Species

KNApSAcK Entry

Organism name Helianthus annuus L.
Genus Helianthus
Family Asteraceae
Kingdom Plantae

NCBI taxonomy

Entry

Linked NCBI taxonomy name Helianthus annuus
Linked NCBI taxonomy ID 4232
Linked level species

Family

Family in NCBI taxonomy Asteraceae
ID 4210

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy Viridiplantae
ID 33090

Plant class

Plant class asterids
ID 71274

Natural Activity

List (11)

Species Activity
Helianthus annuus L. Antiinflammatory
Helianthus annuus L. Antipyretic
Helianthus annuus L. Aperitif
Helianthus annuus L. Astringent
Helianthus annuus L. Deobstruent
Helianthus annuus L. Diuretic
Helianthus annuus L. Emollient
Helianthus annuus L. Expectorant
Helianthus annuus L. Stimulant
Helianthus annuus L. Vermifuge
Helianthus annuus L. Vulnerary

Metabolite list (3)

KNApSAcK ID name ChEMBL link CTD link # of proteins in
ChEMBL interaction
/ related OMIM
/ related KEGG DISEASE
# of genes in
CTD interaction
/ related diseases
KCF-S
cluster
phytochemical
cluster
figure
C00003776 External link 512 Lutein
/ (all-E)-Lutein
/ all-trans-(+)-Xanthophyll
/ (3R,3'R,6'R)-beta,epsilon-Carotene-3,3'-diol
CHEMBL173929
CHEMBL172477
CHEMBL1559643
CHEMBL1979448
D014975
4 / 2 / 3 7 / 2 No. 26 No. 59
C00037923 External link 512 Trachyloban-19-oic acid
/ (-)-Trachyloban-19-oic acid
CHEMBL511801
CHEMBL463698
CHEMBL1164460
C039978
1 / 0 / 0 No. 203 No. 41
C00037865 External link 512 Sundiversifolide
/ 4,15-Dinor-3-hydroxy-1(5)-xanthene-12,8-olide
No. 2121

Human Protein / Gene in interactions

5 ChEMBL Protein in interactions

accession description class description KNApSAcK metabolite in interactions # of diseases
(OMIM / KEGG)
P11473 Vitamin D3 receptor NR1I1 C00003776 2 / 3
O75496 Geminin Unclassified protein C00003776 0 / 0
O94782 Ubiquitin carboxyl-terminal hydrolase 1 Enzyme C00003776 0 / 0
Q07817 Bcl-2-like protein 1 Other cytosolic protein C00037923 0 / 0
Q96KQ7 Histone-lysine N-methyltransferase EHMT2 Enzyme C00003776 0 / 0

7 Gene in CTD interactions

gene gene name gene description KNApSAcK metabolite in interactions
581 BAX, BCL2L4 BCL2-associated X protein C00003776
596 BCL2, Bcl-2, PPP1R50 B-cell CLL/lymphoma 2 C00003776
598 BCL2L1, BCL-XL/S, BCL2L, BCLX, BCLXL, BCLXS, Bcl-X, PPP1R52, bcl-xL, bcl-xS BCL2-like 1 C00003776
847 CAT catalase (EC:1.11.1.6) C00003776
595 CCND1, BCL1, D11S287E, PRAD1, U21B31 cyclin D1 C00003776
5743 PTGS2, COX-2, COX2, GRIPGHS, PGG/HS, PGHS-2, PHS-2, hCox-2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) (EC:1.14.99.1) C00003776
5970 RELA, NFKB3, p65 v-rel avian reticuloendotheliosis viral oncogene homolog A C00003776

Related Diseases

Diseases related to proteins in ChEMBL interactions

OMIM (2)

OMIM preferred title UniProt
#607948 Mycobacterium tuberculosis, susceptibility to P11473
#277440 Vitamin d-dependent rickets, type 2a; vddr2a P11473

KEGG DISEASE (3)

KEGG name UniProt
H00342 Tuberculosis P11473 (related)
H00784 Localized autosomal recessive hypotrichosis P11473 (related)
H01143 Vitamin D-dependent rickets P11473 (related)

Diseases related to CTD interactions

2 disease in interactions with metabolites

MESH or OMIM name KNApSAcK
metabolite
D007939 Leukemia L1210 C00003776
D014605 Uveitis C00003776