Species

KNApSAcK Entry

Organism name Phaseolus mungo
Genus Phaseolus
Family Fabaceae
Kingdom Plantae

NCBI taxonomy

Entry

Linked NCBI taxonomy name Vigna mungo
Linked NCBI taxonomy ID 3915
Linked level species

Family

Family in NCBI taxonomy Fabaceae
ID 3803

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy Viridiplantae
ID 33090

Plant class

Plant class rosids
ID 71275

Metabolite list (9)

KNApSAcK ID name ChEMBL link CTD link # of proteins in
ChEMBL interaction
/ related OMIM
/ related KEGG DISEASE
# of genes in
CTD interaction
/ related diseases
KCF-S
cluster
phytochemical
cluster
figure
C00009959 External link 512 4'-O-Methylkievitone
/ 5,7,2'-Trihydroxy-4'-methoxy-8-prenylisoflavanone
No. 28 No. 14
C00000108 External link 512 IAM
/ Indole-3-acetamide
/ 1H-Indole-3-acetamide
C015950
No. 710 No. 4
C00000107 External link 512 IAN
/ Indole-3-acetonitrile
CHEMBL1812654
C016516
No. 710 No. 4
C00000096 External link 512 9-Ribosyl-trans-zeatin
/ Zeatin-9-beta-D-ribofuranoside
No. 989
C00000100 External link 512 IAA
/ Indole-3-acetic acid
CHEMBL82411
C030737
3 / 0 / 0 2 / 1 No. 1432 No. 4
C00000094 External link 512 2iP
/ N6-(delta2-Isopentenyl)adenine
CHEMBL476189
C001478
5 / 2 / 3 18 / 0 No. 2879
C00000091 External link 512 trans-Zeatin
CHEMBL525239
D015026
2 / 3 / 2 0 / 1 No. 2879
C00000101 External link 512 IAA methyl ester
/ Methyl indole-3-acetate
No. 4225
C00000112 External link 512 Indole-3-carboxaldehyde
/ 1H-Indole-3-carboxaldehyde
CHEMBL147741
C012381
2 / 1 / 1 No. 4314

Human Protein / Gene in interactions

12 ChEMBL Protein in interactions

accession description class description KNApSAcK metabolite in interactions # of diseases
(OMIM / KEGG)
P10635 Cytochrome P450 2D6 Cytochrome P450 2D6 C00000094 1 / 0
Q16773 Kynurenine--oxoglutarate transaminase 1 Enzyme C00000100 0 / 0
P12268 Inosine-5'-monophosphate dehydrogenase 2 Oxidoreductase C00000112 0 / 0
P16473 Thyrotropin receptor Glycohormone receptor C00000091 3 / 2
P02768 Serum albumin Secreted protein C00000100 0 / 0
P11712 Cytochrome P450 2C9 Cytochrome P450 2C9 C00000094 0 / 1
Q9HBH1 Peptide deformylase, mitochondrial Enzyme C00000100 0 / 0
P05177 Cytochrome P450 1A2 Cytochrome P450 1A2 C00000094 0 / 0
P00374 Dihydrofolate reductase Oxidoreductase C00000112 1 / 1
P33261 Cytochrome P450 2C19 Cytochrome P450 2C19 C00000094 1 / 1
P08684 Cytochrome P450 3A4 Cytochrome P450 3A4 C00000094 0 / 1
P46063 ATP-dependent DNA helicase Q1 Enzyme C00000091 0 / 0

20 Gene in CTD interactions

gene gene name gene description KNApSAcK metabolite in interactions
440 ASNS, TS11 asparagine synthetase (glutamine-hydrolyzing) (EC:6.3.5.4) C00000094
694 BTG1 B-cell translocation gene 1, anti-proliferative C00000094
10681 GNB5, GB5 guanine nucleotide binding protein (G protein), beta 5 C00000094
182 JAG1, AGS, AHD, AWS, CD339, HJ1, JAGL1 jagged 1 C00000094
9818 NUPL1, PRO2463 nucleoporin like 1 C00000094
5142 PDE4B, DPDE4, PDE4B5, PDEIVB phosphodiesterase 4B, cAMP-specific (EC:3.1.4.17) C00000094
8544 PIR pirin (iron-binding nuclear protein) (EC:1.13.11.24) C00000094
5366 PMAIP1, APR, NOXA phorbol-12-myristate-13-acetate-induced protein 1 C00000094
9360 PPIG, CARS-Cyp, CYP, SCAF10, SRCyp peptidylprolyl isomerase G (cyclophilin G) (EC:5.2.1.8) C00000094
5782 PTPN12, PTP-PEST, PTPG1 protein tyrosine phosphatase, non-receptor type 12 (EC:3.1.3.48) C00000094
5774 PTPN3, PTP-H1, PTPH1 protein tyrosine phosphatase, non-receptor type 3 (EC:3.1.3.48) C00000094
6004 RGS16, A28-RGS14, A28-RGS14P, RGS-R regulator of G-protein signaling 16 C00000094
6016 RIT1, NS8, RIBB, RIT, ROC1 Ras-like without CAAX 1 C00000094
6286 S100P, MIG9 S100 calcium binding protein P C00000094
7029 TFDP2, DP2 transcription factor Dp-2 (E2F dimerization partner 2) C00000094
7127 TNFAIP2, B94, EXOC3L3 tumor necrosis factor, alpha-induced protein 2 C00000094
7296 TXNRD1, GRIM-12, TR, TR1, TRXR1, TXNR thioredoxin reductase 1 (EC:1.8.1.9) C00000094
7431 VIM, CTRCT30 vimentin C00000094
196 AHR, bHLHe76 aryl hydrocarbon receptor C00000100
405 ARNT, HIF-1-beta, HIF-1beta, HIF1-beta, HIF1B, HIF1BETA, TANGO, bHLHe2 aryl hydrocarbon receptor nuclear translocator C00000100

Related Diseases

Diseases related to proteins in ChEMBL interactions

OMIM (6)

OMIM preferred title UniProt
#609535 Drug metabolism, poor, cyp2c19-related P33261
#608902 Drug metabolism, poor, cyp2d6-related P10635
#603373 Hyperthyroidism, familial gestational P16473
#609152 Hyperthyroidism, nonautoimmune P16473
#275200 Hypothyroidism, congenital, nongoitrous, 1; chng1 P16473
#613839 Megaloblastic anemia due to dihydrofolate reductase deficiency P00374

KEGG DISEASE (6)

KEGG name UniProt
H01197 Dihydrofolate reductase (DHFR) deficiency P00374 (related)
H00036 Osteosarcoma P08684 (marker)
H01205 Coumarin resistance P11712 (related)
H00250 Congenital nongoitrous hypothyroidism (CHNG) P16473 (related)
H01269 Congenital hyperthyroidism P16473 (related)
H01171 Poor drug metabolism (PM) P33261 (related)

Diseases related to CTD interactions

2 disease in interactions with metabolites

MESH or OMIM name KNApSAcK
metabolite
D056486 Drug-Induced Liver Injury C00000100
D000647 Amnesia C00000091