Species

KNApSAcK Entry

Organism name Phyllanthus urinaria L.
Genus Phyllanthus
Family Phyllanthaceae
Kingdom Plantae

NCBI taxonomy

Entry

Linked NCBI taxonomy name Phyllanthus urinaria
Linked NCBI taxonomy ID 296035
Linked level species

Family

Family in NCBI taxonomy Phyllanthaceae
ID 233880

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy Viridiplantae
ID 33090

Plant class

Plant class rosids
ID 71275

Metabolite list (9)

KNApSAcK ID name ChEMBL link CTD link # of proteins in
ChEMBL interaction
/ related OMIM
/ related KEGG DISEASE
# of genes in
CTD interaction
/ related diseases
KCF-S
cluster
phytochemical
cluster
figure
C00037991 External link 512 Virgatusin
No. 38 No. 21
C00037045 External link 512 Dextrobursehernin
/ (+)-Dextrobursehernin
No. 223 No. 21
C00037251 External link 512 Heliobuphthalmin lactone
CHEMBL180970
CHEMBL182073
CHEMBL242011
2 / 1 / 1 No. 629 No. 21
C00030824 External link 512 Nirtetralin
/ (+)-Nirtetralin
CHEMBL453822
C475933
2 / 4 / 4 No. 1105
C00000707 External link 512 Hypophyllanthin
CHEMBL510130
CHEMBL2003455
2 / 4 / 4 No. 1105
C00037977 External link 512 Urinatetralin
No. 1142 No. 21
C00037423 External link 512 Lintetralin
/ (+)-Lintetralin
No. 1142 No. 21
C00030823 External link 512 Niranthin
C475932
No. 1232 No. 21
C00000706 External link 512 Phyllanthin
CHEMBL453568
CHEMBL1253999
3 / 9 / 9 No. 1232 No. 21

Human Protein / Gene in interactions

5 ChEMBL Protein in interactions

accession description class description KNApSAcK metabolite in interactions # of diseases
(OMIM / KEGG)
P25101 Endothelin-1 receptor Endothelin receptor C00000706 C00000707 C00030824 0 / 0
P24530 Endothelin B receptor Endothelin receptor C00000706 C00000707 C00030824 4 / 4
P10635 Cytochrome P450 2D6 Cytochrome P450 2D6 C00037251 1 / 0
P08684 Cytochrome P450 3A4 Cytochrome P450 3A4 C00037251 0 / 1
O14746 Telomerase reverse transcriptase Enzyme C00000706 5 / 5

Related Diseases

Diseases related to proteins in ChEMBL interactions

OMIM (10)

OMIM preferred title UniProt
#600501 Abcd syndrome; abcds P24530
#609135 Aplastic anemia O14746
#608902 Drug metabolism, poor, cyp2d6-related P10635
#613989 Dyskeratosis congenita, autosomal dominant, 2; dkca2 O14746
#142623 Hirschsprung disease, susceptibility to, 1; hscr1 P24530
#600155 Hirschsprung disease, susceptibility to, 2; hscr2 P24530
#615134 Melanoma, cutaneous malignant, susceptibility to, 9; cmm9 O14746
#614742 Pulmonary fibrosis and/or bone marrow failure, telomere-related, 1; pfbmft1 O14746
#178500 Pulmonary fibrosis, idiopathic; ipf O14746
#277580 Waardenburg syndrome, type 4a; ws4a P24530

KEGG DISEASE (10)

KEGG name UniProt
H00764 Cri du chat syndrome O14746 (related)
H01132 Aplastic anemia (AA) O14746 (related)
H01299 Idiopathic pulmonary fibrosis O14746 (related)
H00022 Bladder cancer O14746 (marker)
H00024 Prostate cancer O14746 (marker)
H00036 Osteosarcoma P08684 (marker)
H00054 Nasopharyngeal cancer P24530 (related)
H00759 Waardenburg syndrome (WS) P24530 (related)
H00823 ABCD syndrome P24530 (related)
H00910 Hirschsprung disease (HD) P24530 (related)