Species

KNApSAcK Entry

Organism name Morus sp.
Genus Morus
Family Moraceae
Kingdom Plantae

NCBI taxonomy

Entry

Linked NCBI taxonomy name Moraceae
Linked NCBI taxonomy ID 3487
Linked level family

Family

Family in NCBI taxonomy Moraceae
ID 3487

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy Viridiplantae
ID 33090

Plant class

Plant class rosids
ID 71275

Metabolite list (26)

KNApSAcK ID name ChEMBL link CTD link # of proteins in
ChEMBL interaction
/ related OMIM
/ related KEGG DISEASE
# of genes in
CTD interaction
/ related diseases
KCF-S
cluster
phytochemical
cluster
figure
C00036154 External link 512 Moracin I
CHEMBL463435
1 / 2 / 2 No. 15 No. 15
C00036157 External link 512 Moracin N
CHEMBL465881
1 / 2 / 2 No. 15 No. 15
C00036161 External link 512 Moracin S
CHEMBL463125
2 / 0 / 3 No. 15 No. 15
C00036149 External link 512 Moracin C
CHEMBL2018876
4 / 1 / 0 No. 15 No. 15
C00036162 External link 512 Moracin T
No. 15 No. 15
C00036151 External link 512 Moracin E
No. 24 No. 15
C00036150 External link 512 Moracin D
CHEMBL463241
1 / 2 / 2 No. 24 No. 15
C00036163 External link 512 Moracin U
No. 24 No. 15
C00036155 External link 512 Moracin K
No. 24 No. 15
C00013461 External link 512 Sanggenone K
/ (-)-Sanggenone K
/ (-)-5,7-Dihydroxy-2-[5-hydroxy-2-methyl-2-(4-methyl-3-pentenyl)-2H-1-benzopyran-8-yl]-3-(3-methyl-2-butenyl)-4H-1-benzopyran-4-one
No. 44
C00014566 External link 512 Sanggenon T
No. 81 No. 20
C00011345 External link 512 Moracenin C
No. 81 No. 20
C00036148 External link 512 Moracin B
No. 210 No. 15
C00002404 External link 512 Mulberrofuran A
No. 319 No. 15
C00036168 External link 512 Mulberrofuran N
No. 319 No. 15
C00036166 External link 512 Mulberrofuran D
CHEMBL517247
1 / 0 / 0 No. 319 No. 15
C00036167 External link 512 Mulberrofuran L
CHEMBL459407
No. 319 No. 15
C00036165 External link 512 Mulberrofuran B
CHEMBL461067
No. 319 No. 15
C00036153 External link 512 Moracin H
No. 1617
C00036152 External link 512 Moracin G
No. 1617
C00036159 External link 512 Moracin Q
CHEMBL562169
No. 1617
C00036156 External link 512 Moracin L
No. 1617
C00036158 External link 512 Moracin P
/ (-)-Moracin P
CHEMBL380456
CHEMBL561971
6 / 2 / 2 No. 3977
C00036160 External link 512 Moracin R
/ (-)-Moracin R
No. 3977
C00014565 External link 512 Sanggenon S
No. 4698
C00014545 External link 512 Sanggenone R
No. 6335

Human Protein / Gene in interactions

13 ChEMBL Protein in interactions

accession description class description KNApSAcK metabolite in interactions # of diseases
(OMIM / KEGG)
P11511 Cytochrome P450 19A1 Cytochrome P450 19A1 C00036150 C00036154 C00036157 2 / 2
P18031 Tyrosine-protein phosphatase non-receptor type 1 Tyr C00036158 C00036166 0 / 0
P17405 Sphingomyelin phosphodiesterase Enzyme C00036158 2 / 2
Q08499 cAMP-specific 3',5'-cyclic phosphodiesterase 4D PDE_4D C00036149 1 / 0
P23219 Prostaglandin G/H synthase 1 Oxidoreductase C00036161 0 / 0
Q07343 cAMP-specific 3',5'-cyclic phosphodiesterase 4B PDE_4B C00036149 0 / 0
P51452 Dual specificity protein phosphatase 3 Ser_Thr_Tyr C00036158 0 / 0
Q16665 Hypoxia-inducible factor 1-alpha Transcription Factor C00036158 0 / 0
O75496 Geminin Unclassified protein C00036158 0 / 0
P43220 Glucagon-like peptide 1 receptor Glucagon-like peptide receptor C00036158 0 / 0
P35354 Prostaglandin G/H synthase 2 Oxidoreductase C00036161 0 / 3
O76083 High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A PDE_9A C00036149 0 / 0
O76074 cGMP-specific 3',5'-cyclic phosphodiesterase PDE_5A C00036149 0 / 0

Related Diseases

Diseases related to proteins in ChEMBL interactions

OMIM (5)

OMIM preferred title UniProt
#614613 Acrodysostosis 2, with or without hormone resistance; acrdys2 Q08499
#613546 Aromatase deficiency P11511
#139300 Aromatase excess syndrome; aexs P11511
#257200 Niemann-pick disease, type a P17405
#607616 Niemann-pick disease, type b P17405

KEGG DISEASE (7)

KEGG name UniProt
H00599 46,XX disorders of sex development (Disorders related to androgen excess) P11511 (related)
H00794 Aromatase excess syndrome P11511 (related)
H00137 Niemann-Pick disease (NPD) typeA and B P17405 (related)
H00424 Defects in the degradation of sphingomyelin P17405 (related)
H00017 Esophageal cancer P35354 (related)
H00025 Penile cancer P35354 (related)
H00046 Cholangiocarcinoma P35354 (related)