Organism name | Petroselinum spp. |
---|---|
Genus | Petroselinum |
Family | Apiaceae |
Kingdom | Plantae |
Linked NCBI taxonomy name | Petroselinum |
---|---|
Linked NCBI taxonomy ID | 4042 |
Linked level | genus |
Family in NCBI taxonomy | Apiaceae |
---|---|
ID | 4037 |
Kingdom (Superkingdom) in NCBI taxonomy | Viridiplantae |
---|---|
ID | 33090 |
Plant class | asterids |
---|---|
ID | 71274 |
KNApSAcK ID | name | ChEMBL link | CTD link |
# of proteins in
ChEMBL interaction / related OMIM / related KEGG DISEASE |
# of genes in
CTD interaction / related diseases |
KCF-S
cluster |
phytochemical
cluster |
figure |
---|---|---|---|---|---|---|---|---|
C00000575 |
Bergaptan
|
CHEMBL24171
|
C022909
|
22 / 22 / 17 | 0 / 3 | No. 1282 | No. 25 | |
C00002656 |
Hydroquinone
/ 1,4-Benzenediol |
CHEMBL537
|
C031927
|
55 / 48 / 51 | 156 / 14 | No. 1590 | No. 82 |
accession | description | class description | KNApSAcK metabolite in interactions |
# of diseases
(OMIM / KEGG) |
---|---|---|---|---|
P00352 | Retinal dehydrogenase 1 | Enzyme | C00000575 C00002656 | 0 / 0 |
B2RXH2 | Lysine-specific demethylase 4E | Enzyme | C00000575 C00002656 | 0 / 0 |
P10275 | Androgen receptor | NR3C4 | C00000575 C00002656 | 3 / 4 |
Q16236 | Nuclear factor erythroid 2-related factor 2 | Unclassified protein | C00000575 C00002656 | 0 / 0 |
P08684 | Cytochrome P450 3A4 | Cytochrome P450 3A4 | C00000575 C00002656 | 0 / 1 |
Q99714 | 3-hydroxyacyl-CoA dehydrogenase type-2 | Enzyme | C00000575 C00002656 | 3 / 3 |
P83916 | Chromobox protein homolog 1 | Unclassified protein | C00000575 C00002656 | 0 / 0 |
P16050 | Arachidonate 15-lipoxygenase | Enzyme | C00002656 | 0 / 0 |
P22001 | Potassium voltage-gated channel subfamily A member 3 | KCNA, Kv1.x (Shaker) | C00000575 | 0 / 0 |
Q9Y2D0 | Carbonic anhydrase 5B, mitochondrial | Lyase | C00002656 | 0 / 0 |
P35218 | Carbonic anhydrase 5A, mitochondrial | Lyase | C00002656 | 0 / 0 |
P43166 | Carbonic anhydrase 7 | Lyase | C00002656 | 0 / 0 |
Q03181 | Peroxisome proliferator-activated receptor delta | NR1C2 | C00002656 | 0 / 0 |
Q13526 | Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 | Enzyme | C00002656 | 0 / 0 |
P20813 | Cytochrome P450 2B6 | Cytochrome P450 2B6 | C00000575 | 1 / 0 |
P17658 | Potassium voltage-gated channel subfamily A member 6 | K | C00000575 | 0 / 0 |
P02545 | Prelamin-A/C | Unclassified protein | C00002656 | 11 / 10 |
P16473 | Thyrotropin receptor | Glycohormone receptor | C00000575 | 3 / 2 |
P10828 | Thyroid hormone receptor beta | NR1A2 | C00002656 | 3 / 1 |
P19793 | Retinoic acid receptor RXR-alpha | NR2B1 | C00002656 | 0 / 0 |
P00918 | Carbonic anhydrase 2 | Lyase | C00002656 | 1 / 2 |
P08183 | Multidrug resistance protein 1 | drug | C00000575 | 1 / 0 |
P11712 | Cytochrome P450 2C9 | Cytochrome P450 2C9 | C00000575 | 0 / 1 |
P54132 | Bloom syndrome protein | Enzyme | C00002656 | 1 / 2 |
Q9HAW7 | UDP-glucuronosyltransferase 1-7 | Enzyme | C00002656 | 0 / 0 |
P23280 | Carbonic anhydrase 6 | Lyase | C00002656 | 0 / 0 |
P16389 | Potassium voltage-gated channel subfamily A member 2 | KCNA, Kv1.x (Shaker) | C00000575 | 0 / 0 |
Q9ULX7 | Carbonic anhydrase 14 | Lyase | C00002656 | 0 / 0 |
P10635 | Cytochrome P450 2D6 | Cytochrome P450 2D6 | C00000575 | 1 / 0 |
P68871 | Hemoglobin subunit beta | Secreted protein | C00002656 | 4 / 4 |
O43570 | Carbonic anhydrase 12 | Lyase | C00002656 | 1 / 2 |
P11509 | Cytochrome P450 2A6 | Cytochrome P450 2A6 | C00000575 | 0 / 0 |
Q16665 | Hypoxia-inducible factor 1-alpha | Transcription Factor | C00002656 | 0 / 0 |
P39748 | Flap endonuclease 1 | Enzyme | C00002656 | 0 / 0 |
O75496 | Geminin | Unclassified protein | C00002656 | 0 / 0 |
P51151 | Ras-related protein Rab-9A | Unclassified protein | C00002656 | 0 / 0 |
P10145 | Interleukin-8 | Secreted protein | C00002656 | 0 / 0 |
P00915 | Carbonic anhydrase 1 | Lyase | C00002656 | 0 / 0 |
P63092 | Guanine nucleotide-binding protein G(s) subunit alpha isoforms short | Other membrane protein | C00000575 | 7 / 3 |
P49798 | Regulator of G-protein signaling 4 | Unclassified protein | C00002656 | 2 / 0 |
P04150 | Glucocorticoid receptor | NR3C1 | C00002656 | 0 / 1 |
Q96RI1 | Bile acid receptor | NR1H4 | C00002656 | 0 / 0 |
P56817 | Beta-secretase 1 | A1A | C00000575 | 0 / 0 |
Q16790 | Carbonic anhydrase 9 | Lyase | C00002656 | 0 / 1 |
Q99700 | Ataxin-2 | Unclassified protein | C00002656 | 1 / 1 |
P15428 | 15-hydroxyprostaglandin dehydrogenase [NAD(+)] | Enzyme | C00002656 | 2 / 2 |
O15118 | Niemann-Pick C1 protein | Unclassified protein | C00002656 | 1 / 1 |
Q01453 | Peripheral myelin protein 22 | Unclassified protein | C00002656 | 5 / 2 |
P51449 | Nuclear receptor ROR-gamma | Nuclear hormone receptor subfamily 1 group F member 3 | C00002656 | 0 / 0 |
Q96QE3 | ATPase family AAA domain-containing protein 5 | Unclassified protein | C00002656 | 0 / 0 |
P03372 | Estrogen receptor | NR3A1 | C00002656 | 1 / 1 |
P19838 | Nuclear factor NF-kappa-B p105 subunit | Transcription Factor | C00002656 | 0 / 0 |
P35354 | Prostaglandin G/H synthase 2 | Oxidoreductase | C00002656 | 0 / 3 |
P33261 | Cytochrome P450 2C19 | Cytochrome P450 2C19 | C00000575 | 1 / 1 |
Q9HAW8 | UDP-glucuronosyltransferase 1-10 | Enzyme | C00002656 | 0 / 0 |
P10636 | Microtubule-associated protein tau | Unclassified protein | C00002656 | 4 / 3 |
Q99549 | M-phase phosphoprotein 8 | Unclassified protein | C00002656 | 0 / 0 |
P48547 | Potassium voltage-gated channel subfamily C member 1 | K | C00000575 | 0 / 0 |
Q09470 | Potassium voltage-gated channel subfamily A member 1 | KCNA, Kv1.x (Shaker) | C00000575 | 1 / 1 |
P07451 | Carbonic anhydrase 3 | Lyase | C00002656 | 0 / 0 |
P22460 | Potassium voltage-gated channel subfamily A member 5 | KCNA, Kv1.x (Shaker) | C00000575 | 1 / 1 |
P35869 | Aryl hydrocarbon receptor | Transcription Factor | C00002656 | 0 / 0 |
P22748 | Carbonic anhydrase 4 | Lyase | C00002656 | 1 / 1 |
P42345 | Serine/threonine-protein kinase mTOR | Enzyme | C00002656 | 0 / 0 |
P46063 | ATP-dependent DNA helicase Q1 | Enzyme | C00002656 | 0 / 0 |
P40225 | Thrombopoietin | Unclassified protein | C00002656 | 1 / 1 |
Q96KQ7 | Histone-lysine N-methyltransferase EHMT2 | Enzyme | C00002656 | 0 / 0 |
O00255 | Menin | Unclassified protein | C00002656 | 2 / 5 |
Q03164 | Histone-lysine N-methyltransferase 2A | Enzyme | C00002656 | 1 / 2 |
O94925 | Glutaminase kidney isoform, mitochondrial | Enzyme | C00002656 | 0 / 0 |
gene | gene name | gene description | KNApSAcK metabolite in interactions |
---|---|---|---|
64782 | AEN, ISG20L1, pp12744 | apoptosis enhancing nuclease |
C00002656
|
217 | ALDH2, ALDH-E2, ALDHI, ALDM | aldehyde dehydrogenase 2 family (mitochondrial) (EC:1.2.1.3) |
C00002656
|
396 | ARHGDIA, GDIA1, NPHS8, RHOGDI, RHOGDI-1 | Rho GDP dissociation inhibitor (GDI) alpha |
C00002656
|
468 | ATF4, CREB-2, CREB2, TAXREB67, TXREB | activating transcription factor 4 |
C00002656
|
572 | BAD, BBC2, BCL2L8 | BCL2-associated agonist of cell death |
C00002656
|
27113 | BBC3, JFY-1, JFY1, PUMA | BCL2 binding component 3 |
C00002656
|
330 | BIRC3, AIP1, API2, CIAP2, HAIP1, HIAP1, MALT2, MIHC, RNF49, c-IAP2 | baculoviral IAP repeat containing 3 |
C00002656
|
664 | BNIP3, NIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 |
C00002656
|
79866 | BORA, C13orf34 | bora, aurora kinase A activator |
C00002656
|
7832 | BTG2, PC3, TIS21 | BTG family, member 2 |
C00002656
|
836 | CASP3, CPP32, CPP32B, SCA-1 | caspase 3, apoptosis-related cysteine peptidase (EC:3.4.22.56) |
C00002656
|
839 | CASP6, MCH2 | caspase 6, apoptosis-related cysteine peptidase (EC:3.4.22.59) |
C00002656
|
840 | CASP7, CASP-7, CMH-1, ICE-LAP3, LICE2, MCH3 | caspase 7, apoptosis-related cysteine peptidase (EC:3.4.22.60) |
C00002656
|
841 | CASP8, ALPS2B, CAP4, Casp-8, FLICE, MACH, MCH5 | caspase 8, apoptosis-related cysteine peptidase (EC:3.4.22.61) |
C00002656
|
842 | CASP9, APAF-3, APAF3, ICE-LAP6, MCH6, PPP1R56 | caspase 9, apoptosis-related cysteine peptidase (EC:3.4.22.62) |
C00002656
|
847 | CAT | catalase (EC:1.11.1.6) |
C00002656
|
6356 | CCL11, SCYA11 | chemokine (C-C motif) ligand 11 |
C00002656
|
6347 | CCL2, GDCF-2, HC11, HSMCR30, MCAF, MCP-1, MCP1, SCYA2, SMC-CF | chemokine (C-C motif) ligand 2 |
C00002656
|
6348 | CCL3, G0S19-1, LD78ALPHA, MIP-1-alpha, MIP1A, SCYA3 | chemokine (C-C motif) ligand 3 |
C00002656
|
6351 | CCL4, ACT2, AT744.1, G-26, HC21, LAG-1, LAG1, MIP-1-beta, MIP1B, MIP1B1, SCYA2, SCYA4 | chemokine (C-C motif) ligand 4 |
C00002656
|
6352 | CCL5, D17S136E, RANTES, SCYA5, SIS-delta, SISd, TCP228, eoCP | chemokine (C-C motif) ligand 5 |
C00002656
|
9134 | CCNE2, CYCE2 | cyclin E2 |
C00002656
|
899 | CCNF, FBX1, FBXO1 | cyclin F |
C00002656
|
942 | CD86, B7-2, B7.2, B70, CD28LG2, LAB72 | CD86 molecule |
C00002656
|
157313 | CDCA2, Repo-Man | cell division cycle associated 2 |
C00002656
|
1026 | CDKN1A, CAP20, CDKN1, CIP1, MDA-6, P21, SDI1, WAF1, p21CIP1 | cyclin-dependent kinase inhibitor 1A (p21, Cip1) |
C00002656
|
1058 | CENPA, CENP-A, CenH3 | centromere protein A |
C00002656
|
1277 | COL1A1, OI4 | collagen, type I, alpha 1 |
C00002656
|
1282 | COL4A1, HANAC, ICH, POREN1, arresten | collagen, type IV, alpha 1 |
C00002656
|
1436 | CSF1R, C-FMS, CD115, CSF-1R, CSFR, FIM2, FMS, HDLS, M-CSF-R | colony stimulating factor 1 receptor (EC:2.7.10.1) |
C00002656
|
1437 | CSF2, GMCSF | colony stimulating factor 2 (granulocyte-macrophage) |
C00002656
|
6387 | CXCL12, IRH, PBSF, SCYB12, SDF1, TLSF, TPAR1, SDF1A, SDF1B | chemokine (C-X-C motif) ligand 12 |
C00002656
|
54205 | CYCS, CYC, HCS, THC4 | cytochrome c, somatic |
C00002656
|
1543 | CYP1A1, AHH, AHRR, CP11, CYP1, P1-450, P450-C, P450DX | cytochrome P450, family 1, subfamily A, polypeptide 1 (EC:1.14.14.1) |
C00002656
|
1545 | CYP1B1, CP1B, CYPIB1, GLC3A, P4501B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 (EC:1.14.14.1) |
C00002656
|
24300 |
C00002656
|
||
1565 | CYP2D6, CPD6, CYP2D, CYP2D7AP, CYP2D7BP, CYP2D7P2, CYP2D8P2, CYP2DL1, CYPIID6, P450-DB1, P450C2D, P450DB1 | cytochrome P450, family 2, subfamily D, polypeptide 6 (EC:1.14.14.1) |
C00002656
|
1571 | CYP2E1, CPE1, CYP2E, P450-J, P450C2E | cytochrome P450, family 2, subfamily E, polypeptide 1 (EC:1.14.13.n7) |
C00002656
|
1576 | CYP3A4, CP33, CP34, CYP3A, CYP3A3, CYPIIIA3, CYPIIIA4, HLP, NF-25, P450C3, P450PCN1 | cytochrome P450, family 3, subfamily A, polypeptide 4 (EC:1.14.13.67 1.14.13.97 1.14.13.32 1.14.13.157) |
C00002656
|
1577 | CYP3A5, CP35, CYPIIIA5, P450PCN3, PCN3 | cytochrome P450, family 3, subfamily A, polypeptide 5 (EC:1.14.14.1) |
C00002656
|
3491 | CYR61, CCN1, GIG1, IGFBP10 | cysteine-rich, angiogenic inducer, 61 |
C00002656
|
1611 | DAP | death-associated protein |
C00002656
|
1649 | DDIT3, CEBPZ, CHOP, CHOP-10, CHOP10, GADD153 | DNA-damage-inducible transcript 3 |
C00002656
|
54541 | DDIT4, Dig2, REDD-1, REDD1 | DNA-damage-inducible transcript 4 |
C00002656
|
22943 | DKK1, DKK-1, SK | dickkopf WNT signaling pathway inhibitor 1 |
C00002656
|
3301 | DNAJA1, DJ-2, DjA1, HDJ2, HSDJ, HSJ2, HSPF4, NEDD7, hDJ-2 | DnaJ (Hsp40) homolog, subfamily A, member 1 |
C00002656
|
3337 | DNAJB1, HSPF1, Hdj1, Hsp40, RSPH16B, Sis1 | DnaJ (Hsp40) homolog, subfamily B, member 1 |
C00002656
|
1786 | DNMT1, ADCADN, AIM, CXXC9, DNMT, HSN1E, MCMT | DNA (cytosine-5-)-methyltransferase 1 (EC:2.1.1.37) |
C00002656
|
1788 | DNMT3A, DNMT3A2, M.HsaIIIA | DNA (cytosine-5-)-methyltransferase 3 alpha (EC:2.1.1.37) |
C00002656
|
1789 | DNMT3B, ICF, ICF1, M.HsaIIIB | DNA (cytosine-5-)-methyltransferase 3 beta (EC:2.1.1.37) |
C00002656
|
1999 | ELF3, EPR-1, ERT, ESE-1, ESX | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) |
C00002656
|
8772 | FADD, MORT1 | Fas (TNFRSF6)-associated via death domain |
C00002656
|
81610 | FAM83D, C20orf129, CHICA, dJ616B8.3 | family with sequence similarity 83, member D |
C00002656
|
26271 | FBXO5, EMI1, FBX5, Fbxo31 | F-box protein 5 |
C00002656
|
2335 | FN1, CIG, ED-B, FINC, FN, FNZ, GFND, GFND2, LETS, MSF | fibronectin 1 |
C00002656
|
2353 | FOS, AP-1, C-FOS, p55 | FBJ murine osteosarcoma viral oncogene homolog |
C00002656
|
2495 | FTH1, FHC, FTH, FTHL6, PIG15, PLIF | ferritin, heavy polypeptide 1 (EC:1.16.3.1) |
C00002656
|
1647 | GADD45A, DDIT1, GADD45 | growth arrest and DNA-damage-inducible, alpha |
C00002656
|
2623 | GATA1, ERYF1, GATA-1, GF-1, GF1, NF-E1, NFE1, XLANP, XLTDA, XLTT | GATA binding protein 1 (globin transcription factor 1) |
C00002656
|
2624 | GATA2, DCML, MONOMAC, NFE1B | GATA binding protein 2 |
C00002656
|
2730 | GCLM, GLCLR | glutamate-cysteine ligase, modifier subunit (EC:6.3.2.2) |
C00002656
|
9518 | GDF15, GDF-15, MIC-1, MIC1, NAG-1, PDF, PLAB, PTGFB | growth differentiation factor 15 |
C00002656
|
2937 | GSS, GSHS | glutathione synthetase (EC:6.3.2.3) |
C00002656
|
2944 | GSTM1, GST1, GSTM1-1, GSTM1a-1a, GSTM1b-1b, GTH4, GTM1, H-B, MU, MU-1 | glutathione S-transferase mu 1 (EC:2.5.1.18) |
C00002656
|
2993 | GYPA, CD235a, GPA, GPErik, GPSAT, HGpMiV, HGpMiXI, HGpSta(C), MN, MNS, PAS-2 | glycophorin A (MNS blood group) |
C00002656
|
3014 | H2AFX, H2A.X, H2A/X, H2AX | H2A histone family, member X |
C00002656
|
3043 | HBB, CD113t-C, beta-globin | hemoglobin, beta |
C00002656
|
3009 | HIST1H1B, H1, H1.5, H1B, H1F5, H1s-3 | histone cluster 1, H1b |
C00002656
|
3007 | HIST1H1D, H1.3, H1D, H1F3, H1s-2 | histone cluster 1, H1d |
C00002656
|
3008 | HIST1H1E, H1.4, H1E, H1F4, H1s-4, dJ221C16.5 | histone cluster 1, H1e |
C00002656
|
85235 | HIST1H2AH, H2A/S, H2AFALii, H2AH, dJ86C11.1 | histone cluster 1, H2ah |
C00002656
|
8329 | HIST1H2AI, H2A/c, H2AFC | histone cluster 1, H2ai |
C00002656
|
8331 | HIST1H2AJ, H2A/E, H2AFE, dJ160A22.4 | histone cluster 1, H2aj |
C00002656
|
8358 | HIST1H3B, H3/l, H3FL | histone cluster 1, H3b |
C00002656
|
8352 | HIST1H3C, H3.1, H3/c, H3FC | histone cluster 1, H3c |
C00002656
|
8359 | HIST1H4A, H4FA | histone cluster 1, H4a |
C00002656
|
8366 | HIST1H4B, H4/I, H4FI | histone cluster 1, H4b |
C00002656
|
8364 | HIST1H4C, H4/g, H4FG, dJ221C16.1 | histone cluster 1, H4c |
C00002656
|
8367 | HIST1H4E, H4/j, H4FJ | histone cluster 1, H4e |
C00002656
|
8361 | HIST1H4F, H4, H4/c, H4FC | histone cluster 1, H4f |
C00002656
|
8365 | HIST1H4H, H4/h, H4FH | histone cluster 1, H4h |
C00002656
|
8362 | HIST1H4K, H4/d, H4F2iii, H4FD, dJ160A22.1 | histone cluster 1, H4k |
C00002656
|
8337 | HIST2H2AA3, H2A, H2A.2, H2A/O, H2A/q, H2AFO, H2a-615, HIST2H2AA | histone cluster 2, H2aa3 |
C00002656
|
317772 | HIST2H2AB, H2AB | histone cluster 2, H2ab |
C00002656
|
8338 | HIST2H2AC, H2A, H2A-GL101, H2A/q, H2AFQ | histone cluster 2, H2ac |
C00002656
|
8370 | HIST2H4A, FO108, H4, H4/n, H4F2, H4FN, HIST2H4 | histone cluster 2, H4a |
C00002656
|
55355 | HJURP, FAKTS, URLC9, hFLEG1 | Holliday junction recognition protein |
C00002656
|
3145 | HMBS, PBG-D, PBGD, PORC, UPS | hydroxymethylbilane synthase (EC:2.5.1.61) |
C00002656
|
3148 | HMGB2, HMG2 | high mobility group box 2 |
C00002656
|
3162 | HMOX1, HMOX1D, HO-1, HSP32, bK286B10 | heme oxygenase (decycling) 1 (EC:1.14.99.3) |
C00002656
|
3306 | HSPA2, HSP70-2, HSP70-3 | heat shock 70kDa protein 2 |
C00002656
|
219844 | HYLS1, HLS | hydrolethalus syndrome 1 |
C00002656
|
3586 | IL10, CSIF, GVHDS, IL-10, IL10A, TGIF | interleukin 10 |
C00002656
|
3558 | IL2, IL-2, TCGF, lymphokine | interleukin 2 |
C00002656
|
3569 | IL6, BSF2, HGF, HSF, IFNB2, IL-6 | interleukin 6 (interferon, beta 2) |
C00002656
|
3576 | IL8, CXCL8, GCP-1, GCP1, LECT, LUCT, LYNAP, MDNCF, MONAP, NAF, NAP-1, NAP1 | interleukin 8 |
C00002656
|
3688 | ITGB1, CD29, FNRB, GPIIA, MDF2, MSK12, VLA-BETA, VLAB | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) |
C00002656
|
3689 | ITGB2, CD18, LAD, LCAMB, LFA-1, MAC-1, MF17, MFI7 | integrin, beta 2 (complement component 3 receptor 3 and 4 subunit) |
C00002656
|
182 | JAG1, AGS, AHD, AWS, CD339, HJ1, JAGL1 | jagged 1 |
C00002656
|
81930 | KIF18A, MS-KIF18A | kinesin family member 18A |
C00002656
|
4254 | KITLG, FPH2, KL-1, Kitl, MGF, SCF, SF, SHEP7 | KIT ligand |
C00002656
|
3910 | LAMA4, CMD1JJ, LAMA3, LAMA4*-1 | laminin, alpha 4 |
C00002656
|
11061 | LECT1, BRICD3, CHM-I, CHM1, MYETS1 | leukocyte cell derived chemotaxin 1 |
C00002656
|
4000 | LMNA, CDCD1, CDDC, CMD1A, CMT2B1, EMD2, FPL, FPLD, FPLD2, HGPS, IDC, LDP1, LFP, LGMD1B, LMN1, LMNC, LMNL1, PRO1 | lamin A/C |
C00002656
|
5594 | MAPK1, ERK, ERK2, ERT1, MAPK2, P42MAPK, PRKM1, PRKM2, p38, p40, p41, p41mapk | mitogen-activated protein kinase 1 (EC:2.7.11.24) |
C00002656
|
5595 | MAPK3, ERK-1, ERK1, ERT2, HS44KDAP, HUMKER1A, P44ERK1, P44MAPK, PRKM3, p44-ERK1, p44-MAPK | mitogen-activated protein kinase 3 (EC:2.7.11.24) |
C00002656
|
8932 | MBD2, DMTase, NY-CO-41 | methyl-CpG binding domain protein 2 |
C00002656
|
4257 | MGST1, GST12, MGST, MGST-I | microsomal glutathione S-transferase 1 (EC:2.5.1.18) |
C00002656
|
4323 | MMP14, MMP-14, MMP-X1, MT-MMP, MT-MMP_1, MT1-MMP, MT1MMP, MTMMP1, WNCHRS | matrix metallopeptidase 14 (membrane-inserted) (EC:3.4.24.80) |
C00002656
|
4324 | MMP15, MT2-MMP, MTMMP2, SMCP-2 | matrix metallopeptidase 15 (membrane-inserted) (EC:3.4.24.-) |
C00002656
|
4313 | MMP2, CLG4, CLG4A, MMP-II, MONA, TBE-1 | matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase) (EC:3.4.24.24) |
C00002656
|
4314 | MMP3, CHDS6, MMP-3, SL-1, STMY, STMY1, STR1 | matrix metallopeptidase 3 (stromelysin 1, progelatinase) (EC:3.4.24.17) |
C00002656
|
4318 | MMP9, CLG4B, GELB, MANDP2, MMP-9 | matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase) (EC:3.4.24.35) |
C00002656
|
4352 | MPL, C-MPL, CD110, MPLV, THCYT2, TPOR | myeloproliferative leukemia virus oncogene |
C00002656
|
4353 | MPO | myeloperoxidase (EC:1.11.2.2) |
C00002656
|
4609 | MYC, MRTL, MYCC, bHLHe39, c-Myc | v-myc avian myelocytomatosis viral oncogene homolog |
C00002656
|
4778 | NFE2, NF-E2, p45 | nuclear factor, erythroid 2 |
C00002656
|
4780 | NFE2L2, NRF2 | nuclear factor, erythroid 2-like 2 |
C00002656
|
1728 | NQO1, DHQU, DIA4, DTD, NMOR1, NMORI, QR1 | NAD(P)H dehydrogenase, quinone 1 (EC:1.6.5.2) |
C00002656
|
5036 | PA2G4, EBP1, HG4-1, p38-2G4 | proliferation-associated 2G4, 38kDa |
C00002656
|
142 | PARP1, ADPRT, ADPRT_1, ADPRT1, ARTD1, PARP, PARP-1, PPOL, pADPRT-1 | poly (ADP-ribose) polymerase 1 (EC:2.4.2.30) |
C00002656
|
25796 | PGLS, 6PGL | 6-phosphogluconolactonase (EC:3.1.1.31) |
C00002656
|
5429 | POLH, RAD30, RAD30A, XP-V, XPV | polymerase (DNA directed), eta (EC:2.7.7.7) |
C00002656
|
8493 | PPM1D, PP2C-DELTA, WIP1 | protein phosphatase, Mg2+/Mn2+ dependent, 1D (EC:3.1.3.16) |
C00002656
|
5052 | PRDX1, MSP23, NKEF-A, NKEFA, PAG, PAGA, PAGB, PRX1, PRXI, TDPX2 | peroxiredoxin 1 (EC:1.11.1.15) |
C00002656
|
5591 | PRKDC, DNA-PKcs, DNAPK, DNPK1, HYRC, HYRC1, XRCC7, p350 | protein kinase, DNA-activated, catalytic polypeptide (EC:2.7.11.1) |
C00002656
|
84722 | PSRC1, DDA3, FP3214 | proline/serine-rich coiled-coil 1 |
C00002656
|
9401 | RECQL4, RECQ4 | RecQ protein-like 4 (EC:3.6.4.12) |
C00002656
|
5970 | RELA, NFKB3, p65 | v-rel avian reticuloendotheliosis viral oncogene homolog A |
C00002656
|
860 | RUNX2, AML3, CBF-alpha-1, CBFA1, CCD, CCD1, CLCD, OSF-2, OSF2, PEA2aA, PEBP2aA | runt-related transcription factor 2 |
C00002656
|
27244 | SESN1, PA26, SEST1 | sestrin 1 |
C00002656
|
83667 | SESN2, HI95, SES2, SEST2 | sestrin 2 |
C00002656
|
6647 | SOD1, ALS, ALS1, IPOA, SOD, hSod1, homodimer | superoxide dismutase 1, soluble (EC:1.15.1.1) |
C00002656
|
6648 | SOD2, IPOB, MNSOD, MVCD6 | superoxide dismutase 2, mitochondrial (EC:1.15.1.1) |
C00002656
|
6688 | SPI1, OF, PU.1, SFPI1, SPI-1, SPI-A | spleen focus forming virus (SFFV) proviral integration oncogene |
C00002656
|
8614 | STC2, STC-2, STCRP | stanniocalcin 2 |
C00002656
|
7037 | TFRC, CD71, T9, TFR, TFR1, TR, TRFR, p90 | transferrin receptor |
C00002656
|
7077 | TIMP2, CSC-21K, DDC8 | TIMP metallopeptidase inhibitor 2 |
C00002656
|
25976 | TIPARP, ARTD14, PARP7, pART14 | TCDD-inducible poly(ADP-ribose) polymerase (EC:2.4.2.30) |
C00002656
|
7124 | TNF, DIF, TNF-alpha, TNFA, TNFSF2 | tumor necrosis factor |
C00002656
|
8795 | TNFRSF10B, CD262, DR5, KILLER, KILLER/DR5, TRAIL-R2, TRAILR2, TRICK2, TRICK2A, TRICK2B, TRICKB, ZTNFR9 | tumor necrosis factor receptor superfamily, member 10b |
C00002656
|
8793 | TNFRSF10D, CD264, DCR2, TRAIL-R4, TRAILR4, TRUNDD | tumor necrosis factor receptor superfamily, member 10d, decoy with truncated death domain |
C00002656
|
8718 | TNFRSF25, APO-3, DDR3, DR3, LARD, TNFRSF12, TR3, TRAMP, WSL-1, WSL-LR | tumor necrosis factor receptor superfamily, member 25 |
C00002656
|
3604 | TNFRSF9, 4-1BB, CD137, CDw137, ILA | tumor necrosis factor receptor superfamily, member 9 |
C00002656
|
8742 | TNFSF12, APO3L, DR3LG, TWEAK | tumor necrosis factor (ligand) superfamily, member 12 |
C00002656
|
7153 | TOP2A, TOP2, TP2A | topoisomerase (DNA) II alpha 170kDa (EC:5.99.1.3) |
C00002656
|
7157 | TP53, BCC7, LFS1, P53, TRP53 | tumor protein p53 |
C00002656
|
94241 | TP53INP1, SIP, TP53DINP1, TP53INP1A, TP53INP1B, Teap, p53DINP1 | tumor protein p53 inducible nuclear protein 1 |
C00002656
|
8717 | TRADD, Hs.89862 | TNFRSF1A-associated via death domain |
C00002656
|
9618 | TRAF4, CART1, MLN62, RNF83 | TNF receptor-associated factor 4 |
C00002656
|
286827 | TRIM59, MRF1, RNF104, TRIM57, TSBF1 | tripartite motif containing 59 |
C00002656
|
8989 | TRPA1, ANKTM1, FEPS | transient receptor potential cation channel, subfamily A, member 1 |
C00002656
|
7295 | TXN, TRDX, TRX, TRX1 | thioredoxin |
C00002656
|
7296 | TXNRD1, GRIM-12, TR, TR1, TRXR1, TXNR | thioredoxin reductase 1 (EC:1.8.1.9) |
C00002656
|
7474 | WNT5A, hWNT5A | wingless-type MMTV integration site family, member 5A |
C00002656
|
7486 | WRN, RECQ3, RECQL2, RECQL3 | Werner syndrome, RecQ helicase-like (EC:3.6.4.12) |
C00002656
|
OMIM | preferred title | UniProt |
---|---|---|
#300438 | 17-beta-hydroxysteroid dehydrogenase x deficiency |
Q99714
|
#219080 | Acth-independent macronodular adrenal hyperplasia; aimah |
P63092
|
#300068 | Androgen insensitivity syndrome; ais |
P10275
|
#312300 | Androgen insensitivity, partial; pais |
P10275
|
#612240 | Atrial fibrillation, familial, 7; atfb7 |
P22460
|
#613985 | Beta-thalassemia |
P68871
|
#603902 | Beta-thalassemia, dominant inclusion body type |
P68871
|
#210900 | Bloom syndrome; blm |
P54132
|
#115200 | Cardiomyopathy, dilated, 1a; cmd1a |
P02545
|
#212112 | Cardiomyopathy, dilated, with hypergonadotropic hypogonadism |
P02545
|
#118300 | Charcot-marie-tooth disease and deafness |
Q01453
|
#605588 | Charcot-marie-tooth disease, axonal, type 2b1; cmt2b1 |
P02545
|
#118220 | Charcot-marie-tooth disease, demyelinating, type 1a; cmt1a |
Q01453
|
#119900 | Digital clubbing, isolated congenital |
P15428
|
#609535 | Drug metabolism, poor, cyp2c19-related |
P33261
|
#608902 | Drug metabolism, poor, cyp2d6-related |
P10635
|
#614546 | Efavirenz, poor metabolism of |
P20813
|
#181350 | Emery-dreifuss muscular dystrophy 2, autosomal dominant; edmd2 |
P02545
|
#160120 | Episodic ataxia, type 1; ea1 |
Q09470
|
#615363 | Estrogen resistance; estrr |
P03372
|
#600274 | Frontotemporal dementia; ftd |
P10636
|
#139393 | Guillain-barre syndrome, familial; gbs |
Q01453
|
#605130 | Hairy elbows, short stature, facial dysmorphism, and developmental delay |
Q03164
|
#610140 | Heart-hand syndrome, slovenian type |
P02545
|
#140700 | Heinz body anemias |
P68871
|
#176670 | Hutchinson-gilford progeria syndrome; hgps |
P02545
|
#143860 | Hyperchlorhidrosis, isolated |
O43570
|
#145000 | Hyperparathyroidism 1; hrpt1 |
O00255
|
#603373 | Hyperthyroidism, familial gestational |
P16473
|
#609152 | Hyperthyroidism, nonautoimmune |
P16473
|
#145900 | Hypertrophic neuropathy of dejerine-sottas |
Q01453
|
#259100 | Hypertrophic osteoarthropathy, primary, autosomal recessive, 1; phoar1 |
P15428
|
#275200 | Hypothyroidism, congenital, nongoitrous, 1; chng1 |
P16473
|
#612244 | Inflammatory bowel disease 13; ibd13 |
P08183
|
#151660 | Lipodystrophy, familial partial, type 2; fpld2 |
P02545
|
#248370 | Mandibuloacral dysplasia with type a lipodystrophy; mada |
P02545
|
#174800 | Mccune-albright syndrome; mas |
P63092
|
#300705 | Mental retardation, x-linked 17; mrx17 |
Q99714
|
#300220 | Mental retardation, x-linked, syndromic 10; mrxs10 |
Q99714
|
#131100 | Multiple endocrine neoplasia, type i; men1 |
O00255
|
#613205 | Muscular dystrophy, congenital, lmna-related |
P02545
|
#159001 | Muscular dystrophy, limb-girdle, type 1b; lgmd1b |
P02545
|
#162500 | Neuropathy, hereditary, with liability to pressure palsies; hnpp |
Q01453
|
#257220 | Niemann-pick disease, type c1; npc1 |
O15118
|
#166350 | Osseous heteroplasia, progressive; poh |
P63092
|
#259730 | Osteopetrosis, autosomal recessive 3; optb3 |
P00918
|
#260540 | Parkinson-dementia syndrome |
P10636
|
#172700 | Pick disease of brain |
P10636
|
#102200 | Pituitary adenoma, growth hormone-secreting |
P63092
|
#103580 | Pseudohypoparathyroidism, type ia; php1a |
P63092
|
#603233 | Pseudohypoparathyroidism, type ib; php1b |
P63092
|
#612462 | Pseudohypoparathyroidism, type ic; php1c |
P63092
|
#275210 | Restrictive dermopathy, lethal |
P02545
|
#600852 | Retinitis pigmentosa 17; rp17 |
P22748
|
#604906 | Schizophrenia 9; sczd9 |
P49798
|
#181500 | Schizophrenia; sczd |
P49798
|
#603903 | Sickle cell anemia |
P68871
|
#313200 | Spinal and bulbar muscular atrophy, x-linked 1; smax1 |
P10275
|
#183090 | Spinocerebellar ataxia 2; sca2 |
Q99700
|
#601104 | Supranuclear palsy, progressive, 1; psnp1 |
P10636
|
#187950 | Thrombocythemia 1; thcyt1 |
P40225
|
#188570 | Thyroid hormone resistance, generalized, autosomal dominant; grth |
P10828
|
#274300 | Thyroid hormone resistance, generalized, autosomal recessive; grth |
P10828
|
#145650 | Thyroid hormone resistance, selective pituitary; prth |
P10828
|
KEGG | name | UniProt |
---|---|---|
H00033 | Adrenal carcinoma |
O00255
(related)
|
H00034 | Carcinoid |
O00255
(related)
|
H00045 | Malignant islet cell carcinoma |
O00255
(related)
|
H00246 | Primary hyperparathyroidism |
O00255
(related)
|
H01102 | Pituitary adenomas |
O00255
(related)
|
H00136 | Niemann-Pick disease type C (NPC) |
O15118
(related)
|
H01302 | Hyperchlorhidrosis isolated (HCHLH) |
O43570
(related)
|
H00021 | Renal cell carcinoma |
O43570
(marker)
Q16790 (marker) |
H00241 | Combined proximal and distal renal tubular acidosis (RTA type 3) |
P00918
(related)
|
H00436 | Osteopetrosis |
P00918
(related)
|
H00264 | Charcot-Marie-Tooth disease (CMT) |
P02545
(related)
Q01453 (related) |
H00294 | Dilated cardiomyopathy (DCM) |
P02545
(related)
|
H00420 | Familial partial lipodystrophy (FPL) |
P02545
(related)
|
H00563 | Emery-Dreifuss muscular dystrophy |
P02545
(related)
|
H00590 | Congenital muscular dystrophies (CMD/MDC) |
P02545
(related)
|
H00593 | Limb-girdle muscular dystrophy (LGMD) |
P02545
(related)
|
H00601 | Hutchinson-Gilford progeria syndrome |
P02545
(related)
|
H00663 | Restrictive dermopathy |
P02545
(related)
|
H00665 | Mandibuloacral dysplasia |
P02545
(related)
|
H01216 | Left ventricular noncompaction (LVNC) |
P02545
(related)
|
H00026 | Endometrial Cancer |
P03372
(marker)
|
H00599 | 46,XX disorders of sex development (Disorders related to androgen excess) |
P04150
(related)
|
H00036 | Osteosarcoma |
P08684
(marker)
|
H00024 | Prostate cancer |
P10275
(related)
|
H00062 | Spinal and bulbar muscular atrophy (SBMA) |
P10275
(related)
|
H00608 | 46,XY disorders of sex development (Disorders in androgen synthesis or action) |
P10275
(related)
|
H00609 | 46,XY disorders of sex development (Other) |
P10275
(related)
|
H00058 | Amyotrophic lateral sclerosis (ALS) |
P10636
(related)
|
H00077 | Progressive supranuclear palsy (PSP) |
P10636
(related)
|
H00078 | Frontotemporal lobar degeneration (FTLD) |
P10636
(related)
|
H00249 | Thyroid hormone resistance syndrome |
P10828
(related)
|
H01205 | Coumarin resistance |
P11712
(related)
|
H00457 | Primary hypertrophic osteoarthropathy (PHO) |
P15428
(related)
|
H01246 | Isolated congenital nail clubbing (ICNC) |
P15428
(related)
|
H00250 | Congenital nongoitrous hypothyroidism (CHNG) |
P16473
(related)
|
H01269 | Congenital hyperthyroidism |
P16473
(related)
|
H00731 | Atrial fibrillation |
P22460
(related)
|
H00527 | Retinitis pigmentosa (RP) |
P22748
(related)
|
H01171 | Poor drug metabolism (PM) |
P33261
(related)
|
H00017 | Esophageal cancer |
P35354
(related)
|
H00025 | Penile cancer |
P35354
(related)
|
H00046 | Cholangiocarcinoma |
P35354
(related)
|
H00227 | Congenital amegakaryocytic thrombocytopenia (CAMT) |
P40225
(marker)
|
H00094 | DNA repair defects |
P54132
(related)
|
H00296 | Defects in RecQ helicases |
P54132
(related)
|
H00244 | Pseudohypoparathyroidism |
P63092
(related)
|
H00441 | Progressive osseous heteroplasia (POH) |
P63092
(related)
|
H00501 | Fibrous dysplasia, polyostotic |
P63092
(related)
|
H00228 | Thalassemia |
P68871
(related)
|
H00229 | Sickle cell anemia (SCA) |
P68871
(related)
|
H00020 | Colorectal cancer |
P68871
(marker)
|
H00022 | Bladder cancer |
P68871
(marker)
|
H01296 | Hereditary neuropathy with liability to pressure palsies (HNPP) |
Q01453
(related)
|
H00001 | Acute lymphoblastic leukemia (ALL) (precursor B lymphoblastic leukemia) |
Q03164
(related)
Q03164 (marker) |
H00002 | Acute lymphoblastic leukemia (ALL) (precursor T lymphoblastic leukemia) |
Q03164
(related)
|
H00749 | Episodic ataxias |
Q09470
(related)
|
H00063 | Spinocerebellar ataxia (SCA) |
Q99700
(related)
|
H00480 | Non-syndromic X-linked mental retardation |
Q99714
(related)
|
H00658 | Syndromic X-linked mental retardation |
Q99714
(related)
|
H00925 | 2-Methyl-3-hydroxybutyryl-CoA dehydrogenase (MHBD) deficiency |
Q99714
(related)
|
MESH or OMIM | name |
KNApSAcK
metabolite |
---|---|---|
D006505 | Hepatitis |
C00000575
|
D010787 | Photosensitivity Disorders |
C00000575
|
D011565 | Psoriasis |
C00000575
|
D001855 | Bone Marrow Diseases |
C00002656
|
D002869 | Chromosome Aberrations |
C00002656
|
D019457 | Chromosome Breakage |
C00002656
|
D056486 | Drug-Induced Liver Injury |
C00002656
|
D004487 | Edema |
C00002656
|
D007674 | Kidney Diseases |
C00002656
|
D007680 | Kidney Neoplasms |
C00002656
|
D008548 | Melanosis |
C00002656
|
D048629 | Micronuclei, Chromosome-Defective |
C00002656
|
D009784 | Occupational Diseases |
C00002656
|
D011041 | Poisoning |
C00002656
|
D011123 | Polyploidy |
C00002656
|
D012140 | Respiratory Tract Diseases |
C00002656
|
D012772 | Shock, Septic |
C00002656
|