Lysimachia nummularia

• Index
• Plant Species
• Natural Activity
• Metabolite list (10)
• Human Protein
  / Gene in interactions
• Related Diseases

Species

KNApSAcK Entry

Organism name	Lysimachia nummularia
Genus	Lysimachia
Family	Myrsinaceae
Kingdom	Plantae

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NCBI taxonomy

Entry

Linked NCBI taxonomy name	Lysimachia nummularia
Linked NCBI taxonomy ID	175113
Linked level	species

Family

Family in NCBI taxonomy	Primulaceae
ID	4335

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy	Viridiplantae
ID	33090

Plant class

Plant class	asterids
ID	71274

Natural Activity

List (9)

Species	Activity
Lysimachia nummularia L.	Antacid
Lysimachia nummularia L.	Antibacterial
Lysimachia nummularia L.	Antipyretic
Lysimachia nummularia L.	Antiseptic
Lysimachia nummularia L.	Antisialagogue
Lysimachia nummularia L.	Astringent
Lysimachia nummularia L.	Expectorant
Lysimachia nummularia L.	Hemolytic
Lysimachia nummularia L.	Vulnerary

Metabolite list (10)

KNApSAcK ID	name	ChEMBL link	CTD link	# of proteins in ChEMBL interaction / related OMIM / related KEGG DISEASE	# of genes in CTD interaction / related diseases	KCF-S cluster	phytochemical cluster	figure
C00005159	Kaempferol 3-rhamnosyl-(1->2)-galactoside	CHEMBL507493	C064704			No. 1	No. 15
C00005412	Quercetin 3-neohesperidoside / Quercetin 3-O-neohesperidoside	CHEMBL499824				No. 1	No. 15
C00005373	Hirsutrin / Isoquercetin / Isoquercetrin / (-)-Isoquercetrin / Quercetin 3-glucoside / Quercetin 3-O-beta-D-glucoside / Quercetin-3-O-beta-D-glucopyranoside / Quercetin 3-O-beta-D-glucopyranoside / (-)-Quercetin-3-O-beta-D-glucopyranoside	CHEMBL33027 CHEMBL309323 CHEMBL250450 CHEMBL251254 CHEMBL457304 CHEMBL1098724 CHEMBL2337335 CHEMBL2337336		38 / 43 / 34		No. 2	No. 15
C00005775	Syringetin 3-xyloside					No. 2	No. 15
C00005137	Trifolin / Kaempferol 3-O-beta-D-galactopyranoside	CHEMBL233930 CHEMBL453290 CHEMBL1572115	C066407	10 / 6 / 7	1 / 1	No. 2	No. 15
C00005769	Mearnsitrin / Myricetin 4'-O-methyl ether 3-O-alpha-L-rhamnopyranoside					No. 2	No. 15
C00005725	Myricetin 3-alpha-L-arabinofuranoside	CHEMBL497046				No. 2	No. 15
C00005776	Syringetin 3-galactoside	CHEMBL1600723 CHEMBL2165404		3 / 3 / 7		No. 2	No. 15
C00005206	Mauritianin / 3-O-[2,6-di-O-alpha-L-rhamnopyranosyl-beta-D-galactopyranosyl] kaempferol	CHEMBL362593 CHEMBL1454324 CHEMBL2005346	C069907	1 / 0 / 0		No. 5	No. 15
C00005444	Quercetin 3-(2Gal-rhamnosyl-robinobioside)	CHEMBL444468				No. 5	No. 15

Human Protein / Gene in interactions

46 ChEMBL Protein in interactions

accession	description	class description	KNApSAcK metabolite in interactions	# of diseases (OMIM / KEGG)
P07237	Protein disulfide-isomerase	Enzyme	C00005137 C00005373	0 / 0
P27695	DNA-(apurinic or apyrimidinic site) lyase	Enzyme	C00005137 C00005373	0 / 0
Q9UNA4	DNA polymerase iota	Enzyme	C00005137 C00005373	0 / 0
P14679	Tyrosinase	Oxidoreductase	C00005137 C00005373	4 / 2
Q9Y253	DNA polymerase eta	Enzyme	C00005137 C00005373	1 / 1
P15121	Aldose reductase	Enzyme	C00005137 C00005373	0 / 0
P09923	Intestinal-type alkaline phosphatase	Enzyme	C00005373	0 / 0
P10253	Lysosomal alpha-glucosidase	Hydrolase	C00005373	1 / 1
Q13526	Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1	Enzyme	C00005137	0 / 0
P02545	Prelamin-A/C	Unclassified protein	C00005373	11 / 10
P47989	Xanthine dehydrogenase/oxidase	Oxidoreductase	C00005373	1 / 1
P18825	Alpha-2C adrenergic receptor	Adrenergic receptor	C00005373	0 / 0
Q9NPH5	NADPH oxidase 4	Enzyme	C00005373	0 / 0
Q9NR56	Muscleblind-like protein 1	Unclassified protein	C00005373	1 / 0
P11387	DNA topoisomerase 1	Isomerase	C00005206	0 / 0
P41145	Kappa-type opioid receptor	Opioid receptor	C00005373	0 / 0
P36888	Receptor-type tyrosine-protein kinase FLT3	Pdgfr	C00005373	1 / 1
P39748	Flap endonuclease 1	Enzyme	C00005373	0 / 0
Q92830	Histone acetyltransferase KAT2A	Enzyme	C00005776	0 / 0
O75496	Geminin	Unclassified protein	C00005373	0 / 0
P41143	Delta-type opioid receptor	Opioid receptor	C00005373	0 / 0
P06746	DNA polymerase beta	Enzyme	C00005373	0 / 0
P35354	Prostaglandin G/H synthase 2	Oxidoreductase	C00005373	0 / 3
P04062	Glucosylceramidase	Enzyme	C00005373	6 / 4
P05186	Alkaline phosphatase, tissue-nonspecific isozyme	Enzyme	C00005373	3 / 1
Q99700	Ataxin-2	Unclassified protein	C00005137	1 / 1
P06280	Alpha-galactosidase A	Enzyme	C00005373	1 / 1
P28482	Mitogen-activated protein kinase 1	Erk	C00005373	0 / 0
P10696	Alkaline phosphatase, placental-like	Enzyme	C00005373	0 / 1
Q9UNQ0	ATP-binding cassette sub-family G member 2	ATP binding cassette	C00005373	2 / 0
Q96QE3	ATPase family AAA domain-containing protein 5	Unclassified protein	C00005137	0 / 0
P35372	Mu-type opioid receptor	Opioid receptor	C00005373	0 / 0
Q9UIF8	Bromodomain adjacent to zinc finger domain protein 2B	Unclassified protein	C00005373	0 / 0
Q16637	Survival motor neuron protein	Unclassified protein	C00005373	4 / 1
P10636	Microtubule-associated protein tau	Unclassified protein	C00005373	4 / 3
P08908	5-hydroxytryptamine receptor 1A	Serotonin receptor	C00005373	1 / 0
P34949	Mannose-6-phosphate isomerase	Enzyme	C00005373	1 / 1
Q9UBT6	DNA polymerase kappa	Enzyme	C00005373	0 / 0
B2RXH2	Lysine-specific demethylase 4E	Enzyme	C00005373	0 / 0
Q96KQ7	Histone-lysine N-methyltransferase EHMT2	Enzyme	C00005373	0 / 0
O00255	Menin	Unclassified protein	C00005776	2 / 5
Q03164	Histone-lysine N-methyltransferase 2A	Enzyme	C00005776	1 / 2
Q13951	Core-binding factor subunit beta	Unclassified protein	C00005373	0 / 1
Q01196	Runt-related transcription factor 1	Unclassified protein	C00005373	1 / 4
O94925	Glutaminase kidney isoform, mitochondrial	Enzyme	C00005373	0 / 0
P01215	Glycoprotein hormones alpha chain	Unclassified protein	C00005137	0 / 3

1 Gene in CTD interactions

gene	gene name	gene description	KNApSAcK metabolite in interactions
5320	PLA2G2A, MOM1, PLA2, PLA2B, PLA2L, PLA2S, PLAS1, sPLA2	phospholipase A2, group IIA (platelets, synovial fluid) (EC:3.1.1.4)	C00005137

Related Diseases

Diseases related to proteins in ChEMBL interactions

Diseases related to CTD interactions