Species

KNApSAcK Entry

Organism name Quassia simarouba
Genus Quassia
Family Simaroubaceae
Kingdom Plantae

NCBI taxonomy

Entry

Linked NCBI taxonomy name Simarouba amara
Linked NCBI taxonomy ID 101569
Linked level species

Family

Family in NCBI taxonomy Simaroubaceae
ID 23808

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy Viridiplantae
ID 33090

Plant class

Plant class rosids
ID 71275

Metabolite list (3)

KNApSAcK ID name ChEMBL link CTD link # of proteins in
ChEMBL interaction
/ related OMIM
/ related KEGG DISEASE
# of genes in
CTD interaction
/ related diseases
KCF-S
cluster
phytochemical
cluster
figure
C00003712 External link 512 Glaucarubolone
CHEMBL510560
CHEMBL523681
C024967
No. 432 No. 51
C00003711 External link 512 Glaucarubinone
CHEMBL458347
CHEMBL1728992
C015235
10 / 7 / 8 No. 704 No. 51
C00003710 External link 512 Glaucarubin
CHEMBL602805
CHEMBL1997250
CHEMBL2106871
D005900
No. 704 No. 51

Human Protein / Gene in interactions

10 ChEMBL Protein in interactions

accession description class description KNApSAcK metabolite in interactions # of diseases
(OMIM / KEGG)
Q99700 Ataxin-2 Unclassified protein C00003711 1 / 1
P84022 Mothers against decapentaplegic homolog 3 Unclassified protein C00003711 2 / 0
O75496 Geminin Unclassified protein C00003711 0 / 0
P40763 Signal transducer and activator of transcription 3 Transcription Factor C00003711 1 / 2
O15111 Inhibitor of nuclear factor kappa-B kinase subunit alpha Other serine/threonine protein kinase C00003711 1 / 1
Q16236 Nuclear factor erythroid 2-related factor 2 Unclassified protein C00003711 0 / 0
P05412 Transcription factor AP-1 Transcription Factor C00003711 0 / 0
O75874 Isocitrate dehydrogenase [NADP] cytoplasmic Enzyme C00003711 1 / 0
P01215 Glycoprotein hormones alpha chain Unclassified protein C00003711 0 / 3
Q06710 Paired box protein Pax-8 Unclassified protein C00003711 1 / 2

Related Diseases

Diseases related to proteins in ChEMBL interactions

OMIM (7)

OMIM preferred title UniProt
#613630 Cocoon syndrome O15111
#114500 Colorectal cancer; crc P84022
#137800 Glioma susceptibility 1; glm1 O75874
#147060 Hyper-ige recurrent infection syndrome, autosomal dominant P40763
#218700 Hypothyroidism, congenital, nongoitrous, 2; chng2 Q06710
#613795 Loeys-dietz syndrome, type 3; lds3 P84022
#183090 Spinocerebellar ataxia 2; sca2 Q99700

KEGG DISEASE (8)

KEGG name UniProt
H00882 Cocoon syndrome O15111 (related)
H00081 Hashimoto's thyroiditis P01215 (marker)
H00082 Graves' disease P01215 (marker)
H00250 Congenital nongoitrous hypothyroidism (CHNG) P01215 (marker)
Q06710 (related)
H00016 Oral cancer P40763 (related)
H00107 Other well-defined immunodeficiency syndromes P40763 (related)
H00032 Thyroid cancer Q06710 (related)
H00063 Spinocerebellar ataxia (SCA) Q99700 (related)