Organism name | Brucea sumatrana |
---|---|
Genus | Brucea |
Family | Simaroubaceae |
Kingdom | Plantae |
Linked NCBI taxonomy name | Brucea |
---|---|
Linked NCBI taxonomy ID | 43722 |
Linked level | genus |
Family in NCBI taxonomy | Simaroubaceae |
---|---|
ID | 23808 |
Kingdom (Superkingdom) in NCBI taxonomy | Viridiplantae |
---|---|
ID | 33090 |
Plant class | rosids |
---|---|
ID | 71275 |
KNApSAcK ID | name | ChEMBL link | CTD link |
# of proteins in
ChEMBL interaction / related OMIM / related KEGG DISEASE |
# of genes in
CTD interaction / related diseases |
KCF-S
cluster |
phytochemical
cluster |
figure |
---|---|---|---|---|---|---|---|---|
C00003702 |
Bruceine D
|
CHEMBL477693
|
C030412
|
No. 432 | No. 51 | |||
C00003704 |
Brusatol
|
CHEMBL450464
CHEMBL1702665 |
C020237
|
9 / 15 / 8 | 2 / 0 | No. 2130 | No. 51 |
accession | description | class description | KNApSAcK metabolite in interactions |
# of diseases
(OMIM / KEGG) |
---|---|---|---|---|
Q99700 | Ataxin-2 | Unclassified protein | C00003704 | 1 / 1 |
P49798 | Regulator of G-protein signaling 4 | Unclassified protein | C00003704 | 2 / 0 |
P37840 | Alpha-synuclein | Unclassified protein | C00003704 | 4 / 2 |
O75496 | Geminin | Unclassified protein | C00003704 | 0 / 0 |
P63092 | Guanine nucleotide-binding protein G(s) subunit alpha isoforms short | Other membrane protein | C00003704 | 7 / 3 |
P83916 | Chromobox protein homolog 1 | Unclassified protein | C00003704 | 0 / 0 |
Q16236 | Nuclear factor erythroid 2-related factor 2 | Unclassified protein | C00003704 | 0 / 0 |
P05412 | Transcription factor AP-1 | Transcription Factor | C00003704 | 0 / 0 |
Q06710 | Paired box protein Pax-8 | Unclassified protein | C00003704 | 1 / 2 |
gene | gene name | gene description | KNApSAcK metabolite in interactions |
---|---|---|---|
9817 | KEAP1, INrf2, KLHL19 | kelch-like ECH-associated protein 1 |
C00003704
|
4780 | NFE2L2, NRF2 | nuclear factor, erythroid 2-like 2 |
C00003704
|
OMIM | preferred title | UniProt |
---|---|---|
#219080 | Acth-independent macronodular adrenal hyperplasia; aimah |
P63092
|
#127750 | Dementia, lewy body; dlb |
P37840
|
#218700 | Hypothyroidism, congenital, nongoitrous, 2; chng2 |
Q06710
|
#174800 | Mccune-albright syndrome; mas |
P63092
|
#166350 | Osseous heteroplasia, progressive; poh |
P63092
|
#168601 | Parkinson disease 1, autosomal dominant; park1 |
P37840
|
#605543 | Parkinson disease 4, autosomal dominant; park4 |
P37840
|
#168600 | Parkinson disease, late-onset; pd |
P37840
|
#102200 | Pituitary adenoma, growth hormone-secreting |
P63092
|
#103580 | Pseudohypoparathyroidism, type ia; php1a |
P63092
|
#603233 | Pseudohypoparathyroidism, type ib; php1b |
P63092
|
#612462 | Pseudohypoparathyroidism, type ic; php1c |
P63092
|
#604906 | Schizophrenia 9; sczd9 |
P49798
|
#181500 | Schizophrenia; sczd |
P49798
|
#183090 | Spinocerebellar ataxia 2; sca2 |
Q99700
|
KEGG | name | UniProt |
---|---|---|
H00057 | Parkinson's disease (PD) |
P37840
(related)
|
H00066 | Lewy body dementia (LBD) |
P37840
(related)
|
H00244 | Pseudohypoparathyroidism |
P63092
(related)
|
H00441 | Progressive osseous heteroplasia (POH) |
P63092
(related)
|
H00501 | Fibrous dysplasia, polyostotic |
P63092
(related)
|
H00032 | Thyroid cancer |
Q06710
(related)
|
H00250 | Congenital nongoitrous hypothyroidism (CHNG) |
Q06710
(related)
|
H00063 | Spinocerebellar ataxia (SCA) |
Q99700
(related)
|