Piper nigrum

• Index
• Plant Species
• Metabolite list (13)
• Human Protein
  / Gene in interactions
• Related Diseases

Species

KNApSAcK Entry

Organism name	Piper nigrum
Genus	Piper
Family	Piperaceae
Kingdom	Plantae

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NCBI taxonomy

Entry

Linked NCBI taxonomy name	Piper nigrum
Linked NCBI taxonomy ID	13216
Linked level	species

Family

Family in NCBI taxonomy	Piperaceae
ID	16739

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy	Viridiplantae
ID	33090

Plant class

Plant class	Magnoliophyta
ID	3398

Metabolite list (13)

KNApSAcK ID	name	ChEMBL link	CTD link	# of proteins in ChEMBL interaction / related OMIM / related KEGG DISEASE	# of genes in CTD interaction / related diseases	KCF-S cluster	phytochemical cluster	figure
C00001253	Palmitone / Hentriacontan-16-one					No. 115
C00034654	Retrofractamide A					No. 638
C00034630	Piperchabamide D					No. 638
C00034631	Pipercide / Retrofractamide B					No. 638
C00010929	1-Terpinen-5-ol					No. 1052	No. 35
C00010943	(-)-Carvotanacetone					No. 1824
C00010878	trans-(-)-p-Mentha-1(7),5-dien-2-ol					No. 1898	No. 35
C00011966	Sesquisabinene					No. 2854
C00043140	1-(1,6-Dioxo-2E,4E-decadienyl)piperidine					No. 3056
C00010888	p-Mentha-3,8-dien-1-ol					No. 3517
C00002065	Piperine / Bioperine / 1-Piperoylpiperidine	CHEMBL43185 CHEMBL1395862		32 / 47 / 64		No. 4209	No. 1
C00002076	Trichostachine	CHEMBL1087296				No. 4209	No. 1
C00034476	Dehydropipernonaline	CHEMBL483708 CHEMBL525259	C051966	1 / 1 / 2		No. 4209	No. 1

Human Protein / Gene in interactions

33 ChEMBL Protein in interactions

accession	description	class description	KNApSAcK metabolite in interactions	# of diseases (OMIM / KEGG)
P10635	Cytochrome P450 2D6	Cytochrome P450 2D6	C00002065	1 / 0
P04637	Cellular tumor antigen p53	Transcription Factor	C00002065	7 / 37
Q16637	Survival motor neuron protein	Unclassified protein	C00002065	4 / 1
Q99700	Ataxin-2	Unclassified protein	C00002065	1 / 1
P27338	Amine oxidase [flavin-containing] B	Oxidoreductase	C00002065	0 / 0
P02545	Prelamin-A/C	Unclassified protein	C00002065	11 / 10
P16473	Thyrotropin receptor	Glycohormone receptor	C00002065	3 / 2
P19793	Retinoic acid receptor RXR-alpha	NR2B1	C00002065	0 / 0
P21397	Amine oxidase [flavin-containing] A	Oxidoreductase	C00002065	1 / 1
P08183	Multidrug resistance protein 1	drug	C00002065	1 / 0
P11712	Cytochrome P450 2C9	Cytochrome P450 2C9	C00002065	0 / 1
P00352	Retinal dehydrogenase 1	Enzyme	C00002065	0 / 0
P17405	Sphingomyelin phosphodiesterase	Enzyme	C00002065	2 / 2
P51151	Ras-related protein Rab-9A	Unclassified protein	C00002065	0 / 0
P38398	Breast cancer type 1 susceptibility protein	Enzyme	C00002065	4 / 2
O94782	Ubiquitin carboxyl-terminal hydrolase 1	Enzyme	C00002065	0 / 0
P04150	Glucocorticoid receptor	NR3C1	C00002065	0 / 1
P37231	Peroxisome proliferator-activated receptor gamma	NR1C3	C00002065	5 / 3
Q8NER1	Transient receptor potential cation channel subfamily V member 1	TRPV (Vanilloid)	C00002065	0 / 0
Q96RI1	Bile acid receptor	NR1H4	C00002065	0 / 0
P28482	Mitogen-activated protein kinase 1	Erk	C00002065	0 / 0
P05177	Cytochrome P450 1A2	Cytochrome P450 1A2	C00002065	0 / 0
Q99714	3-hydroxyacyl-CoA dehydrogenase type-2	Enzyme	C00002065	3 / 3
P15428	15-hydroxyprostaglandin dehydrogenase [NAD(+)]	Enzyme	C00002065	2 / 2
O15118	Niemann-Pick C1 protein	Unclassified protein	C00002065	1 / 1
Q96QE3	ATPase family AAA domain-containing protein 5	Unclassified protein	C00002065	0 / 0
P33261	Cytochrome P450 2C19	Cytochrome P450 2C19	C00002065	1 / 1
P08684	Cytochrome P450 3A4	Cytochrome P450 3A4	C00002065	0 / 1
Q9UNA4	DNA polymerase iota	Enzyme	C00002065	0 / 0
Q16236	Nuclear factor erythroid 2-related factor 2	Unclassified protein	C00002065	0 / 0
P35869	Aryl hydrocarbon receptor	Transcription Factor	C00002065	0 / 0
P05362	Intercellular adhesion molecule 1	Adhesion	C00034476	1 / 2
B2RXH2	Lysine-specific demethylase 4E	Enzyme	C00002065	0 / 0

Related Diseases

Diseases related to proteins in ChEMBL interactions