Species

KNApSAcK Entry

Organism name Ferula hermonis
Genus Ferula
Family Apiaceae
Kingdom Plantae

NCBI taxonomy

Entry

Linked NCBI taxonomy name Ferula hermonis
Linked NCBI taxonomy ID 662815
Linked level species

Family

Family in NCBI taxonomy Apiaceae
ID 4037

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy Viridiplantae
ID 33090

Plant class

Plant class asterids
ID 71274

Metabolite list (8)

KNApSAcK ID name ChEMBL link CTD link # of proteins in
ChEMBL interaction
/ related OMIM
/ related KEGG DISEASE
# of genes in
CTD interaction
/ related diseases
KCF-S
cluster
phytochemical
cluster
figure
C00021386 External link 512 Teferidin
CHEMBL516694
CHEMBL1999942
1 / 1 / 1 No. 327
C00021389 External link 512 Ferutinin
/ Jaeschkeanadiol p-hydroxybenzoate
CHEMBL465040
C111068
3 / 1 / 1 No. 327
C00003103 External link 512 (+)-alpha-Bisabolol
CHEMBL519167
CHEMBL491186
CHEMBL477832
CHEMBL1096927
CHEMBL1171719
CHEMBL1561544
CHEMBL2104360
8 / 4 / 13 No. 541 No. 38
C00045919 External link 512 Epoxyjaeschkeanadiol
/ Jaeschkeanadiol alpha-epoxide
CHEMBL513927
No. 1209
C00021385 External link 512 Ferutinol
/ Jaeschkeanadiol
CHEMBL516572
No. 1295
C00042002 External link 512 (1R,4R)-4-Hydroxydauca-7-ene-6-one
/ (+)-(1R,4R)-4-Hydroxydauca-7-ene-6-one
CHEMBL513022
No. 2581
C00045514 External link 512 14-(4'-Hydroxy-3'-methoxybenzoyloxy)dauc-4,8-diene
/ (-)-14-(4'-Hydroxy-3'-methoxybenzoyloxy)dauc-4,8-diene
CHEMBL479150
No. 5524
C00045515 External link 512 14-(4'-Hydroxybenzoyloxy)dauc-4,8-diene
/ (+)-14-(4'-Hydroxybenzoyloxy)dauc-4,8-diene
CHEMBL479149
No. 5524

Human Protein / Gene in interactions

11 ChEMBL Protein in interactions

accession description class description KNApSAcK metabolite in interactions # of diseases
(OMIM / KEGG)
P03372 Estrogen receptor NR3A1 C00021386 C00021389 1 / 1
O76074 cGMP-specific 3',5'-cyclic phosphodiesterase PDE_5A C00021389 0 / 0
P40763 Signal transducer and activator of transcription 3 Transcription Factor C00003103 1 / 2
O94782 Ubiquitin carboxyl-terminal hydrolase 1 Enzyme C00003103 0 / 0
P28482 Mitogen-activated protein kinase 1 Erk C00003103 0 / 0
Q92731 Estrogen receptor beta NR3A2 C00021389 0 / 1
P35354 Prostaglandin G/H synthase 2 Oxidoreductase C00003103 0 / 3
P16050 Arachidonate 15-lipoxygenase Enzyme C00003103 0 / 0
P08684 Cytochrome P450 3A4 Cytochrome P450 3A4 C00003103 0 / 1
O00255 Menin Unclassified protein C00003103 2 / 5
Q03164 Histone-lysine N-methyltransferase 2A Enzyme C00003103 1 / 2

Related Diseases

Diseases related to proteins in ChEMBL interactions

OMIM (5)

OMIM preferred title UniProt
#615363 Estrogen resistance; estrr P03372
#605130 Hairy elbows, short stature, facial dysmorphism, and developmental delay Q03164
#147060 Hyper-ige recurrent infection syndrome, autosomal dominant P40763
#145000 Hyperparathyroidism 1; hrpt1 O00255
#131100 Multiple endocrine neoplasia, type i; men1 O00255

KEGG DISEASE (14)

KEGG name UniProt
H00033 Adrenal carcinoma O00255 (related)
H00034 Carcinoid O00255 (related)
H00045 Malignant islet cell carcinoma O00255 (related)
H00246 Primary hyperparathyroidism O00255 (related)
H01102 Pituitary adenomas O00255 (related)
H00026 Endometrial Cancer P03372 (marker)
Q92731 (marker)
H00036 Osteosarcoma P08684 (marker)
H00017 Esophageal cancer P35354 (related)
H00025 Penile cancer P35354 (related)
H00046 Cholangiocarcinoma P35354 (related)
H00016 Oral cancer P40763 (related)
H00107 Other well-defined immunodeficiency syndromes P40763 (related)
H00001 Acute lymphoblastic leukemia (ALL) (precursor B lymphoblastic leukemia) Q03164 (related)
Q03164 (marker)
H00002 Acute lymphoblastic leukemia (ALL) (precursor T lymphoblastic leukemia) Q03164 (related)