Species

KNApSAcK Entry

Organism name Tripterygium wilfordii Hook F.(TwHF)
Genus Tripterygium
Family Celastraceae
Kingdom Plantae

NCBI taxonomy

Entry

Linked NCBI taxonomy name Tripterygium
Linked NCBI taxonomy ID 123484
Linked level genus

Family

Family in NCBI taxonomy Celastraceae
ID 4305

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy Viridiplantae
ID 33090

Plant class

Plant class rosids
ID 71275

Metabolite list (5)

KNApSAcK ID name ChEMBL link CTD link # of proteins in
ChEMBL interaction
/ related OMIM
/ related KEGG DISEASE
# of genes in
CTD interaction
/ related diseases
KCF-S
cluster
phytochemical
cluster
figure
C00000627 External link 512 (-)-Lirioresinol B
/ (-)-Syringaresinol
CHEMBL361362
CHEMBL402653
1 / 0 / 0 No. 38 No. 21
C00034730 External link 512 Tripterygiol
/ (+)-Tripterygiol
No. 38 No. 21
C00013118 External link 512 Euonine
/ Wilformine
/ (8alpha)-8-(Acetyloxy)-8-deoxoevonimine
CHEMBL498972
CHEMBL443712
C062678
No. 43
C00002637 External link 512 Antiarol
/ 3,4,5-Trimethoxyphenol
CHEMBL1319047
4 / 6 / 7 No. 856
C00034731 External link 512 Triptriolide
No. 3698 No. 41

Human Protein / Gene in interactions

5 ChEMBL Protein in interactions

accession description class description KNApSAcK metabolite in interactions # of diseases
(OMIM / KEGG)
P11387 DNA topoisomerase 1 Isomerase C00000627 0 / 0
P11473 Vitamin D3 receptor NR1I1 C00002637 2 / 3
P11021 78 kDa glucose-regulated protein Unclassified protein C00002637 0 / 0
P08684 Cytochrome P450 3A4 Cytochrome P450 3A4 C00002637 0 / 1
P10636 Microtubule-associated protein tau Unclassified protein C00002637 4 / 3

Related Diseases

Diseases related to proteins in ChEMBL interactions

OMIM (6)

OMIM preferred title UniProt
#600274 Frontotemporal dementia; ftd P10636
#607948 Mycobacterium tuberculosis, susceptibility to P11473
#260540 Parkinson-dementia syndrome P10636
#172700 Pick disease of brain P10636
#601104 Supranuclear palsy, progressive, 1; psnp1 P10636
#277440 Vitamin d-dependent rickets, type 2a; vddr2a P11473

KEGG DISEASE (7)

KEGG name UniProt
H00036 Osteosarcoma P08684 (marker)
H00058 Amyotrophic lateral sclerosis (ALS) P10636 (related)
H00077 Progressive supranuclear palsy (PSP) P10636 (related)
H00078 Frontotemporal lobar degeneration (FTLD) P10636 (related)
H00342 Tuberculosis P11473 (related)
H00784 Localized autosomal recessive hypotrichosis P11473 (related)
H01143 Vitamin D-dependent rickets P11473 (related)