Species

KNApSAcK Entry

Organism name Apium graveolens
Genus Apium
Family Apiaceae
Kingdom Plantae

NCBI taxonomy

Entry

Linked NCBI taxonomy name Apium graveolens
Linked NCBI taxonomy ID 4045
Linked level species

Family

Family in NCBI taxonomy Apiaceae
ID 4037

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy Viridiplantae
ID 33090

Plant class

Plant class asterids
ID 71274

Metabolite list (22)

KNApSAcK ID name ChEMBL link CTD link # of proteins in
ChEMBL interaction
/ related OMIM
/ related KEGG DISEASE
# of genes in
CTD interaction
/ related diseases
KCF-S
cluster
phytochemical
cluster
figure
C00001019 External link 512 Apiin
CHEMBL1077561
CHEMBL1451695
CHEMBL1535342
C012186
7 / 4 / 7 No. 1 No. 15
C00004281 External link 512 Luteolin 7-apiosyl-(1->2)-glucoside
/ Luteolin 7-O-[2-(beta-D-apiofuranosyl)-beta-D-glucopyranoside]
No. 1 No. 15
C00004342 External link 512 Graveobioside B
/ Luteolin 3'-methyl ether 7-apiosyl-(1->2)-glucoside
CHEMBL2332117
No. 1 No. 15
C00005374 External link 512 Quercetin
CHEMBL82242
CHEMBL479232
CHEMBL1437696
C012526
14 / 2 / 2 2 / 1 No. 2 No. 15
C00031677 External link 512 Chrysoeriol 7-O-glucoside
/ Chrysoeriol 7-O-beta-D-glucopyranoside
CHEMBL486391
No. 2 No. 15
C00001029 External link 512 Chrysoeriol
/ Luteolin 3'-methyl ether
CHEMBL214321
C007054
20 / 24 / 20 8 / 0 No. 3 No. 15
C00006834 External link 512 Cyanidin 3-[6-(6-sinapylglucosyl)-2-xylosylgalactoside]
No. 7 No. 15
C00006832 External link 512 Cyanidin 3-[6-(6-p-coumarylglucosyl)-2-xylosylgalactoside]
No. 7 No. 15
C00000674 External link 512 Luteolin
CHEMBL151
D047311
99 / 91 / 95 76 / 6 No. 71 No. 15
C00003817 External link 512 Apigenin
/ 5,7,4'-Trihydroxyflavone
CHEMBL28
D047310
164 / 119 / 105 68 / 8 No. 71 No. 15
C00003186 External link 512 beta-Selinene
C087920
No. 151 No. 38
C00019835 External link 512 (-)-2,3-Dihydro-9-O-beta-glucosyloxy-2-isopropenyl-7H-furo[3,2-g][1]benzopyran-7-one
No. 491 No. 25
C00019957 External link 512 5-Methoxy-8-O-beta-D-glucosyloxy-psoralen
No. 491 No. 25
C00000300 External link 512 Seselin
/ Amyrolin
/ Seseline
CHEMBL71358
2 / 0 / 0 No. 750 No. 25
C00002476 External link 512 Herniarin
/ 7-Methoxycoumarin
CHEMBL49732
C007929
23 / 10 / 12 No. 864 No. 25
C00000575 External link 512 Bergaptan
CHEMBL24171
C022909
22 / 22 / 17 0 / 3 No. 1282 No. 25
C00000576 External link 512 Xanthotoxin
CHEMBL416
D008730
104 / 55 / 45 22 / 18 No. 1282 No. 25
C00002762 External link 512 Myristicin
CHEMBL481044
C005246
6 / 4 / 2 2 / 0 No. 1917 No. 6
C00002654 External link 512 Guaiacol
/ o-Guaiacol
CHEMBL13766
D006139
15 / 18 / 47 3 / 1 No. 2352
C00019837 External link 512 (+)-2,3-Dihydro-9-hydroxy-2[1-(6-sinapinoyl)beta-D-glucosyloxy-1-methylethyl]-7H-furo[3,2-g][1]benzopyran-7-one
No. 2585
C00002502 External link 512 4,8,5'-Trimethylpsoralen
CHEMBL1475
D014307
95 / 36 / 34 0 / 5 No. 3235 No. 25
C00001193 External link 512 Malonic acid
CHEMBL7942
C030290
6 / 1 / 5 1 / 2 No. 5377

Human Protein / Gene in interactions

298 ChEMBL Protein in interactions

accession description class description KNApSAcK metabolite in interactions # of diseases
(OMIM / KEGG)
P00352 Retinal dehydrogenase 1 Enzyme C00000575 C00000674 C00001029 C00002476 C00002502 C00002762 C00003817 C00005374 0 / 0
B2RXH2 Lysine-specific demethylase 4E Enzyme C00000575 C00000674 C00001019 C00002476 C00002502 C00003817 C00005374 0 / 0
P08684 Cytochrome P450 3A4 Cytochrome P450 3A4 C00000575 C00000576 C00000674 C00002502 C00002762 C00003817 0 / 1
P33261 Cytochrome P450 2C19 Cytochrome P450 2C19 C00000575 C00000576 C00000674 C00002502 C00003817 1 / 1
P10275 Androgen receptor NR3C4 C00000575 C00000576 C00000674 C00002654 C00003817 3 / 4
P11712 Cytochrome P450 2C9 Cytochrome P450 2C9 C00000575 C00000576 C00000674 C00002502 C00003817 0 / 1
P16473 Thyrotropin receptor Glycohormone receptor C00000575 C00000576 C00000674 C00002654 C00003817 3 / 2
P56817 Beta-secretase 1 A1A C00000300 C00000575 C00000576 C00002476 C00003817 0 / 0
P05177 Cytochrome P450 1A2 Cytochrome P450 1A2 C00000576 C00000674 C00001029 C00002502 C00003817 0 / 0
O75496 Geminin Unclassified protein C00000674 C00001019 C00001029 C00002762 C00003817 0 / 0
P10635 Cytochrome P450 2D6 Cytochrome P450 2D6 C00000575 C00000576 C00000674 C00002502 C00003817 1 / 0
Q96QE3 ATPase family AAA domain-containing protein 5 Unclassified protein C00000674 C00001029 C00002502 C00002654 C00003817 0 / 0
Q9UNA4 DNA polymerase iota Enzyme C00000674 C00002762 C00003817 C00005374 0 / 0
P03956 Interstitial collagenase M10A C00000576 C00000674 C00002502 C00002654 0 / 1
Q99714 3-hydroxyacyl-CoA dehydrogenase type-2 Enzyme C00000575 C00000674 C00002476 C00003817 3 / 3
P00918 Carbonic anhydrase 2 Lyase C00000576 C00002476 C00002502 C00002654 1 / 2
O00255 Menin Unclassified protein C00000674 C00001019 C00001029 C00003817 2 / 5
P21397 Amine oxidase [flavin-containing] A Oxidoreductase C00000576 C00000674 C00002502 C00003817 1 / 1
P27695 DNA-(apurinic or apyrimidinic site) lyase Enzyme C00000674 C00002476 C00003817 C00005374 0 / 0
Q16236 Nuclear factor erythroid 2-related factor 2 Unclassified protein C00000575 C00000674 C00002654 C00003817 0 / 0
P14780 Matrix metalloproteinase-9 M10A C00000576 C00000674 C00002502 C00002654 2 / 2
P04150 Glucocorticoid receptor NR3C1 C00000576 C00000674 C00002502 C00003817 0 / 1
P35354 Prostaglandin G/H synthase 2 Oxidoreductase C00000576 C00000674 C00002502 C00003817 0 / 3
Q03164 Histone-lysine N-methyltransferase 2A Enzyme C00000674 C00001019 C00001029 C00003817 1 / 2
P23219 Prostaglandin G/H synthase 1 Oxidoreductase C00000576 C00000674 C00002502 C00003817 0 / 0
P03372 Estrogen receptor NR3A1 C00000576 C00000674 C00002502 C00003817 1 / 1
Q9UBT6 DNA polymerase kappa Enzyme C00000674 C00002476 C00003817 C00005374 0 / 0
P06239 Tyrosine-protein kinase Lck Src C00000576 C00000674 C00002502 C00003817 0 / 1
P39748 Flap endonuclease 1 Enzyme C00000674 C00001029 C00003817 C00005374 0 / 0
P22303 Acetylcholinesterase Hydrolase C00000576 C00000674 C00002502 C00003817 1 / 0
P11509 Cytochrome P450 2A6 Cytochrome P450 2A6 C00000575 C00000576 C00002502 0 / 0
O76074 cGMP-specific 3',5'-cyclic phosphodiesterase PDE_5A C00000576 C00002502 C00003817 0 / 0
P83916 Chromobox protein homolog 1 Unclassified protein C00000575 C00000576 C00002502 0 / 0
Q16539 Mitogen-activated protein kinase 14 p38 C00000576 C00002502 C00003817 0 / 0
P04637 Cellular tumor antigen p53 Transcription Factor C00000674 C00002654 C00003817 7 / 37
P33765 Adenosine receptor A3 Adenosine receptor C00000576 C00002502 C00003817 0 / 0
P35372 Mu-type opioid receptor Opioid receptor C00000576 C00002502 C00003817 0 / 0
P41145 Kappa-type opioid receptor Opioid receptor C00000576 C00002502 C00003817 0 / 0
P84022 Mothers against decapentaplegic homolog 3 Unclassified protein C00000674 C00001029 C00003817 2 / 0
P00533 Epidermal growth factor receptor TK tyrosine-protein kinase EGFR subfamily C00000576 C00002502 C00003817 1 / 8
P17252 Protein kinase C alpha type Alpha C00000576 C00002502 C00003817 0 / 0
Q9NR56 Muscleblind-like protein 1 Unclassified protein C00000674 C00001019 C00001029 1 / 0
O94782 Ubiquitin carboxyl-terminal hydrolase 1 Enzyme C00000674 C00001019 C00003817 0 / 0
P38398 Breast cancer type 1 susceptibility protein Enzyme C00000674 C00001029 C00003817 4 / 2
Q03181 Peroxisome proliferator-activated receptor delta NR1C2 C00001029 C00002762 C00003817 0 / 0
P51449 Nuclear receptor ROR-gamma Nuclear hormone receptor subfamily 1 group F member 3 C00000576 C00002654 C00003817 0 / 0
Q13526 Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 Enzyme C00000674 C00001029 C00003817 0 / 0
Q16637 Survival motor neuron protein Unclassified protein C00000674 C00002762 C00003817 4 / 1
P28482 Mitogen-activated protein kinase 1 Erk C00000576 C00002502 C00003817 0 / 0
P10636 Microtubule-associated protein tau Unclassified protein C00000674 C00001029 C00003817 4 / 3
P41143 Delta-type opioid receptor Opioid receptor C00000576 C00002502 C00003817 0 / 0
Q16678 Cytochrome P450 1B1 Cytochrome P450 1B1 C00000674 C00001029 C00003817 4 / 4
P08183 Multidrug resistance protein 1 drug C00000575 C00000674 C00003817 1 / 0
P04798 Cytochrome P450 1A1 Cytochrome P450 1A1 C00000674 C00001029 C00003817 0 / 0
Q92731 Estrogen receptor beta NR3A2 C00000576 C00002502 C00003817 0 / 1
O94925 Glutaminase kidney isoform, mitochondrial Enzyme C00000674 C00003817 C00005374 0 / 0
P47989 Xanthine dehydrogenase/oxidase Oxidoreductase C00000674 C00003817 C00005374 1 / 1
P15428 15-hydroxyprostaglandin dehydrogenase [NAD(+)] Enzyme C00000674 C00002476 C00003817 2 / 2
Q9Y253 DNA polymerase eta Enzyme C00000674 C00003817 C00005374 1 / 1
P15121 Aldose reductase Enzyme C00002476 C00005374 0 / 0
P10828 Thyroid hormone receptor beta NR1A2 C00000674 C00003817 3 / 1
P07550 Beta-2 adrenergic receptor Adrenergic receptor C00000576 C00002502 0 / 1
P02545 Prelamin-A/C Unclassified protein C00000674 C00003817 11 / 10
P25021 Histamine H2 receptor Histamine receptor C00000576 C00002502 0 / 0
P35367 Histamine H1 receptor Histamine receptor C00000576 C00002502 0 / 0
Q01959 Sodium-dependent dopamine transporter Dopamine C00000576 C00002502 1 / 0
P08912 Muscarinic acetylcholine receptor M5 Acetylcholine receptor C00000576 C00002502 0 / 0
P18825 Alpha-2C adrenergic receptor Adrenergic receptor C00000576 C00002502 0 / 0
P13945 Beta-3 adrenergic receptor Adrenergic receptor C00000576 C00002502 0 / 0
Q00534 Cyclin-dependent kinase 6 CMGC serine/threonine protein kinase family C00000674 C00003817 1 / 0
P11309 Serine/threonine-protein kinase pim-1 Pim C00000674 C00003817 0 / 0
Q15046 Lysine--tRNA ligase Enzyme C00000674 C00003817 2 / 1
O95271 Tankyrase-1 Enzyme C00000674 C00003817 0 / 0
O75164 Lysine-specific demethylase 4A Enzyme C00000674 C00005374 0 / 0
P25024 C-X-C chemokine receptor type 1 CXC chemokine receptor C00000576 C00002502 0 / 0
P24941 Cyclin-dependent kinase 2 Cdc2 C00000674 C00003817 0 / 0
P06241 Tyrosine-protein kinase Fyn Src C00000576 C00002502 0 / 0
Q08209 Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform Ser_Thr C00000576 C00002502 0 / 0
P20813 Cytochrome P450 2B6 Cytochrome P450 2B6 C00000575 C00000576 1 / 0
P23443 Ribosomal protein S6 kinase beta-1 p70 C00000576 C00003817 0 / 0
Q00535 Cyclin-dependent kinase 5 Cdk5 C00000674 C00003817 0 / 0
Q15078 Cyclin-dependent kinase 5 activator 1 REG serine/threonine protein kinase family C00000674 C00003817 0 / 0
P23975 Sodium-dependent noradrenaline transporter Norepinephrine C00000576 C00002502 1 / 1
P16050 Arachidonate 15-lipoxygenase Enzyme C00000674 C00003817 0 / 0
P33032 Melanocortin receptor 5 Melanocortin receptor C00000576 C00002502 0 / 0
P25105 Platelet-activating factor receptor PAF receptor C00000576 C00002502 0 / 0
P25103 Substance-P receptor Neurokinin receptor C00000576 C00002502 0 / 0
P27361 Mitogen-activated protein kinase 3 Erk C00000576 C00002502 0 / 0
P29466 Caspase-1 C14 C00000576 C00002502 0 / 0
P08173 Muscarinic acetylcholine receptor M4 Acetylcholine receptor C00000576 C00002502 0 / 0
P11388 DNA topoisomerase 2-alpha Isomerase C00000674 C00003817 0 / 0
P11473 Vitamin D3 receptor NR1I1 C00000576 C00003817 2 / 3
P14416 D(2) dopamine receptor Dopamine receptor C00000576 C00002502 2 / 0
P25100 Alpha-1D adrenergic receptor Adrenergic receptor C00000576 C00002502 0 / 0
P37288 Vasopressin V1a receptor Vasopressin and oxytocin receptor C00000576 C00002502 0 / 0
P30542 Adenosine receptor A1 Adenosine receptor C00000576 C00002502 0 / 0
Q9Y271 Cysteinyl leukotriene receptor 1 Leukotriene receptor C00000576 C00002502 0 / 0
P29274 Adenosine receptor A2a Adenosine receptor C00000576 C00002502 0 / 0
Q07869 Peroxisome proliferator-activated receptor alpha NR1C1 C00001029 C00003817 0 / 0
P25929 Neuropeptide Y receptor type 1 Neuropeptide Y receptor C00000576 C00002502 0 / 0
P28335 5-hydroxytryptamine receptor 2C Serotonin receptor C00000576 C00002502 0 / 0
P28223 5-hydroxytryptamine receptor 2A Serotonin receptor C00000576 C00002502 0 / 0
Q9Y3R4 Sialidase-2 Enzyme C00000674 C00003817 0 / 0
P50052 Type-2 angiotensin II receptor Angiotensin receptor C00000576 C00002502 1 / 1
P18089 Alpha-2B adrenergic receptor Adrenergic receptor C00000576 C00002502 0 / 0
P17948 Vascular endothelial growth factor receptor 1 Vegfr C00000576 C00002502 0 / 0
P41968 Melanocortin receptor 3 Melanocortin receptor C00000576 C00002502 1 / 0
P08588 Beta-1 adrenergic receptor Adrenergic receptor C00000576 C00002502 1 / 0
P24557 Thromboxane-A synthase Cytochrome P450 5A1 C00000576 C00002502 1 / 1
P04062 Glucosylceramidase Enzyme C00000674 C00003817 6 / 4
P25025 C-X-C chemokine receptor type 2 CXC chemokine receptor C00000576 C00002502 0 / 0
Q9H2K2 Tankyrase-2 Enzyme C00000674 C00003817 0 / 0
P36888 Receptor-type tyrosine-protein kinase FLT3 Pdgfr C00000674 C00003817 1 / 1
P08254 Stromelysin-1 M10A C00000674 C00002654 1 / 0
Q16665 Hypoxia-inducible factor 1-alpha Transcription Factor C00000674 C00003817 0 / 0
P49146 Neuropeptide Y receptor type 2 Neuropeptide Y receptor C00000576 C00002502 0 / 0
P06746 DNA polymerase beta Enzyme C00000674 C00001029 0 / 0
P08246 Neutrophil elastase S1A C00000576 C00002502 2 / 1
Q12809 Potassium voltage-gated channel subfamily H member 2 KCNH, Kv10-12.x (Ether-a-go-go) C00000576 C00002502 2 / 2
P27338 Amine oxidase [flavin-containing] B Oxidoreductase C00000674 C00003817 0 / 0
P21728 D(1A) dopamine receptor Dopamine receptor C00000576 C00002502 0 / 0
P04035 3-hydroxy-3-methylglutaryl-coenzyme A reductase Oxidoreductase C00000576 C00002502 0 / 0
P08913 Alpha-2A adrenergic receptor Adrenergic receptor C00000576 C00002502 0 / 0
P21917 D(4) dopamine receptor Dopamine receptor C00000576 C00002502 0 / 0
P30988 Calcitonin receptor Calcitonin receptor C00000576 C00002502 0 / 0
P35462 D(3) dopamine receptor Dopamine receptor C00000576 C00002502 1 / 0
Q96KQ7 Histone-lysine N-methyltransferase EHMT2 Enzyme C00000674 C00002654 0 / 0
Q9NUW8 Tyrosyl-DNA phosphodiesterase 1 Enzyme C00000674 C00003817 1 / 1
P41595 5-hydroxytryptamine receptor 2B Serotonin receptor C00000576 C00002502 0 / 0
P05181 Cytochrome P450 2E1 Cytochrome P450 2E1 C00000576 C00002502 0 / 0
P25101 Endothelin-1 receptor Endothelin receptor C00000576 C00002502 0 / 0
P30411 B2 bradykinin receptor Bradykinin receptor C00000576 C00002502 0 / 0
Q99700 Ataxin-2 Unclassified protein C00000674 C00003817 1 / 1
P32245 Melanocortin receptor 4 Melanocortin receptor C00000576 C00002502 1 / 0
P00915 Carbonic anhydrase 1 Lyase C00002476 C00002654 0 / 0
P49841 Glycogen synthase kinase-3 beta Gsk C00000674 C00003817 0 / 0
P32238 Cholecystokinin receptor type A Cholecystokinin receptor C00000576 C00002502 0 / 0
P08311 Cathepsin G S1A C00000576 C00002502 0 / 0
Q92887 Canalicular multispecific organic anion transporter 1 Unclassified protein C00001029 C00003817 1 / 1
Q9UNQ0 ATP-binding cassette sub-family G member 2 ATP binding cassette C00000674 C00003817 2 / 0
Q99720 Sigma non-opioid intracellular receptor 1 Membrane receptor C00000576 C00002502 1 / 0
P09874 Poly [ADP-ribose] polymerase 1 Enzyme C00000674 C00003817 0 / 0
P43220 Glucagon-like peptide 1 receptor Glucagon-like peptide receptor C00000576 C00002502 0 / 0
Q13951 Core-binding factor subunit beta Unclassified protein C00000674 C00003817 0 / 1
Q01196 Runt-related transcription factor 1 Unclassified protein C00000674 C00003817 1 / 4
P32241 Vasoactive intestinal polypeptide receptor 1 Vasoactive intestinal peptide receptor C00000576 C00002502 0 / 0
P08253 72 kDa type IV collagenase M10A C00000674 C00002654 1 / 3
P63092 Guanine nucleotide-binding protein G(s) subunit alpha isoforms short Other membrane protein C00000575 C00000576 7 / 3
Q9UIF8 Bromodomain adjacent to zinc finger domain protein 2B Unclassified protein C00000674 C00001019 0 / 0
O95067 G2/mitotic-specific cyclin-B2 Other cytosolic protein C00000674 C00003817 0 / 0
Q9NPH5 NADPH oxidase 4 Enzyme C00000674 C00003817 0 / 0
P14635 G2/mitotic-specific cyclin-B1 Other cytosolic protein C00000674 C00003817 0 / 0
P06493 Cyclin-dependent kinase 1 Cdc2 C00000674 C00003817 0 / 0
P11021 78 kDa glucose-regulated protein Unclassified protein C00000674 C00003817 0 / 0
Q8WWL7 G2/mitotic-specific cyclin-B3 Other cytosolic protein C00000674 C00003817 0 / 0
Q09470 Potassium voltage-gated channel subfamily A member 1 KCNA, Kv1.x (Shaker) C00000575 C00000576 1 / 1
P08172 Muscarinic acetylcholine receptor M2 Acetylcholine receptor C00000576 C00002502 2 / 0
P11229 Muscarinic acetylcholine receptor M1 Acetylcholine receptor C00000576 C00002502 0 / 0
P08575 Receptor-type tyrosine-protein phosphatase C Enzyme C00000576 C00002502 2 / 1
P33527 Multidrug resistance-associated protein 1 drugs C00001029 C00003817 0 / 0
P21554 Cannabinoid receptor 1 Cannabinoid receptor C00000576 C00002502 0 / 0
P31645 Sodium-dependent serotonin transporter Serotonin C00000576 C00002502 2 / 0
P37231 Peroxisome proliferator-activated receptor gamma NR1C3 C00001029 C00003817 5 / 3
P04626 Receptor tyrosine-protein kinase erbB-2 TK tyrosine-protein kinase EGFR subfamily C00000576 C00002502 5 / 9
P20309 Muscarinic acetylcholine receptor M3 Acetylcholine receptor C00000576 C00002502 1 / 0
P41597 C-C chemokine receptor type 2 CC chemokine receptor C00000576 C00002502 1 / 0
P49840 Glycogen synthase kinase-3 alpha Gsk C00000674 C00003817 0 / 0
P21452 Substance-K receptor Neurokinin receptor C00000576 C00002502 0 / 0
P50406 5-hydroxytryptamine receptor 6 Serotonin receptor C00000576 C00002502 0 / 0
P06276 Cholinesterase Hydrolase C00000674 C00003817 0 / 0
P51679 C-C chemokine receptor type 4 CC chemokine receptor C00000576 C00002502 0 / 0
P51681 C-C chemokine receptor type 5 CC chemokine receptor C00000576 C00002502 3 / 0
Q9Y468 Lethal(3)malignant brain tumor-like protein 1 Unclassified protein C00005374 0 / 0
P06280 Alpha-galactosidase A Enzyme C00000674 1 / 1
P04745 Alpha-amylase 1 Enzyme C00000674 0 / 0
P45452 Collagenase 3 M10A C00000674 1 / 1
P49137 MAP kinase-activated protein kinase 2 CAMK serine/threonine protein kinase MAPKAPK C00003817 0 / 0
P18054 Arachidonate 12-lipoxygenase, 12S-type Enzyme C00000674 2 / 0
Q96RI1 Bile acid receptor NR1H4 C00003817 0 / 0
P00338 L-lactate dehydrogenase A chain Enzyme C00001193 1 / 5
P14679 Tyrosinase Oxidoreductase C00000674 4 / 2
P11511 Cytochrome P450 19A1 Cytochrome P450 19A1 C00003817 2 / 2
Q9NPD5 Solute carrier organic anion transporter family member 1B3 Electrochemical transporter C00000576 1 / 0
P12931 Proto-oncogene tyrosine-protein kinase Src Src C00001193 0 / 0
Q16790 Carbonic anhydrase 9 Lyase C00002476 0 / 1
Q9GZT4 Serine racemase Enzyme C00001193 0 / 0
Q9Y4K4 Mitogen-activated protein kinase kinase kinase kinase 5 STE serine/threonine protein kinase KHS subfamily C00003817 0 / 0
Q12791 Calcium-activated potassium channel subunit alpha-1 KCNM, KCa1.x C00003817 1 / 1
O15264 Mitogen-activated protein kinase 13 p38 C00003817 0 / 0
Q15418 Ribosomal protein S6 kinase alpha-1 Rskb C00003817 0 / 0
P10145 Interleukin-8 Secreted protein C00003817 0 / 0
O15118 Niemann-Pick C1 protein Unclassified protein C00003817 1 / 1
Q01453 Peripheral myelin protein 22 Unclassified protein C00003817 5 / 2
P54855 UDP-glucuronosyltransferase 2B15 Enzyme C00003817 0 / 0
P09769 Tyrosine-protein kinase Fgr Src C00003817 0 / 0
Q9HAW9 UDP-glucuronosyltransferase 1-8 Enzyme C00003817 0 / 0
O43570 Carbonic anhydrase 12 Lyase C00002476 1 / 2
O14763 Tumor necrosis factor receptor superfamily member 10B Unclassified protein C00000674 1 / 0
P68871 Hemoglobin subunit beta Secreted protein C00003817 4 / 4
P28845 Corticosteroid 11-beta-dehydrogenase isozyme 1 Enzyme C00002476 1 / 1
Q9ULX7 Carbonic anhydrase 14 Lyase C00002476 0 / 0
O15296 Arachidonate 15-lipoxygenase B Enzyme C00000674 0 / 0
P16389 Potassium voltage-gated channel subfamily A member 2 KCNA, Kv1.x (Shaker) C00000575 0 / 0
O75582 Ribosomal protein S6 kinase alpha-5 CAMK serine/threonine protein kinase MSKB subfamily C00003817 0 / 0
P23280 Carbonic anhydrase 6 Lyase C00002476 0 / 0
P11387 DNA topoisomerase 1 Isomerase C00000674 0 / 0
Q9HC97 G-protein coupled receptor 35 Kynurenic acid receptor C00000674 0 / 0
P51570 Galactokinase Enzyme C00000674 1 / 1
P54132 Bloom syndrome protein Enzyme C00000674 1 / 2
Q8IW41 MAP kinase-activated protein kinase 5 CAMK serine/threonine protein kinase MAPKAPK C00003817 0 / 0
O75116 Rho-associated protein kinase 2 Rock C00003817 0 / 0
Q00796 Sorbitol dehydrogenase Enzyme C00002476 0 / 0
P19838 Nuclear factor NF-kappa-B p105 subunit Transcription Factor C00003817 0 / 0
P07948 Tyrosine-protein kinase Lyn Src C00003817 0 / 0
Q02880 DNA topoisomerase 2-beta Isomerase C00003817 0 / 0
P14920 D-amino-acid oxidase Enzyme C00001193 0 / 0
P31749 RAC-alpha serine/threonine-protein kinase Akt C00003817 4 / 1
O00141 Serine/threonine-protein kinase Sgk1 AGC serine/threonine protein kinase SGK subfamily C00003817 0 / 0
P07237 Protein disulfide-isomerase Enzyme C00005374 0 / 0
P37059 Estradiol 17-beta-dehydrogenase 2 Enzyme C00003817 0 / 0
P49327 Fatty acid synthase Transferase C00000674 0 / 0
P68400 Casein kinase II subunit alpha Ck2 C00003817 0 / 0
P19793 Retinoic acid receptor RXR-alpha NR2B1 C00003817 0 / 0
O75604 Ubiquitin carboxyl-terminal hydrolase 2 Enzyme C00003817 0 / 0
Q6W5P4 Neuropeptide S receptor Neuropeptide receptor C00003817 1 / 0
Q99489 D-aspartate oxidase Enzyme C00001193 0 / 0
P17658 Potassium voltage-gated channel subfamily A member 6 K C00000575 0 / 0
P22309 UDP-glucuronosyltransferase 1-1 Enzyme C00003817 5 / 1
P28907 ADP-ribosyl cyclase 1 Enzyme C00000674 0 / 1
Q99549 M-phase phosphoprotein 8 Unclassified protein C00003817 0 / 0
O14757 Serine/threonine-protein kinase Chk1 Chk1 C00003817 0 / 0
P39900 Macrophage metalloelastase M10A C00000674 0 / 0
P04406 Glyceraldehyde-3-phosphate dehydrogenase Enzyme C00000300 0 / 0
P22894 Neutrophil collagenase M10A C00002654 0 / 0
P43166 Carbonic anhydrase 7 Lyase C00002476 0 / 0
P35218 Carbonic anhydrase 5A, mitochondrial Lyase C00002476 0 / 0
Q9Y2D0 Carbonic anhydrase 5B, mitochondrial Lyase C00002476 0 / 0
P10253 Lysosomal alpha-glucosidase Hydrolase C00000674 1 / 1
P07451 Carbonic anhydrase 3 Lyase C00002476 0 / 0
P41240 Tyrosine-protein kinase CSK Csk C00003817 0 / 0
P22460 Potassium voltage-gated channel subfamily A member 5 KCNA, Kv1.x (Shaker) C00000575 1 / 1
Q04760 Lactoylglutathione lyase Enzyme C00000674 0 / 0
P54646 5'-AMP-activated protein kinase catalytic subunit alpha-2 Ampk C00003817 0 / 0
P35869 Aryl hydrocarbon receptor Transcription Factor C00003817 0 / 0
O15530 3-phosphoinositide-dependent protein kinase 1 Pdk1 C00003817 0 / 0
P43405 Tyrosine-protein kinase SYK Syk C00003817 0 / 0
P22001 Potassium voltage-gated channel subfamily A member 3 KCNA, Kv1.x (Shaker) C00000575 0 / 0
Q13627 Dual specificity tyrosine-phosphorylation-regulated kinase 1A CMGC dual-specificity kinase DYRK1 C00003817 1 / 0
P22748 Carbonic anhydrase 4 Lyase C00002476 1 / 1
P53778 Mitogen-activated protein kinase 12 p38 C00003817 0 / 0
P80365 Corticosteroid 11-beta-dehydrogenase isozyme 2 Enzyme C00002476 1 / 1
Q15759 Mitogen-activated protein kinase 11 p38 C00003817 0 / 0
O14980 Exportin-1 Unclassified protein C00002476 0 / 0
P09917 Arachidonate 5-lipoxygenase Oxidoreductase C00002654 0 / 0
P46063 ATP-dependent DNA helicase Q1 Enzyme C00000674 0 / 0
P40225 Thrombopoietin Unclassified protein C00003817 1 / 1
P14618 Pyruvate kinase PKM Enzyme C00003817 0 / 0
Q16798 NADP-dependent malic enzyme, mitochondrial Enzyme C00001193 0 / 0
O75874 Isocitrate dehydrogenase [NADP] cytoplasmic Enzyme C00003817 1 / 0
P49798 Regulator of G-protein signaling 4 Unclassified protein C00003817 2 / 0
Q9HAW8 UDP-glucuronosyltransferase 1-10 Enzyme C00003817 0 / 0
O94956 Solute carrier organic anion transporter family member 2B1 Unclassified protein C00000576 0 / 0
Q9UN88 Gamma-aminobutyric acid receptor subunit theta GABA-A theta C00003817 0 / 0
P28472 Gamma-aminobutyric acid receptor subunit beta-3 GABA-A beta C00003817 1 / 0
P14867 Gamma-aminobutyric acid receptor subunit alpha-1 GABA-A alpha C00003817 1 / 1
P48169 Gamma-aminobutyric acid receptor subunit alpha-4 GABA-A alpha C00003817 0 / 0
O14764 Gamma-aminobutyric acid receptor subunit delta GABA-A delta C00003817 1 / 1
P31644 Gamma-aminobutyric acid receptor subunit alpha-5 GABA-A alpha C00003817 0 / 0
Q99928 Gamma-aminobutyric acid receptor subunit gamma-3 GABA-A gamma C00003817 0 / 0
P78334 Gamma-aminobutyric acid receptor subunit epsilon GABA-A epsilon C00003817 0 / 0
Q8N1C3 Gamma-aminobutyric acid receptor subunit gamma-1 GABA-A gamma C00003817 0 / 0
P34903 Gamma-aminobutyric acid receptor subunit alpha-3 GABA-A alpha C00003817 0 / 0
O00591 Gamma-aminobutyric acid receptor subunit pi GABA-A pi C00003817 0 / 0
P47870 Gamma-aminobutyric acid receptor subunit beta-2 GABA-A beta C00003817 0 / 0
P18507 Gamma-aminobutyric acid receptor subunit gamma-2 GABA-A gamma C00003817 4 / 2
P18505 Gamma-aminobutyric acid receptor subunit beta-1 GABA-A beta C00003817 0 / 0
Q16445 Gamma-aminobutyric acid receptor subunit alpha-6 GABA-A alpha C00003817 0 / 0
P47869 Gamma-aminobutyric acid receptor subunit alpha-2 GABA-A alpha C00003817 1 / 0
P45983 Mitogen-activated protein kinase 8 Jnk C00003817 0 / 0
P53779 Mitogen-activated protein kinase 10 Jnk C00003817 0 / 1
P45984 Mitogen-activated protein kinase 9 Jnk C00003817 0 / 0
Q9Y6L6 Solute carrier organic anion transporter family member 1B1 Electrochemical transporter C00000576 1 / 0
P48547 Potassium voltage-gated channel subfamily C member 1 K C00000575 0 / 0
Q9P1W9 Serine/threonine-protein kinase pim-2 Pim C00005374 0 / 0
P22310 UDP-glucuronosyltransferase 1-4 Enzyme C00003817 3 / 0
P22694 cAMP-dependent protein kinase catalytic subunit beta Pka C00003817 0 / 0
P17612 cAMP-dependent protein kinase catalytic subunit alpha Pka C00003817 0 / 0
P22612 cAMP-dependent protein kinase catalytic subunit gamma Pka C00003817 0 / 0
P14061 Estradiol 17-beta-dehydrogenase 1 Enzyme C00003817 0 / 0
Q9HCP0 Casein kinase I isoform gamma-1 Ck1 C00003817 0 / 0
P48730 Casein kinase I isoform delta Ck1 C00003817 1 / 0
P49674 Casein kinase I isoform epsilon Ck1 C00003817 0 / 0
P78368 Casein kinase I isoform gamma-2 Ck1 C00003817 0 / 0
P48729 Casein kinase I isoform alpha Ck1 C00003817 0 / 0
Q02750 Dual specificity mitogen-activated protein kinase kinase 1 Ste7 C00003817 1 / 1
P01215 Glycoprotein hormones alpha chain Unclassified protein C00002502 0 / 3
Q14191 Werner syndrome ATP-dependent helicase Enzyme C00000674 2 / 1
Q13148 TAR DNA-binding protein 43 Unclassified protein C00000576 1 / 1

120 Gene in CTD interactions

gene gene name gene description KNApSAcK metabolite in interactions
1543 CYP1A1, AHH, AHRR, CP11, CYP1, P1-450, P450-C, P450DX cytochrome P450, family 1, subfamily A, polypeptide 1 (EC:1.14.14.1) C00000576 C00000674 C00001029 C00003817
C00005374
1576 CYP3A4, CP33, CP34, CYP3A, CYP3A3, CYPIIIA3, CYPIIIA4, HLP, NF-25, P450C3, P450PCN1 cytochrome P450, family 3, subfamily A, polypeptide 4 (EC:1.14.13.67 1.14.13.97 1.14.13.32 1.14.13.157) C00000576 C00000674 C00002762 C00003817
1544 CYP1A2, CP12, P3-450, P450(PA) cytochrome P450, family 1, subfamily A, polypeptide 2 (EC:1.14.14.1) C00000576 C00001029 C00002762 C00003817
1545 CYP1B1, CP1B, CYPIB1, GLC3A, P4501B1 cytochrome P450, family 1, subfamily B, polypeptide 1 (EC:1.14.14.1) C00000674 C00001029 C00003817 C00005374
196 AHR, bHLHe76 aryl hydrocarbon receptor C00000674 C00001029 C00003817
4363 ABCC1, ABC29, ABCC, GS-X, MRP, MRP1 ATP-binding cassette, sub-family C (CFTR/MRP), member 1 C00000674 C00001029 C00003817
7124 TNF, DIF, TNF-alpha, TNFA, TNFSF2 tumor necrosis factor C00000576 C00000674 C00003817
842 CASP9, APAF-3, APAF3, ICE-LAP6, MCH6, PPP1R56 caspase 9, apoptosis-related cysteine peptidase (EC:3.4.22.62) C00000576 C00000674 C00003817
841 CASP8, ALPS2B, CAP4, Casp-8, FLICE, MACH, MCH5 caspase 8, apoptosis-related cysteine peptidase (EC:3.4.22.61) C00000576 C00000674 C00003817
836 CASP3, CPP32, CPP32B, SCA-1 caspase 3, apoptosis-related cysteine peptidase (EC:3.4.22.56) C00000576 C00000674 C00003817
596 BCL2, Bcl-2, PPP1R50 B-cell CLL/lymphoma 2 C00000576 C00000674 C00003817
4793 NFKBIB, IKBB, TRIP9 nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta C00000674 C00003817
9540 TP53I3, PIG3 tumor protein p53 inducible protein 3 C00000674 C00003817
581 BAX, BCL2L4 BCL2-associated X protein C00000576 C00000674
7161 TP73, P73 tumor protein p73 C00000674 C00003817
6401 SELE, CD62E, ELAM, ELAM1, ESEL, LECAM2 selectin E C00000674 C00003817
5970 RELA, NFKB3, p65 v-rel avian reticuloendotheliosis viral oncogene homolog A C00000674 C00003817
54658 UGT1A1, BILIQTL1, GNT1, HUG-BR1, UDPGT, UDPGT_1-1, UGT1, UGT1A UDP glucuronosyltransferase 1 family, polypeptide A1 (EC:2.4.1.17) C00000674 C00003817
7412 VCAM1, CD106, INCAM-100 vascular cell adhesion molecule 1 C00000674 C00003817
7422 VEGFA, MVCD1, VEGF, VPF vascular endothelial growth factor A C00000674 C00003817
1027 CDKN1B, CDKN4, KIP1, MEN1B, MEN4, P27KIP1 cyclin-dependent kinase inhibitor 1B (p27, Kip1) C00000576 C00000674
8000 PSCA, PRO232 prostate stem cell antigen C00000674 C00003817
8626 TP63, AIS, B(p51A), B(p51B), EEC3, KET, LMS, NBP, OFC8, RHS, SHFM4, TP53CP, TP53L, TP73L, p40, p51, p53CP, p63, p73H, p73L tumor protein p63 C00000674 C00003817
4792 NFKBIA, IKBA, MAD-3, NFKBI nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha C00000674 C00003817
1559 CYP2C9, CPC9, CYP2C, CYP2C10, CYPIIC9, P450IIC9 cytochrome P450, family 2, subfamily C, polypeptide 9 (EC:1.14.13.48 1.14.13.49 1.14.13.80) C00000576 C00003817
4318 MMP9, CLG4B, GELB, MANDP2, MMP-9 matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase) (EC:3.4.24.35) C00000674 C00003817
4312 MMP1, CLG, CLGN matrix metallopeptidase 1 (interstitial collagenase) (EC:3.4.24.7) C00000674 C00003817
5595 MAPK3, ERK-1, ERK1, ERT2, HS44KDAP, HUMKER1A, P44ERK1, P44MAPK, PRKM3, p44-ERK1, p44-MAPK mitogen-activated protein kinase 3 (EC:2.7.11.24) C00000674 C00003817
2099 ESR1, ER, ESR, ESRA, ESTRR, Era, NR3A1 estrogen receptor 1 C00000674 C00003817
3725 JUN, AP-1, AP1, c-Jun jun proto-oncogene C00000674 C00003817
8839 WISP2, CCN5, CT58, CTGF-L WNT1 inducible signaling pathway protein 2 C00000674 C00003817
7157 TP53, BCC7, LFS1, P53, TRP53 tumor protein p53 C00000576 C00003817
207 AKT1, AKT, CWS6, PKB, PKB-ALPHA, PRKBA, RAC, RAC-ALPHA v-akt murine thymoma viral oncogene homolog 1 (EC:2.7.11.1) C00000674 C00003817
3565 IL4, BCGF-1, BCGF1, BSF-1, BSF1, IL-4 interleukin 4 C00000674 C00003817
3383 ICAM1, BB2, CD54, P3.58 intercellular adhesion molecule 1 C00000674 C00003817
840 CASP7, CASP-7, CMH-1, ICE-LAP3, LICE2, MCH3 caspase 7, apoptosis-related cysteine peptidase (EC:3.4.22.60) C00000674 C00003817
847 CAT catalase (EC:1.11.1.6) C00000674 C00003817
891 CCNB1, CCNB cyclin B1 C00000674 C00003817
958 CD40, Bp50, CDW40, TNFRSF5, p50 CD40 molecule, TNF receptor superfamily member 5 C00000674 C00003817
983 CDK1, CDC2, CDC28A, P34CDC2 cyclin-dependent kinase 1 (EC:2.7.11.23 2.7.11.22) C00000674 C00003817
1026 CDKN1A, CAP20, CDKN1, CIP1, MDA-6, P21, SDI1, WAF1, p21CIP1 cyclin-dependent kinase inhibitor 1A (p21, Cip1) C00000674 C00003817
1031 CDKN2C, INK4C, p18, p18-INK4C cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4) C00000674 C00003817
2353 FOS, AP-1, C-FOS, p55 FBJ murine osteosarcoma viral oncogene homolog C00000674 C00003817
2203 FBP1, FBP fructose-1,6-bisphosphatase 1 (EC:3.1.3.11) C00000674 C00003817
2100 ESR2, ER-BETA, ESR-BETA, ESRB, ESTRB, Erb, NR3A2 estrogen receptor 2 (ER beta) C00000674 C00003817
5594 MAPK1, ERK, ERK2, ERT1, MAPK2, P42MAPK, PRKM1, PRKM2, p38, p40, p41, p41mapk mitogen-activated protein kinase 1 (EC:2.7.11.24) C00000674 C00003817
1586 CYP17A1, CPT7, CYP17, P450C17, S17AH cytochrome P450, family 17, subfamily A, polypeptide 1 (EC:1.14.99.9 4.1.2.30) C00003817
1588 CYP19A1, ARO, ARO1, CPV1, CYAR, CYP19, CYPXIX, P-450AROM cytochrome P450, family 19, subfamily A, polypeptide 1 (EC:1.14.14.1) C00003817
1589 CYP21A2, CA21H, CAH1, CPS1, CYP21, CYP21B, P450c21B cytochrome P450, family 21, subfamily A, polypeptide 2 (EC:1.14.99.10) C00003817
2064 ERBB2, CD340, HER-2, HER-2/neu, HER2, MLN_19, NEU, NGL, TKR1 v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 2 (EC:2.7.10.1) C00003817
1584 CYP11B1, CPN1, CYP11B, FHI, P450C11 cytochrome P450, family 11, subfamily B, polypeptide 1 (EC:1.14.15.4) C00003817
54205 CYCS, CYC, HCS, THC4 cytochrome c, somatic C00003817
6387 CXCL12, IRH, PBSF, SCYB12, SDF1, TLSF, TPAR1, SDF1A, SDF1B chemokine (C-X-C motif) ligand 12 C00003817
1080 CFTR, ABC35, ABCC7, CF, CFTR/MRP, MRP7, TNR-CFTR, dJ760C5.1 cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7) (EC:3.6.3.49) C00003817
2729 GCLC, GCL, GCS, GLCL, GLCLC glutamate-cysteine ligase, catalytic subunit (EC:6.3.2.2) C00003817
3091 HIF1A, HIF-1A, HIF-1alpha, HIF1, HIF1-ALPHA, MOP1, PASD8, bHLHe78 hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) C00003817
3284 HSD3B2, HSD3B, HSDB, SDR11E2 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2 (EC:1.1.1.145 5.3.3.1) C00003817
330 BIRC3, AIP1, API2, CIAP2, HAIP1, HIAP1, MALT2, MIHC, RNF49, c-IAP2 baculoviral IAP repeat containing 3 C00003817
405 ARNT, HIF-1-beta, HIF-1beta, HIF1-beta, HIF1B, HIF1BETA, TANGO, bHLHe2 aryl hydrocarbon receptor nuclear translocator C00003817
5925 RB1, OSRC, RB, p105-Rb, pRb, pp110 retinoblastoma 1 C00000576
3355109 C00000576
8856 NR1I2, BXR, ONR1, PAR, PAR1, PAR2, PARq, PRR, PXR, SAR, SXR nuclear receptor subfamily 1, group I, member 2 C00000576
3034 HAL, HIS, HSTD histidine ammonia-lyase (EC:4.3.1.3) C00000576
1565 CYP2D6, CPD6, CYP2D, CYP2D7AP, CYP2D7BP, CYP2D7P2, CYP2D8P2, CYP2DL1, CYPIID6, P450-DB1, P450C2D, P450DB1 cytochrome P450, family 2, subfamily D, polypeptide 6 (EC:1.14.14.1) C00000576
1548 CYP2A6, CPA6, CYP2A, CYP2A3, CYPIIA6, P450C2A, P450PB cytochrome P450, family 2, subfamily A, polypeptide 6 (EC:1.14.14.1) C00000576
1553 CYP2A13, CPAD, CYP2A, CYPIIA13 cytochrome P450, family 2, subfamily A, polypeptide 13 (EC:1.14.14.1) C00000576
5241 PGR, NR3C3, PR progesterone receptor C00003817
5562 PRKAA1, AMPK, AMPKa1 protein kinase, AMP-activated, alpha 1 catalytic subunit (EC:2.7.11.1 2.7.11.26 2.7.11.27 2.7.11.31) C00003817
8824 CES2, CE-2, CES2A1, PCE-2, iCE carboxylesterase 2 (EC:3.1.1.1 3.1.1.84 3.1.1.56) C00000576
332 BIRC5, API4, EPR-1 baculoviral IAP repeat containing 5 C00000576
6198 RPS6KB1, PS6K, S6K, S6K-beta-1, S6K1, STK14A, p70_S6KA, p70(S6K)-alpha, p70-S6K, p70-alpha ribosomal protein S6 kinase, 70kDa, polypeptide 1 (EC:2.7.11.1) C00003817
8553 BHLHE40, BHLHB2, DEC1, HLHB2, SHARP-2, STRA13, Stra14 basic helix-loop-helix family, member e40 C00000576
6817 SULT1A1, HAST1/HAST2, P-PST, PST, ST1A1, ST1A3, STP, STP1, TSPST1 sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1 (EC:2.8.2.1) C00003817
6783 SULT1E1, EST, EST-1, ST1E1, STE sulfotransferase family 1E, estrogen-preferring, member 1 (EC:2.8.2.4) C00003817
760 CA2, CA-II, CAC, CAII, Car2 carbonic anhydrase II (EC:4.2.1.1) C00002654
759 CA1, CA-I, CAB, Car1 carbonic anhydrase I (EC:4.2.1.1) C00002654
213 ALB, PRO0883, PRO0903, PRO1341 albumin C00002654
10891 PPARGC1A, LEM6, PGC-1(alpha), PGC-1v, PGC1, PGC1A, PPARGC1 peroxisome proliferator-activated receptor gamma, coactivator 1 alpha C00001193
54575 UGT1A10, UDPGT, UGT-1J, UGT1-10, UGT1.10, UGT1J UDP glucuronosyltransferase 1 family, polypeptide A10 (EC:2.4.1.17) C00003817
54577 UGT1A7, UDPGT, UDPGT_1-7, UGT-1G, UGT1-07, UGT1.7, UGT1G UDP glucuronosyltransferase 1 family, polypeptide A7 (EC:2.4.1.17) C00003817
54576 UGT1A8, UDPGT, UDPGT_1-8, UGT-1H, UGT1-08, UGT1.8, UGT1A8S, UGT1H UDP glucuronosyltransferase 1 family, polypeptide A8 (EC:2.4.1.17) C00003817
54600 UGT1A9, HLUGP4, LUGP4, UDPGT, UDPGT_1-9, UGT-1I, UGT1-09, UGT1-9, UGT1.9, UGT1AI, UGT1I UDP glucuronosyltransferase 1 family, polypeptide A9 (EC:2.4.1.17) C00003817
7366 UGT2B15, HLUG4, UDPGT_2B8, UDPGT2B15, UDPGTH3, UGT2B8 UDP glucuronosyltransferase 2 family, polypeptide B15 (EC:2.4.1.17) C00003817
7402 UTRN, DMDL, DRP, DRP1 utrophin C00003817
4835 NQO2, DHQV, DIA6, NMOR2, QR2 NAD(P)H dehydrogenase, quinone 2 (EC:1.10.99.2) C00001029
4544 MTNR1B, FGQTL2, MEL-1B-R, MT2 melatonin receptor 1B C00001029
4543 MTNR1A, MEL-1A-R, MT1 melatonin receptor 1A C00001029
9429 ABCG2, ABC15, ABCP, BCRP, BCRP1, BMDP, CD338, CDw338, EST157481, GOUT1, MRX, MXR, MXR1, UAQTL1 ATP-binding cassette, sub-family G (WHITE), member 2 C00000674
177 AGER, RAGE advanced glycosylation end product-specific receptor C00000674
598 BCL2L1, BCL-XL/S, BCL2L, BCLX, BCLXL, BCLXS, Bcl-X, PPP1R52, bcl-xL, bcl-xS BCL2-like 1 C00000674
329 BIRC2, API1, HIAP2, Hiap-2, MIHB, RNF48, c-IAP1, cIAP1 baculoviral IAP repeat containing 2 C00000674
890 CCNA2, CCN1, CCNA cyclin A2 C00000674
972 CD74, DHLAG, HLADG, II, Ia-GAMMA CD74 molecule, major histocompatibility complex, class II invariant chain C00000674
1017 CDK2, p33(CDK2) cyclin-dependent kinase 2 (EC:2.7.11.22) C00000674
1437 CSF2, GMCSF colony stimulating factor 2 (granulocyte-macrophage) C00000674
1577 CYP3A5, CP35, CYPIIIA5, P450PCN3, PCN3 cytochrome P450, family 3, subfamily A, polypeptide 5 (EC:1.14.14.1) C00000674
1950 EGF, HOMG4, URG epidermal growth factor C00000674
1956 EGFR, ERBB, ERBB1, HER1, PIG61, mENA epidermal growth factor receptor (EC:2.7.10.1) C00000674
1958 EGR1, AT225, G0S30, KROX-24, NGFI-A, TIS8, ZIF-268, ZNF225 early growth response 1 C00000674
2354 FOSB, AP-1, G0S3, GOS3, GOSB FBJ murine osteosarcoma viral oncogene homolog B C00000674
4616 GADD45B, GADD45BETA, MYD118 growth arrest and DNA-damage-inducible, beta C00000674
3553 IL1B, IL-1, IL1-BETA, IL1F2 interleukin 1, beta C00000674
3726 JUNB, AP-1 jun B proto-oncogene C00000674
3727 JUND, AP-1 jun D proto-oncogene C00000674
5602 MAPK10, JNK3, JNK3A, PRKM10, SAPK1b, p493F12, p54bSAPK mitogen-activated protein kinase 10 (EC:2.7.11.24) C00000674
5599 MAPK8, JNK, JNK-46, JNK1, JNK1A2, JNK21B1/2, PRKM8, SAPK1, SAPK1c mitogen-activated protein kinase 8 (EC:2.7.11.24) C00000674
5601 MAPK9, JNK-55, JNK2, JNK2A, JNK2ALPHA, JNK2B, JNK2BETA, PRKM9, SAPK, SAPK1a, p54a, p54aSAPK mitogen-activated protein kinase 9 (EC:2.7.11.24) C00000674
4790 NFKB1, EBP-1, KBF1, NF-kB1, NF-kappa-B, NF-kappaB, NFKB-p105, NFKB-p50, NFkappaB, p105, p50 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 C00000674
9572 NR1D1, EAR1, THRA1, THRAL, ear-1, hRev nuclear receptor subfamily 1, group D, member 1 C00000674
5347 PLK1, PLK, STPK13 polo-like kinase 1 (EC:2.7.11.21) C00000674
5743 PTGS2, COX-2, COX2, GRIPGHS, PGG/HS, PGHS-2, PHS-2, hCox-2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) (EC:1.14.99.1) C00000674
5747 PTK2, FADK, FAK, FAK1, FRNK, PPP1R71, p125FAK, pp125FAK protein tyrosine kinase 2 (EC:2.7.10.2) C00000674
2810 SFN, YWHAS stratifin C00000674
6647 SOD1, ALS, ALS1, IPOA, SOD, hSod1, homodimer superoxide dismutase 1, soluble (EC:1.15.1.1) C00000674
29110 TBK1, NAK, T2K TANK-binding kinase 1 (EC:2.7.11.1) C00000674
7128 TNFAIP3, A20, OTUD7C, TNFA1P2 tumor necrosis factor, alpha-induced protein 3 (EC:3.4.19.12) C00000674
8743 TNFSF10, APO2L, Apo-2L, CD253, TL2, TRAIL tumor necrosis factor (ligand) superfamily, member 10 C00000674
54659 UGT1A3, UDPGT, UDPGT_1-3, UGT-1C, UGT1-03, UGT1.3, UGT1C UDP glucuronosyltransferase 1 family, polypeptide A3 (EC:2.4.1.17) C00000674
10451 VAV3 vav 3 guanine nucleotide exchange factor C00000674
331 XIAP, API3, BIRC4, IAP-3, ILP1, MIHA, XLP2, hIAP-3, hIAP3 X-linked inhibitor of apoptosis C00000674

Related Diseases

Diseases related to proteins in ChEMBL interactions

OMIM (175)

OMIM preferred title UniProt
#300438 17-beta-hydroxysteroid dehydrogenase x deficiency Q99714
#100100 Abdominal muscles, absence of, with urinary tract abnormality and cryptorchidism P20309
#219080 Acth-independent macronodular adrenal hyperplasia; aimah P63092
#202300 Adrenocortical carcinoma, hereditary; adcc P04637
#615224 Advanced sleep phase syndrome, familial, 2; fasps2 P48730
#103470 Albinism, ocular, with sensorineural deafness P14679
#203100 Albinism, oculocutaneous, type ia; oca1a P14679
#606952 Albinism, oculocutaneous, type ib; oca1b P14679
#103780 Alcohol dependence P08172
P14416
P31645
P47869
#612069 Amyotrophic lateral sclerosis 10, with or without frontotemporal dementia; als10 Q13148
#614373 Amyotrophic lateral sclerosis 16, juvenile; als16 Q99720
#300068 Androgen insensitivity syndrome; ais P10275
#312300 Androgen insensitivity, partial; pais P10275
#218030 Apparent mineralocorticoid excess; ame P80365
#613546 Aromatase deficiency P11511
#139300 Aromatase excess syndrome; aexs P11511
#608584 Asthma-related traits, susceptibility to, 2 Q6W5P4
#612240 Atrial fibrillation, familial, 7; atfb7 P22460
#614740 Basal cell carcinoma, susceptibility to, 7; bcc7 P04637
#613985 Beta-thalassemia P68871
#603902 Beta-thalassemia, dominant inclusion body type P68871
#601816 Bilirubin, serum level of, quantitative trait locus 1; biliqtl1 P22309
#614490 Blood group, junior system; jr Q9UNQ0
#210900 Bloom syndrome; blm P54132
#602025 Body mass index quantitative trait locus 9; bmiq9 P41968
%606641 Body mass index; bmi P37231
#114480 Breast cancer P31749
P38398
#604370 Breast-ovarian cancer, familial, susceptibility to, 1; brovca1 P38398
#300615 Brunner syndrome P21397
#615279 Cardiofaciocutaneous syndrome 3; cfc3 Q02750
#115200 Cardiomyopathy, dilated, 1a; cmd1a P02545
#212112 Cardiomyopathy, dilated, with hypergonadotropic hypogonadism P02545
#609338 Carotid intimal medial thickness 1 P37231
#118300 Charcot-marie-tooth disease and deafness Q01453
#605588 Charcot-marie-tooth disease, axonal, type 2b1; cmt2b1 P02545
#118220 Charcot-marie-tooth disease, demyelinating, type 1a; cmt1a Q01453
#613641 Charcot-marie-tooth disease, recessive intermediate b; cmtrib Q15046
#114500 Colorectal cancer; crc P18054
P31749
P84022
Q14191
#614466 Coronary heart disease, susceptibility to, 6; chds6 P08254
#604931 Cortisone reductase deficiency 1; cortrd1 P28845
#615109 Cowden syndrome 6; cws6 P31749
#218800 Crigler-najjar syndrome, type i P22309
P22310
#606785 Crigler-najjar syndrome, type ii P22309
P22310
#162800 Cyclic neutropenia P08246
#613916 Deafness, autosomal recessive 89; dfnb89 Q15046
#612522 Diabetes mellitus, insulin-dependent, 22; iddm22 P51681
#119900 Digital clubbing, isolated congenital P15428
#607208 Dravet syndrome P18507
#609535 Drug metabolism, poor, cyp2c19-related P33261
#608902 Drug metabolism, poor, cyp2d6-related P10635
#237500 Dubin-johnson syndrome; djs Q92887
#614546 Efavirenz, poor metabolism of P20813
#181350 Emery-dreifuss muscular dystrophy 2, autosomal dominant; edmd2 P02545
#607681 Epilepsy, childhood absence, susceptibility to, 2; eca2 P18507
#612269 Epilepsy, childhood absence, susceptibility to, 5; eca5 P28472
#613060 Epilepsy, idiopathic generalized, susceptibility to, 10; eig10 O14764
#611136 Epilepsy, juvenile myoclonic, susceptibility to, 5; ejm5 P14867
#160120 Episodic ataxia, type 1; ea1 Q09470
#133239 Esophageal cancer P04637
P18054
#615363 Estrogen resistance; estrr P03372
#301500 Fabry disease P06280
#600274 Frontotemporal dementia; ftd P10636
#230200 Galactokinase deficiency P51570
#613659 Gastric cancer P04626
#137215 Gastric cancer, hereditary diffuse; hdgc P04626
#608013 Gaucher disease, perinatal lethal P04062
#230800 Gaucher disease, type i P04062
#230900 Gaucher disease, type ii P04062
#231000 Gaucher disease, type iii P04062
#231005 Gaucher disease, type iiic P04062
#609446 Generalized epilepsy and paroxysmal dyskinesia; gepd Q12791
#604233 Generalized epilepsy with febrile seizures plus, type 1; gefsp1 P18507
#611277 Generalized epilepsy with febrile seizures plus, type 3; gefsp3 P18507
#231095 Ghosal hematodiaphyseal dysplasia; ghdd P24557
#143500 Gilbert syndrome P22309
P22310
#137750 Glaucoma 1, open angle, a; glc1a Q16678
#231300 Glaucoma 3, primary congenital, a; glc3a Q16678
#137760 Glaucoma, primary open angle; poag Q16678
#137800 Glioma susceptibility 1; glm1 O75874
P04626
P37231
#232300 Glycogen storage disease ii P10253
#612933 Glycogen storage disease xi; gsd11 P00338
#139393 Guillain-barre syndrome, familial; gbs Q01453
#605130 Hairy elbows, short stature, facial dysmorphism, and developmental delay Q03164
#610140 Heart-hand syndrome, slovenian type P02545
#140700 Heinz body anemias P68871
#609423 Human immunodeficiency virus type 1, susceptibility to P41597
P51681
#176670 Hutchinson-gilford progeria syndrome; hgps P02545
#237450 Hyperbilirubinemia, rotor type; hblrr Q9NPD5
Q9Y6L6
#237900 Hyperbilirubinemia, transient familial neonatal; hblrtfn P22309
#143860 Hyperchlorhidrosis, isolated O43570
#145000 Hyperparathyroidism 1; hrpt1 O00255
#603373 Hyperthyroidism, familial gestational P16473
#609152 Hyperthyroidism, nonautoimmune P16473
#145900 Hypertrophic neuropathy of dejerine-sottas Q01453
#259100 Hypertrophic osteoarthropathy, primary, autosomal recessive, 1; phoar1 P15428
#275200 Hypothyroidism, congenital, nongoitrous, 1; chng1 P16473
#612244 Inflammatory bowel disease 13; ibd13 P08183
#603932 Intervertebral disc disease; idd P14780
#601626 Leukemia, acute myeloid; aml P36888
#151623 Li-fraumeni syndrome 1; lfs1 P04637
#151660 Lipodystrophy, familial partial, type 2; fpld2 P02545
#604367 Lipodystrophy, familial partial, type 3; fpld3 P37231
#613795 Loeys-dietz syndrome, type 3; lds3 P84022
#613688 Long qt syndrome 2; lqt2 Q12809
#211980 Lung cancer P00533
P04626
P04637
#608516 Major depressive disorder; mdd P08172
#248370 Mandibuloacral dysplasia with type a lipodystrophy; mada P02545
#174800 Mccune-albright syndrome; mas P63092
#614104 Mental retardation, autosomal dominant 7; mrd7 Q13627
#300705 Mental retardation, x-linked 17; mrx17 Q99714
%300852 Mental retardation, x-linked 88; mrx88 P50052
#300220 Mental retardation, x-linked, syndromic 10; mrxs10 Q99714
#613073 Metaphyseal anadysplasia 2; mandp2 P14780
#259600 Multicentric osteolysis, nodulosis, and arthropathy; mona P08253
#131100 Multiple endocrine neoplasia, type i; men1 O00255
#126200 Multiple sclerosis, susceptibility to; ms P08575
#613205 Muscular dystrophy, congenital, lmna-related P02545
#159001 Muscular dystrophy, limb-girdle, type 1b; lgmd1b P02545
#607948 Mycobacterium tuberculosis, susceptibility to P11473
#159900 Myoclonic dystonia P14416
#160900 Myotonic dystrophy 1; dm1 Q9NR56
#162500 Neuropathy, hereditary, with liability to pressure palsies; hnpp Q01453
#202700 Neutropenia, severe congenital, 1, autosomal dominant; scn1 P08246
#257220 Niemann-pick disease, type c1; npc1 O15118
#601665 Obesity P32245
P37231
#164230 Obsessive-compulsive disorder; ocd P31645
#604715 Orthostatic intolerance P23975
#166350 Osseous heteroplasia, progressive; poh P63092
#259730 Osteopetrosis, autosomal recessive 3; optb3 P00918
#167000 Ovarian cancer P04626
P38398
#614320 Pancreatic cancer, susceptibility to, 4; pnca4 P38398
#260500 Papilloma of choroid plexus; cpp P04637
#168600 Parkinson disease, late-onset; pd P04062
#260540 Parkinson-dementia syndrome P10636
#613135 Parkinsonism-dystonia, infantile; pkdys Q01959
#604229 Peters anomaly Q16678
#172700 Pick disease of brain P10636
#102200 Pituitary adenoma, growth hormone-secreting P63092
#601399 Platelet disorder, familial, with associated myeloid malignancy Q01196
#176920 Proteus syndrome P31749
#103580 Pseudohypoparathyroidism, type ia; php1a P63092
#603233 Pseudohypoparathyroidism, type ib; php1b P63092
#612462 Pseudohypoparathyroidism, type ic; php1c P63092
#607276 Resting heart rate, variation in P08588
#275210 Restrictive dermopathy, lethal P02545
#600852 Retinitis pigmentosa 17; rp17 P22748
#604906 Schizophrenia 9; sczd9 P49798
#181500 Schizophrenia; sczd P49798
#608971 Severe combined immunodeficiency, autosomal recessive, t cell-negative, b cell-positive, nk cell-positive P08575
#609620 Short qt syndrome 1; sqt1 Q12809
#603903 Sickle cell anemia P68871
#601800 Skin/hair/eye pigmentation, variation in, 3; shep3 P14679
#313200 Spinal and bulbar muscular atrophy, x-linked 1; smax1 P10275
#253300 Spinal muscular atrophy, type i; sma1 Q16637
#253550 Spinal muscular atrophy, type ii; sma2 Q16637
#253400 Spinal muscular atrophy, type iii; sma3 Q16637
#271150 Spinal muscular atrophy, type iv; sma4 Q16637
#183090 Spinocerebellar ataxia 2; sca2 Q99700
#607250 Spinocerebellar ataxia, autosomal recessive, with axonal neuropathy; scan1 Q9NUW8
#602111 Spondyloepimetaphyseal dysplasia, missouri type P45452
#275355 Squamous cell carcinoma, head and neck; hnscc O14763
P04637
%612223 Stature quantitative trait locus 11; stqtl11 Q00534
#601104 Supranuclear palsy, progressive, 1; psnp1 P10636
#187950 Thrombocythemia 1; thcyt1 P40225
#188570 Thyroid hormone resistance, generalized, autosomal dominant; grth P10828
#274300 Thyroid hormone resistance, generalized, autosomal recessive; grth P10828
#145650 Thyroid hormone resistance, selective pituitary; prth P10828
#190300 Tremor, hereditary essential, 1; etm1 P35462
#138900 Uric acid concentration, serum, quantitative trait locus 1; uaqtl1 Q9UNQ0
#277440 Vitamin d-dependent rickets, type 2a; vddr2a P11473
#277700 Werner syndrome; wrn Q14191
#610379 West nile virus, susceptibility to P51681
#278300 Xanthinuria, type i P47989
#278750 Xeroderma pigmentosum, variant type; xpv Q9Y253
#112100 Yt blood group antigen P22303

KEGG DISEASE (136)

KEGG name UniProt
H00033 Adrenal carcinoma O00255 (related)
P04637 (related)
H00034 Carcinoid O00255 (related)
H00045 Malignant islet cell carcinoma O00255 (related)
H00246 Primary hyperparathyroidism O00255 (related)
H01102 Pituitary adenomas O00255 (related)
H00783 Febrile seizures O14764 (related)
P18507 (related)
H00136 Niemann-Pick disease type C (NPC) O15118 (related)
H01302 Hyperchlorhidrosis isolated (HCHLH) O43570 (related)
H00021 Renal cell carcinoma O43570 (marker)
P04637 (marker)
Q16790 (marker)
H00069 Glycogen storage diseases (GSD) P00338 (related)
P10253 (related)
H00010 Multiple myeloma P00338 (marker)
P04637 (related)
H00023 Testicular cancer P00338 (marker)
H00035 Ewing's sarcoma P00338 (marker)
H00043 Neuroblastoma P00338 (marker)
H00016 Oral cancer P00533 (related)
P00533 (marker)
P04637 (related)
P04637 (marker)
H00017 Esophageal cancer P00533 (related)
P04637 (related)
P04637 (marker)
P35354 (related)
H00018 Gastric cancer P00533 (related)
P04626 (related)
P04637 (related)
H00022 Bladder cancer P00533 (related)
P04626 (related)
P04637 (related)
P68871 (marker)
H00028 Choriocarcinoma P00533 (related)
P03956 (related)
P04626 (related)
P04637 (related)
P08253 (related)
H00030 Cervical cancer P00533 (related)
P04626 (related)
H00042 Glioma P00533 (related)
P00533 (marker)
P04637 (related)
P04637 (marker)
H00055 Laryngeal cancer P00533 (related)
P00533 (marker)
P04637 (related)
P04637 (marker)
H00241 Combined proximal and distal renal tubular acidosis (RTA type 3) P00918 (related)
H00436 Osteopetrosis P00918 (related)
H00081 Hashimoto's thyroiditis P01215 (marker)
H00082 Graves' disease P01215 (marker)
H00250 Congenital nongoitrous hypothyroidism (CHNG) P01215 (marker)
P16473 (related)
H00264 Charcot-Marie-Tooth disease (CMT) P02545 (related)
Q01453 (related)
Q15046 (related)
H00294 Dilated cardiomyopathy (DCM) P02545 (related)
H00420 Familial partial lipodystrophy (FPL) P02545 (related)
P37231 (related)
H00563 Emery-Dreifuss muscular dystrophy P02545 (related)
H00590 Congenital muscular dystrophies (CMD/MDC) P02545 (related)
H00593 Limb-girdle muscular dystrophy (LGMD) P02545 (related)
H00601 Hutchinson-Gilford progeria syndrome P02545 (related)
H00663 Restrictive dermopathy P02545 (related)
H00665 Mandibuloacral dysplasia P02545 (related)
H01216 Left ventricular noncompaction (LVNC) P02545 (related)
H00026 Endometrial Cancer P03372 (marker)
P04626 (related)
P04637 (related)
Q92731 (marker)
H00066 Lewy body dementia (LBD) P04062 (related)
H00126 Gaucher disease P04062 (related)
H00426 Defects in the degradation of ganglioside P04062 (related)
H00810 Progressive myoclonic epilepsy (PME) P04062 (related)
H00599 46,XX disorders of sex development (Disorders related to androgen excess) P04150 (related)
P11511 (related)
H00019 Pancreatic cancer P04626 (related)
P04637 (related)
P04637 (marker)
H00027 Ovarian cancer P04626 (related)
P04637 (related)
P38398 (related)
H00031 Breast cancer P04626 (related)
P04626 (marker)
P04637 (related)
P38398 (related)
H00046 Cholangiocarcinoma P04626 (related)
P04637 (related)
P35354 (related)
H00004 Chronic myeloid leukemia (CML) P04637 (related)
Q01196 (related)
H00005 Chronic lymphocytic leukemia (CLL) P04637 (related)
P28907 (marker)
H00006 Hairy-cell leukemia P04637 (related)
H00008 Burkitt lymphoma P04637 (related)
H00009 Adult T-cell leukemia P04637 (related)
H00013 Small cell lung cancer P04637 (related)
H00014 Non-small cell lung cancer P04637 (related)
H00015 Malignant pleural mesothelioma P04637 (related)
H00020 Colorectal cancer P04637 (related)
P04637 (marker)
P68871 (marker)
H00025 Penile cancer P04637 (related)
P04637 (marker)
P08253 (related)
P14780 (related)
P35354 (related)
H00029 Vulvar cancer P04637 (related)
H00032 Thyroid cancer P04637 (related)
P37231 (related)
H00036 Osteosarcoma P04637 (related)
P08684 (marker)
H00038 Malignant melanoma P04637 (related)
P14679 (marker)
H00039 Basal cell carcinoma P04637 (related)
H00040 Squamous cell carcinoma P04637 (related)
H00041 Kaposi's sarcoma P04637 (related)
H00044 Cancer of the anal canal P04637 (related)
H00047 Gallbladder cancer P04637 (related)
H00048 Hepatocellular carcinoma P04637 (related)
H00881 Li-Fraumeni syndrome P04637 (related)
H01007 Choroid plexus papilloma P04637 (related)
H00093 Combined immunodeficiencies (CIDs) P06239 (related)
H00125 Fabry disease P06280 (related)
H00079 Asthma P07550 (related)
H00100 Neutropenic disorders P08246 (related)
H00472 Torg-Winchester syndrome P08253 (related)
H00091 T-B+Severe combined immunodeficiencies (SCIDs) P08575 (related)
H00024 Prostate cancer P10275 (related)
H00062 Spinal and bulbar muscular atrophy (SBMA) P10275 (related)
H00608 46,XY disorders of sex development (Disorders in androgen synthesis or action) P10275 (related)
H00609 46,XY disorders of sex development (Other) P10275 (related)
H00058 Amyotrophic lateral sclerosis (ALS) P10636 (related)
Q13148 (related)
H00077 Progressive supranuclear palsy (PSP) P10636 (related)
H00078 Frontotemporal lobar degeneration (FTLD) P10636 (related)
H00249 Thyroid hormone resistance syndrome P10828 (related)
H00342 Tuberculosis P11473 (related)
H00784 Localized autosomal recessive hypotrichosis P11473 (related)
H01143 Vitamin D-dependent rickets P11473 (related)
H00794 Aromatase excess syndrome P11511 (related)
H01205 Coumarin resistance P11712 (related)
H00168 Oculocutaneous albinism (OCA) P14679 (related)
H00479 Metaphyseal dysplasias P14780 (related)
P45452 (related)
H00808 Idiopathic generalized epilepsies (IGEs) P14867 (related)
P18507 (related)
H00457 Primary hypertrophic osteoarthropathy (PHO) P15428 (related)
H01246 Isolated congenital nail clubbing (ICNC) P15428 (related)
H01269 Congenital hyperthyroidism P16473 (related)
H00548 Brunner syndrome P21397 (related)
H00208 Hyperbilirubinemia P22309 (related)
Q92887 (related)
H00731 Atrial fibrillation P22460 (related)
H00527 Retinitis pigmentosa (RP) P22748 (related)
H01031 Orthostatic intolerance (OI) P23975 (related)
H00490 Diaphyseal dysplasia with anemia (Ghosal) P24557 (related)
H01111 Cortisone reductase deficiency (CRD) P28845 (related)
H00539 PTEN hamartoma tumor syndrome (PHTS) P31749 (related)
H01171 Poor drug metabolism (PM) P33261 (related)
H00003 Acute myeloid leukemia (AML) P36888 (related)
Q01196 (related)
Q01196 (marker)
Q13951 (marker)
H00409 Type II diabetes mellitus P37231 (related)
H00227 Congenital amegakaryocytic thrombocytopenia (CAMT) P40225 (marker)
H00192 Xanthinuria P47989 (related)
H00480 Non-syndromic X-linked mental retardation P50052 (related)
Q99714 (related)
H00070 Galactosemia P51570 (related)
H00606 Early infantile epileptic encephalopathy P53779 (related)
H00094 DNA repair defects P54132 (related)
H00296 Defects in RecQ helicases P54132 (related)
Q14191 (related)
H00244 Pseudohypoparathyroidism P63092 (related)
H00441 Progressive osseous heteroplasia (POH) P63092 (related)
H00501 Fibrous dysplasia, polyostotic P63092 (related)
H00228 Thalassemia P68871 (related)
H00229 Sickle cell anemia (SCA) P68871 (related)
H00259 Apparent mineralocorticoid excess syndrome P80365 (related)
H00001 Acute lymphoblastic leukemia (ALL) (precursor B lymphoblastic leukemia) Q01196 (related)
Q01196 (marker)
Q03164 (related)
Q03164 (marker)
H00978 Thrombocytopenia (THC) Q01196 (related)
H01296 Hereditary neuropathy with liability to pressure palsies (HNPP) Q01453 (related)
H00523 Noonan syndrome and related disorders Q02750 (related)
H00002 Acute lymphoblastic leukemia (ALL) (precursor T lymphoblastic leukemia) Q03164 (related)
H00749 Episodic ataxias Q09470 (related)
H01258 Generalized epilepsy and paroxysmal dyskinesia (GEPD) Q12791 (related)
H00720 Long QT syndrome Q12809 (related)
H00725 Short QT syndrome Q12809 (related)
H00455 Spinal muscular atrophy (SMA) Q16637 (related)
H00612 Primary open angle glaucoma Q16678 (related)
H01075 Peters anomaly Q16678 (related)
H01159 Anterior segment dysgenesis (ASD) Q16678 (related)
H01203 Primary congenital glaucoma (PCG) Q16678 (related)
H00063 Spinocerebellar ataxia (SCA) Q99700 (related)
Q9NUW8 (related)
H00658 Syndromic X-linked mental retardation Q99714 (related)
H00925 2-Methyl-3-hydroxybutyryl-CoA dehydrogenase (MHBD) deficiency Q99714 (related)
H00403 Disorders of nucleotide excision repair Q9Y253 (related)

Diseases related to CTD interactions

37 disease in interactions with metabolites

MESH or OMIM name KNApSAcK
metabolite
D011565 Psoriasis C00000575
C00000576
C00002502
D010146 Pain C00005374
C00002654
D009182 Mycosis Fungoides C00000576
C00002502
D014820 Vitiligo C00000576
C00002502
D004485 Eczema C00000576
C00002502
D056486 Drug-Induced Liver Injury C00000576
C00003817
D011693 Purpura C00000576
D020258 Neurotoxicity Syndromes C00001193
D001930 Brain Injuries C00001193
D006261 Headache C00000576
D007674 Kidney Diseases C00000576
D017114 Liver Failure, Acute C00000576
D008175 Lung Neoplasms C00000576
D016410 Lymphoma, T-Cell, Cutaneous C00000576
D008881 Migraine Disorders C00000576
D010787 Photosensitivity Disorders C00000575
D009325 Nausea C00000576
D000857 Olfaction Disorders C00000576
D015746 Abdominal Pain C00000576
D007319 Sleep Initiation and Maintenance Disorders C00000576
D014006 Tinea Capitis C00000576
D015837 Vestibular Diseases C00000576
D006505 Hepatitis C00000575
D011605 Psychoses, Substance-Induced C00002502
D000257 Adenoviridae Infections C00003817
D001943 Breast Neoplasms C00003817
D003110 Colonic Neoplasms C00003817
D009361 Neoplasm Invasiveness C00003817
D009362 Neoplasm Metastasis C00003817
D011041 Poisoning C00003817
D011471 Prostatic Neoplasms C00003817
D009202 Cardiomyopathies C00000674
D002386 Cataract C00000674
D005483 Flushing C00000674
D006529 Hepatomegaly C00000674
D008103 Liver Cirrhosis C00000674
D010051 Ovarian Neoplasms C00000674