Pinus pinaster
Species
KNApSAcK Entry
| Organism name | Pinus pinaster |
|---|---|
| Genus | Pinus |
| Family | Pinaceae |
| Kingdom | Plantae |
NCBI taxonomy
Entry
| Linked NCBI taxonomy name | Pinus pinaster |
|---|---|
| Linked NCBI taxonomy ID | 71647 |
| Linked level | species |
Family
| Family in NCBI taxonomy | Pinaceae |
|---|---|
| ID | 3318 |
Kingdom (Superkingdom)
| Kingdom (Superkingdom) in NCBI taxonomy | Viridiplantae |
|---|---|
| ID | 33090 |
Plant class
| Plant class | Spermatophyta |
|---|---|
| ID | 58024 |
Natural Activity
List (37)
| Species | Activity |
|---|---|
| Pinus pinaster Aiton | Analgesic |
| Pinus pinaster Aiton | Anti-HIV |
| Pinus pinaster Aiton | Antiaggregant |
| Pinus pinaster Aiton | Antiaging |
| Pinus pinaster Aiton | Antiallergic |
| Pinus pinaster Aiton | Antiamyloid |
| Pinus pinaster Aiton | Antianaphylactic |
| Pinus pinaster Aiton | Antianemic |
| Pinus pinaster Aiton | Antiasthmatic |
| Pinus pinaster Aiton | Antiatherogenic |
| Pinus pinaster Aiton | Antibacterial |
| Pinus pinaster Aiton | Anticancer |
| Pinus pinaster Aiton | Antidematotic |
| Pinus pinaster Aiton | Antiedemic |
| Pinus pinaster Aiton | Antiexudative |
| Pinus pinaster Aiton | Antihistaminic |
| Pinus pinaster Aiton | Antiinflammatory |
| Pinus pinaster Aiton | Antioxidant |
| Pinus pinaster Aiton | Antiplaque |
| Pinus pinaster Aiton | Antiradicular |
| Pinus pinaster Aiton | Antiseptic |
| Pinus pinaster Aiton | Antisickling |
| Pinus pinaster Aiton | Antithromboxane |
| Pinus pinaster Aiton | Antiviral |
| Pinus pinaster Aiton | Apoptotic |
| Pinus pinaster Aiton | Cancer Preventive |
| Pinus pinaster Aiton | Capillaritonic |
| Pinus pinaster Aiton | Hemopoietic |
| Pinus pinaster Aiton | Hyaluronidase Inhibitor |
| Pinus pinaster Aiton | Immunomodulator |
| Pinus pinaster Aiton | Lipolytic |
| Pinus pinaster Aiton | Lipoxygenase Inhibitor |
| Pinus pinaster Aiton | NO-Genic |
| Pinus pinaster Aiton | Peroxidase Inhibitor |
| Pinus pinaster Aiton | Retinoprotective |
| Pinus pinaster Aiton | Sunscreen |
| Pinus pinaster Aiton | Xanthine-Oxidase Inhibitor |
Metabolite list (3)
| KNApSAcK ID | name | ChEMBL link | CTD link |
# of proteins in
ChEMBL interaction / related OMIM / related KEGG DISEASE |
# of genes in
CTD interaction / related diseases |
KCF-S
cluster |
phytochemical
cluster |
figure |
|---|---|---|---|---|---|---|---|---|
C00002897
|
Pinosylvin
/ Pinosylvine / 3,5-Dihydroxystilbene |
CHEMBL101506
CHEMBL2203685 |
1 / 0 / 1 | No. 295 | No. 13 |
|
||
|
C00002898
|
Pinosylvin methyl ether
/ 3-Hydroxy-5-methoxystilbene |
CHEMBL186366
|
18 / 39 / 57 | No. 295 | No. 13 |
|
||
|
C00022109
|
Geranyllinalool
|
No. 706 |
|
Human Protein / Gene in interactions
19 ChEMBL Protein in interactions
| accession | description | class description | KNApSAcK metabolite in interactions |
# of diseases
(OMIM / KEGG) |
|---|---|---|---|---|
| P04637 | Cellular tumor antigen p53 | Transcription Factor | C00002898 | 7 / 37 |
| Q16637 | Survival motor neuron protein | Unclassified protein | C00002898 | 4 / 1 |
| O75604 | Ubiquitin carboxyl-terminal hydrolase 2 | Enzyme | C00002898 | 0 / 0 |
| P37840 | Alpha-synuclein | Unclassified protein | C00002898 | 4 / 2 |
| P00352 | Retinal dehydrogenase 1 | Enzyme | C00002898 | 0 / 0 |
| O75496 | Geminin | Unclassified protein | C00002898 | 0 / 0 |
| P38398 | Breast cancer type 1 susceptibility protein | Enzyme | C00002898 | 4 / 2 |
| P43220 | Glucagon-like peptide 1 receptor | Glucagon-like peptide receptor | C00002898 | 0 / 0 |
| P63092 | Guanine nucleotide-binding protein G(s) subunit alpha isoforms short | Other membrane protein | C00002898 | 7 / 3 |
| O94782 | Ubiquitin carboxyl-terminal hydrolase 1 | Enzyme | C00002898 | 0 / 0 |
| Q99714 | 3-hydroxyacyl-CoA dehydrogenase type-2 | Enzyme | C00002898 | 3 / 3 |
| P15428 | 15-hydroxyprostaglandin dehydrogenase [NAD(+)] | Enzyme | C00002898 | 2 / 2 |
| P08684 | Cytochrome P450 3A4 | Cytochrome P450 3A4 | C00002898 | 0 / 1 |
| P10636 | Microtubule-associated protein tau | Unclassified protein | C00002898 | 4 / 3 |
| P06239 | Tyrosine-protein kinase Lck | Src | C00002897 | 0 / 1 |
| B2RXH2 | Lysine-specific demethylase 4E | Enzyme | C00002898 | 0 / 0 |
| O75874 | Isocitrate dehydrogenase [NADP] cytoplasmic | Enzyme | C00002898 | 1 / 0 |
| O00255 | Menin | Unclassified protein | C00002898 | 2 / 5 |
| Q03164 | Histone-lysine N-methyltransferase 2A | Enzyme | C00002898 | 1 / 2 |
Related Diseases
Diseases related to proteins in ChEMBL interactions
OMIM (39)
| OMIM | preferred title | UniProt |
|---|---|---|
| #300438 | 17-beta-hydroxysteroid dehydrogenase x deficiency |
Q99714
|
| #219080 | Acth-independent macronodular adrenal hyperplasia; aimah |
P63092
|
| #202300 | Adrenocortical carcinoma, hereditary; adcc |
P04637
|
| #614740 | Basal cell carcinoma, susceptibility to, 7; bcc7 |
P04637
|
| #114480 | Breast cancer |
P38398
|
| #604370 | Breast-ovarian cancer, familial, susceptibility to, 1; brovca1 |
P38398
|
| #127750 | Dementia, lewy body; dlb |
P37840
|
| #119900 | Digital clubbing, isolated congenital |
P15428
|
| #133239 | Esophageal cancer |
P04637
|
| #600274 | Frontotemporal dementia; ftd |
P10636
|
| #137800 | Glioma susceptibility 1; glm1 |
O75874
|
| #605130 | Hairy elbows, short stature, facial dysmorphism, and developmental delay |
Q03164
|
| #145000 | Hyperparathyroidism 1; hrpt1 |
O00255
|
| #259100 | Hypertrophic osteoarthropathy, primary, autosomal recessive, 1; phoar1 |
P15428
|
| #151623 | Li-fraumeni syndrome 1; lfs1 |
P04637
|
| #211980 | Lung cancer |
P04637
|
| #174800 | Mccune-albright syndrome; mas |
P63092
|
| #300705 | Mental retardation, x-linked 17; mrx17 |
Q99714
|
| #300220 | Mental retardation, x-linked, syndromic 10; mrxs10 |
Q99714
|
| #131100 | Multiple endocrine neoplasia, type i; men1 |
O00255
|
| #166350 | Osseous heteroplasia, progressive; poh |
P63092
|
| #167000 | Ovarian cancer |
P38398
|
| #614320 | Pancreatic cancer, susceptibility to, 4; pnca4 |
P38398
|
| #260500 | Papilloma of choroid plexus; cpp |
P04637
|
| #168601 | Parkinson disease 1, autosomal dominant; park1 |
P37840
|
| #605543 | Parkinson disease 4, autosomal dominant; park4 |
P37840
|
| #168600 | Parkinson disease, late-onset; pd |
P37840
|
| #260540 | Parkinson-dementia syndrome |
P10636
|
| #172700 | Pick disease of brain |
P10636
|
| #102200 | Pituitary adenoma, growth hormone-secreting |
P63092
|
| #103580 | Pseudohypoparathyroidism, type ia; php1a |
P63092
|
| #603233 | Pseudohypoparathyroidism, type ib; php1b |
P63092
|
| #612462 | Pseudohypoparathyroidism, type ic; php1c |
P63092
|
| #253300 | Spinal muscular atrophy, type i; sma1 |
Q16637
|
| #253550 | Spinal muscular atrophy, type ii; sma2 |
Q16637
|
| #253400 | Spinal muscular atrophy, type iii; sma3 |
Q16637
|
| #271150 | Spinal muscular atrophy, type iv; sma4 |
Q16637
|
| #275355 | Squamous cell carcinoma, head and neck; hnscc |
P04637
|
| #601104 | Supranuclear palsy, progressive, 1; psnp1 |
P10636
|
KEGG DISEASE (58)
| KEGG | name | UniProt |
|---|---|---|
| H00033 | Adrenal carcinoma |
O00255
(related)
P04637 (related) |
| H00034 | Carcinoid |
O00255
(related)
|
| H00045 | Malignant islet cell carcinoma |
O00255
(related)
|
| H00246 | Primary hyperparathyroidism |
O00255
(related)
|
| H01102 | Pituitary adenomas |
O00255
(related)
|
| H00004 | Chronic myeloid leukemia (CML) |
P04637
(related)
|
| H00005 | Chronic lymphocytic leukemia (CLL) |
P04637
(related)
|
| H00006 | Hairy-cell leukemia |
P04637
(related)
|
| H00008 | Burkitt lymphoma |
P04637
(related)
|
| H00009 | Adult T-cell leukemia |
P04637
(related)
|
| H00010 | Multiple myeloma |
P04637
(related)
|
| H00013 | Small cell lung cancer |
P04637
(related)
|
| H00014 | Non-small cell lung cancer |
P04637
(related)
|
| H00015 | Malignant pleural mesothelioma |
P04637
(related)
|
| H00016 | Oral cancer |
P04637
(related)
P04637 (marker) |
| H00017 | Esophageal cancer |
P04637
(related)
P04637 (marker) |
| H00018 | Gastric cancer |
P04637
(related)
|
| H00019 | Pancreatic cancer |
P04637
(related)
P04637 (marker) |
| H00020 | Colorectal cancer |
P04637
(related)
P04637 (marker) |
| H00022 | Bladder cancer |
P04637
(related)
|
| H00025 | Penile cancer |
P04637
(related)
P04637 (marker) |
| H00026 | Endometrial Cancer |
P04637
(related)
|
| H00027 | Ovarian cancer |
P04637
(related)
P38398 (related) |
| H00028 | Choriocarcinoma |
P04637
(related)
|
| H00029 | Vulvar cancer |
P04637
(related)
|
| H00031 | Breast cancer |
P04637
(related)
P38398 (related) |
| H00032 | Thyroid cancer |
P04637
(related)
|
| H00036 | Osteosarcoma |
P04637
(related)
P08684 (marker) |
| H00038 | Malignant melanoma |
P04637
(related)
|
| H00039 | Basal cell carcinoma |
P04637
(related)
|
| H00040 | Squamous cell carcinoma |
P04637
(related)
|
| H00041 | Kaposi's sarcoma |
P04637
(related)
|
| H00042 | Glioma |
P04637
(related)
P04637 (marker) |
| H00044 | Cancer of the anal canal |
P04637
(related)
|
| H00046 | Cholangiocarcinoma |
P04637
(related)
|
| H00047 | Gallbladder cancer |
P04637
(related)
|
| H00048 | Hepatocellular carcinoma |
P04637
(related)
|
| H00055 | Laryngeal cancer |
P04637
(related)
P04637 (marker) |
| H00881 | Li-Fraumeni syndrome |
P04637
(related)
|
| H01007 | Choroid plexus papilloma |
P04637
(related)
|
| H00021 | Renal cell carcinoma |
P04637
(marker)
|
| H00093 | Combined immunodeficiencies (CIDs) |
P06239
(related)
|
| H00058 | Amyotrophic lateral sclerosis (ALS) |
P10636
(related)
|
| H00077 | Progressive supranuclear palsy (PSP) |
P10636
(related)
|
| H00078 | Frontotemporal lobar degeneration (FTLD) |
P10636
(related)
|
| H00457 | Primary hypertrophic osteoarthropathy (PHO) |
P15428
(related)
|
| H01246 | Isolated congenital nail clubbing (ICNC) |
P15428
(related)
|
| H00057 | Parkinson's disease (PD) |
P37840
(related)
|
| H00066 | Lewy body dementia (LBD) |
P37840
(related)
|
| H00244 | Pseudohypoparathyroidism |
P63092
(related)
|
| H00441 | Progressive osseous heteroplasia (POH) |
P63092
(related)
|
| H00501 | Fibrous dysplasia, polyostotic |
P63092
(related)
|
| H00001 | Acute lymphoblastic leukemia (ALL) (precursor B lymphoblastic leukemia) |
Q03164
(related)
Q03164 (marker) |
| H00002 | Acute lymphoblastic leukemia (ALL) (precursor T lymphoblastic leukemia) |
Q03164
(related)
|
| H00455 | Spinal muscular atrophy (SMA) |
Q16637
(related)
|
| H00480 | Non-syndromic X-linked mental retardation |
Q99714
(related)
|
| H00658 | Syndromic X-linked mental retardation |
Q99714
(related)
|
| H00925 | 2-Methyl-3-hydroxybutyryl-CoA dehydrogenase (MHBD) deficiency |
Q99714
(related)
|