Organism name | Apium spp. |
---|---|
Genus | Apium |
Family | Apiaceae |
Kingdom | Plantae |
Linked NCBI taxonomy name | Apium |
---|---|
Linked NCBI taxonomy ID | 4044 |
Linked level | genus |
Family in NCBI taxonomy | Apiaceae |
---|---|
ID | 4037 |
Kingdom (Superkingdom) in NCBI taxonomy | Viridiplantae |
---|---|
ID | 33090 |
Plant class | asterids |
---|---|
ID | 71274 |
KNApSAcK ID | name | ChEMBL link | CTD link |
# of proteins in
ChEMBL interaction / related OMIM / related KEGG DISEASE |
# of genes in
CTD interaction / related diseases |
KCF-S
cluster |
phytochemical
cluster |
figure |
---|---|---|---|---|---|---|---|---|
C00006833 |
Cyanidin 3-[6-(6-ferulylglucosyl)-2-xylosylgalactoside]
|
No. 7 | No. 15 | |||||
C00002503 |
Umbelliferon
/ Umbelliferone / 7-Hydroxycoumarin |
CHEMBL51628
|
C031477
|
39 / 33 / 32 | 9 / 0 | No. 1030 | No. 25 |
accession | description | class description | KNApSAcK metabolite in interactions |
# of diseases
(OMIM / KEGG) |
---|---|---|---|---|
P22310 | UDP-glucuronosyltransferase 1-4 | Enzyme | C00002503 | 3 / 0 |
Q9HAW8 | UDP-glucuronosyltransferase 1-10 | Enzyme | C00002503 | 0 / 0 |
Q99700 | Ataxin-2 | Unclassified protein | C00002503 | 1 / 1 |
P35354 | Prostaglandin G/H synthase 2 | Oxidoreductase | C00002503 | 0 / 3 |
P04062 | Glucosylceramidase | Enzyme | C00002503 | 6 / 4 |
P10253 | Lysosomal alpha-glucosidase | Hydrolase | C00002503 | 1 / 1 |
P29466 | Caspase-1 | C14 | C00002503 | 0 / 0 |
P04406 | Glyceraldehyde-3-phosphate dehydrogenase | Enzyme | C00002503 | 0 / 0 |
P47989 | Xanthine dehydrogenase/oxidase | Oxidoreductase | C00002503 | 1 / 1 |
P00918 | Carbonic anhydrase 2 | Lyase | C00002503 | 1 / 2 |
P00352 | Retinal dehydrogenase 1 | Enzyme | C00002503 | 0 / 0 |
P28845 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | Enzyme | C00002503 | 1 / 1 |
O43570 | Carbonic anhydrase 12 | Lyase | C00002503 | 1 / 2 |
P39748 | Flap endonuclease 1 | Enzyme | C00002503 | 0 / 0 |
Q92830 | Histone acetyltransferase KAT2A | Enzyme | C00002503 | 0 / 0 |
O75496 | Geminin | Unclassified protein | C00002503 | 0 / 0 |
P54855 | UDP-glucuronosyltransferase 2B15 | Enzyme | C00002503 | 0 / 0 |
P18405 | 3-oxo-5-alpha-steroid 4-dehydrogenase 1 | Oxidoreductase | C00002503 | 0 / 0 |
P15121 | Aldose reductase | Enzyme | C00002503 | 0 / 0 |
P00915 | Carbonic anhydrase 1 | Lyase | C00002503 | 0 / 0 |
P83916 | Chromobox protein homolog 1 | Unclassified protein | C00002503 | 0 / 0 |
P14679 | Tyrosinase | Oxidoreductase | C00002503 | 4 / 2 |
P06280 | Alpha-galactosidase A | Enzyme | C00002503 | 1 / 1 |
P56817 | Beta-secretase 1 | A1A | C00002503 | 0 / 0 |
Q16790 | Carbonic anhydrase 9 | Lyase | C00002503 | 0 / 1 |
Q99714 | 3-hydroxyacyl-CoA dehydrogenase type-2 | Enzyme | C00002503 | 3 / 3 |
P15428 | 15-hydroxyprostaglandin dehydrogenase [NAD(+)] | Enzyme | C00002503 | 2 / 2 |
Q9HAW9 | UDP-glucuronosyltransferase 1-8 | Enzyme | C00002503 | 0 / 0 |
Q9Y4X1 | UDP-glucuronosyltransferase 2A1 | Enzyme | C00002503 | 0 / 0 |
P22303 | Acetylcholinesterase | Hydrolase | C00002503 | 1 / 0 |
Q00796 | Sorbitol dehydrogenase | Enzyme | C00002503 | 0 / 0 |
P55210 | Caspase-7 | C14 | C00002503 | 0 / 0 |
P22309 | UDP-glucuronosyltransferase 1-1 | Enzyme | C00002503 | 5 / 1 |
P80365 | Corticosteroid 11-beta-dehydrogenase isozyme 2 | Enzyme | C00002503 | 1 / 1 |
B2RXH2 | Lysine-specific demethylase 4E | Enzyme | C00002503 | 0 / 0 |
Q9NUW8 | Tyrosyl-DNA phosphodiesterase 1 | Enzyme | C00002503 | 1 / 1 |
O00255 | Menin | Unclassified protein | C00002503 | 2 / 5 |
Q03164 | Histone-lysine N-methyltransferase 2A | Enzyme | C00002503 | 1 / 2 |
O94925 | Glutaminase kidney isoform, mitochondrial | Enzyme | C00002503 | 0 / 0 |
gene | gene name | gene description | KNApSAcK metabolite in interactions |
---|---|---|---|
8644 | AKR1C3, DD3, DDX, HA1753, HAKRB, HAKRe, HSD17B5, PGFS, hluPGFS | aldo-keto reductase family 1, member C3 (EC:1.3.1.20 1.1.1.188 1.1.1.239 1.1.1.64 1.1.1.112 1.1.1.357) |
C00002503
|
8574 | AKR7A2, AFAR, AFAR1, AFB1-AR1, AKR7 | aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase) (EC:1.1.1.n11) |
C00002503
|
581 | BAX, BCL2L4 | BCL2-associated X protein |
C00002503
|
596 | BCL2, Bcl-2, PPP1R50 | B-cell CLL/lymphoma 2 |
C00002503
|
595 | CCND1, BCL1, D11S287E, PRAD1, U21B31 | cyclin D1 |
C00002503
|
1548 | CYP2A6, CPA6, CYP2A, CYP2A3, CYPIIA6, P450C2A, P450PB | cytochrome P450, family 2, subfamily A, polypeptide 6 (EC:1.14.14.1) |
C00002503
|
6817 | SULT1A1, HAST1/HAST2, P-PST, PST, ST1A1, ST1A3, STP, STP1, TSPST1 | sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1 (EC:2.8.2.1) |
C00002503
|
54600 | UGT1A9, HLUGP4, LUGP4, UDPGT, UDPGT_1-9, UGT-1I, UGT1-09, UGT1-9, UGT1.9, UGT1AI, UGT1I | UDP glucuronosyltransferase 1 family, polypeptide A9 (EC:2.4.1.17) |
C00002503
|
7366 | UGT2B15, HLUG4, UDPGT_2B8, UDPGT2B15, UDPGTH3, UGT2B8 | UDP glucuronosyltransferase 2 family, polypeptide B15 (EC:2.4.1.17) |
C00002503
|
OMIM | preferred title | UniProt |
---|---|---|
#300438 | 17-beta-hydroxysteroid dehydrogenase x deficiency |
Q99714
|
#103470 | Albinism, ocular, with sensorineural deafness |
P14679
|
#203100 | Albinism, oculocutaneous, type ia; oca1a |
P14679
|
#606952 | Albinism, oculocutaneous, type ib; oca1b |
P14679
|
#218030 | Apparent mineralocorticoid excess; ame |
P80365
|
#601816 | Bilirubin, serum level of, quantitative trait locus 1; biliqtl1 |
P22309
|
#604931 | Cortisone reductase deficiency 1; cortrd1 |
P28845
|
#218800 | Crigler-najjar syndrome, type i |
P22309
P22310 |
#606785 | Crigler-najjar syndrome, type ii |
P22309
P22310 |
#119900 | Digital clubbing, isolated congenital |
P15428
|
#301500 | Fabry disease |
P06280
|
#608013 | Gaucher disease, perinatal lethal |
P04062
|
#230800 | Gaucher disease, type i |
P04062
|
#230900 | Gaucher disease, type ii |
P04062
|
#231000 | Gaucher disease, type iii |
P04062
|
#231005 | Gaucher disease, type iiic |
P04062
|
#143500 | Gilbert syndrome |
P22309
P22310 |
#232300 | Glycogen storage disease ii |
P10253
|
#605130 | Hairy elbows, short stature, facial dysmorphism, and developmental delay |
Q03164
|
#237900 | Hyperbilirubinemia, transient familial neonatal; hblrtfn |
P22309
|
#143860 | Hyperchlorhidrosis, isolated |
O43570
|
#145000 | Hyperparathyroidism 1; hrpt1 |
O00255
|
#259100 | Hypertrophic osteoarthropathy, primary, autosomal recessive, 1; phoar1 |
P15428
|
#300705 | Mental retardation, x-linked 17; mrx17 |
Q99714
|
#300220 | Mental retardation, x-linked, syndromic 10; mrxs10 |
Q99714
|
#131100 | Multiple endocrine neoplasia, type i; men1 |
O00255
|
#259730 | Osteopetrosis, autosomal recessive 3; optb3 |
P00918
|
#168600 | Parkinson disease, late-onset; pd |
P04062
|
#601800 | Skin/hair/eye pigmentation, variation in, 3; shep3 |
P14679
|
#183090 | Spinocerebellar ataxia 2; sca2 |
Q99700
|
#607250 | Spinocerebellar ataxia, autosomal recessive, with axonal neuropathy; scan1 |
Q9NUW8
|
#278300 | Xanthinuria, type i |
P47989
|
#112100 | Yt blood group antigen |
P22303
|
KEGG | name | UniProt |
---|---|---|
H00033 | Adrenal carcinoma |
O00255
(related)
|
H00034 | Carcinoid |
O00255
(related)
|
H00045 | Malignant islet cell carcinoma |
O00255
(related)
|
H00246 | Primary hyperparathyroidism |
O00255
(related)
|
H01102 | Pituitary adenomas |
O00255
(related)
|
H01302 | Hyperchlorhidrosis isolated (HCHLH) |
O43570
(related)
|
H00021 | Renal cell carcinoma |
O43570
(marker)
Q16790 (marker) |
H00241 | Combined proximal and distal renal tubular acidosis (RTA type 3) |
P00918
(related)
|
H00436 | Osteopetrosis |
P00918
(related)
|
H00066 | Lewy body dementia (LBD) |
P04062
(related)
|
H00126 | Gaucher disease |
P04062
(related)
|
H00426 | Defects in the degradation of ganglioside |
P04062
(related)
|
H00810 | Progressive myoclonic epilepsy (PME) |
P04062
(related)
|
H00125 | Fabry disease |
P06280
(related)
|
H00069 | Glycogen storage diseases (GSD) |
P10253
(related)
|
H00168 | Oculocutaneous albinism (OCA) |
P14679
(related)
|
H00038 | Malignant melanoma |
P14679
(marker)
|
H00457 | Primary hypertrophic osteoarthropathy (PHO) |
P15428
(related)
|
H01246 | Isolated congenital nail clubbing (ICNC) |
P15428
(related)
|
H00208 | Hyperbilirubinemia |
P22309
(related)
|
H01111 | Cortisone reductase deficiency (CRD) |
P28845
(related)
|
H00017 | Esophageal cancer |
P35354
(related)
|
H00025 | Penile cancer |
P35354
(related)
|
H00046 | Cholangiocarcinoma |
P35354
(related)
|
H00192 | Xanthinuria |
P47989
(related)
|
H00259 | Apparent mineralocorticoid excess syndrome |
P80365
(related)
|
H00001 | Acute lymphoblastic leukemia (ALL) (precursor B lymphoblastic leukemia) |
Q03164
(related)
Q03164 (marker) |
H00002 | Acute lymphoblastic leukemia (ALL) (precursor T lymphoblastic leukemia) |
Q03164
(related)
|
H00063 | Spinocerebellar ataxia (SCA) |
Q99700
(related)
Q9NUW8 (related) |
H00480 | Non-syndromic X-linked mental retardation |
Q99714
(related)
|
H00658 | Syndromic X-linked mental retardation |
Q99714
(related)
|
H00925 | 2-Methyl-3-hydroxybutyryl-CoA dehydrogenase (MHBD) deficiency |
Q99714
(related)
|