Heracleum granatense

• Index
• Plant Species
• Metabolite list (13)
• Human Protein
  / Gene in interactions
• Related Diseases

Species

KNApSAcK Entry

Organism name	Heracleum granatense
Genus	Heracleum
Family	Apiaceae
Kingdom	Plantae

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NCBI taxonomy

Entry

Linked NCBI taxonomy name	Heracleum
Linked NCBI taxonomy ID	40917
Linked level	genus

Family

Family in NCBI taxonomy	Apiaceae
ID	4037

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy	Viridiplantae
ID	33090

Plant class

Plant class	asterids
ID	71274

Metabolite list (13)

KNApSAcK ID	name	ChEMBL link	CTD link	# of proteins in ChEMBL interaction / related OMIM / related KEGG DISEASE	# of genes in CTD interaction / related diseases	KCF-S cluster	phytochemical cluster	figure
C00003672	Sitosterol / beta-sitosterl / (-)-beta-Sitosterol / Stigmast-5-en-3beta-ol	CHEMBL221542 CHEMBL1398443 CHEMBL1875388		17 / 19 / 12		No. 53	No. 11
C00029633	Ursolic acid / Acetylursolic acid	CHEMBL55086 CHEMBL410525		4 / 2 / 2		No. 177
C00019308	Doursterol / Daucosterin / 3-O-beta-D-Glucopyranosyl sitosterol / beta-Sitosterol 3-O-beta-D-glucopyranoside	CHEMBL197711 CHEMBL506678 CHEMBL2304043	C011015	5 / 4 / 2	0 / 3	No. 520
C00002453	Byakangelicin / (+)-Byakangelicin	CHEMBL508648	C434685	5 / 2 / 0		No. 579	No. 25
C00037262	Heraclenol	CHEMBL1173444	C087805	3 / 0 / 0		No. 579	No. 25
C00000583	Isopimpinellin	CHEMBL140796	C015304	9 / 3 / 4	2 / 0	No. 606	No. 25
C00030987	Phellopterin	CHEMBL452751	C104601	7 / 18 / 10		No. 606	No. 25
C00002477	Imperatorin	CHEMBL453805	C031534	18 / 7 / 6	1 / 1	No. 606	No. 25
C00002499	Scopoletin	CHEMBL71851	D012603	48 / 37 / 34	9 / 0	No. 864	No. 25
C00002503	Umbelliferon / Umbelliferone / 7-Hydroxycoumarin	CHEMBL51628	C031477	39 / 33 / 32	9 / 0	No. 1030	No. 25
C00000575	Bergaptan	CHEMBL24171	C022909	22 / 22 / 17	0 / 3	No. 1282	No. 25
C00000576	Xanthotoxin	CHEMBL416	D008730	104 / 55 / 45	22 / 18	No. 1282	No. 25
C00037321	Isobergapten	CHEMBL141690		8 / 5 / 4		No. 1282	No. 25

Human Protein / Gene in interactions

174 ChEMBL Protein in interactions

accession	description	class description	KNApSAcK metabolite in interactions	# of diseases (OMIM / KEGG)
P56817	Beta-secretase 1	A1A	C00000575 C00000576 C00000583 C00002453 C00002477 C00002503 C00030987 C00037262	0 / 0
P08684	Cytochrome P450 3A4	Cytochrome P450 3A4	C00000575 C00000576 C00000583 C00002477 C00002499 C00003672 C00037321	0 / 1
B2RXH2	Lysine-specific demethylase 4E	Enzyme	C00000575 C00000583 C00002453 C00002499 C00002503 C00037321	0 / 0
P00352	Retinal dehydrogenase 1	Enzyme	C00000575 C00002477 C00002499 C00002503 C00037321	0 / 0
P83916	Chromobox protein homolog 1	Unclassified protein	C00000575 C00000576 C00002453 C00002477 C00002503	0 / 0
P10635	Cytochrome P450 2D6	Cytochrome P450 2D6	C00000575 C00000576 C00002499 C00003672	1 / 0
P06746	DNA polymerase beta	Enzyme	C00000583 C00003672 C00019308 C00029633	0 / 0
P33261	Cytochrome P450 2C19	Cytochrome P450 2C19	C00000575 C00000576 C00002499 C00003672	1 / 1
P63092	Guanine nucleotide-binding protein G(s) subunit alpha isoforms short	Other membrane protein	C00000575 C00000576 C00002499 C00030987	7 / 3
O75496	Geminin	Unclassified protein	C00002499 C00002503 C00037262 C00037321	0 / 0
Q96KQ7	Histone-lysine N-methyltransferase EHMT2	Enzyme	C00002477 C00002499 C00037262 C00037321	0 / 0
P11712	Cytochrome P450 2C9	Cytochrome P450 2C9	C00000575 C00000576 C00002499 C00003672	0 / 1
Q13148	TAR DNA-binding protein 43	Unclassified protein	C00000576 C00000583 C00002477 C00030987	1 / 1
P35354	Prostaglandin G/H synthase 2	Oxidoreductase	C00000576 C00002499 C00002503	0 / 3
Q92830	Histone acetyltransferase KAT2A	Enzyme	C00000583 C00002499 C00002503	0 / 0
P05177	Cytochrome P450 1A2	Cytochrome P450 1A2	C00000576 C00002499 C00003672	0 / 0
O75874	Isocitrate dehydrogenase [NADP] cytoplasmic	Enzyme	C00002453 C00002477 C00037321	1 / 0
Q99714	3-hydroxyacyl-CoA dehydrogenase type-2	Enzyme	C00000575 C00002499 C00002503	3 / 3
P15428	15-hydroxyprostaglandin dehydrogenase [NAD(+)]	Enzyme	C00000583 C00002499 C00002503	2 / 2
P27695	DNA-(apurinic or apyrimidinic site) lyase	Enzyme	C00000583 C00002477 C00029633	0 / 0
P00918	Carbonic anhydrase 2	Lyase	C00000576 C00002499 C00002503	1 / 2
P16473	Thyrotropin receptor	Glycohormone receptor	C00000575 C00000576 C00003672	3 / 2
P10253	Lysosomal alpha-glucosidase	Hydrolase	C00002477 C00002499 C00002503	1 / 1
P18031	Tyrosine-protein phosphatase non-receptor type 1	Tyr	C00002499 C00003672 C00019308	0 / 0
P29466	Caspase-1	C14	C00000576 C00002499 C00002503	0 / 0
P22303	Acetylcholinesterase	Hydrolase	C00000576 C00002499 C00002503	1 / 0
Q16236	Nuclear factor erythroid 2-related factor 2	Unclassified protein	C00000575 C00000583	0 / 0
P04406	Glyceraldehyde-3-phosphate dehydrogenase	Enzyme	C00002499 C00002503	0 / 0
P10636	Microtubule-associated protein tau	Unclassified protein	C00030987 C00037321	4 / 3
P22309	UDP-glucuronosyltransferase 1-1	Enzyme	C00002499 C00002503	5 / 1
P10275	Androgen receptor	NR3C4	C00000575 C00000576	3 / 4
P20813	Cytochrome P450 2B6	Cytochrome P450 2B6	C00000575 C00000576	1 / 0
P80365	Corticosteroid 11-beta-dehydrogenase isozyme 2	Enzyme	C00002503 C00003672	1 / 1
P55210	Caspase-7	C14	C00002499 C00002503	0 / 0
P08047	Transcription factor Sp1	Unclassified protein	C00003672 C00019308	0 / 0
Q00796	Sorbitol dehydrogenase	Enzyme	C00002499 C00002503	0 / 0
P04062	Glucosylceramidase	Enzyme	C00002499 C00002503	6 / 4
P47989	Xanthine dehydrogenase/oxidase	Oxidoreductase	C00002499 C00002503	1 / 1
P22310	UDP-glucuronosyltransferase 1-4	Enzyme	C00002499 C00002503	3 / 0
P46063	ATP-dependent DNA helicase Q1	Enzyme	C00002499 C00029633	0 / 0
P03372	Estrogen receptor	NR3A1	C00000576 C00003672	1 / 1
Q9Y4X1	UDP-glucuronosyltransferase 2A1	Enzyme	C00002499 C00002503	0 / 0
Q9HAW9	UDP-glucuronosyltransferase 1-8	Enzyme	C00002499 C00002503	0 / 0
Q09470	Potassium voltage-gated channel subfamily A member 1	KCNA, Kv1.x (Shaker)	C00000575 C00000576	1 / 1
Q9NUW8	Tyrosyl-DNA phosphodiesterase 1	Enzyme	C00002503 C00003672	1 / 1
Q16790	Carbonic anhydrase 9	Lyase	C00002499 C00002503	0 / 1
O00255	Menin	Unclassified protein	C00002499 C00002503	2 / 5
P06280	Alpha-galactosidase A	Enzyme	C00002499 C00002503	1 / 1
P14679	Tyrosinase	Oxidoreductase	C00002503 C00003672	4 / 2
P08183	Multidrug resistance protein 1	drug	C00000575 C00003672	1 / 0
P00734	Prothrombin	S1A	C00003672 C00019308	4 / 2
O94782	Ubiquitin carboxyl-terminal hydrolase 1	Enzyme	C00002477 C00037321	0 / 0
Q9HAW8	UDP-glucuronosyltransferase 1-10	Enzyme	C00002499 C00002503	0 / 0
P43220	Glucagon-like peptide 1 receptor	Glucagon-like peptide receptor	C00000576 C00002477	0 / 0
P49841	Glycogen synthase kinase-3 beta	Gsk	C00003672 C00019308	0 / 0
Q9NR56	Muscleblind-like protein 1	Unclassified protein	C00002453 C00030987	1 / 0
P00915	Carbonic anhydrase 1	Lyase	C00002499 C00002503	0 / 0
P11473	Vitamin D3 receptor	NR1I1	C00000576 C00002477	2 / 3
P15121	Aldose reductase	Enzyme	C00002499 C00002503	0 / 0
P54855	UDP-glucuronosyltransferase 2B15	Enzyme	C00002499 C00002503	0 / 0
Q99700	Ataxin-2	Unclassified protein	C00002499 C00002503	1 / 1
Q03164	Histone-lysine N-methyltransferase 2A	Enzyme	C00002499 C00002503	1 / 2
P11509	Cytochrome P450 2A6	Cytochrome P450 2A6	C00000575 C00000576	0 / 0
O43570	Carbonic anhydrase 12	Lyase	C00002499 C00002503	1 / 2
P49798	Regulator of G-protein signaling 4	Unclassified protein	C00002477 C00003672	2 / 0
O76074	cGMP-specific 3',5'-cyclic phosphodiesterase	PDE_5A	C00000576	0 / 0
P50052	Type-2 angiotensin II receptor	Angiotensin receptor	C00000576	1 / 1
P17948	Vascular endothelial growth factor receptor 1	Vegfr	C00000576	0 / 0
P41968	Melanocortin receptor 3	Melanocortin receptor	C00000576	1 / 0
P25929	Neuropeptide Y receptor type 1	Neuropeptide Y receptor	C00000576	0 / 0
P28845	Corticosteroid 11-beta-dehydrogenase isozyme 1	Enzyme	C00002503	1 / 1
P29274	Adenosine receptor A2a	Adenosine receptor	C00000576	0 / 0
Q9Y271	Cysteinyl leukotriene receptor 1	Leukotriene receptor	C00000576	0 / 0
Q16665	Hypoxia-inducible factor 1-alpha	Transcription Factor	C00002499	0 / 0
P39748	Flap endonuclease 1	Enzyme	C00002503	0 / 0
P41145	Kappa-type opioid receptor	Opioid receptor	C00000576	0 / 0
P11413	Glucose-6-phosphate 1-dehydrogenase	Enzyme	C00030987	1 / 2
P37288	Vasopressin V1a receptor	Vasopressin and oxytocin receptor	C00000576	0 / 0
O60656	UDP-glucuronosyltransferase 1-9	Enzyme	C00002499	0 / 0
P23219	Prostaglandin G/H synthase 1	Oxidoreductase	C00000576	0 / 0
P04035	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Oxidoreductase	C00000576	0 / 0
P08913	Alpha-2A adrenergic receptor	Adrenergic receptor	C00000576	0 / 0
P18405	3-oxo-5-alpha-steroid 4-dehydrogenase 1	Oxidoreductase	C00002503	0 / 0
P21917	D(4) dopamine receptor	Dopamine receptor	C00000576	0 / 0
P30988	Calcitonin receptor	Calcitonin receptor	C00000576	0 / 0
P35462	D(3) dopamine receptor	Dopamine receptor	C00000576	1 / 0
P41143	Delta-type opioid receptor	Opioid receptor	C00000576	0 / 0
Q92731	Estrogen receptor beta	NR3A2	C00000576	0 / 1
P41595	5-hydroxytryptamine receptor 2B	Serotonin receptor	C00000576	0 / 0
P14416	D(2) dopamine receptor	Dopamine receptor	C00000576	2 / 0
P25101	Endothelin-1 receptor	Endothelin receptor	C00000576	0 / 0
P30411	B2 bradykinin receptor	Bradykinin receptor	C00000576	0 / 0
P32245	Melanocortin receptor 4	Melanocortin receptor	C00000576	1 / 0
P00533	Epidermal growth factor receptor	TK tyrosine-protein kinase EGFR subfamily	C00000576	1 / 8
P23443	Ribosomal protein S6 kinase beta-1	p70	C00000576	0 / 0
P32238	Cholecystokinin receptor type A	Cholecystokinin receptor	C00000576	0 / 0
P08311	Cathepsin G	S1A	C00000576	0 / 0
Q99720	Sigma non-opioid intracellular receptor 1	Membrane receptor	C00000576	1 / 0
P09917	Arachidonate 5-lipoxygenase	Oxidoreductase	C00002499	0 / 0
P03956	Interstitial collagenase	M10A	C00000576	0 / 1
P32241	Vasoactive intestinal polypeptide receptor 1	Vasoactive intestinal peptide receptor	C00000576	0 / 0
Q08209	Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform	Ser_Thr	C00000576	0 / 0
Q04206	Transcription factor p65	Transcription Factor	C00002499	0 / 0
O94956	Solute carrier organic anion transporter family member 2B1	Unclassified protein	C00000576	0 / 0
Q9NPD5	Solute carrier organic anion transporter family member 1B3	Electrochemical transporter	C00000576	1 / 0
P06241	Tyrosine-protein kinase Fyn	Src	C00000576	0 / 0
P25024	C-X-C chemokine receptor type 1	CXC chemokine receptor	C00000576	0 / 0
P04150	Glucocorticoid receptor	NR3C1	C00000576	0 / 1
P08172	Muscarinic acetylcholine receptor M2	Acetylcholine receptor	C00000576	2 / 0
P11229	Muscarinic acetylcholine receptor M1	Acetylcholine receptor	C00000576	0 / 0
P11511	Cytochrome P450 19A1	Cytochrome P450 19A1	C00029633	2 / 2
P51452	Dual specificity protein phosphatase 3	Ser_Thr_Tyr	C00002477	0 / 0
P21554	Cannabinoid receptor 1	Cannabinoid receptor	C00000576	0 / 0
P31645	Sodium-dependent serotonin transporter	Serotonin	C00000576	2 / 0
P04626	Receptor tyrosine-protein kinase erbB-2	TK tyrosine-protein kinase EGFR subfamily	C00000576	5 / 9
P20309	Muscarinic acetylcholine receptor M3	Acetylcholine receptor	C00000576	1 / 0
P21452	Substance-K receptor	Neurokinin receptor	C00000576	0 / 0
P51679	C-C chemokine receptor type 4	CC chemokine receptor	C00000576	0 / 0
P51681	C-C chemokine receptor type 5	CC chemokine receptor	C00000576	3 / 0
P50406	5-hydroxytryptamine receptor 6	Serotonin receptor	C00000576	0 / 0
P34969	5-hydroxytryptamine receptor 7	Serotonin receptor	C00002477	0 / 0
P35236	Tyrosine-protein phosphatase non-receptor type 7	Tyr	C00002477	0 / 0
P41597	C-C chemokine receptor type 2	CC chemokine receptor	C00000576	1 / 0
P28482	Mitogen-activated protein kinase 1	Erk	C00000576	0 / 0
P08575	Receptor-type tyrosine-protein phosphatase C	Enzyme	C00000576	2 / 1
Q9Y6L6	Solute carrier organic anion transporter family member 1B1	Electrochemical transporter	C00000576	1 / 0
P13945	Beta-3 adrenergic receptor	Adrenergic receptor	C00000576	0 / 0
P18825	Alpha-2C adrenergic receptor	Adrenergic receptor	C00000576	0 / 0
P08912	Muscarinic acetylcholine receptor M5	Acetylcholine receptor	C00000576	0 / 0
Q01959	Sodium-dependent dopamine transporter	Dopamine	C00000576	1 / 0
P48547	Potassium voltage-gated channel subfamily C member 1	K	C00000575	0 / 0
P35367	Histamine H1 receptor	Histamine receptor	C00000576	0 / 0
P25021	Histamine H2 receptor	Histamine receptor	C00000576	0 / 0
P16389	Potassium voltage-gated channel subfamily A member 2	KCNA, Kv1.x (Shaker)	C00000575	0 / 0
P21397	Amine oxidase [flavin-containing] A	Oxidoreductase	C00000576	1 / 1
P08588	Beta-1 adrenergic receptor	Adrenergic receptor	C00000576	1 / 0
P07550	Beta-2 adrenergic receptor	Adrenergic receptor	C00000576	0 / 1
P28223	5-hydroxytryptamine receptor 2A	Serotonin receptor	C00000576	0 / 0
P28335	5-hydroxytryptamine receptor 2C	Serotonin receptor	C00000576	0 / 0
P35372	Mu-type opioid receptor	Opioid receptor	C00000576	0 / 0
P08173	Muscarinic acetylcholine receptor M4	Acetylcholine receptor	C00000576	0 / 0
P25103	Substance-P receptor	Neurokinin receptor	C00000576	0 / 0
P25105	Platelet-activating factor receptor	PAF receptor	C00000576	0 / 0
P33032	Melanocortin receptor 5	Melanocortin receptor	C00000576	0 / 0
P37840	Alpha-synuclein	Unclassified protein	C00030987	4 / 2
P55789	FAD-linked sulfhydryl oxidase ALR	Enzyme	C00002499	1 / 0
O75795	UDP-glucuronosyltransferase 2B17	Enzyme	C00002499	1 / 0
P17658	Potassium voltage-gated channel subfamily A member 6	K	C00000575	0 / 0
P05181	Cytochrome P450 2E1	Cytochrome P450 2E1	C00000576	0 / 0
O75164	Lysine-specific demethylase 4A	Enzyme	C00002477	0 / 0
Q8N1Q1	Carbonic anhydrase 13	Lyase	C00002499	0 / 0
Q13526	Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1	Enzyme	C00002499	0 / 0
P14780	Matrix metalloproteinase-9	M10A	C00000576	2 / 2
P27361	Mitogen-activated protein kinase 3	Erk	C00000576	0 / 0
P17252	Protein kinase C alpha type	Alpha	C00000576	0 / 0
P23975	Sodium-dependent noradrenaline transporter	Norepinephrine	C00000576	1 / 1
P25100	Alpha-1D adrenergic receptor	Adrenergic receptor	C00000576	0 / 0
P30542	Adenosine receptor A1	Adenosine receptor	C00000576	0 / 0
P18089	Alpha-2B adrenergic receptor	Adrenergic receptor	C00000576	0 / 0
P24557	Thromboxane-A synthase	Cytochrome P450 5A1	C00000576	1 / 1
P06239	Tyrosine-protein kinase Lck	Src	C00000576	0 / 1
P22460	Potassium voltage-gated channel subfamily A member 5	KCNA, Kv1.x (Shaker)	C00000575	1 / 1
P25025	C-X-C chemokine receptor type 2	CXC chemokine receptor	C00000576	0 / 0
P43166	Carbonic anhydrase 7	Lyase	C00002499	0 / 0
P22001	Potassium voltage-gated channel subfamily A member 3	KCNA, Kv1.x (Shaker)	C00000575	0 / 0
P49146	Neuropeptide Y receptor type 2	Neuropeptide Y receptor	C00000576	0 / 0
O00167	Eyes absent homolog 2	Enzyme	C00002477	0 / 0
P21728	D(1A) dopamine receptor	Dopamine receptor	C00000576	0 / 0
Q16539	Mitogen-activated protein kinase 14	p38	C00000576	0 / 0
P33765	Adenosine receptor A3	Adenosine receptor	C00000576	0 / 0
P08246	Neutrophil elastase	S1A	C00000576	2 / 1
Q12809	Potassium voltage-gated channel subfamily H member 2	KCNH, Kv10-12.x (Ether-a-go-go)	C00000576	2 / 2
O94925	Glutaminase kidney isoform, mitochondrial	Enzyme	C00002503	0 / 0
P51449	Nuclear receptor ROR-gamma	Nuclear hormone receptor subfamily 1 group F member 3	C00000576	0 / 0

36 Gene in CTD interactions

gene	gene name	gene description	KNApSAcK metabolite in interactions
1545	CYP1B1, CP1B, CYPIB1, GLC3A, P4501B1	cytochrome P450, family 1, subfamily B, polypeptide 1 (EC:1.14.14.1)	C00000583 C00002477
8856	NR1I2, BXR, ONR1, PAR, PAR1, PAR2, PARq, PRR, PXR, SAR, SXR	nuclear receptor subfamily 1, group I, member 2	C00000576 C00000583
7366	UGT2B15, HLUG4, UDPGT_2B8, UDPGT2B15, UDPGTH3, UGT2B8	UDP glucuronosyltransferase 2 family, polypeptide B15 (EC:2.4.1.17)	C00002499 C00002503
54600	UGT1A9, HLUGP4, LUGP4, UDPGT, UDPGT_1-9, UGT-1I, UGT1-09, UGT1-9, UGT1.9, UGT1AI, UGT1I	UDP glucuronosyltransferase 1 family, polypeptide A9 (EC:2.4.1.17)	C00002499 C00002503
581	BAX, BCL2L4	BCL2-associated X protein	C00000576 C00002503
596	BCL2, Bcl-2, PPP1R50	B-cell CLL/lymphoma 2	C00000576 C00002503
1548	CYP2A6, CPA6, CYP2A, CYP2A3, CYPIIA6, P450C2A, P450PB	cytochrome P450, family 2, subfamily A, polypeptide 6 (EC:1.14.14.1)	C00000576 C00002503
1543	CYP1A1, AHH, AHRR, CP11, CYP1, P1-450, P450-C, P450DX	cytochrome P450, family 1, subfamily A, polypeptide 1 (EC:1.14.14.1)	C00000576
6817	SULT1A1, HAST1/HAST2, P-PST, PST, ST1A1, ST1A3, STP, STP1, TSPST1	sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1 (EC:2.8.2.1)	C00002503
8574	AKR7A2, AFAR, AFAR1, AFB1-AR1, AKR7	aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase) (EC:1.1.1.n11)	C00002503
8644	AKR1C3, DD3, DDX, HA1753, HAKRB, HAKRe, HSD17B5, PGFS, hluPGFS	aldo-keto reductase family 1, member C3 (EC:1.3.1.20 1.1.1.188 1.1.1.239 1.1.1.64 1.1.1.112 1.1.1.357)	C00002503
8553	BHLHE40, BHLHB2, DEC1, HLHB2, SHARP-2, STRA13, Stra14	basic helix-loop-helix family, member e40	C00000576
332	BIRC5, API4, EPR-1	baculoviral IAP repeat containing 5	C00000576
836	CASP3, CPP32, CPP32B, SCA-1	caspase 3, apoptosis-related cysteine peptidase (EC:3.4.22.56)	C00000576
841	CASP8, ALPS2B, CAP4, Casp-8, FLICE, MACH, MCH5	caspase 8, apoptosis-related cysteine peptidase (EC:3.4.22.61)	C00000576
842	CASP9, APAF-3, APAF3, ICE-LAP6, MCH6, PPP1R56	caspase 9, apoptosis-related cysteine peptidase (EC:3.4.22.62)	C00000576
1027	CDKN1B, CDKN4, KIP1, MEN1B, MEN4, P27KIP1	cyclin-dependent kinase inhibitor 1B (p27, Kip1)	C00000576
8824	CES2, CE-2, CES2A1, PCE-2, iCE	carboxylesterase 2 (EC:3.1.1.1 3.1.1.84 3.1.1.56)	C00000576
595	CCND1, BCL1, D11S287E, PRAD1, U21B31	cyclin D1	C00002503
1544	CYP1A2, CP12, P3-450, P450(PA)	cytochrome P450, family 1, subfamily A, polypeptide 2 (EC:1.14.14.1)	C00000576
1553	CYP2A13, CPAD, CYP2A, CYPIIA13	cytochrome P450, family 2, subfamily A, polypeptide 13 (EC:1.14.14.1)	C00000576
1559	CYP2C9, CPC9, CYP2C, CYP2C10, CYPIIC9, P450IIC9	cytochrome P450, family 2, subfamily C, polypeptide 9 (EC:1.14.13.48 1.14.13.49 1.14.13.80)	C00000576
1565	CYP2D6, CPD6, CYP2D, CYP2D7AP, CYP2D7BP, CYP2D7P2, CYP2D8P2, CYP2DL1, CYPIID6, P450-DB1, P450C2D, P450DB1	cytochrome P450, family 2, subfamily D, polypeptide 6 (EC:1.14.14.1)	C00000576
1576	CYP3A4, CP33, CP34, CYP3A, CYP3A3, CYPIIIA3, CYPIIIA4, HLP, NF-25, P450C3, P450PCN1	cytochrome P450, family 3, subfamily A, polypeptide 4 (EC:1.14.13.67 1.14.13.97 1.14.13.32 1.14.13.157)	C00000576
3034	HAL, HIS, HSTD	histidine ammonia-lyase (EC:4.3.1.3)	C00000576
3355109			C00000576
5925	RB1, OSRC, RB, p105-Rb, pRb, pp110	retinoblastoma 1	C00000576
7124	TNF, DIF, TNF-alpha, TNFA, TNFSF2	tumor necrosis factor	C00000576
7157	TP53, BCC7, LFS1, P53, TRP53	tumor protein p53	C00000576
54658	UGT1A1, BILIQTL1, GNT1, HUG-BR1, UDPGT, UDPGT_1-1, UGT1, UGT1A	UDP glucuronosyltransferase 1 family, polypeptide A1 (EC:2.4.1.17)	C00002499
54575	UGT1A10, UDPGT, UGT-1J, UGT1-10, UGT1.10, UGT1J	UDP glucuronosyltransferase 1 family, polypeptide A10 (EC:2.4.1.17)	C00002499
54659	UGT1A3, UDPGT, UDPGT_1-3, UGT-1C, UGT1-03, UGT1.3, UGT1C	UDP glucuronosyltransferase 1 family, polypeptide A3 (EC:2.4.1.17)	C00002499
54578	UGT1A6, GNT1, HLUGP, HLUGP1, UDPGT, UDPGT_1-6, UGT1, UGT1A6S, UGT1F	UDP glucuronosyltransferase 1 family, polypeptide A6 (EC:2.4.1.17)	C00002499
54577	UGT1A7, UDPGT, UDPGT_1-7, UGT-1G, UGT1-07, UGT1.7, UGT1G	UDP glucuronosyltransferase 1 family, polypeptide A7 (EC:2.4.1.17)	C00002499
54576	UGT1A8, UDPGT, UDPGT_1-8, UGT-1H, UGT1-08, UGT1.8, UGT1A8S, UGT1H	UDP glucuronosyltransferase 1 family, polypeptide A8 (EC:2.4.1.17)	C00002499
7508	XPC, RAD4, XP3, XPCC	xeroderma pigmentosum, complementation group C	C00002499

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Diseases related to proteins in ChEMBL interactions

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