Species

KNApSAcK Entry

Organism name Polemonium viscosum
Genus Polemonium
Family Polemoniaceae
Kingdom Plantae

NCBI taxonomy

Entry

Linked NCBI taxonomy name Polemonium viscosum
Linked NCBI taxonomy ID 64173
Linked level species

Family

Family in NCBI taxonomy Polemoniaceae
ID 24584

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy Viridiplantae
ID 33090

Plant class

Plant class asterids
ID 71274

Metabolite list (4)

KNApSAcK ID name ChEMBL link CTD link # of proteins in
ChEMBL interaction
/ related OMIM
/ related KEGG DISEASE
# of genes in
CTD interaction
/ related diseases
KCF-S
cluster
phytochemical
cluster
figure
C00022378 External link 512 19-Acetoxymanoyl oxide
No. 70
C00022377 External link 512 19-Hydroxymanoyl oxide
No. 70
C00000894 External link 512 Sclareol
CHEMBL294740
CHEMBL464176
CHEMBL1369540
C070760
14 / 19 / 18 No. 118 No. 46
C00023323 External link 512 13-Episclareol
/ 13-epi-Sclareol
CHEMBL294740
CHEMBL464176
CHEMBL1369540
14 / 19 / 18 No. 118 No. 46

Human Protein / Gene in interactions

14 ChEMBL Protein in interactions

accession description class description KNApSAcK metabolite in interactions # of diseases
(OMIM / KEGG)
Q99700 Ataxin-2 Unclassified protein C00000894 C00023323 1 / 1
P37840 Alpha-synuclein Unclassified protein C00000894 C00023323 4 / 2
P16473 Thyrotropin receptor Glycohormone receptor C00000894 C00023323 3 / 2
P11712 Cytochrome P450 2C9 Cytochrome P450 2C9 C00000894 C00023323 0 / 1
P00352 Retinal dehydrogenase 1 Enzyme C00000894 C00023323 0 / 0
P84022 Mothers against decapentaplegic homolog 3 Unclassified protein C00000894 C00023323 2 / 0
P43220 Glucagon-like peptide 1 receptor Glucagon-like peptide receptor C00000894 C00023323 0 / 0
P33261 Cytochrome P450 2C19 Cytochrome P450 2C19 C00000894 C00023323 1 / 1
P08684 Cytochrome P450 3A4 Cytochrome P450 3A4 C00000894 C00023323 0 / 1
Q9UNA4 DNA polymerase iota Enzyme C00000894 C00023323 0 / 0
P10636 Microtubule-associated protein tau Unclassified protein C00000894 C00023323 4 / 3
O00255 Menin Unclassified protein C00000894 C00023323 2 / 5
Q03164 Histone-lysine N-methyltransferase 2A Enzyme C00000894 C00023323 1 / 2
Q13148 TAR DNA-binding protein 43 Unclassified protein C00000894 C00023323 1 / 1

Related Diseases

Diseases related to proteins in ChEMBL interactions

OMIM (19)

OMIM preferred title UniProt
#612069 Amyotrophic lateral sclerosis 10, with or without frontotemporal dementia; als10 Q13148
#114500 Colorectal cancer; crc P84022
#127750 Dementia, lewy body; dlb P37840
#609535 Drug metabolism, poor, cyp2c19-related P33261
#600274 Frontotemporal dementia; ftd P10636
#605130 Hairy elbows, short stature, facial dysmorphism, and developmental delay Q03164
#145000 Hyperparathyroidism 1; hrpt1 O00255
#603373 Hyperthyroidism, familial gestational P16473
#609152 Hyperthyroidism, nonautoimmune P16473
#275200 Hypothyroidism, congenital, nongoitrous, 1; chng1 P16473
#613795 Loeys-dietz syndrome, type 3; lds3 P84022
#131100 Multiple endocrine neoplasia, type i; men1 O00255
#168601 Parkinson disease 1, autosomal dominant; park1 P37840
#605543 Parkinson disease 4, autosomal dominant; park4 P37840
#168600 Parkinson disease, late-onset; pd P37840
#260540 Parkinson-dementia syndrome P10636
#172700 Pick disease of brain P10636
#183090 Spinocerebellar ataxia 2; sca2 Q99700
#601104 Supranuclear palsy, progressive, 1; psnp1 P10636

KEGG DISEASE (18)

KEGG name UniProt
H00033 Adrenal carcinoma O00255 (related)
H00034 Carcinoid O00255 (related)
H00045 Malignant islet cell carcinoma O00255 (related)
H00246 Primary hyperparathyroidism O00255 (related)
H01102 Pituitary adenomas O00255 (related)
H00036 Osteosarcoma P08684 (marker)
H00058 Amyotrophic lateral sclerosis (ALS) P10636 (related)
Q13148 (related)
H00077 Progressive supranuclear palsy (PSP) P10636 (related)
H00078 Frontotemporal lobar degeneration (FTLD) P10636 (related)
H01205 Coumarin resistance P11712 (related)
H00250 Congenital nongoitrous hypothyroidism (CHNG) P16473 (related)
H01269 Congenital hyperthyroidism P16473 (related)
H01171 Poor drug metabolism (PM) P33261 (related)
H00057 Parkinson's disease (PD) P37840 (related)
H00066 Lewy body dementia (LBD) P37840 (related)
H00001 Acute lymphoblastic leukemia (ALL) (precursor B lymphoblastic leukemia) Q03164 (related)
Q03164 (marker)
H00002 Acute lymphoblastic leukemia (ALL) (precursor T lymphoblastic leukemia) Q03164 (related)
H00063 Spinocerebellar ataxia (SCA) Q99700 (related)