Species

KNApSAcK Entry

Organism name Leitneria floridana
Genus Leitneria
Family Simaroubaceae
Kingdom Plantae

NCBI taxonomy

Entry

Linked NCBI taxonomy name Leitneria floridana
Linked NCBI taxonomy ID 83908
Linked level species

Family

Family in NCBI taxonomy Simaroubaceae
ID 23808

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy Viridiplantae
ID 33090

Plant class

Plant class rosids
ID 71275

Metabolite list (7)

KNApSAcK ID name ChEMBL link CTD link # of proteins in
ChEMBL interaction
/ related OMIM
/ related KEGG DISEASE
# of genes in
CTD interaction
/ related diseases
KCF-S
cluster
phytochemical
cluster
figure
C00007190 External link 512 (+)-Pinoresinol
CHEMBL267963
CHEMBL487611
CHEMBL460862
C103298
7 / 5 / 6 No. 38 No. 21
C00000627 External link 512 (-)-Lirioresinol B
/ (-)-Syringaresinol
CHEMBL361362
CHEMBL402653
1 / 0 / 0 No. 38 No. 21
C00002631 External link 512 (+)-Lirioresinol B
/ (+)-Syringaresinol
CHEMBL361362
CHEMBL402653
C042192
1 / 0 / 0 No. 38 No. 21
C00000602 External link 512 (+)-Lariciresinol
CHEMBL518421
2 / 1 / 1 No. 700 No. 21
C00003725 External link 512 Quassimarin
C013234
No. 704 No. 51
C00046799 External link 512 Leitneridanin B
/ (-)-Leitneridanin B
No. 2263
C00046798 External link 512 Leitneridanin A
/ (+)-Leitneridanin A
No. 4920

Human Protein / Gene in interactions

10 ChEMBL Protein in interactions

accession description class description KNApSAcK metabolite in interactions # of diseases
(OMIM / KEGG)
P11387 DNA topoisomerase 1 Isomerase C00000627 C00002631 0 / 0
P37231 Peroxisome proliferator-activated receptor gamma NR1C3 C00007190 5 / 3
P35354 Prostaglandin G/H synthase 2 Oxidoreductase C00007190 0 / 3
Q03181 Peroxisome proliferator-activated receptor delta NR1C2 C00007190 0 / 0
P10635 Cytochrome P450 2D6 Cytochrome P450 2D6 C00000602 1 / 0
P09917 Arachidonate 5-lipoxygenase Oxidoreductase C00007190 0 / 0
Q96QE3 ATPase family AAA domain-containing protein 5 Unclassified protein C00007190 0 / 0
P08684 Cytochrome P450 3A4 Cytochrome P450 3A4 C00000602 0 / 1
Q07869 Peroxisome proliferator-activated receptor alpha NR1C1 C00007190 0 / 0
Q9H0H5 Rac GTPase-activating protein 1 Unclassified protein C00007190 0 / 0

Related Diseases

Diseases related to proteins in ChEMBL interactions

OMIM (6)

OMIM preferred title UniProt
%606641 Body mass index; bmi P37231
#609338 Carotid intimal medial thickness 1 P37231
#608902 Drug metabolism, poor, cyp2d6-related P10635
#137800 Glioma susceptibility 1; glm1 P37231
#604367 Lipodystrophy, familial partial, type 3; fpld3 P37231
#601665 Obesity P37231

KEGG DISEASE (7)

KEGG name UniProt
H00036 Osteosarcoma P08684 (marker)
H00017 Esophageal cancer P35354 (related)
H00025 Penile cancer P35354 (related)
H00046 Cholangiocarcinoma P35354 (related)
H00032 Thyroid cancer P37231 (related)
H00409 Type II diabetes mellitus P37231 (related)
H00420 Familial partial lipodystrophy (FPL) P37231 (related)