PCIDB

Moringa pterygosperma

Species

KNApSAcK Entry

Organism name Moringa pterygosperma
Genus Moringa
Family Moringaceae
Kingdom Plantae

NCBI taxonomy

Entry

Linked NCBI taxonomy name Moringa oleifera
Linked NCBI taxonomy ID 3735
Linked level species

Family

Family in NCBI taxonomy Moringaceae
ID 3733

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy Viridiplantae
ID 33090

Plant class

Plant class rosids
ID 71275

Metabolite list (1)

KNApSAcK ID name ChEMBL link CTD link # of proteins in
ChEMBL interaction
/ related OMIM
/ related KEGG DISEASE 		# of genes in
CTD interaction
/ related diseases 		KCF-S
cluster 		phytochemical
cluster 		figure
C00004634 External link 512 Rhamnetin
/ 7-Methoxyquercetin
/ 3,5,3',4'-Tetrahydroxy-7-methoxyflavone
/ 2-(3,4-Dihydroxyphenyl)-3,5-dihydroxy-7-methoxy-4H-1- benzopyran-4-one
CHEMBL312163
C063423
20 / 27 / 27 No. 3 No. 15

Human Protein / Gene in interactions

20 ChEMBL Protein in interactions

accession description class description KNApSAcK metabolite in interactions # of diseases
(OMIM / KEGG)
P45984 Mitogen-activated protein kinase 9 Jnk C00004634 0 / 0
P27361 Mitogen-activated protein kinase 3 Erk C00004634 0 / 0
P02545 Prelamin-A/C Unclassified protein C00004634 11 / 10
P10828 Thyroid hormone receptor beta NR1A2 C00004634 3 / 1
P04792 Heat shock protein beta-1 Unclassified protein C00004634 2 / 1
O15296 Arachidonate 15-lipoxygenase B Enzyme C00004634 0 / 0
P15121 Aldose reductase Enzyme C00004634 0 / 0
P04745 Alpha-amylase 1 Enzyme C00004634 0 / 0
P28482 Mitogen-activated protein kinase 1 Erk C00004634 0 / 0
P45983 Mitogen-activated protein kinase 8 Jnk C00004634 0 / 0
Q99714 3-hydroxyacyl-CoA dehydrogenase type-2 Enzyme C00004634 3 / 3
P08684 Cytochrome P450 3A4 Cytochrome P450 3A4 C00004634 0 / 1
P27695 DNA-(apurinic or apyrimidinic site) lyase Enzyme C00004634 0 / 0
P10636 Microtubule-associated protein tau Unclassified protein C00004634 4 / 3
Q9UBT6 DNA polymerase kappa Enzyme C00004634 0 / 0
B2RXH2 Lysine-specific demethylase 4E Enzyme C00004634 0 / 0
P46063 ATP-dependent DNA helicase Q1 Enzyme C00004634 0 / 0
Q9NUW8 Tyrosyl-DNA phosphodiesterase 1 Enzyme C00004634 1 / 1
O00255 Menin Unclassified protein C00004634 2 / 5
Q03164 Histone-lysine N-methyltransferase 2A Enzyme C00004634 1 / 2

Related Diseases

Diseases related to proteins in ChEMBL interactions

OMIM (27)

OMIM preferred title UniProt
#300438 17-beta-hydroxysteroid dehydrogenase x deficiency Q99714
#115200 Cardiomyopathy, dilated, 1a; cmd1a P02545
#212112 Cardiomyopathy, dilated, with hypergonadotropic hypogonadism P02545
#605588 Charcot-marie-tooth disease, axonal, type 2b1; cmt2b1 P02545
#606595 Charcot-marie-tooth disease, axonal, type 2f; cmt2f P04792
#181350 Emery-dreifuss muscular dystrophy 2, autosomal dominant; edmd2 P02545
#600274 Frontotemporal dementia; ftd P10636
#605130 Hairy elbows, short stature, facial dysmorphism, and developmental delay Q03164
#610140 Heart-hand syndrome, slovenian type P02545
#176670 Hutchinson-gilford progeria syndrome; hgps P02545
#145000 Hyperparathyroidism 1; hrpt1 O00255
#151660 Lipodystrophy, familial partial, type 2; fpld2 P02545
#248370 Mandibuloacral dysplasia with type a lipodystrophy; mada P02545
#300705 Mental retardation, x-linked 17; mrx17 Q99714
#300220 Mental retardation, x-linked, syndromic 10; mrxs10 Q99714
#131100 Multiple endocrine neoplasia, type i; men1 O00255
#613205 Muscular dystrophy, congenital, lmna-related P02545
#159001 Muscular dystrophy, limb-girdle, type 1b; lgmd1b P02545
#608634 Neuronopathy, distal hereditary motor, type iib; hmn2b P04792
#260540 Parkinson-dementia syndrome P10636
#172700 Pick disease of brain P10636
#275210 Restrictive dermopathy, lethal P02545
#607250 Spinocerebellar ataxia, autosomal recessive, with axonal neuropathy; scan1 Q9NUW8
#601104 Supranuclear palsy, progressive, 1; psnp1 P10636
#188570 Thyroid hormone resistance, generalized, autosomal dominant; grth P10828
#274300 Thyroid hormone resistance, generalized, autosomal recessive; grth P10828
#145650 Thyroid hormone resistance, selective pituitary; prth P10828

KEGG DISEASE (27)

KEGG name UniProt
H00033 Adrenal carcinoma O00255 (related)
H00034 Carcinoid O00255 (related)
H00045 Malignant islet cell carcinoma O00255 (related)
H00246 Primary hyperparathyroidism O00255 (related)
H01102 Pituitary adenomas O00255 (related)
H00264 Charcot-Marie-Tooth disease (CMT) P02545 (related)
H00294 Dilated cardiomyopathy (DCM) P02545 (related)
H00420 Familial partial lipodystrophy (FPL) P02545 (related)
H00563 Emery-Dreifuss muscular dystrophy P02545 (related)
H00590 Congenital muscular dystrophies (CMD/MDC) P02545 (related)
H00593 Limb-girdle muscular dystrophy (LGMD) P02545 (related)
H00601 Hutchinson-Gilford progeria syndrome P02545 (related)
H00663 Restrictive dermopathy P02545 (related)
H00665 Mandibuloacral dysplasia P02545 (related)
H01216 Left ventricular noncompaction (LVNC) P02545 (related)
H00856 Distal hereditary motor neuropathies (dHMN) P04792 (related)
H00036 Osteosarcoma P08684 (marker)
H00058 Amyotrophic lateral sclerosis (ALS) P10636 (related)
H00077 Progressive supranuclear palsy (PSP) P10636 (related)
H00078 Frontotemporal lobar degeneration (FTLD) P10636 (related)
H00249 Thyroid hormone resistance syndrome P10828 (related)
H00001 Acute lymphoblastic leukemia (ALL) (precursor B lymphoblastic leukemia) Q03164 (related)
Q03164 (marker)
H00002 Acute lymphoblastic leukemia (ALL) (precursor T lymphoblastic leukemia) Q03164 (related)
H00480 Non-syndromic X-linked mental retardation Q99714 (related)
H00658 Syndromic X-linked mental retardation Q99714 (related)
H00925 2-Methyl-3-hydroxybutyryl-CoA dehydrogenase (MHBD) deficiency Q99714 (related)
H00063 Spinocerebellar ataxia (SCA) Q9NUW8 (related)