Species

KNApSAcK Entry

Organism name Ligusticum seguieri
Genus Ligusticum
Family Apiaceae
Kingdom Plantae

NCBI taxonomy

Entry

Linked NCBI taxonomy name Ligusticum
Linked NCBI taxonomy ID 49551
Linked level genus

Family

Family in NCBI taxonomy Apiaceae
ID 4037

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy Viridiplantae
ID 33090

Plant class

Plant class asterids
ID 71274

Metabolite list (5)

KNApSAcK ID name ChEMBL link CTD link # of proteins in
ChEMBL interaction
/ related OMIM
/ related KEGG DISEASE
# of genes in
CTD interaction
/ related diseases
KCF-S
cluster
phytochemical
cluster
figure
C00010994 External link 512 1,1,5-Trimethyl-2-formyl-6-((E)-3-hydroxymethyl-2-butenoyloxy)-2,4-cyclohexadiene
No. 1764
C00010984 External link 512 3-Hydroxy-4,6,6-trimethyl-1,4-Cyclohexadiene-1-carboxaldehyde 4-hydroxy-3-methylcrotonate acetate
No. 1764
C00010986 External link 512 1,1,5-Trimethyl-2-formyl-4-(3-methyl-2-butenoyloxy)-2,5-cyclohexadiene
No. 1764
C00010985 External link 512 1,1,5-Trimethyl-2-formyl-4-(E)-3-hydroxymethyl-2-butenoyloxy)-2,5-cyclohexadiene
No. 1764
C00002490 External link 512 Oxypeucedanin
CHEMBL510120
CHEMBL1510267
CHEMBL1609439
C031535
8 / 14 / 11 No. 2896 No. 25

Human Protein / Gene in interactions

8 ChEMBL Protein in interactions

accession description class description KNApSAcK metabolite in interactions # of diseases
(OMIM / KEGG)
P06746 DNA polymerase beta Enzyme C00002490 0 / 0
P02545 Prelamin-A/C Unclassified protein C00002490 11 / 10
P10828 Thyroid hormone receptor beta NR1A2 C00002490 3 / 1
P00352 Retinal dehydrogenase 1 Enzyme C00002490 0 / 0
O75496 Geminin Unclassified protein C00002490 0 / 0
P56817 Beta-secretase 1 A1A C00002490 0 / 0
B2RXH2 Lysine-specific demethylase 4E Enzyme C00002490 0 / 0
Q96KQ7 Histone-lysine N-methyltransferase EHMT2 Enzyme C00002490 0 / 0

Related Diseases

Diseases related to proteins in ChEMBL interactions

OMIM (14)

OMIM preferred title UniProt
#115200 Cardiomyopathy, dilated, 1a; cmd1a P02545
#212112 Cardiomyopathy, dilated, with hypergonadotropic hypogonadism P02545
#605588 Charcot-marie-tooth disease, axonal, type 2b1; cmt2b1 P02545
#181350 Emery-dreifuss muscular dystrophy 2, autosomal dominant; edmd2 P02545
#610140 Heart-hand syndrome, slovenian type P02545
#176670 Hutchinson-gilford progeria syndrome; hgps P02545
#151660 Lipodystrophy, familial partial, type 2; fpld2 P02545
#248370 Mandibuloacral dysplasia with type a lipodystrophy; mada P02545
#613205 Muscular dystrophy, congenital, lmna-related P02545
#159001 Muscular dystrophy, limb-girdle, type 1b; lgmd1b P02545
#275210 Restrictive dermopathy, lethal P02545
#188570 Thyroid hormone resistance, generalized, autosomal dominant; grth P10828
#274300 Thyroid hormone resistance, generalized, autosomal recessive; grth P10828
#145650 Thyroid hormone resistance, selective pituitary; prth P10828

KEGG DISEASE (11)

KEGG name UniProt
H00264 Charcot-Marie-Tooth disease (CMT) P02545 (related)
H00294 Dilated cardiomyopathy (DCM) P02545 (related)
H00420 Familial partial lipodystrophy (FPL) P02545 (related)
H00563 Emery-Dreifuss muscular dystrophy P02545 (related)
H00590 Congenital muscular dystrophies (CMD/MDC) P02545 (related)
H00593 Limb-girdle muscular dystrophy (LGMD) P02545 (related)
H00601 Hutchinson-Gilford progeria syndrome P02545 (related)
H00663 Restrictive dermopathy P02545 (related)
H00665 Mandibuloacral dysplasia P02545 (related)
H01216 Left ventricular noncompaction (LVNC) P02545 (related)
H00249 Thyroid hormone resistance syndrome P10828 (related)