Species

KNApSAcK Entry

Organism name Menispermum canadense L.
Genus Menispermum
Family Menispermaceae
Kingdom Plantae

NCBI taxonomy

Entry

Linked NCBI taxonomy name Menispermum canadense
Linked NCBI taxonomy ID 49681
Linked level species

Family

Family in NCBI taxonomy Menispermaceae
ID 3455

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy Viridiplantae
ID 33090

Plant class

Plant class eudicotyledons
ID 71240

Natural Activity

List (9)

Species Activity
Menispermum canadense L. Alterative
Menispermum canadense L. Cyanogenic
Menispermum canadense L. Diaphoretic
Menispermum canadense L. Diuretic
Menispermum canadense L. Laxative
Menispermum canadense L. Nervine
Menispermum canadense L. Poison
Menispermum canadense L. Stomachic
Menispermum canadense L. Tonic

Metabolite list (4)

KNApSAcK ID name ChEMBL link CTD link # of proteins in
ChEMBL interaction
/ related OMIM
/ related KEGG DISEASE
# of genes in
CTD interaction
/ related diseases
KCF-S
cluster
phytochemical
cluster
figure
C00026138 External link 512 N-Methyllindcarpine
/ (+)-N-Methyllindcarpine
No. 20 No. 4
C00025839 External link 512 Daurinoline
No. 89 No. 4
C00028131 External link 512 Dauricine
CHEMBL442717
CHEMBL1721004
CHEMBL1995008
C035934
2 / 2 / 2 1 / 2 No. 89 No. 4
C00025947 External link 512 N,N-Dimethyllindcarpine
No. 286 No. 4

Human Protein / Gene in interactions

2 ChEMBL Protein in interactions

accession description class description KNApSAcK metabolite in interactions # of diseases
(OMIM / KEGG)
Q12809 Potassium voltage-gated channel subfamily H member 2 KCNH, Kv10-12.x (Ether-a-go-go) C00028131 2 / 2
Q96QE3 ATPase family AAA domain-containing protein 5 Unclassified protein C00028131 0 / 0

1 Gene in CTD interactions

gene gene name gene description KNApSAcK metabolite in interactions
1576 CYP3A4, CP33, CP34, CYP3A, CYP3A3, CYPIIIA3, CYPIIIA4, HLP, NF-25, P450C3, P450PCN1 cytochrome P450, family 3, subfamily A, polypeptide 4 (EC:1.14.13.67 1.14.13.97 1.14.13.32 1.14.13.157) C00028131

Related Diseases

Diseases related to proteins in ChEMBL interactions

OMIM (2)

OMIM preferred title UniProt
#613688 Long qt syndrome 2; lqt2 Q12809
#609620 Short qt syndrome 1; sqt1 Q12809

KEGG DISEASE (2)

KEGG name UniProt
H00720 Long QT syndrome Q12809 (related)
H00725 Short QT syndrome Q12809 (related)

Diseases related to CTD interactions

2 disease in interactions with metabolites

MESH or OMIM name KNApSAcK
metabolite
D001145 Arrhythmias, Cardiac C00028131
D056486 Drug-Induced Liver Injury C00028131