Thapsia garganica

• Index
• Plant Species
• Metabolite list (7)
• Human Protein
  / Gene in interactions
• Related Diseases

Species

KNApSAcK Entry

Organism name	Thapsia garganica
Genus	Thapsia
Family	Apiaceae
Kingdom	Plantae

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NCBI taxonomy

Entry

Linked NCBI taxonomy name	Thapsia garganica
Linked NCBI taxonomy ID	79022
Linked level	species

Family

Family in NCBI taxonomy	Apiaceae
ID	4037

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy	Viridiplantae
ID	33090

Plant class

Plant class	asterids
ID	71274

Metabolite list (7)

KNApSAcK ID	name	ChEMBL link	CTD link	# of proteins in ChEMBL interaction / related OMIM / related KEGG DISEASE	# of genes in CTD interaction / related diseases	KCF-S cluster	phytochemical cluster	figure
C00035137	Neohelmanthicin D / (-)-Neohelmanthicin D					No. 1913
C00035136	Neohelmanthicin C					No. 1913
C00035135	Neohelmanthicin B					No. 1913
C00035134	Neohelmanthicin A / (-)-Neohelmanthicin A					No. 1913
C00020716	Thapsivillosin K					No. 2100	No. 38
C00020715	Thapsigargicin	CHEMBL328508 CHEMBL1537509	C046319	16 / 11 / 9		No. 2100	No. 38
C00003375	Thapsigargin	CHEMBL96926 CHEMBL192566 CHEMBL1355952	D019284	45 / 52 / 75	157 / 0	No. 2100	No. 38

Human Protein / Gene in interactions

50 ChEMBL Protein in interactions

accession	description	class description	KNApSAcK metabolite in interactions	# of diseases (OMIM / KEGG)
P06746	DNA polymerase beta	Enzyme	C00003375 C00020715	0 / 0
P10636	Microtubule-associated protein tau	Unclassified protein	C00003375 C00020715	4 / 3
P27695	DNA-(apurinic or apyrimidinic site) lyase	Enzyme	C00003375 C00020715	0 / 0
Q6W5P4	Neuropeptide S receptor	Neuropeptide receptor	C00003375 C00020715	1 / 0
Q96QE3	ATPase family AAA domain-containing protein 5	Unclassified protein	C00003375 C00020715	0 / 0
O15118	Niemann-Pick C1 protein	Unclassified protein	C00003375 C00020715	1 / 1
P28482	Mitogen-activated protein kinase 1	Erk	C00003375 C00020715	0 / 0
P06280	Alpha-galactosidase A	Enzyme	C00003375 C00020715	1 / 1
Q03164	Histone-lysine N-methyltransferase 2A	Enzyme	C00003375 C00020715	1 / 2
P51151	Ras-related protein Rab-9A	Unclassified protein	C00003375 C00020715	0 / 0
O14983	Sarcoplasmic/endoplasmic reticulum calcium ATPase 1	Calcium	C00003375 C00020715	1 / 1
P83916	Chromobox protein homolog 1	Unclassified protein	C00003375	0 / 0
P02545	Prelamin-A/C	Unclassified protein	C00003375	11 / 10
P16473	Thyrotropin receptor	Glycohormone receptor	C00003375	3 / 2
P10253	Lysosomal alpha-glucosidase	Hydrolase	C00003375	1 / 1
P11712	Cytochrome P450 2C9	Cytochrome P450 2C9	C00003375	0 / 1
P54132	Bloom syndrome protein	Enzyme	C00003375	1 / 2
P00352	Retinal dehydrogenase 1	Enzyme	C00003375	0 / 0
Q16665	Hypoxia-inducible factor 1-alpha	Transcription Factor	C00003375	0 / 0
Q92830	Histone acetyltransferase KAT2A	Enzyme	C00020715	0 / 0
P42858	Huntingtin	Unclassified protein	C00020715	1 / 1
O75496	Geminin	Unclassified protein	C00003375	0 / 0
P10635	Cytochrome P450 2D6	Cytochrome P450 2D6	C00003375	1 / 0
Q9Y253	DNA polymerase eta	Enzyme	C00003375	1 / 1
Q12809	Potassium voltage-gated channel subfamily H member 2	KCNH, Kv10-12.x (Ether-a-go-go)	C00003375	2 / 2
Q13526	Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1	Enzyme	C00003375	0 / 0
P11021	78 kDa glucose-regulated protein	Unclassified protein	C00003375	0 / 0
O94782	Ubiquitin carboxyl-terminal hydrolase 1	Enzyme	C00003375	0 / 0
P21728	D(1A) dopamine receptor	Dopamine receptor	C00003375	0 / 0
Q99700	Ataxin-2	Unclassified protein	C00003375	1 / 1
P05177	Cytochrome P450 1A2	Cytochrome P450 1A2	C00003375	0 / 0
P15428	15-hydroxyprostaglandin dehydrogenase [NAD(+)]	Enzyme	C00003375	2 / 2
Q9UIF8	Bromodomain adjacent to zinc finger domain protein 2B	Unclassified protein	C00020715	0 / 0
Q01453	Peripheral myelin protein 22	Unclassified protein	C00003375	5 / 2
P17861	X-box-binding protein 1	Unclassified protein	C00020715	1 / 0
P19838	Nuclear factor NF-kappa-B p105 subunit	Transcription Factor	C00003375	0 / 0
P16050	Arachidonate 15-lipoxygenase	Enzyme	C00003375	0 / 0
P33261	Cytochrome P450 2C19	Cytochrome P450 2C19	C00003375	1 / 1
P08684	Cytochrome P450 3A4	Cytochrome P450 3A4	C00003375	0 / 1
Q9UNA4	DNA polymerase iota	Enzyme	C00003375	0 / 0
Q16637	Survival motor neuron protein	Unclassified protein	C00003375	4 / 1
P04637	Cellular tumor antigen p53	Transcription Factor	C00003375	7 / 37
P42345	Serine/threonine-protein kinase mTOR	Enzyme	C00003375	0 / 0
Q99549	M-phase phosphoprotein 8	Unclassified protein	C00003375	0 / 0
Q16236	Nuclear factor erythroid 2-related factor 2	Unclassified protein	C00003375	0 / 0
Q9UBT6	DNA polymerase kappa	Enzyme	C00003375	0 / 0
P46063	ATP-dependent DNA helicase Q1	Enzyme	C00020715	0 / 0
P40225	Thrombopoietin	Unclassified protein	C00003375	1 / 1
Q96KQ7	Histone-lysine N-methyltransferase EHMT2	Enzyme	C00003375	0 / 0
O00255	Menin	Unclassified protein	C00003375	2 / 5

157 Gene in CTD interactions

gene	gene name	gene description	KNApSAcK metabolite in interactions
133	ADM, AM	adrenomedullin	C00003375
150	ADRA2A, ADRA2, ADRA2R, ADRAR, ALPHA2AAR, ZNF32	adrenoceptor alpha 2A	C00003375
79026	AHNAK, AHNAKRS	AHNAK nucleoprotein	C00003375
207	AKT1, AKT, CWS6, PKB, PKB-ALPHA, PRKBA, RAC, RAC-ALPHA	v-akt murine thymoma viral oncogene homolog 1 (EC:2.7.11.1)	C00003375
240	ALOX5, 5-LO, 5-LOX, 5LPG, LOG5	arachidonate 5-lipoxygenase (EC:1.13.11.34)	C00003375
467	ATF3	activating transcription factor 3	C00003375
468	ATF4, CREB-2, CREB2, TAXREB67, TXREB	activating transcription factor 4	C00003375
22926	ATF6, ATF6A	activating transcription factor 6	C00003375
488	ATP2A2, ATP2B, DAR, DD, SERCA2	ATPase, Ca++ transporting, cardiac muscle, slow twitch 2 (EC:3.6.3.8)	C00003375
489	ATP2A3, SERCA3	ATPase, Ca++ transporting, ubiquitous (EC:3.6.3.8)	C00003375
245972	ATP6V0D2, ATP6D2, VMA6	ATPase, H+ transporting, lysosomal 38kDa, V0 subunit d2 (EC:3.6.3.14)	C00003375
581	BAX, BCL2L4	BCL2-associated X protein	C00003375
10282	BET1, HBET1	Bet1 golgi vesicular membrane trafficking protein	C00003375
329	BIRC2, API1, HIAP2, Hiap-2, MIHB, RNF48, c-IAP1, cIAP1	baculoviral IAP repeat containing 2	C00003375
330	BIRC3, AIP1, API2, CIAP2, HAIP1, HIAP1, MALT2, MIHC, RNF49, c-IAP2	baculoviral IAP repeat containing 3	C00003375
672	BRCA1, BRCAI, BRCC1, BROVCA1, IRIS, PNCA4, PPP1R53, PSCP, RNF53	breast cancer 1, early onset	C00003375
675	BRCA2, BRCC2, BROVCA2, FACD, FAD, FAD1, FANCB, FANCD, FANCD1, GLM3, PNCA2	breast cancer 2, early onset	C00003375
773	CACNA1A, APCA, BI, CACNL1A4, CAV2.1, EA2, FHM, HPCA, MHP, MHP1, SCA6	calcium channel, voltage-dependent, P/Q type, alpha 1A subunit	C00003375
796	CALCA, CALC1, CGRP, CGRP-I, CGRP1, CT, KC	calcitonin-related polypeptide alpha	C00003375
811	CALR, CRT, RO, SSA, cC1qR	calreticulin	C00003375
813	CALU	calumenin	C00003375
821	CANX, CNX, IP90, P90	calnexin	C00003375
100506742	CASP12, CASP-12, CASP12P1	caspase 12 (gene/pseudogene)	C00003375
835	CASP2, CASP-2, ICH1, NEDD-2, NEDD2, PPP1R57	caspase 2, apoptosis-related cysteine peptidase (EC:3.4.22.55)	C00003375
836	CASP3, CPP32, CPP32B, SCA-1	caspase 3, apoptosis-related cysteine peptidase (EC:3.4.22.56)	C00003375
837	CASP4, ICE(rel)II, ICEREL-II, ICH-2, Mih1/TX, TX	caspase 4, apoptosis-related cysteine peptidase (EC:3.4.22.57)	C00003375
840	CASP7, CASP-7, CMH-1, ICE-LAP3, LICE2, MCH3	caspase 7, apoptosis-related cysteine peptidase (EC:3.4.22.60)	C00003375
842	CASP9, APAF-3, APAF3, ICE-LAP6, MCH6, PPP1R56	caspase 9, apoptosis-related cysteine peptidase (EC:3.4.22.62)	C00003375
117155	CATSPER2	cation channel, sperm associated 2	C00003375
6347	CCL2, GDCF-2, HC11, HSMCR30, MCAF, MCP-1, MCP1, SCYA2, SMC-CF	chemokine (C-C motif) ligand 2	C00003375
595	CCND1, BCL1, D11S287E, PRAD1, U21B31	cyclin D1	C00003375
901	CCNG2	cyclin G2	C00003375
991	CDC20, CDC20A, bA276H19.3, p55CDC	cell division cycle 20	C00003375
1017	CDK2, p33(CDK2)	cyclin-dependent kinase 2 (EC:2.7.11.22)	C00003375
1063	CENPF, CENF, PRO1779, hcp-1	centromere protein F, 350/400kDa	C00003375
1080	CFTR, ABC35, ABCC7, CF, CFTR/MRP, MRP7, TNR-CFTR, dJ760C5.1	cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7) (EC:3.6.3.49)	C00003375
1081	CGA, CG-ALPHA, FSHA, GPHA1, GPHa, HCG, LHA, TSHA	glycoprotein hormones, alpha polypeptide	C00003375
79094	CHAC1	ChaC, cation transport regulator homolog 1 (E. coli)	C00003375
10036	CHAF1A, CAF-1, CAF1, CAF1B, CAF1P150, P150	chromatin assembly factor 1, subunit A (p150)	C00003375
1152	CKB, B-CK, CKBB	creatine kinase, brain (EC:2.7.3.2)	C00003375
6320	CLEC11A, CLECSF3, LSLCL, P47, SCGF	C-type lectin domain family 11, member A	C00003375
1293	COL6A3	collagen, type VI, alpha 3	C00003375
51138	COPS4, CSN4	COP9 signalosome subunit 4	C00003375
8904	CPNE1, COPN1, CPN1	copine I	C00003375
90993	CREB3L1, OASIS	cAMP responsive element binding protein 3-like 1	C00003375
1429	CRYZ	crystallin, zeta (quinone reductase) (EC:1.6.5.5)	C00003375
1489	CTF1, CT-1, CT1	cardiotrophin 1	C00003375
2920	CXCL2, CINC-2a, GRO2, GROb, MGSA-b, MIP-2a, MIP2, MIP2A, SCYB2	chemokine (C-X-C motif) ligand 2	C00003375
4051	CYP4F3, CPF3, CYP4F, LTB4H	cytochrome P450, family 4, subfamily F, polypeptide 3 (EC:1.14.13.30)	C00003375
1611	DAP	death-associated protein	C00003375
1649	DDIT3, CEBPZ, CHOP, CHOP-10, CHOP10, GADD153	DNA-damage-inducible transcript 3	C00003375
56616	DIABLO, DFNA64, SMAC	diablo, IAP-binding mitochondrial protein	C00003375
51726	DNAJB11, ABBP-2, ABBP2, DJ9, Dj-9, EDJ, ERdj3, ERj3, ERj3p, PRO1080, UNQ537, hDj-9	DnaJ (Hsp40) homolog, subfamily B, member 11	C00003375
4189	DNAJB9, ERdj4, MDG-1, MDG1, MST049, MSTP049	DnaJ (Hsp40) homolog, subfamily B, member 9	C00003375
54431	DNAJC10, ERdj5, JPDI, MTHr, PDIA19	DnaJ (Hsp40) homolog, subfamily C, member 10	C00003375
5611	DNAJC3, ERdj6, HP58, P58, P58IPK, PRKRI	DnaJ (Hsp40) homolog, subfamily C, member 3	C00003375
10570	DPYSL4, CRMP3, DRP-4, ULIP4	dihydropyrimidinase-like 4	C00003375
1950	EGF, HOMG4, URG	epidermal growth factor	C00003375
1958	EGR1, AT225, G0S30, KROX-24, NGFI-A, TIS8, ZIF-268, ZNF225	early growth response 1	C00003375
83939	EIF2A, EIF-2A, MST089, MSTP004, MSTP089	eukaryotic translation initiation factor 2A, 65kDa	C00003375
9451	EIF2AK3, PEK, PERK, WRS	eukaryotic translation initiation factor 2-alpha kinase 3 (EC:2.7.11.1)	C00003375
1965	EIF2S1, EIF-2, EIF-2A, EIF-2alpha, EIF2, EIF2A	eukaryotic translation initiation factor 2, subunit 1 alpha, 35kDa	C00003375
8668	EIF3I, EIF3S2, PRO2242, TRIP-1, TRIP1, eIF3-beta, eIF3-p36	eukaryotic translation initiation factor 3, subunit I	C00003375
1984	EIF5A, EIF-5A, EIF5A1, eIF5AI	eukaryotic translation initiation factor 5A	C00003375
63916	ELMO2, CED-12, CED12, ELMO-2	engulfment and cell motility 2	C00003375
2077	ERF, CRS4, PE-2, PE2	Ets2 repressor factor	C00003375
2081	ERN1, IRE1, IRE1P, IRE1a, hIRE1p	endoplasmic reticulum to nucleus signaling 1 (EC:2.7.11.1)	C00003375
2258	FGF13, FGF-13, FGF2, FHF-2, FHF2	fibroblast growth factor 13	C00003375
23768	FLRT2	fibronectin leucine rich transmembrane protein 2	C00003375
2324	FLT4, FLT41, LMPH1A, PCL, VEGFR3	fms-related tyrosine kinase 4 (EC:2.7.10.1)	C00003375
2353	FOS, AP-1, C-FOS, p55	FBJ murine osteosarcoma viral oncogene homolog	C00003375
2354	FOSB, AP-1, G0S3, GOS3, GOSB	FBJ murine osteosarcoma viral oncogene homolog B	C00003375
1647	GADD45A, DDIT1, GADD45	growth arrest and DNA-damage-inducible, alpha	C00003375
2669	GEM, KIR	GTP binding protein overexpressed in skeletal muscle	C00003375
9527	GOSR1, GOLIM2, GOS-28, GOS28, GOS28/P28, GS28, P28	golgi SNAP receptor complex member 1	C00003375
2936	GSR	glutathione reductase (EC:1.8.1.7)	C00003375
3014	H2AFX, H2A.X, H2A/X, H2AX	H2A histone family, member X	C00003375
3068	HDGF, HMG1L2	hepatoma-derived growth factor	C00003375
3099	HK2, HKII, HXK2	hexokinase 2 (EC:2.7.1.1)	C00003375
7184	HSP90B1, ECGP, GP96, GRP94, TRA1	heat shock protein 90kDa beta (Grp94), member 1	C00003375
3309	HSPA5, BIP, GRP78, MIF2	heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)	C00003375
3313	HSPA9, CSA, GRP-75, GRP75, HSPA9B, MOT, MOT2, MTHSP75, PBP74	heat shock 70kDa protein 9 (mortalin)	C00003375
3336	HSPE1, CPN10, EPF, GROES, HSP10	heat shock 10kDa protein 1	C00003375
3350	HTR1A, 5-HT-1A, 5-HT1A, 5HT1a, ADRB2RL1, ADRBRL1, G-21, PFMCD	5-hydroxytryptamine (serotonin) receptor 1A, G protein-coupled	C00003375
50615	IL21R, CD360, NILR	interleukin 21 receptor	C00003375
3569	IL6, BSF2, HGF, HSF, IFNB2, IL-6	interleukin 6 (interferon, beta 2)	C00003375
3576	IL8, CXCL8, GCP-1, GCP1, LECT, LUCT, LYNAP, MDNCF, MONAP, NAF, NAP-1, NAP1	interleukin 8	C00003375
3624	INHBA, EDF, FRP	inhibin, beta A	C00003375
83729	INHBE	inhibin, beta E	C00003375
3783	KCNN4, IK1, IKCA1, KCA4, KCa3.1, SK4, hIKCa1, hKCa4, hSK4	potassium intermediate/small conductance calcium-activated channel, subfamily N, member 4	C00003375
115207	KCTD12, C13orf2, PFET1, PFETIN	potassium channel tetramerization domain containing 12	C00003375
56992	KIF15, HKLP2, KNSL7, NY-BR-62	kinesin family member 15	C00003375
9585	KIF20B, CT90, KRMP1, MPHOSPH1, MPP-1, MPP1	kinesin family member 20B	C00003375
11004	KIF2C, KNSL6, MCAK	kinesin family member 2C	C00003375
3853	KRT6A, CK6A, CK6C, CK6D, K6A, K6C, K6D, KRT6C, KRT6D	keratin 6A	C00003375
3856	KRT8, CARD2, CK-8, CK8, CYK8, K2C8, K8, KO	keratin 8	C00003375
3934	LCN2, 24p3, MSFI, NGAL	lipocalin 2	C00003375
3998	LMAN1, ERGIC-53, ERGIC53, F5F8D, FMFD1, MCFD1, MR60, gp58	lectin, mannose-binding, 1	C00003375
4069	LYZ, LZM	lysozyme (EC:3.2.1.17)	C00003375
23499	MACF1, ABP620, ACF7, MACF, OFC4	microtubule-actin crosslinking factor 1	C00003375
5607	MAP2K5, HsT17454, MAPKK5, MEK5, PRKMK5	mitogen-activated protein kinase kinase 5 (EC:2.7.12.2)	C00003375
5594	MAPK1, ERK, ERK2, ERT1, MAPK2, P42MAPK, PRKM1, PRKM2, p38, p40, p41, p41mapk	mitogen-activated protein kinase 1 (EC:2.7.11.24)	C00003375
5595	MAPK3, ERK-1, ERK1, ERT2, HS44KDAP, HUMKER1A, P44ERK1, P44MAPK, PRKM3, p44-ERK1, p44-MAPK	mitogen-activated protein kinase 3 (EC:2.7.11.24)	C00003375
4149	MAX, bHLHd4	MYC associated factor X	C00003375
4170	MCL1, BCL2L3, EAT, MCL1-ES, MCL1L, MCL1S, Mcl-1, TM, bcl2-L-3, mcl1/EAT	myeloid cell leukemia sequence 1 (BCL2-related)	C00003375
4176	MCM7, CDC47, MCM2, P1.1-MCM3, P1CDC47, P85MCM, PNAS146	minichromosome maintenance complex component 7 (EC:3.6.4.12)	C00003375
55669	MFN1, hfzo1, hfzo2	mitofusin 1	C00003375
84311	MRPL45, L45mt, MRP-L45	mitochondrial ribosomal protein L45	C00003375
92399	MRRF, MRFF, MTRRF, RRF	mitochondrial ribosome recycling factor	C00003375
4489	MT1A, MT1, MT1S, MTC	metallothionein 1A	C00003375
4609	MYC, MRTL, MYCC, bHLHe39, c-Myc	v-myc avian myelocytomatosis viral oncogene homolog	C00003375
4666	NACA, NACA1	nascent polypeptide-associated complex alpha subunit (EC:5.3.99.3)	C00003375
4772	NFATC1, NF-ATC, NFAT2, NFATc	nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1	C00003375
4780	NFE2L2, NRF2	nuclear factor, erythroid 2-like 2	C00003375
4929	NR4A2, HZF-3, NOT, NURR1, RNR1, TINUR	nuclear receptor subfamily 4, group A, member 2	C00003375
26471	NUPR1, COM1, P8	nuclear protein, transcriptional regulator, 1	C00003375
142	PARP1, ADPRT, ADPRT_1, ADPRT1, ARTD1, PARP, PARP-1, PPOL, pADPRT-1	poly (ADP-ribose) polymerase 1 (EC:2.4.2.30)	C00003375
5106	PCK2, PEPCK, PEPCK-M, PEPCK2	phosphoenolpyruvate carboxykinase 2 (mitochondrial) (EC:4.1.1.32)	C00003375
11235	PDCD10, CCM3, TFAR15	programmed cell death 10	C00003375
10015	PDCD6IP, AIP1, ALIX, DRIP4, HP95	programmed cell death 6 interacting protein	C00003375
2923	PDIA3, ER60, ERp57, ERp60, ERp61, GRP57, GRP58, HsT17083, P58, PI-PLC	protein disulfide isomerase family A, member 3 (EC:5.3.4.1)	C00003375
5187	PER1, PER, RIGUI, hPER	period circadian clock 1	C00003375
5347	PLK1, PLK, STPK13	polo-like kinase 1 (EC:2.7.11.21)	C00003375
10733	PLK4, SAK, STK18	polo-like kinase 4 (EC:2.7.11.21)	C00003375
8985	PLOD3, LH3	procollagen-lysine, 2-oxoglutarate 5-dioxygenase 3 (EC:1.14.11.4)	C00003375
5366	PMAIP1, APR, NOXA	phorbol-12-myristate-13-acetate-induced protein 1	C00003375
23645	PPP1R15A, GADD34	protein phosphatase 1, regulatory subunit 15A	C00003375
5530	PPP3CA, CALN, CALNA, CALNA1, CCN1, CNA1, PPP2B	protein phosphatase 3, catalytic subunit, alpha isozyme (EC:3.1.3.16)	C00003375
25824	PRDX5, ACR1, AOEB166, B166, PLP, PMP20, PRDX6, PRXV, prx-V	peroxiredoxin 5 (EC:1.11.1.15)	C00003375
5579	PRKCB, PKC-beta, PKCB, PRKCB1, PRKCB2	protein kinase C, beta (EC:2.7.11.13)	C00003375
5743	PTGS2, COX-2, COX2, GRIPGHS, PGG/HS, PGHS-2, PHS-2, hCox-2	prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) (EC:1.14.99.1)	C00003375
5806	PTX3, TNFAIP5, TSG-14	pentraxin 3, long	C00003375
5955	RCN2, E6BP, ERC-55, ERC55, TCBP49	reticulocalbin 2, EF-hand calcium binding domain	C00003375
6284	S100A13	S100 calcium binding protein A13	C00003375
51435	SCARA3, APC7, CSR, CSR1, MSLR1, MSRL1	scavenger receptor class A, member 3	C00003375
23256	SCFD1, C14orf163, RA410, SLY1, SLY1P, STXBP1L2	sec1 family domain containing 1	C00003375
6326	SCN2A, BFIC3, BFIS3, BFNIS, EIEE11, HBA, HBSCI, HBSCII, NAC2, Na(v)1.2, Nav1.2, SCN2A1, SCN2A2	sodium channel, voltage-gated, type II, alpha subunit	C00003375
5265	SERPINA1, A1A, A1AT, AAT, PI, PI1, PRO2275, alpha1AT	serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1	C00003375
5055	SERPINB2, HsT1201, PAI, PAI-2, PAI2, PLANH2	serpin peptidase inhibitor, clade B (ovalbumin), member 2	C00003375
6418	SET, 2PP2A, I2PP2A, IGAAD, IPP2A2, PHAPII, TAF-I, TAF-IBETA	SET nuclear oncogene	C00003375
119559	SFXN4, BCRM1	sideroflexin 4	C00003375
6786	STIM1, D11S4896E, GOK, IMD10, TAM	stromal interaction molecule 1	C00003375
202374	STK32A, YANK1	serine/threonine kinase 32A (EC:2.7.11.1)	C00003375
10492	SYNCRIP, GRY-RBP, GRYRBP, HNRNPQ, HNRPQ1, NSAP1, PP68, hnRNP-Q	synaptotagmin binding, cytoplasmic RNA interacting protein	C00003375
7052	TGM2, G-ALPHA-h, GNAH, TG2, TGC	transglutaminase 2 (EC:2.3.2.13)	C00003375
10469	TIMM44, TIM44	translocase of inner mitochondrial membrane 44 homolog (yeast)	C00003375
7124	TNF, DIF, TNF-alpha, TNFA, TNFSF2	tumor necrosis factor	C00003375
7157	TP53, BCC7, LFS1, P53, TRP53	tumor protein p53	C00003375
7222	TRPC3, TRP3	transient receptor potential cation channel, subfamily C, member 3	C00003375
7272	TTK, CT96, ESK, MPH1, MPS1, MPS1L1, PYT	TTK protein kinase (EC:2.7.12.1)	C00003375
203068	TUBB, M40, OK/SW-cl.56, TUBB1, TUBB5	tubulin, beta class I	C00003375
10190	TXNDC9, APACD, PHLP3	thioredoxin domain containing 9	C00003375
11065	UBE2C, UBCH10, dJ447F3.2	ubiquitin-conjugating enzyme E2C (EC:6.3.2.19)	C00003375
7422	VEGFA, MVCD1, VEGF, VPF	vascular endothelial growth factor A	C00003375
7494	XBP1, TREB5, XBP-1, XBP2	X-box binding protein 1	C00003375
331	XIAP, API3, BIRC4, IAP-3, ILP1, MIHA, XLP2, hIAP-3, hIAP3	X-linked inhibitor of apoptosis	C00003375
7531	YWHAE, 14-3-3E, KCIP-1, MDCR, MDS	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide	C00003375

Related Diseases

Diseases related to proteins in ChEMBL interactions