Species

KNApSAcK Entry

Organism name Artocarpus reticulatus Miq
Genus Artocarpus
Family Moraceae
Kingdom Plantae

NCBI taxonomy

Entry

Linked NCBI taxonomy name Artocarpus
Linked NCBI taxonomy ID 3488
Linked level genus

Family

Family in NCBI taxonomy Moraceae
ID 3487

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy Viridiplantae
ID 33090

Plant class

Plant class rosids
ID 71275

Metabolite list (3)

KNApSAcK ID name ChEMBL link CTD link # of proteins in
ChEMBL interaction
/ related OMIM
/ related KEGG DISEASE
# of genes in
CTD interaction
/ related diseases
KCF-S
cluster
phytochemical
cluster
figure
C00008834 External link 512 Afzelechin-3-O-alpha-L-rhamnoside
/ Afzelechin 3-O-alpha-L-rhamnopyranoside
CHEMBL517484
CHEMBL517149
2 / 0 / 3 No. 12 No. 14
C00000937 External link 512 Afzelechin
CHEMBL159303
CHEMBL1326092
7 / 4 / 12 No. 52 No. 14
C00002893 External link 512 Oxyresveratrol
/ 2,3,4,5'-Tetrahydroxystilbene
CHEMBL43065
20 / 32 / 49 No. 295 No. 13

Human Protein / Gene in interactions

25 ChEMBL Protein in interactions

accession description class description KNApSAcK metabolite in interactions # of diseases
(OMIM / KEGG)
P35354 Prostaglandin G/H synthase 2 Oxidoreductase C00000937 C00002893 C00008834 0 / 3
P23219 Prostaglandin G/H synthase 1 Oxidoreductase C00000937 C00002893 C00008834 0 / 0
Q16678 Cytochrome P450 1B1 Cytochrome P450 1B1 C00002893 4 / 4
P14780 Matrix metalloproteinase-9 M10A C00002893 2 / 2
P37840 Alpha-synuclein Unclassified protein C00002893 4 / 2
P04798 Cytochrome P450 1A1 Cytochrome P450 1A1 C00002893 0 / 0
P04637 Cellular tumor antigen p53 Transcription Factor C00002893 7 / 37
P17405 Sphingomyelin phosphodiesterase Enzyme C00002893 2 / 2
P38398 Breast cancer type 1 susceptibility protein Enzyme C00002893 4 / 2
P03956 Interstitial collagenase M10A C00002893 0 / 1
Q9UM73 ALK tyrosine kinase receptor TKL serine/threonine protein kinase STKR type 1 subfamily C00000937 1 / 1
P14679 Tyrosinase Oxidoreductase C00002893 4 / 2
P39900 Macrophage metalloelastase M10A C00002893 0 / 0
P45452 Collagenase 3 M10A C00002893 1 / 1
P05177 Cytochrome P450 1A2 Cytochrome P450 1A2 C00002893 0 / 0
P08253 72 kDa type IV collagenase M10A C00002893 1 / 3
Q96QE3 ATPase family AAA domain-containing protein 5 Unclassified protein C00002893 0 / 0
P08684 Cytochrome P450 3A4 Cytochrome P450 3A4 C00000937 0 / 1
O75164 Lysine-specific demethylase 4A Enzyme C00002893 0 / 0
P08254 Stromelysin-1 M10A C00002893 1 / 0
Q9UBT6 DNA polymerase kappa Enzyme C00000937 0 / 0
O75874 Isocitrate dehydrogenase [NADP] cytoplasmic Enzyme C00002893 1 / 0
O00255 Menin Unclassified protein C00000937 2 / 5
Q03164 Histone-lysine N-methyltransferase 2A Enzyme C00000937 1 / 2
Q13148 TAR DNA-binding protein 43 Unclassified protein C00002893 1 / 1

Related Diseases

Diseases related to proteins in ChEMBL interactions

OMIM (36)

OMIM preferred title UniProt
#202300 Adrenocortical carcinoma, hereditary; adcc P04637
#103470 Albinism, ocular, with sensorineural deafness P14679
#203100 Albinism, oculocutaneous, type ia; oca1a P14679
#606952 Albinism, oculocutaneous, type ib; oca1b P14679
#612069 Amyotrophic lateral sclerosis 10, with or without frontotemporal dementia; als10 Q13148
#614740 Basal cell carcinoma, susceptibility to, 7; bcc7 P04637
#114480 Breast cancer P38398
#604370 Breast-ovarian cancer, familial, susceptibility to, 1; brovca1 P38398
#614466 Coronary heart disease, susceptibility to, 6; chds6 P08254
#127750 Dementia, lewy body; dlb P37840
#133239 Esophageal cancer P04637
#137750 Glaucoma 1, open angle, a; glc1a Q16678
#231300 Glaucoma 3, primary congenital, a; glc3a Q16678
#137760 Glaucoma, primary open angle; poag Q16678
#137800 Glioma susceptibility 1; glm1 O75874
#605130 Hairy elbows, short stature, facial dysmorphism, and developmental delay Q03164
#145000 Hyperparathyroidism 1; hrpt1 O00255
#603932 Intervertebral disc disease; idd P14780
#151623 Li-fraumeni syndrome 1; lfs1 P04637
#211980 Lung cancer P04637
#613073 Metaphyseal anadysplasia 2; mandp2 P14780
#259600 Multicentric osteolysis, nodulosis, and arthropathy; mona P08253
#131100 Multiple endocrine neoplasia, type i; men1 O00255
#613014 Neuroblastoma, susceptibility to, 3; nblst3 Q9UM73
#257200 Niemann-pick disease, type a P17405
#607616 Niemann-pick disease, type b P17405
#167000 Ovarian cancer P38398
#614320 Pancreatic cancer, susceptibility to, 4; pnca4 P38398
#260500 Papilloma of choroid plexus; cpp P04637
#168601 Parkinson disease 1, autosomal dominant; park1 P37840
#605543 Parkinson disease 4, autosomal dominant; park4 P37840
#168600 Parkinson disease, late-onset; pd P37840
#604229 Peters anomaly Q16678
#601800 Skin/hair/eye pigmentation, variation in, 3; shep3 P14679
#602111 Spondyloepimetaphyseal dysplasia, missouri type P45452
#275355 Squamous cell carcinoma, head and neck; hnscc P04637

KEGG DISEASE (55)

KEGG name UniProt
H00033 Adrenal carcinoma O00255 (related)
P04637 (related)
H00034 Carcinoid O00255 (related)
H00045 Malignant islet cell carcinoma O00255 (related)
H00246 Primary hyperparathyroidism O00255 (related)
H01102 Pituitary adenomas O00255 (related)
H00028 Choriocarcinoma P03956 (related)
P04637 (related)
P08253 (related)
H00004 Chronic myeloid leukemia (CML) P04637 (related)
H00005 Chronic lymphocytic leukemia (CLL) P04637 (related)
H00006 Hairy-cell leukemia P04637 (related)
H00008 Burkitt lymphoma P04637 (related)
H00009 Adult T-cell leukemia P04637 (related)
H00010 Multiple myeloma P04637 (related)
H00013 Small cell lung cancer P04637 (related)
H00014 Non-small cell lung cancer P04637 (related)
Q9UM73 (related)
H00015 Malignant pleural mesothelioma P04637 (related)
H00016 Oral cancer P04637 (related)
P04637 (marker)
H00017 Esophageal cancer P04637 (related)
P04637 (marker)
P35354 (related)
H00018 Gastric cancer P04637 (related)
H00019 Pancreatic cancer P04637 (related)
P04637 (marker)
H00020 Colorectal cancer P04637 (related)
P04637 (marker)
H00022 Bladder cancer P04637 (related)
H00025 Penile cancer P04637 (related)
P04637 (marker)
P08253 (related)
P14780 (related)
P35354 (related)
H00026 Endometrial Cancer P04637 (related)
H00027 Ovarian cancer P04637 (related)
P38398 (related)
H00029 Vulvar cancer P04637 (related)
H00031 Breast cancer P04637 (related)
P38398 (related)
H00032 Thyroid cancer P04637 (related)
H00036 Osteosarcoma P04637 (related)
P08684 (marker)
H00038 Malignant melanoma P04637 (related)
P14679 (marker)
H00039 Basal cell carcinoma P04637 (related)
H00040 Squamous cell carcinoma P04637 (related)
H00041 Kaposi's sarcoma P04637 (related)
H00042 Glioma P04637 (related)
P04637 (marker)
H00044 Cancer of the anal canal P04637 (related)
H00046 Cholangiocarcinoma P04637 (related)
P35354 (related)
H00047 Gallbladder cancer P04637 (related)
H00048 Hepatocellular carcinoma P04637 (related)
H00055 Laryngeal cancer P04637 (related)
P04637 (marker)
H00881 Li-Fraumeni syndrome P04637 (related)
H01007 Choroid plexus papilloma P04637 (related)
H00021 Renal cell carcinoma P04637 (marker)
H00472 Torg-Winchester syndrome P08253 (related)
H00168 Oculocutaneous albinism (OCA) P14679 (related)
H00479 Metaphyseal dysplasias P14780 (related)
P45452 (related)
H00137 Niemann-Pick disease (NPD) typeA and B P17405 (related)
H00424 Defects in the degradation of sphingomyelin P17405 (related)
H00057 Parkinson's disease (PD) P37840 (related)
H00066 Lewy body dementia (LBD) P37840 (related)
H00001 Acute lymphoblastic leukemia (ALL) (precursor B lymphoblastic leukemia) Q03164 (related)
Q03164 (marker)
H00002 Acute lymphoblastic leukemia (ALL) (precursor T lymphoblastic leukemia) Q03164 (related)
H00058 Amyotrophic lateral sclerosis (ALS) Q13148 (related)
H00612 Primary open angle glaucoma Q16678 (related)
H01075 Peters anomaly Q16678 (related)
H01159 Anterior segment dysgenesis (ASD) Q16678 (related)
H01203 Primary congenital glaucoma (PCG) Q16678 (related)