C00017726 C00018127 0 / 0
P15735 Phosphorylase b kinase gamma catalytic chain, liver/testis isoform Phk C00017726 C00018127 1 / 1
Q00526 Cyclin-dependent kinase 3 Cdc2 C00017726 C00018127 0 / 0
Q02763 Angiopoietin-1 receptor Tie C00017726 C00018127 1 / 1
Q13177 Serine/threonine-protein kinase PAK 2 STE serine/threonine protein kinase PAKA subfamily C00017726 C00018127 0 / 0
P29317 Ephrin type-A receptor 2 Eph C00017726 C00018127 1 / 1
P53667 LIM domain kinase 1 Limk C00017726 C00018127 0 / 0
Q15375 Ephrin type-A receptor 7 Eph C00017726 C00018127 0 / 0
P21802 Fibroblast growth factor receptor 2 TK tyrosine-protein kinase TLK subfamily C00017726 C00018127 9 / 3
Q99683 Mitogen-activated protein kinase kinase kinase 5 Ste11 C00017726 C00018127 0 / 0
O94804 Serine/threonine-protein kinase 10 STE serine/threonine protein kinase SLK subfamily C00017726 C00018127 1 / 0
P50613 Cyclin-dependent kinase 7 Cdk7 C00017726 C00018127 0 / 0
Q9H4B4 Serine/threonine-protein kinase PLK3 PLK serine/threonine protein kinase subfamily C00017726 C00018127 0 / 0
P54753 Ephrin type-B receptor 3 Eph C00017726 C00018127 0 / 0
Q9UM73 ALK tyrosine kinase receptor TKL serine/threonine protein kinase STKR type 1 subfamily C00017726 C00018127 1 / 1
P22607 Fibroblast growth factor receptor 3 Fgfr C00017726 C00018127 14 / 6
P22455 Fibroblast growth factor receptor 4 Fgfr C00017726 C00018127 0 / 0
P35916 Vascular endothelial growth factor receptor 3 Vegfr C00017726 C00018127 2 / 1
P50750 Cyclin-dependent kinase 9 Cdk9 C00017726 C00018127 0 / 0
Q9P0L2 Serine/threonine-protein kinase MARK1 CAMK serine/threonine protein kinase MARK subfamily C00017726 C00018127 0 / 0
Q13131 5'-AMP-activated protein kinase catalytic subunit alpha-1 Ampk C00017726 C00018127 0 / 0
Q9BYP7 Serine/threonine-protein kinase WNK3 WNK serine/threonine protein kinase subfamily C00017726 C00018127 0 / 0
P35968 Vascular endothelial growth factor receptor 2 Vegfr C00017726 C00018127 1 / 0
O15146 Muscle, skeletal receptor tyrosine-protein kinase Musk C00017726 C00018127 1 / 1
O60674 Tyrosine-protein kinase JAK2 Jakb C00017726 C00018127 5 / 1
O60285 NUAK family SNF1-like kinase 1 CAMK serine/threonine protein kinase NUAK subfamily C00017726 C00018127 0 / 0
O75676 Ribosomal protein S6 kinase alpha-4 CAMK serine/threonine protein kinase MSKB subfamily C00017726 C00018127 0 / 0
O15111 Inhibitor of nuclear factor kappa-B kinase subunit alpha Other serine/threonine protein kinase C00017726 C00018127 1 / 1
P08069 Insulin-like growth factor 1 receptor TK tyrosine-protein kinase INSR subfamily C00017726 C00018127 1 / 3
P52564 Dual specificity mitogen-activated protein kinase kinase 6 Ste7 C00017726 C00018127 0 / 0
P09619 Platelet-derived growth factor receptor beta Pdgfr C00017726 C00018127 5 / 1
P06213 Insulin receptor TK tyrosine-protein kinase INSR subfamily C00017726 C00018127 5 / 4
P34947 G protein-coupled receptor kinase 5 AGC serine/threonine protein kinase GRK subfamily C00017726 C00018127 0 / 0
Q96RG2 PAS domain-containing serine/threonine-protein kinase Pask C00017726 C00018127 0 / 0
P37173 TGF-beta receptor type-2 TKL dual-specificity kinase STKR type 2 subfamily C00018127 4 / 3
Q13523 Serine/threonine-protein kinase PRP4 homolog Enzyme C00018127 0 / 0
P20794 Serine/threonine-protein kinase MAK CMGC serine/threonine protein kinase MAK subfamily C00018127 1 / 0
Q14004 Cyclin-dependent kinase 13 Enzyme C00018127 0 / 0
P04626 Receptor tyrosine-protein kinase erbB-2 TK tyrosine-protein kinase EGFR subfamily C00018127 5 / 9
Q03164 Histone-lysine N-methyltransferase 2A Enzyme C00018127 1 / 2
Q00532 Cyclin-dependent kinase-like 1 CMGC serine/threonine protein kinase CDKL subfamily C00018127 0 / 0
P78356 Phosphatidylinositol 5-phosphate 4-kinase type-2 beta Kinase C00018127 0 / 0
Q12809 Potassium voltage-gated channel subfamily H member 2 KCNH, Kv10-12.x (Ether-a-go-go) C00018127 2 / 2
P46734 Dual specificity mitogen-activated protein kinase kinase 3 Ste7 C00018127 0 / 0
P57078 Receptor-interacting serine/threonine-protein kinase 4 TKL serine/threonine protein kinase RIPK subfamily C00018127 1 / 0
Q8NE63 Homeodomain-interacting protein kinase 4 CMGC serine/threonine protein kinase HIPK subfamily C00018127 0 / 0
P53671 LIM domain kinase 2 Limk C00018127 0 / 0
Q56UN5 Mitogen-activated protein kinase kinase kinase 19 STE serine/threonine protein kinase MEKK15 subfamily C00018127 0 / 0
Q92918 Mitogen-activated protein kinase kinase kinase kinase 1 STE serine/threonine protein kinase KHS subfamily C00018127 0 / 0
O14730 Serine/threonine-protein kinase RIO3 Rio3 C00018127 0 / 0
Q6P3R8 Serine/threonine-protein kinase Nek5 Nek C00018127 0 / 0
Q13873 Bone morphogenetic protein receptor type-2 TKL serine/threonine protein kinase STKR type 2 subfamily C00018127 2 / 1
Q9UQ88 Cyclin-dependent kinase 11A Pitslre C00018127 0 / 0
Q13164 Mitogen-activated protein kinase 7 CMGC serine/threonine protein kinase ERK5 subfamily C00018127 0 / 0
O60331 Phosphatidylinositol 4-phosphate 5-kinase type-1 gamma Enzyme C00018127 1 / 1
P35590 Tyrosine-protein kinase receptor Tie-1 Tie C00018127 0 / 0
P42679 Megakaryocyte-associated tyrosine-protein kinase Csk C00018127 0 / 0
P15056 Serine/threonine-protein kinase B-raf Raf C00018127 6 / 3
P06746 DNA polymerase beta Enzyme C00018127 0 / 0
Q9UBF8 Phosphatidylinositol 4-kinase beta Enzyme C00018127 0 / 0
P49798 Regulator of G-protein signaling 4 Unclassified protein C00018127 2 / 0
Q9UF33 Ephrin type-A receptor 6 Eph C00018127 0 / 0
O14976 Cyclin-G-associated kinase NAK serine/threonine protein kinase subfamily C00018127 0 / 0
Q9NSY1 BMP-2-inducible protein kinase NAK serine/threonine protein kinase subfamily C00018127 0 / 0
Q13163 Dual specificity mitogen-activated protein kinase kinase 5 Ste7 C00018127 0 / 0
Q13153 Serine/threonine-protein kinase PAK 1 STE serine/threonine protein kinase PAKA subfamily C00018127 0 / 0
Q9Y4K4 Mitogen-activated protein kinase kinase kinase kinase 5 STE serine/threonine protein kinase KHS subfamily C00018127 0 / 0
P41279 Mitogen-activated protein kinase kinase kinase 8 Ste11 C00018127 0 / 0
Q14164 Inhibitor of nuclear factor kappa-B kinase subunit epsilon Other serine/threonine protein kinase C00018127 0 / 0
Q9H1R3 Myosin light chain kinase 2, skeletal/cardiac muscle Mlck C00018127 1 / 0
Q13237 cGMP-dependent protein kinase 2 Pkg C00018127 0 / 0
P42336 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform Enzyme C00018127 9 / 1
O76039 Cyclin-dependent kinase-like 5 CMGC serine/threonine protein kinase CDKL subfamily C00018127 1 / 2
O15075 Serine/threonine-protein kinase DCLK1 CAMK serine/threonine protein kinase DCAMK1 C00018127 0 / 0
Q9Y2T6 G-protein coupled receptor 55 Lysophosphatidylinositol receptor C00018127 0 / 0
Q9BQI3 Eukaryotic translation initiation factor 2-alpha kinase 1 Hri C00018127 0 / 0
O94921 Cyclin-dependent kinase 14 Pftaire C00018127 0 / 0
Q9H0K1 Serine/threonine-protein kinase SIK2 CAMK serine/threonine protein kinase QIK subfamily C00018127 0 / 0
Q8TBX8 Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma Enzyme C00018127 0 / 0
Q00537 Cyclin-dependent kinase 17 Pctaire C00018127 0 / 0
P15428 15-hydroxyprostaglandin dehydrogenase [NAD(+)] Enzyme C00018127 2 / 2
O15118 Niemann-Pick C1 protein Unclassified protein C00018127 1 / 1
Q96QE3 ATPase family AAA domain-containing protein 5 Unclassified protein C00018127 0 / 0
Q6XUX3 Dual serine/threonine and tyrosine protein kinase Enzyme C00018127 0 / 0
Q9BX84 Transient receptor potential cation channel subfamily M member 6 Enzyme C00018127 1 / 1
Q9Y2U5 Mitogen-activated protein kinase kinase kinase 2 STE serine/threonine protein kinase MEKK2 subfamily C00018127 0 / 0
Q8WU08 Serine/threonine-protein kinase 32A AGC serine/threonine protein kinase YANK subfamily C00018127 0 / 0
P51151 Ras-related protein Rab-9A Unclassified protein C00018127 0 / 0
O75496 Geminin Unclassified protein C00018127 0 / 0
Q9UEW8 STE20/SPS1-related proline-alanine-rich protein kinase STE serine/threonine protein kinase FRAY subfamily C00018127 0 / 0
O95382 Mitogen-activated protein kinase kinase kinase 6 STE serine/threonine protein kinase ASK subfamily C00018127 0 / 0
Q9UPZ9 Serine/threonine-protein kinase ICK CMGC serine/threonine protein kinase MAK subfamily C00018127 1 / 1
Q6ZN16 Mitogen-activated protein kinase kinase kinase 15 STE serine/threonine protein kinase ASK subfamily C00018127 0 / 0
Q9NRM7 Serine/threonine-protein kinase LATS2 AGC serine/threonine protein kinase NDR C00018127 0 / 0
P17861 X-box-binding protein 1 Unclassified protein C00018127 1 / 0
O95819 Mitogen-activated protein kinase kinase kinase kinase 4 STE serine/threonine protein kinase MSN subfamily C00018127 0 / 0
Q9BWU1 Cyclin-dependent kinase 19 Cdk8 C00018127 0 / 0
O14578 Citron Rho-interacting kinase Crik C00018127 0 / 0
Q16637 Survival motor neuron protein Unclassified protein C00018127 4 / 1
Q04771 Activin receptor type-1 TKL serine/threonine protein kinase STKR1 subfamily C00018127 1 / 1
O00329 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform Enzyme C00018127 0 / 0
Q96Q40 Cyclin-dependent kinase 15 Pftaire C00018127 0 / 0
Q6DT37 Serine/threonine-protein kinase MRCK gamma AGC serine/threonine protein kinase GEK subfamily C00018127 0 / 0
Q9Y463 Dual specificity tyrosine-phosphorylation-regulated kinase 1B CMGC dual-specificity kinase DYRK1 C00018127 0 / 0
P49336 Cyclin-dependent kinase 8 Cdk8 C00018127 0 / 0
Q8WXR4 Myosin-IIIb STE serine/threonine protein kinase NINAC subfamily C00018127 0 / 0
Q8N752 Casein kinase I isoform alpha-like Ck1-a C00018127 0 / 0
Q92830 Histone acetyltransferase KAT2A Enzyme C00018127 0 / 0
O75716 Serine/threonine-protein kinase 16 NAK serine/threonine protein kinase subfamily C00018127 0 / 0
Q16512 Serine/threonine-protein kinase N1 Pkn C00018127 0 / 0
P33981 Dual specificity protein kinase TTK Ttk C00018127 0 / 0
Q8IXJ6 NAD-dependent protein deacetylase sirtuin-2 Enzyme C00018127 0 / 0
Q9HAZ1 Dual specificity protein kinase CLK4 Clk C00018127 0 / 0
Q59H18 Serine/threonine-protein kinase TNNI3K HH498 C00018127 0 / 0
Q00536 Cyclin-dependent kinase 16 CMGC serine/threonine protein kinase TAIRE subfamily C00018127 0 / 0
Q96EB6 NAD-dependent protein deacetylase sirtuin-1 Enzyme C00018127 0 / 0
Q8IY84 Serine/threonine-protein kinase NIM1 Nim1 C00018127 0 / 0
O94768 Serine/threonine-protein kinase 17B Dapk C00018127 0 / 0
Q9NYL2 Mitogen-activated protein kinase kinase kinase MLT TKL dual-specificity kinase MLK C00018127 0 / 0
P29597 Non-receptor tyrosine-protein kinase TYK2 Jakb C00018127 1 / 1
P37023 Serine/threonine-protein kinase receptor R3 TKL serine/threonine protein kinase STKR type 1 subfamily C00018127 1 / 1
Q07002 Cyclin-dependent kinase 18 Pctaire C00018127 0 / 0
Q12851 Mitogen-activated protein kinase kinase kinase kinase 2 STE serine/threonine protein kinase KHS subfamily C00018127 0 / 0
Q15046 Lysine--tRNA ligase Enzyme C00018127 2 / 1
Q15835 Rhodopsin kinase AGC serine/threonine protein kinase GRK subfamily C00018127 1 / 1
Q9Y616 Interleukin-1 receptor-associated kinase 3 Irak C00018127 1 / 0
Q6W5P4 Neuropeptide S receptor Neuropeptide receptor C00018127 1 / 0
Q9UQM7 Calcium/calmodulin-dependent protein kinase type II subunit alpha Camk2 C00018127 0 / 0
Q86UX6 Serine/threonine-protein kinase 32C AGC serine/threonine protein kinase YANK C00018127 0 / 0
P21453 Sphingosine 1-phosphate receptor 1 EDG receptor C00018127 0 / 0
Q8IVH8 Mitogen-activated protein kinase kinase kinase kinase 3 STE serine/threonine protein kinase KHS subfamily C00018127 0 / 0
Q8NFD2 Ankyrin repeat and protein kinase domain-containing protein 1 TKL serine/threonine protein kinase RIPK subfamily C00018127 0 / 0
Q99759 Mitogen-activated protein kinase kinase kinase 3 Mekk2 C00018127 0 / 0
O75385 Serine/threonine-protein kinase ULK1 ULK serine/threonine protein kinase C00018127 0 / 0
P27695 DNA-(apurinic or apyrimidinic site) lyase Enzyme C00018127 0 / 0
P00352 Retinal dehydrogenase 1 Enzyme C00018127 0 / 0
Q12852 Mitogen-activated protein kinase kinase kinase 12 Enzyme C00018127 0 / 0
P21860 Receptor tyrosine-protein kinase erbB-3 TK tyrosine-protein kinase EGFR subfamily C00018127 1 / 2
Q5S007 Leucine-rich repeat serine/threonine-protein kinase 2 TKL serine/threonine protein kinase LRRK subfamily C00018127 2 / 2
O75460 Serine/threonine-protein kinase/endoribonuclease IRE1 Enzyme C00018127 0 / 0
O95747 Serine/threonine-protein kinase OSR1 STE serine/threonine protein kinase FRAY subfamily C00018127 0 / 0
Q52WX2 Serine/threonine-protein kinase SBK1 NKF1 serine/threonine protein kinase subfamily C00018127 0 / 0
P45985 Dual specificity mitogen-activated protein kinase kinase 4 Ste7 C00018127 0 / 0
P36507 Dual specificity mitogen-activated protein kinase kinase 2 Ste7 C00018127 1 / 1
P49674 Casein kinase I isoform epsilon Ck1 C00018127 0 / 0
P23458 Tyrosine-protein kinase JAK1 Jakb C00018127 0 / 0
O95977 Sphingosine 1-phosphate receptor 4 EDG receptor C00018127 0 / 0
Q8TD19 Serine/threonine-protein kinase Nek9 Nek C00018127 0 / 0
Q96NX5 Calcium/calmodulin-dependent protein kinase type 1G Camk1 C00018127 0 / 0
Q99640 Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase Dual-specificity kinase WEE subfamily C00018127 0 / 0
Q9H2G2 STE20-like serine/threonine-protein kinase STE serine/threonine protein kinase SLK subfamily C00018127 0 / 0
Q9NRP7 Serine/threonine-protein kinase 36 ULK serine/threonine protein kinase subfamily C00018127 0 / 0
Q08345 Epithelial discoidin domain-containing receptor 1 Ddr C00018127 0 / 0
Q9Y2H1 Serine/threonine-protein kinase 38-like AGC serine/threonine protein kinase NDR subfamily C00018127 0 / 0
O75747 Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit gamma Enzyme C00018127 0 / 0
Q9Y2K2 Serine/threonine-protein kinase SIK3 CAMK serine/threonine protein kinase QIK subfamily C00018127 0 / 0
Q9P289 Serine/threonine-protein kinase MST4 STE serine/threonine protein kinase YSK subfamily C00018127 0 / 0
P48736 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform Enzyme C00018127 0 / 0
P32298 G protein-coupled receptor kinase 4 AGC serine/threonine protein kinase GRK subfamily C00018127 0 / 0
P49759 Dual specificity protein kinase CLK1 Clk C00018127 0 / 0
Q13233 Mitogen-activated protein kinase kinase kinase 1 Ste11 C00018127 1 / 0
O14746 Telomerase reverse transcriptase Enzyme C00018127 5 / 5
Q9H3Y6 Tyrosine-protein kinase Srms TK tyrosine-protein kinase SRM subfamily C00018127 0 / 0
Q9H093 NUAK family SNF1-like kinase 2 CAMK serine/threonine protein kinase NUAK subfamily C00018127 0 / 0
P29376 Leukocyte tyrosine kinase receptor Alk C00018127 0 / 0
Q9C098 Serine/threonine-protein kinase DCLK3 CAMK serine/threonine protein kinase DCAMK1 C00018127 0 / 0
Q9BVS4 Serine/threonine-protein kinase RIO2 Rio2 C00018127 0 / 0
Q99558 Mitogen-activated protein kinase kinase kinase 14 Unique STE serine/threonine protein kinase C00018127 0 / 0
Q96PY6 Serine/threonine-protein kinase Nek1 Nek C00018127 1 / 1
O00506 Serine/threonine-protein kinase 25 STE serine/threonine protein kinase YSK subfamily C00018127 0 / 0
Q9Y6R4 Mitogen-activated protein kinase kinase kinase 4 Ste11 C00018127 0 / 0
P0C264 Putative uncharacterized serine/threonine-protein kinase SgK110 NKF1 serine/threonine protein kinase subfamily C00018127 0 / 0
Q13705 Activin receptor type-2B TKL serine/threonine protein kinase STKR type 2 subfamily C00018127 1 / 1
Q9UKI8 Serine/threonine-protein kinase tousled-like 1 TLK serine/threonine protein kinase C00018127 0 / 0
Q9NRH2 SNF-related serine/threonine-protein kinase Enzyme C00018127 0 / 0
Q2M2I8 AP2-associated protein kinase 1 NAK serine/threonine protein kinase subfamily C00018127 0 / 0
P36894 Bone morphogenetic protein receptor type-1A TKL serine/threonine protein kinase STKR type 1 subfamily C00018127 3 / 2
Q13470 Non-receptor tyrosine-protein kinase TNK1 Ack C00018127 0 / 0
Q15569 Dual specificity testis-specific protein kinase 1 TKL dual-specificity kinase TESK subfamily C00018127 0 / 0
Q15750 TGF-beta-activated kinase 1 and MAP3K7-binding protein 1 Unclassified protein C00018127 0 / 0
Q16288 NT-3 growth factor receptor Trk C00018127 0 / 1
Q9P2K8 Eukaryotic translation initiation factor 2-alpha kinase 4 Unique STE serine/threonine protein kinase C00018127 0 / 0
Q13546 Receptor-interacting serine/threonine-protein kinase 1 TKL serine/threonine protein kinase RIPK subfamily C00018127 0 / 0
O00238 Bone morphogenetic protein receptor type-1B TKL serine/threonine protein kinase STKR type 1 subfamily C00018127 2 / 2
P0C1S8 Wee1-like protein kinase 2 Wee1 C00018127 0 / 0
P30291 Wee1-like protein kinase WEE serine/threonine protein kinase subfamily C00018127 0 / 0
Q96D53 Uncharacterized aarF domain-containing protein kinase 4 Atypical serine/threonine protein kinase ABC1-A C00018127 0 / 0
Q96L34 MAP/microtubule affinity-regulating kinase 4 CAMK serine/threonine protein kinase MARK subfamily C00018127 0 / 0
Q16659 Mitogen-activated protein kinase 6 CMGC serine/threonine protein kinase ERK3 subfamily C00018127 0 / 0
Q9UKE5 TRAF2 and NCK-interacting protein kinase STE serine/threonine protein kinase MSN subfamily C00018127 0 / 0
Q9BRS2 Serine/threonine-protein kinase RIO1 Rio1 C00018127 0 / 0
O95835 Serine/threonine-protein kinase LATS1 AGC serine/threonine protein kinase NDR C00018127 0 / 0
P31152 Mitogen-activated protein kinase 4 CMGC serine/threonine protein kinase ERK3 subfamily C00018127 0 / 0
Q9NY57 Serine/threonine-protein kinase 32B AGC serine/threonine protein kinase YANK C00018127 0 / 0
B2RXH2 Lysine-specific demethylase 4E Enzyme C00018127 0 / 0
P46063 ATP-dependent DNA helicase Q1 Enzyme C00018127 0 / 0
Q96KQ7 Histone-lysine N-methyltransferase EHMT2 Enzyme C00018127 0 / 0
O15197 Ephrin type-B receptor 6 Unclassified protein C00018127 0 / 0
Q86YV6 Myosin light chain kinase family member 4 Mlck C00018127 0 / 0
Q8IVW4 Cyclin-dependent kinase-like 3 CMGC serine/threonine protein kinase CDKL subfamily C00018127 0 / 0
Q9Y2H9 Microtubule-associated serine/threonine-protein kinase 1 AGC serine/threonine protein kinase MAST C00018127 0 / 0
O00255 Menin Unclassified protein C00018127 2 / 5
Q8NEV4 Myosin-IIIa STE serine/threonine protein kinase NINAC subfamily C00018127 1 / 1
O00444 Serine/threonine-protein kinase PLK4 PLK serine/threonine protein kinase subfamily C00018127 0 / 0
Q8NI60 Chaperone activity of bc1 complex-like, mitochondrial Enzyme C00018127 1 / 2
O00750 Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta Enzyme C00018127 0 / 0
Q8TDR2 Serine/threonine-protein kinase 35 Nkf4 C00018127 0 / 0
Q32MK0 Myosin light chain kinase 3 Mlck C00018127 0 / 0
P42338 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform Enzyme C00018127 0 / 0
P48729 Casein kinase I isoform alpha Ck1 C00018127 0 / 0
Q92772 Cyclin-dependent kinase-like 2 CMGC serine/threonine protein kinase CDKL subfamily C00018127 0 / 0
P08183 Multidrug resistance protein 1 drug C00018127 1 / 0
P21127 Cyclin-dependent kinase 11B Pitslre C00018127 0 / 0
P51957 Serine/threonine-protein kinase Nek4 Nek C00018127 0 / 0
Q99755 Phosphatidylinositol 4-phosphate 5-kinase type-1 alpha Kinase C00018127 0 / 0
P42574 Caspase-3 C14 C00018127 0 / 0
P27037 Activin receptor type-2A TKL serine/threonine protein kinase STKR type 2 subfamily C00018127 0 / 0
O43283 Mitogen-activated protein kinase kinase kinase 13 Lzk C00018127 0 / 0
Q15208 Serine/threonine-protein kinase 38 AGC serine/threonine protein kinase NDR C00018127 0 / 0
O14936 Peripheral plasma membrane protein CASK Enzyme C00018127 2 / 2
P57058 Hormonally up-regulated neu tumor-associated kinase Enzyme C00018127 0 / 0
P02545 Prelamin-A/C Unclassified protein C00018127 11 / 10

82 Gene in CTD interactions

gene gene name gene description KNApSAcK metabolite in interactions
596 BCL2, Bcl-2, PPP1R50 B-cell CLL/lymphoma 2 C00018127 C00024753
7157 TP53, BCC7, LFS1, P53, TRP53 tumor protein p53 C00018127 C00024753
142 PARP1, ADPRT, ADPRT_1, ADPRT1, ARTD1, PARP, PARP-1, PPOL, pADPRT-1 poly (ADP-ribose) polymerase 1 (EC:2.4.2.30) C00018127 C00024753
598 BCL2L1, BCL-XL/S, BCL2L, BCLX, BCLXL, BCLXS, Bcl-X, PPP1R52, bcl-xL, bcl-xS BCL2-like 1 C00018127 C00024753
637 BID, FP497 BH3 interacting domain death agonist C00018127 C00024753
332 BIRC5, API4, EPR-1 baculoviral IAP repeat containing 5 C00018127 C00024753
835 CASP2, CASP-2, ICH1, NEDD-2, NEDD2, PPP1R57 caspase 2, apoptosis-related cysteine peptidase (EC:3.4.22.55) C00018127 C00024753
836 CASP3, CPP32, CPP32B, SCA-1 caspase 3, apoptosis-related cysteine peptidase (EC:3.4.22.56) C00018127 C00024753
841 CASP8, ALPS2B, CAP4, Casp-8, FLICE, MACH, MCH5 caspase 8, apoptosis-related cysteine peptidase (EC:3.4.22.61) C00018127 C00024753
842 CASP9, APAF-3, APAF3, ICE-LAP6, MCH6, PPP1R56 caspase 9, apoptosis-related cysteine peptidase (EC:3.4.22.62) C00018127 C00024753
4170 MCL1, BCL2L3, EAT, MCL1-ES, MCL1L, MCL1S, Mcl-1, TM, bcl2-L-3, mcl1/EAT myeloid cell leukemia sequence 1 (BCL2-related) C00018127 C00024753
5595 MAPK3, ERK-1, ERK1, ERT2, HS44KDAP, HUMKER1A, P44ERK1, P44MAPK, PRKM3, p44-ERK1, p44-MAPK mitogen-activated protein kinase 3 (EC:2.7.11.24) C00018127 C00024753
5594 MAPK1, ERK, ERK2, ERT1, MAPK2, P42MAPK, PRKM1, PRKM2, p38, p40, p41, p41mapk mitogen-activated protein kinase 1 (EC:2.7.11.24) C00018127 C00024753
3689 ITGB2, CD18, LAD, LCAMB, LFA-1, MAC-1, MF17, MFI7 integrin, beta 2 (complement component 3 receptor 3 and 4 subunit) C00018127
5604 MAP2K1, CFC3, MAPKK1, MEK1, MKK1, PRKMK1 mitogen-activated protein kinase kinase 1 (EC:2.7.12.2) C00024753
5605 MAP2K2, CFC4, MAPKK2, MEK2, MKK2, PRKMK2 mitogen-activated protein kinase kinase 2 (EC:2.7.12.2) C00024753
1111 CHEK1, CHK1 checkpoint kinase 1 (EC:2.7.11.1) C00024753
983 CDK1, CDC2, CDC28A, P34CDC2 cyclin-dependent kinase 1 (EC:2.7.11.23 2.7.11.22) C00024753
5599 MAPK8, JNK, JNK-46, JNK1, JNK1A2, JNK21B1/2, PRKM8, SAPK1, SAPK1c mitogen-activated protein kinase 8 (EC:2.7.11.24) C00024753
595 CCND1, BCL1, D11S287E, PRAD1, U21B31 cyclin D1 C00024753
4288 MKI67, KIA, MIB-1 marker of proliferation Ki-67 C00024753
9131 AIFM1, AIF, CMTX4, COWCK, COXPD6, PDCD8 apoptosis-inducing factor, mitochondrion-associated, 1 C00024753
5175 PECAM1, CD31, CD31/EndoCAM, GPIIA', PECA1, PECAM-1, endoCAM platelet/endothelial cell adhesion molecule 1 C00024753
5894 RAF1, CRAF, NS5, Raf-1, c-Raf v-raf-1 murine leukemia viral oncogene homolog 1 (EC:2.7.11.1) C00024753
5925 RB1, OSRC, RB, p105-Rb, pRb, pp110 retinoblastoma 1 C00024753
6667 SP1 Sp1 transcription factor C00024753
412 STS, ARSC, ARSC1, ASC, ES, SSDD, XLI steroid sulfatase (microsomal), isozyme S (EC:3.1.6.2) C00024753
573 BAG1, BAG-1, HAP, RAP46 BCL2-associated athanogene C00024753
331 XIAP, API3, BIRC4, IAP-3, ILP1, MIHA, XLP2, hIAP-3, hIAP3 X-linked inhibitor of apoptosis C00024753
8647 ABCB11, ABC16, BRIC2, BSEP, PFIC-2, PFIC2, PGY4, SPGP ATP-binding cassette, sub-family B (MDR/TAP), member 11 C00018127
43 ACHE, ACEE, ARACHE, N-ACHE, YT acetylcholinesterase (EC:3.1.1.7) C00018127
133 ADM, AM adrenomedullin C00018127
207 AKT1, AKT, CWS6, PKB, PKB-ALPHA, PRKBA, RAC, RAC-ALPHA v-akt murine thymoma viral oncogene homolog 1 (EC:2.7.11.1) C00018127
351 APP, AAA, ABETA, ABPP, AD1, APPI, CTFgamma, CVAP, PN-II, PN2 amyloid beta (A4) precursor protein C00018127
9140 ATG12, APG12, APG12L, FBR93, HAPG12 autophagy related 12 C00018127
10533 ATG7, APG7-LIKE, APG7L, GSA7 autophagy related 7 C00018127
9531 BAG3, BAG-3, BIS, CAIR-1, MFM6 BCL2-associated athanogene 3 C00018127
9530 BAG4, BAG-4, SODD BCL2-associated athanogene 4 C00018127
7917 BAG6, BAG-6, BAT3, D6S52E, G3 BCL2-associated athanogene 6 C00018127
581 BAX, BCL2L4 BCL2-associated X protein C00018127
8678 BECN1, ATG6, VPS30, beclin1 beclin 1, autophagy related C00018127
330 BIRC3, AIP1, API2, CIAP2, HAIP1, HIAP1, MALT2, MIHC, RNF49, c-IAP2 baculoviral IAP repeat containing 3 C00018127
834 CASP1, ICE, IL1BC, P45 caspase 1, apoptosis-related cysteine peptidase (EC:3.4.22.36) C00018127
843 CASP10, ALPS2, FLICE2, MCH4 caspase 10, apoptosis-related cysteine peptidase (EC:3.4.22.63) C00018127
840 CASP7, CASP-7, CMH-1, ICE-LAP3, LICE2, MCH3 caspase 7, apoptosis-related cysteine peptidase (EC:3.4.22.60) C00018127
940 CD28, Tp44 CD28 molecule C00018127
1026 CDKN1A, CAP20, CDKN1, CIP1, MDA-6, P21, SDI1, WAF1, p21CIP1 cyclin-dependent kinase inhibitor 1A (p21, Cip1) C00018127
1027 CDKN1B, CDKN4, KIP1, MEN1B, MEN4, P27KIP1 cyclin-dependent kinase inhibitor 1B (p27, Kip1) C00018127
1128 CHRM1, HM1, M1, M1R cholinergic receptor, muscarinic 1 C00018127
1129 CHRM2, HM2 cholinergic receptor, muscarinic 2 C00018127
1385 CREB1, CREB cAMP responsive element binding protein 1 C00018127
1437 CSF2, GMCSF colony stimulating factor 2 (granulocyte-macrophage) C00018127
1543 CYP1A1, AHH, AHRR, CP11, CYP1, P1-450, P450-C, P450DX cytochrome P450, family 1, subfamily A, polypeptide 1 (EC:1.14.14.1) C00018127
1576 CYP3A4, CP33, CP34, CYP3A, CYP3A3, CYPIIIA3, CYPIIIA4, HLP, NF-25, P450C3, P450PCN1 cytochrome P450, family 3, subfamily A, polypeptide 4 (EC:1.14.13.67 1.14.13.97 1.14.13.32 1.14.13.157) C00018127
1950 EGF, HOMG4, URG epidermal growth factor C00018127
1956 EGFR, ERBB, ERBB1, HER1, PIG61, mENA epidermal growth factor receptor (EC:2.7.10.1) C00018127
2152 F3, CD142, TF, TFA coagulation factor III (thromboplastin, tissue factor) C00018127
2729 GCLC, GCL, GCS, GLCL, GLCLC glutamate-cysteine ligase, catalytic subunit (EC:6.3.2.2) C00018127
2730 GCLM, GLCLR glutamate-cysteine ligase, modifier subunit (EC:6.3.2.2) C00018127
3162 HMOX1, HMOX1D, HO-1, HSP32, bK286B10 heme oxygenase (decycling) 1 (EC:1.14.99.3) C00018127
3567 IL5, EDF, IL-5, TRF interleukin 5 (colony-stimulating factor, eosinophil) C00018127
56616 DIABLO, DFNA64, SMAC diablo, IAP-binding mitochondrial protein C00024753
4137 MAPT, DDPAC, FTDP-17, MAPTL, MSTD, MTBT1, MTBT2, PPND, TAU microtubule-associated protein tau C00018127
4139 MARK1, MARK, Par-1c, Par1c MAP/microtubule affinity-regulating kinase 1 (EC:2.7.11.1 2.7.11.26) C00018127
4193 MDM2, ACTFS, HDMX, hdm2 MDM2 oncogene, E3 ubiquitin protein ligase C00018127
4318 MMP9, CLG4B, GELB, MANDP2, MMP-9 matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase) (EC:3.4.24.35) C00018127
4609 MYC, MRTL, MYCC, bHLHe39, c-Myc v-myc avian myelocytomatosis viral oncogene homolog C00018127
4922 NTS, NMN-125, NN, NT, NT/N, NTS1 neurotensin C00018127
5530 PPP3CA, CALN, CALNA, CALNA1, CCN1, CNA1, PPP2B protein phosphatase 3, catalytic subunit, alpha isozyme (EC:3.1.3.16) C00018127
5578 PRKCA, AAG6, PKC-alpha, PKCA, PRKACA protein kinase C, alpha (EC:2.7.11.13) C00018127
5580 PRKCD, MAY1, PKCD, nPKC-delta protein kinase C, delta (EC:2.7.10.2 2.7.11.13) C00018127
5664 PSEN2, AD3L, AD4, CMD1V, PS2, STM2 presenilin 2 (Alzheimer disease 4) C00018127
5743 PTGS2, COX-2, COX2, GRIPGHS, PGG/HS, PGHS-2, PHS-2, hCox-2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) (EC:1.14.99.1) C00018127
57468 SLC12A5, KCC2 solute carrier family 12 (potassium/chloride transporter), member 5 C00018127
114571 SLC22A9, HOAT4, OAT4, OAT7, UST3H, ust3 solute carrier family 22 (organic anion transporter), member 9 C00018127
8884 SLC5A6, SMVT solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6 C00018127
6622 SNCA, NACP, PARK1, PARK4, PD1 synuclein, alpha (non A4 component of amyloid precursor) C00018127
6774 STAT3, APRF, HIES signal transducer and activator of transcription 3 (acute-phase response factor) C00018127
10492 SYNCRIP, GRY-RBP, GRYRBP, HNRNPQ, HNRPQ1, NSAP1, PP68, hnRNP-Q synaptotagmin binding, cytoplasmic RNA interacting protein C00018127
7421 VDR, NR1I1 vitamin D (1,25- dihydroxyvitamin D3) receptor C00018127
7422 VEGFA, MVCD1, VEGF, VPF vascular endothelial growth factor A C00018127
7490 WT1, AWT1, EWS-WT1, GUD, NPHS4, WAGR, WIT-2, WT33 Wilms tumor 1 C00018127

Related Diseases

Diseases related to proteins in ChEMBL interactions

OMIM (200)

OMIM preferred title UniProt
#613762 46,xy sex reversal 6; srxy6 Q13233
#100800 Achondroplasia; ach P22607
#615224 Advanced sleep phase syndrome, familial, 2; fasps2 P48730
#300755 Agammaglobulinemia, x-linked; xla Q06187
#207410 Antley-bixler syndrome without genital anomalies or disordered steroidogenesis; abs2 P21802
#613780 Aortic aneurysm, familial thoracic 7; aat7 Q15746
#101200 Apert syndrome P21802
#609135 Aplastic anemia O14746
#608584 Asthma-related traits, susceptibility to, 2 Q6W5P4
#611064 Asthma-related traits, susceptibility to, 5 Q9Y616
#615007 Basal ganglia calcification, idiopathic, 4; ibgc4 P09619
#123790 Beare-stevenson cutis gyrata syndrome; bstvs P21802
#614592 Bent bone dysplasia syndrome; bbds P21802
#109800 Bladder cancer P22607
#112600 Brachydactyly, type a2; bda2 O00238
#114480 Breast cancer O96017
P31749
P42336
#600880 Budd-chiari syndrome; bdchs O60674
#610474 Camptodactyly, tall stature, and hearing loss syndrome P22607
#115150 Cardiofaciocutaneous syndrome 1; cfc1 P15056
#615279 Cardiofaciocutaneous syndrome 3; cfc3 Q02750
#615280 Cardiofaciocutaneous syndrome 4; cfc4 P36507
#115200 Cardiomyopathy, dilated, 1a; cmd1a P02545
#212112 Cardiomyopathy, dilated, with hypergonadotropic hypogonadism P02545
#192600 Cardiomyopathy, familial hypertrophic, 1; cmh1 Q9H1R3
#600858 Cardiomyopathy, familial hypertrophic, 6; cmh6 Q9UGJ0
#116600 Cataract 6, multiple types; ctrct6 P29317
#209880 Central hypoventilation syndrome, congenital; cchs P07949
#603956 Cervical cancer P22607
#605588 Charcot-marie-tooth disease, axonal, type 2b1; cmt2b1 P02545
#613641 Charcot-marie-tooth disease, recessive intermediate b; cmtrib Q15046
#609441 Chondrodysplasia, acromesomelic, with genital anomalies O00238
#612242 Chromosome 10q23 deletion syndrome P36894
#613630 Cocoon syndrome O15111
#612016 Coenzyme q10 deficiency, primary, 4; coq10d4 Q8NI60
#303600 Coffin-lowry syndrome; cls P51812
#614331 Colorectal cancer, hereditary nonpolyposis, type 6; hnpcc6 P37173
#114500 Colorectal cancer; crc P07949
P15056
P29320
P31749
P42336
#612918 Congenital lipomatous overgrowth, vascular malformations, and epidermal nevi P42336
#615108 Cowden syndrome 5; cws5 P42336
#615109 Cowden syndrome 6; cws6 P31749
#123500 Crouzon syndrome P21802
#612247 Crouzon syndrome with acanthosis nigricans; can P22607
#607101 Deafness, autosomal recessive 30; dfnb30 Q8NEV4
#613916 Deafness, autosomal recessive 89; dfnb89 Q15046
#610549 Diabetes mellitus, insulin-resistant, with acanthosis nigricans P06213
#125853 Diabetes mellitus, noninsulin-dependent; niddm P06213
P31751
#119900 Digital clubbing, isolated congenital P15428
#246200 Donohue syndrome P06213
#613989 Dyskeratosis congenita, autosomal dominant, 2; dkca2 O14746
#181350 Emery-dreifuss muscular dystrophy 2, autosomal dominant; edmd2 P02545
#612651 Endocrine-cerebroosteodysplasia; eco Q9UPZ9
#300672 Epileptic encephalopathy, early infantile, 2; eiee2 O76039
#133239 Esophageal cancer P37173
#300422 Fg syndrome 4; fgs4 O14936
#135100 Fibrodysplasia ossificans progressiva; fop Q04771
#600274 Frontotemporal dementia; ftd P10636
#613659 Gastric cancer P04626
#137215 Gastric cancer, hereditary diffuse; hdgc P04626
#606764 Gastrointestinal stromal tumor; gist P10721
P16234
#177700 Glaucoma 1, open angle, p; glc1p Q9UHD2
#137800 Glioma susceptibility 1; glm1 P04626
#306000 Glycogen storage disease ixa1; gsd9a1 P46019
#261750 Glycogen storage disease ixb; gsd9b Q93100
#613027 Glycogen storage disease ixc; gsd9c P15735
#261740 Glycogen storage disease of heart, lethal congenital Q9UGJ0
#300559 Glycogen storage disease, type ixd; gsd9d P46020
#605130 Hairy elbows, short stature, facial dysmorphism, and developmental delay Q03164
#610140 Heart-hand syndrome, slovenian type P02545
#602089 Hemangioma, capillary infantile P35916
P35968
#114550 Hepatocellular carcinoma P08581
P42336
#613751 Heterotaxy, visceral, 4, autosomal; htx4 Q13705
#142623 Hirschsprung disease, susceptibility to, 1; hscr1 P07949
#176670 Hutchinson-gilford progeria syndrome; hgps P02545
#607685 Hypereosinophilic syndrome, idiopathic; hes P16234
#602485 Hyperinsulinemic hypoglycemia, familial, 3; hhf3 P35557
#609968 Hyperinsulinemic hypoglycemia, familial, 5; hhf5 P06213
#145000 Hyperparathyroidism 1; hrpt1 O00255
#259100 Hypertrophic osteoarthropathy, primary, autosomal recessive, 1; phoar1 P15428
#146000 Hypochondroplasia; hch P22607
#147950 Hypogonadotropic hypogonadism 2 with or without anosmia; hh2 P11362
#240900 Hypoinsulinemic hypoglycemia with hemihypertrophy; hihghh P31751
#602014 Hypomagnesemia 1, intestinal; homg1 Q9BX84
#612244 Inflammatory bowel disease 13; ibd13 P08183
#256800 Insensitivity to pain, congenital, with anhidrosis; cipa P04629
#270450 Insulin-like growth factor i, resistance to P08069
#610799 Invasive pneumococcal disease, recurrent isolated, 1; ipd1 Q9NWZ3
#607676 Irak4 deficiency Q9NWZ3
#307200 Isolated growth hormone deficiency, type iii; ighd3 Q06187
#123150 Jackson-weiss syndrome; jws P21802
#607785 Juvenile myelomonocytic leukemia; jmml P09619
#174900 Juvenile polyposis syndrome; jps P36894
#182000 Keratosis, seborrheic P22607
P42336
#149730 Lacrimoauriculodentodigital syndrome; ladd P21802
P22607
#611554 Leopard syndrome 2 P04049
#613707 Leopard syndrome 3 P15056
#607598 Lethal congenital contracture syndrome 2; lccs2 P21860
#611369 Lethal congenital contracture syndrome 3; lccs3 O60331
#601626 Leukemia, acute myeloid; aml O60674
P09619
P10721
P36888
#608232 Leukemia, chronic myeloid; cml P00519
#221820 Leukoencephalopathy, diffuse hereditary, with spheroids; hdls P07333
#609265 Li-fraumeni syndrome 2; lfs2 O96017
#151660 Lipodystrophy, familial partial, type 2; fpld2 P02545
#609192 Loeys-dietz syndrome, type 1a; lds1a P36897
#610168 Loeys-dietz syndrome, type 1b; lds1b P37173
#608967 Loeys-dietz syndrome, type 2a; lds2a P36897
#610380 Loeys-dietz syndrome, type 2b; lds2b P37173
#613688 Long qt syndrome 2; lqt2 Q12809
#211980 Lung cancer P00533
P04626
P15056
#153100 Lymphedema, hereditary, ia P35916
#605027 Lymphoma, non-hodgkin, familial P15056
#613011 Lymphoproliferative syndrome 1; lpfs1 Q08881
#612371 Major affective disorder 7; mafd7 P17861
#248370 Mandibuloacral dysplasia with type a lipodystrophy; mada P02545
#613375 Maturity-onset diabetes of the young, type 11; mody11 P51451
#125851 Maturity-onset diabetes of the young, type 2; mody2 P35557
#606391 Maturity-onset diabetes of the young; mody P35557
#602501 Megalencephaly-capillary malformation-polymicrogyria syndrome; mcap P42336
#603387 Megalencephaly-polymicrogyria-polydactyly-hydrocephalus syndrome; mpph P42336
Q9Y243
#609048 Melanoma, cutaneous malignant, susceptibility to, 3; cmm3 P11802
#615134 Melanoma, cutaneous malignant, susceptibility to, 9; cmm9 O14746
#300749 Mental retardation and microcephaly with pontine and cerebellar hypoplasia; micpch O14936
#614104 Mental retardation, autosomal dominant 7; mrd7 Q13627
#300844 Mental retardation, x-linked 19; mrx19 P51812
#300558 Mental retardation, x-linked 30; mrx30 O75914
#602849 Muenke syndrome; mnkes P22607
#131100 Multiple endocrine neoplasia, type i; men1 O00255
#171400 Multiple endocrine neoplasia, type iia; men2a P07949
#162300 Multiple endocrine neoplasia, type iib; men2b P07949
#132800 Multiple self-healing squamous epithelioma, susceptibility to; msse P36897
#613205 Muscular dystrophy, congenital, lmna-related P02545
#159001 Muscular dystrophy, limb-girdle, type 1b; lgmd1b P02545
#608931 Myasthenic syndrome, congenital, associated with acetylcholine receptor deficiency O15146
#254450 Myelofibrosis O60674
#254500 Myeloma, multiple P22607
P24385
#131440 Myeloproliferative disorder, chronic, with eosinophilia P09619
#228550 Myofibromatosis, infantile, 1; imf1 P09619
#160900 Myotonic dystrophy 1; dm1 Q09013
#613014 Neuroblastoma, susceptibility to, 3; nblst3 Q9UM73
#162900 Nevus, epidermal P22607
#257220 Niemann-pick disease, type c1; npc1 O15118
#611553 Noonan syndrome 5; ns5 P04049
#613706 Noonan syndrome 7; ns7 P15056
#613886 Obesity, hyperphagia, and developmental delay Q16620
#613411 Oguchi disease 2 Q15835
#259500 Osteogenic sarcoma O96017
#166250 Osteoglophonic dysplasia; ogd P11362
#167000 Ovarian cancer P04626
P42336
#607060 Parkinson disease 8, autosomal dominant; park8 Q5S007
#168600 Parkinson disease, late-onset; pd Q5S007
#260540 Parkinson-dementia syndrome P10636
#175200 Peutz-jeghers syndrome; pjs Q15831
#101600 Pfeiffer syndrome P11362
P21802
#171300 Pheochromocytoma P07949
#172700 Pick disease of brain P10636
#172800 Piebald trait; pbt P10721
#262190 Pineal hyperplasia, insulin-resistant diabetes mellitus, and somatic abnormalities P06213
#263300 Polycythemia vera; pv O60674
#610069 Polyposis syndrome, hereditary mixed, 2; hmps2 P36894
#263650 Popliteal pterygium syndrome, lethal type P57078
#176807 Prostate cancer O96017
P29323
#603688 Prostate cancer/brain cancer susceptibility P29323
#176920 Proteus syndrome P31749
#614742 Pulmonary fibrosis and/or bone marrow failure, telomere-related, 1; pfbmft1 O14746
#178500 Pulmonary fibrosis, idiopathic; ipf O14746
#178600 Pulmonary hypertension, primary, 1; pph1 Q13873
#265450 Pulmonary venoocclusive disease 1, autosomal dominant; pvod1 Q13873
#191830 Renal adysplasia P07949
#605074 Renal cell carcinoma, papillary, 1; rccp1 P08581
#275210 Restrictive dermopathy, lethal P02545
#613862 Retinitis pigmentosa 38; rp38 Q12866
#614181 Retinitis pigmentosa 62; rp62 P20794
#609579 Scaphocephaly, maxillary retrusion, and mental retardation P21802
#604906 Schizophrenia 9; sczd9 P49798
#181500 Schizophrenia; sczd P49798
#269840 Selective t-cell defect; stcd P43403
#600802 Severe combined immunodeficiency, autosomal recessive, t cell-negative, b cell-positive, nk cell-negative P52333
#609620 Short qt syndrome 1; sqt1 Q12809
#263520 Short-rib thoracic dysplasia 6 with or without polydactyly; srtd6 Q96PY6
#243060 Spermatogenic failure 5; spgf5 Q9UQB9
#253300 Spinal muscular atrophy, type i; sma1 Q16637
#253550 Spinal muscular atrophy, type ii; sma2 Q16637
#253400 Spinal muscular atrophy, type iii; sma3 Q16637
#271150 Spinal muscular atrophy, type iv; sma4 Q16637
#605361 Spinocerebellar ataxia 14; sca14 P05129
#271665 Spondylometaepiphyseal dysplasia, short limb-hand type Q16832
%612223 Stature quantitative trait locus 11; stqtl11 Q00534
#601367 Stroke, ischemic P24723
#601104 Supranuclear palsy, progressive, 1; psnp1 P10636
#614868 T-cell immunodeficiency, recurrent infections, and autoimmunity with or without cardiac malformations; tiiac Q13043
#600376 Telangiectasia, hereditary hemorrhagic, type 2; hht2 P37023
#273300 Testicular germ cell tumor; tgct O94804
P10721
P22607
Q15831
#187600 Thanatophoric dysplasia, type i; td1 P22607
#187601 Thanatophoric dysplasia, type ii; td2 P22607
#614521 Thrombocythemia 3; thcyt3 O60674
#155240 Thyroid carcinoma, familial medullary; mtc P07949
#188550 Thyroid carcinoma, papillary P04629
P07949
#190440 Trigonocephaly 1; trigno1 P11362
#611521 Tyrosine kinase 2 deficiency P29597
#600195 Venous malformations, multiple cutaneous and mucosal; vmcm Q02763
#194200 Wolff-parkinson-white syndrome Q9UGJ0

KEGG DISEASE (129)

KEGG name UniProt
H00468 Acromesomelic dysplasia with genital anomalies O00238 (related)
H00482 Brachydactyly O00238 (related)
H00033 Adrenal carcinoma O00255 (related)
H00034 Carcinoid O00255 (related)
H00045 Malignant islet cell carcinoma O00255 (related)
H00246 Primary hyperparathyroidism O00255 (related)
H01102 Pituitary adenomas O00255 (related)
H00764 Cri du chat syndrome O14746 (related)
H01132 Aplastic anemia (AA) O14746 (related)
H01299 Idiopathic pulmonary fibrosis O14746 (related)
H00022 Bladder cancer O14746 (marker)
P00533 (related)
P04626 (related)
P22607 (related)
P53355 (related)
H00024 Prostate cancer O14746 (marker)
H00577 Syndromic X-linked mental retardation with epilepsy or seizures O14936 (related)
H00894 FG syndrome (FGS) O14936 (related)
H00882 Cocoon syndrome O15111 (related)
H00136 Niemann-Pick disease type C (NPC) O15118 (related)
H00770 Congenital myasthenic syndrome O15146 (related)
H00865 Lethal congenital contractural syndrome (LCCS) O60331 (related)
P21860 (related)
H00012 Polycythemia vera O60674 (related)
O60674 (marker)
H00480 Non-syndromic X-linked mental retardation O75914 (related)
P51812 (related)
H00478 Prader-Willi and Angelman syndromes O76039 (related)
H00606 Early infantile epileptic encephalopathy O76039 (related)
P53779 (related)
H00881 Li-Fraumeni syndrome O96017 (related)
H00018 Gastric cancer O96020 (related)
P00533 (related)
P04626 (related)
P08581 (related)
P21802 (related)
P24864 (related)
H00055 Laryngeal cancer O96020 (related)
P00533 (related)
P00533 (marker)
P24385 (related)
P24385 (marker)
P24864 (related)
H00001 Acute lymphoblastic leukemia (ALL) (precursor B lymphoblastic leukemia) P00519 (related)
P00519 (marker)
Q03164 (related)
Q03164 (marker)
H00004 Chronic myeloid leukemia (CML) P00519 (related)
P00519 (marker)
H00016 Oral cancer P00533 (related)
P00533 (marker)
P24385 (related)
P24385 (marker)
H00017 Esophageal cancer P00533 (related)
P24385 (related)
H00028 Choriocarcinoma P00533 (related)
P04626 (related)
P07333 (related)
H00030 Cervical cancer P00533 (related)
P04626 (related)
P11802 (related)
H00042 Glioma P00533 (related)
P00533 (marker)
P09619 (related)
P11802 (related)
P16234 (related)
H00264 Charcot-Marie-Tooth disease (CMT) P02545 (related)
Q15046 (related)
H00294 Dilated cardiomyopathy (DCM) P02545 (related)
H00420 Familial partial lipodystrophy (FPL) P02545 (related)
P31751 (related)
H00563 Emery-Dreifuss muscular dystrophy P02545 (related)
H00590 Congenital muscular dystrophies (CMD/MDC) P02545 (related)
H00593 Limb-girdle muscular dystrophy (LGMD) P02545 (related)
H00601 Hutchinson-Gilford progeria syndrome P02545 (related)
H00663 Restrictive dermopathy P02545 (related)
H00665 Mandibuloacral dysplasia P02545 (related)
H01216 Left ventricular noncompaction (LVNC) P02545 (related)
H00019 Pancreatic cancer P04626 (related)
Q15831 (related)
H00026 Endometrial Cancer P04626 (related)
H00027 Ovarian cancer P04626 (related)
P31751 (related)
P42336 (related)
H00031 Breast cancer P04626 (related)
P04626 (marker)
P24385 (related)
H00046 Cholangiocarcinoma P04626 (related)
P08581 (related)
H00032 Thyroid cancer P04629 (related)
P07949 (related)
P07949 (marker)
P15056 (related)
H00043 Neuroblastoma P04629 (related)
P04629 (marker)
Q16288 (related)
Q16620 (related)
H00265 Hereditary sensory and autonomic neuropathy (HSAN) P04629 (related)
H00063 Spinocerebellar ataxia (SCA) P05129 (related)
Q8NI60 (related)
H00719 Leprechaunism P06213 (related)
H00942 Rabson-Mendenhall syndrome P06213 (related)
H01228 Insulin-resistant diabetes mellitus with acanthosis nigricans (IRAN) P06213 (related)
H01267 Familial hyperinsulinemic hypoglycemia (HHF) P06213 (related)
P35557 (related)
H00093 Combined immunodeficiencies (CIDs) P06239 (related)
P43403 (related)
H00822 Renal agenesis and Renal adysplasia P07949 (related)
H00910 Hirschsprung disease (HD) P07949 (related)
H00916 Congenital central hypoventilation syndrome (CCHS) P07949 (related)
H00015 Malignant pleural mesothelioma P08069 (related)
H00050 Synovial sarcoma P08069 (related)
H01274 Growth delay due to insulin-like growth factor I resistance P08069 (related)
H00021 Renal cell carcinoma P08581 (related)
H00014 Non-small cell lung cancer P08922 (related)
Q9UM73 (related)
H00058 Amyotrophic lateral sclerosis (ALS) P10636 (related)
H00077 Progressive supranuclear palsy (PSP) P10636 (related)
H00078 Frontotemporal lobar degeneration (FTLD) P10636 (related)
H00003 Acute myeloid leukemia (AML) P10721 (related)
P10721 (marker)
P36888 (related)
H00170 Piebaldism P10721 (related)
H00023 Testicular cancer P10721 (marker)
H00255 Hypogonadotropic hypogonadism P11362 (related)
H00443 Osteoglophonic dysplasia (OD) P11362 (related)
H00458 Craniosynostosis P11362 (related)
P21802 (related)
P22607 (related)
H00516 Isolated orofacial clefts P11362 (related)
H01207 Trigonocephaly P11362 (related)
H00038 Malignant melanoma P11802 (related)
P15056 (related)
H00523 Noonan syndrome and related disorders P15056 (related)
P36507 (related)
Q02750 (related)
H00457 Primary hypertrophic osteoarthropathy (PHO) P15428 (related)
H01246 Isolated congenital nail clubbing (ICNC) P15428 (related)
H00069 Glycogen storage diseases (GSD) P15735 (related)
P46019 (related)
P46020 (related)
Q93100 (related)
Q9UGJ0 (related)
H00642 Lacrimo-auriculo-dento-digital syndrome (LADD) P21802 (related)
P22607 (related)
H00408 Type I diabetes mellitus P21860 (related)
Q04759 (related)
H00010 Multiple myeloma P22607 (related)
P24385 (related)
P30281 (related)
H00505 FGFR3-related short limb skeletal dysplasias P22607 (related)
H00997 CATSHL syndrome P22607 (related)
H00006 Hairy-cell leukemia P24385 (related)
H00559 von Hippel-Lindau syndrome P24385 (related)
H00047 Gallbladder cancer P24385 (marker)
H01202 Cataract P29317 (related)
H00107 Other well-defined immunodeficiency syndromes P29597 (related)
Q08881 (related)
H00539 PTEN hamartoma tumor syndrome (PHTS) P31749 (related)
H00410 Maturity onset diabetes of the young (MODY) P35557 (related)
P51451 (related)
H00512 Permanent neonatal diabetes mellitus (PNDM) P35557 (related)
H00535 Lymphedemas P35916 (related)
H01023 Juvenile polyposis syndrome P36894 (related)
H01024 Hereditary mixed polyposis syndrome P36894 (related)
H00800 Loeys-Dietz syndrome (LDS) P36897 (related)
P37173 (related)
H00801 Familial thoracic aortic aneurysm and dissection (TAAD) P36897 (related)
P37173 (related)
Q15746 (related)
H00533 Hereditary hemorrhagic telangiectasia (HHT) P37023 (related)
H00020 Colorectal cancer P37173 (related)
H00005 Chronic lymphocytic leukemia (CLL) P43403 (marker)
H00574 Coffin-Lowry syndrome (CLS) P51812 (related)
H00091 T-B+Severe combined immunodeficiencies (SCIDs) P52333 (related)
H00531 Venous malformations Q02763 (related)
H00002 Acute lymphoblastic leukemia (ALL) (precursor T lymphoblastic leukemia) Q03164 (related)
H00430 Fibrodysplasia ossificans progressiva (FOP) Q04771 (related)
Q04771 (marker)
H00085 Agammaglobulinemias Q06187 (related)
H00254 Pituitary Dwarfism (PD) Q06187 (related)
H00568 Myotonic dystrophy (DM) Q09013 (related)
H00720 Long QT syndrome Q12809 (related)
H00725 Short QT syndrome Q12809 (related)
H00527 Retinitis pigmentosa (RP) Q12866 (related)
H00632 Heterotaxy Q13705 (related)
H01300 Primary pulmonary hypertension (PPH) Q13873 (related)
H00666 Peutz-Jeghers syndrome Q15831 (related)
H00787 Congenital stationary night blindness (CSNB) Q15835 (related)
H00455 Spinal muscular atrophy (SMA) Q16637 (related)
H00777 Spondylometaepiphyseal dysplasia, short limb-hand type Q16832 (related)
H00057 Parkinson's disease (PD) Q5S007 (related)
H00066 Lewy body dementia (LBD) Q5S007 (related)
H00605 Deafness, autosomal recessive Q8NEV4 (related)
H00999 Coenzyme Q10 deficiency Q8NI60 (related)
H00511 Short rib-polydactyly syndrome Q96PY6 (related)
H01210 Hypomagnesemia Q9BX84 (related)
H00096 Defects of toll-like receptor signaling Q9NWZ3 (related)
H00292 Hypertrophic cardiomyopathy (HCM) Q9UGJ0 (related)
H01154 Wolff-Parkinson-White (WPW) syndrome Q9UGJ0 (related)
H00972 Endocrine-cerebro-osteodysplasia syndrome Q9UPZ9 (related)
H01282 Spermatogenic failure Q9UQB9 (related)

Diseases related to CTD interactions

2 disease in interactions with metabolites

MESH or OMIM name KNApSAcK
metabolite
D001943 Breast Neoplasms C00024753
D004487 Edema C00018127