Species

KNApSAcK Entry

Organism name Asarum europaeum
Genus Asarum
Family Aristolochiaceae
Kingdom Plantae

NCBI taxonomy

Entry

Linked NCBI taxonomy name Asarum europaeum
Linked NCBI taxonomy ID 49456
Linked level species

Family

Family in NCBI taxonomy Aristolochiaceae
ID 16727

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy Viridiplantae
ID 33090

Plant class

Plant class Magnoliophyta
ID 3398

Metabolite list (3)

KNApSAcK ID name ChEMBL link CTD link # of proteins in
ChEMBL interaction
/ related OMIM
/ related KEGG DISEASE
# of genes in
CTD interaction
/ related diseases
KCF-S
cluster
phytochemical
cluster
figure
C00002760 External link 512 Methylisoeugenol
CHEMBL465829
CHEMBL1164609
No. 310 No. 6
C00002715 External link 512 beta-Asarone
CHEMBL333306
CHEMBL477752
2 / 1 / 1 No. 723 No. 6
C00002776 External link 512 Sinapic acid
CHEMBL109341
C073734
5 / 5 / 5 0 / 5 No. 1366 No. 6

Human Protein / Gene in interactions

7 ChEMBL Protein in interactions

accession description class description KNApSAcK metabolite in interactions # of diseases
(OMIM / KEGG)
P10635 Cytochrome P450 2D6 Cytochrome P450 2D6 C00002715 1 / 0
P35354 Prostaglandin G/H synthase 2 Oxidoreductase C00002776 0 / 3
Q13093 Platelet-activating factor acetylhydrolase Enzyme C00002776 3 / 0
P23219 Prostaglandin G/H synthase 1 Oxidoreductase C00002776 0 / 0
P17405 Sphingomyelin phosphodiesterase Enzyme C00002776 2 / 2
P08684 Cytochrome P450 3A4 Cytochrome P450 3A4 C00002715 0 / 1
O94925 Glutaminase kidney isoform, mitochondrial Enzyme C00002776 0 / 0

Related Diseases

Diseases related to proteins in ChEMBL interactions

OMIM (6)

OMIM preferred title UniProt
#600807 Asthma, susceptibility to Q13093
#608902 Drug metabolism, poor, cyp2d6-related P10635
#147050 Ige responsiveness, atopic; iger Q13093
#257200 Niemann-pick disease, type a P17405
#607616 Niemann-pick disease, type b P17405
#614278 Platelet-activating factor acetylhydrolase deficiency; pafad Q13093

KEGG DISEASE (6)

KEGG name UniProt
H00036 Osteosarcoma P08684 (marker)
H00137 Niemann-Pick disease (NPD) typeA and B P17405 (related)
H00424 Defects in the degradation of sphingomyelin P17405 (related)
H00017 Esophageal cancer P35354 (related)
H00025 Penile cancer P35354 (related)
H00046 Cholangiocarcinoma P35354 (related)

Diseases related to CTD interactions

5 disease in interactions with metabolites

MESH or OMIM name KNApSAcK
metabolite
D000647 Amnesia C00002776
D000860 Anoxia C00002776
D001930 Brain Injuries C00002776
D056486 Drug-Induced Liver Injury C00002776
D004487 Edema C00002776