Organism name | Thapsia garganica |
---|---|
Genus | Thapsia |
Family | Apiaceae |
Kingdom | Plantae |
Linked NCBI taxonomy name | Thapsia garganica |
---|---|
Linked NCBI taxonomy ID | 79022 |
Linked level | species |
Family in NCBI taxonomy | Apiaceae |
---|---|
ID | 4037 |
Kingdom (Superkingdom) in NCBI taxonomy | Viridiplantae |
---|---|
ID | 33090 |
Plant class | asterids |
---|---|
ID | 71274 |
KNApSAcK ID | name | ChEMBL link | CTD link |
# of proteins in
ChEMBL interaction / related OMIM / related KEGG DISEASE |
# of genes in
CTD interaction / related diseases |
KCF-S
cluster |
phytochemical
cluster |
figure |
---|---|---|---|---|---|---|---|---|
C00035137 |
Neohelmanthicin D
/ (-)-Neohelmanthicin D |
No. 1913 | ||||||
C00035136 |
Neohelmanthicin C
|
No. 1913 | ||||||
C00035135 |
Neohelmanthicin B
|
No. 1913 | ||||||
C00035134 |
Neohelmanthicin A
/ (-)-Neohelmanthicin A |
No. 1913 | ||||||
C00020716 |
Thapsivillosin K
|
No. 2100 | No. 38 | |||||
C00020715 |
Thapsigargicin
|
CHEMBL328508
CHEMBL1537509 |
C046319
|
16 / 11 / 9 | No. 2100 | No. 38 | ||
C00003375 |
Thapsigargin
|
CHEMBL96926
CHEMBL192566 CHEMBL1355952 |
D019284
|
45 / 52 / 75 | 157 / 0 | No. 2100 | No. 38 |
accession | description | class description | KNApSAcK metabolite in interactions |
# of diseases
(OMIM / KEGG) |
---|---|---|---|---|
P06746 | DNA polymerase beta | Enzyme | C00003375 C00020715 | 0 / 0 |
P10636 | Microtubule-associated protein tau | Unclassified protein | C00003375 C00020715 | 4 / 3 |
P27695 | DNA-(apurinic or apyrimidinic site) lyase | Enzyme | C00003375 C00020715 | 0 / 0 |
Q6W5P4 | Neuropeptide S receptor | Neuropeptide receptor | C00003375 C00020715 | 1 / 0 |
Q96QE3 | ATPase family AAA domain-containing protein 5 | Unclassified protein | C00003375 C00020715 | 0 / 0 |
O15118 | Niemann-Pick C1 protein | Unclassified protein | C00003375 C00020715 | 1 / 1 |
P28482 | Mitogen-activated protein kinase 1 | Erk | C00003375 C00020715 | 0 / 0 |
P06280 | Alpha-galactosidase A | Enzyme | C00003375 C00020715 | 1 / 1 |
Q03164 | Histone-lysine N-methyltransferase 2A | Enzyme | C00003375 C00020715 | 1 / 2 |
P51151 | Ras-related protein Rab-9A | Unclassified protein | C00003375 C00020715 | 0 / 0 |
O14983 | Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 | Calcium | C00003375 C00020715 | 1 / 1 |
P83916 | Chromobox protein homolog 1 | Unclassified protein | C00003375 | 0 / 0 |
P02545 | Prelamin-A/C | Unclassified protein | C00003375 | 11 / 10 |
P16473 | Thyrotropin receptor | Glycohormone receptor | C00003375 | 3 / 2 |
P10253 | Lysosomal alpha-glucosidase | Hydrolase | C00003375 | 1 / 1 |
P11712 | Cytochrome P450 2C9 | Cytochrome P450 2C9 | C00003375 | 0 / 1 |
P54132 | Bloom syndrome protein | Enzyme | C00003375 | 1 / 2 |
P00352 | Retinal dehydrogenase 1 | Enzyme | C00003375 | 0 / 0 |
Q16665 | Hypoxia-inducible factor 1-alpha | Transcription Factor | C00003375 | 0 / 0 |
Q92830 | Histone acetyltransferase KAT2A | Enzyme | C00020715 | 0 / 0 |
P42858 | Huntingtin | Unclassified protein | C00020715 | 1 / 1 |
O75496 | Geminin | Unclassified protein | C00003375 | 0 / 0 |
P10635 | Cytochrome P450 2D6 | Cytochrome P450 2D6 | C00003375 | 1 / 0 |
Q9Y253 | DNA polymerase eta | Enzyme | C00003375 | 1 / 1 |
Q12809 | Potassium voltage-gated channel subfamily H member 2 | KCNH, Kv10-12.x (Ether-a-go-go) | C00003375 | 2 / 2 |
Q13526 | Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 | Enzyme | C00003375 | 0 / 0 |
P11021 | 78 kDa glucose-regulated protein | Unclassified protein | C00003375 | 0 / 0 |
O94782 | Ubiquitin carboxyl-terminal hydrolase 1 | Enzyme | C00003375 | 0 / 0 |
P21728 | D(1A) dopamine receptor | Dopamine receptor | C00003375 | 0 / 0 |
Q99700 | Ataxin-2 | Unclassified protein | C00003375 | 1 / 1 |
P05177 | Cytochrome P450 1A2 | Cytochrome P450 1A2 | C00003375 | 0 / 0 |
P15428 | 15-hydroxyprostaglandin dehydrogenase [NAD(+)] | Enzyme | C00003375 | 2 / 2 |
Q9UIF8 | Bromodomain adjacent to zinc finger domain protein 2B | Unclassified protein | C00020715 | 0 / 0 |
Q01453 | Peripheral myelin protein 22 | Unclassified protein | C00003375 | 5 / 2 |
P17861 | X-box-binding protein 1 | Unclassified protein | C00020715 | 1 / 0 |
P19838 | Nuclear factor NF-kappa-B p105 subunit | Transcription Factor | C00003375 | 0 / 0 |
P16050 | Arachidonate 15-lipoxygenase | Enzyme | C00003375 | 0 / 0 |
P33261 | Cytochrome P450 2C19 | Cytochrome P450 2C19 | C00003375 | 1 / 1 |
P08684 | Cytochrome P450 3A4 | Cytochrome P450 3A4 | C00003375 | 0 / 1 |
Q9UNA4 | DNA polymerase iota | Enzyme | C00003375 | 0 / 0 |
Q16637 | Survival motor neuron protein | Unclassified protein | C00003375 | 4 / 1 |
P04637 | Cellular tumor antigen p53 | Transcription Factor | C00003375 | 7 / 37 |
P42345 | Serine/threonine-protein kinase mTOR | Enzyme | C00003375 | 0 / 0 |
Q99549 | M-phase phosphoprotein 8 | Unclassified protein | C00003375 | 0 / 0 |
Q16236 | Nuclear factor erythroid 2-related factor 2 | Unclassified protein | C00003375 | 0 / 0 |
Q9UBT6 | DNA polymerase kappa | Enzyme | C00003375 | 0 / 0 |
P46063 | ATP-dependent DNA helicase Q1 | Enzyme | C00020715 | 0 / 0 |
P40225 | Thrombopoietin | Unclassified protein | C00003375 | 1 / 1 |
Q96KQ7 | Histone-lysine N-methyltransferase EHMT2 | Enzyme | C00003375 | 0 / 0 |
O00255 | Menin | Unclassified protein | C00003375 | 2 / 5 |
gene | gene name | gene description | KNApSAcK metabolite in interactions |
---|---|---|---|
133 | ADM, AM | adrenomedullin |
C00003375
|
150 | ADRA2A, ADRA2, ADRA2R, ADRAR, ALPHA2AAR, ZNF32 | adrenoceptor alpha 2A |
C00003375
|
79026 | AHNAK, AHNAKRS | AHNAK nucleoprotein |
C00003375
|
207 | AKT1, AKT, CWS6, PKB, PKB-ALPHA, PRKBA, RAC, RAC-ALPHA | v-akt murine thymoma viral oncogene homolog 1 (EC:2.7.11.1) |
C00003375
|
240 | ALOX5, 5-LO, 5-LOX, 5LPG, LOG5 | arachidonate 5-lipoxygenase (EC:1.13.11.34) |
C00003375
|
467 | ATF3 | activating transcription factor 3 |
C00003375
|
468 | ATF4, CREB-2, CREB2, TAXREB67, TXREB | activating transcription factor 4 |
C00003375
|
22926 | ATF6, ATF6A | activating transcription factor 6 |
C00003375
|
488 | ATP2A2, ATP2B, DAR, DD, SERCA2 | ATPase, Ca++ transporting, cardiac muscle, slow twitch 2 (EC:3.6.3.8) |
C00003375
|
489 | ATP2A3, SERCA3 | ATPase, Ca++ transporting, ubiquitous (EC:3.6.3.8) |
C00003375
|
245972 | ATP6V0D2, ATP6D2, VMA6 | ATPase, H+ transporting, lysosomal 38kDa, V0 subunit d2 (EC:3.6.3.14) |
C00003375
|
581 | BAX, BCL2L4 | BCL2-associated X protein |
C00003375
|
10282 | BET1, HBET1 | Bet1 golgi vesicular membrane trafficking protein |
C00003375
|
329 | BIRC2, API1, HIAP2, Hiap-2, MIHB, RNF48, c-IAP1, cIAP1 | baculoviral IAP repeat containing 2 |
C00003375
|
330 | BIRC3, AIP1, API2, CIAP2, HAIP1, HIAP1, MALT2, MIHC, RNF49, c-IAP2 | baculoviral IAP repeat containing 3 |
C00003375
|
672 | BRCA1, BRCAI, BRCC1, BROVCA1, IRIS, PNCA4, PPP1R53, PSCP, RNF53 | breast cancer 1, early onset |
C00003375
|
675 | BRCA2, BRCC2, BROVCA2, FACD, FAD, FAD1, FANCB, FANCD, FANCD1, GLM3, PNCA2 | breast cancer 2, early onset |
C00003375
|
773 | CACNA1A, APCA, BI, CACNL1A4, CAV2.1, EA2, FHM, HPCA, MHP, MHP1, SCA6 | calcium channel, voltage-dependent, P/Q type, alpha 1A subunit |
C00003375
|
796 | CALCA, CALC1, CGRP, CGRP-I, CGRP1, CT, KC | calcitonin-related polypeptide alpha |
C00003375
|
811 | CALR, CRT, RO, SSA, cC1qR | calreticulin |
C00003375
|
813 | CALU | calumenin |
C00003375
|
821 | CANX, CNX, IP90, P90 | calnexin |
C00003375
|
100506742 | CASP12, CASP-12, CASP12P1 | caspase 12 (gene/pseudogene) |
C00003375
|
835 | CASP2, CASP-2, ICH1, NEDD-2, NEDD2, PPP1R57 | caspase 2, apoptosis-related cysteine peptidase (EC:3.4.22.55) |
C00003375
|
836 | CASP3, CPP32, CPP32B, SCA-1 | caspase 3, apoptosis-related cysteine peptidase (EC:3.4.22.56) |
C00003375
|
837 | CASP4, ICE(rel)II, ICEREL-II, ICH-2, Mih1/TX, TX | caspase 4, apoptosis-related cysteine peptidase (EC:3.4.22.57) |
C00003375
|
840 | CASP7, CASP-7, CMH-1, ICE-LAP3, LICE2, MCH3 | caspase 7, apoptosis-related cysteine peptidase (EC:3.4.22.60) |
C00003375
|
842 | CASP9, APAF-3, APAF3, ICE-LAP6, MCH6, PPP1R56 | caspase 9, apoptosis-related cysteine peptidase (EC:3.4.22.62) |
C00003375
|
117155 | CATSPER2 | cation channel, sperm associated 2 |
C00003375
|
6347 | CCL2, GDCF-2, HC11, HSMCR30, MCAF, MCP-1, MCP1, SCYA2, SMC-CF | chemokine (C-C motif) ligand 2 |
C00003375
|
595 | CCND1, BCL1, D11S287E, PRAD1, U21B31 | cyclin D1 |
C00003375
|
901 | CCNG2 | cyclin G2 |
C00003375
|
991 | CDC20, CDC20A, bA276H19.3, p55CDC | cell division cycle 20 |
C00003375
|
1017 | CDK2, p33(CDK2) | cyclin-dependent kinase 2 (EC:2.7.11.22) |
C00003375
|
1063 | CENPF, CENF, PRO1779, hcp-1 | centromere protein F, 350/400kDa |
C00003375
|
1080 | CFTR, ABC35, ABCC7, CF, CFTR/MRP, MRP7, TNR-CFTR, dJ760C5.1 | cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7) (EC:3.6.3.49) |
C00003375
|
1081 | CGA, CG-ALPHA, FSHA, GPHA1, GPHa, HCG, LHA, TSHA | glycoprotein hormones, alpha polypeptide |
C00003375
|
79094 | CHAC1 | ChaC, cation transport regulator homolog 1 (E. coli) |
C00003375
|
10036 | CHAF1A, CAF-1, CAF1, CAF1B, CAF1P150, P150 | chromatin assembly factor 1, subunit A (p150) |
C00003375
|
1152 | CKB, B-CK, CKBB | creatine kinase, brain (EC:2.7.3.2) |
C00003375
|
6320 | CLEC11A, CLECSF3, LSLCL, P47, SCGF | C-type lectin domain family 11, member A |
C00003375
|
1293 | COL6A3 | collagen, type VI, alpha 3 |
C00003375
|
51138 | COPS4, CSN4 | COP9 signalosome subunit 4 |
C00003375
|
8904 | CPNE1, COPN1, CPN1 | copine I |
C00003375
|
90993 | CREB3L1, OASIS | cAMP responsive element binding protein 3-like 1 |
C00003375
|
1429 | CRYZ | crystallin, zeta (quinone reductase) (EC:1.6.5.5) |
C00003375
|
1489 | CTF1, CT-1, CT1 | cardiotrophin 1 |
C00003375
|
2920 | CXCL2, CINC-2a, GRO2, GROb, MGSA-b, MIP-2a, MIP2, MIP2A, SCYB2 | chemokine (C-X-C motif) ligand 2 |
C00003375
|
4051 | CYP4F3, CPF3, CYP4F, LTB4H | cytochrome P450, family 4, subfamily F, polypeptide 3 (EC:1.14.13.30) |
C00003375
|
1611 | DAP | death-associated protein |
C00003375
|
1649 | DDIT3, CEBPZ, CHOP, CHOP-10, CHOP10, GADD153 | DNA-damage-inducible transcript 3 |
C00003375
|
56616 | DIABLO, DFNA64, SMAC | diablo, IAP-binding mitochondrial protein |
C00003375
|
51726 | DNAJB11, ABBP-2, ABBP2, DJ9, Dj-9, EDJ, ERdj3, ERj3, ERj3p, PRO1080, UNQ537, hDj-9 | DnaJ (Hsp40) homolog, subfamily B, member 11 |
C00003375
|
4189 | DNAJB9, ERdj4, MDG-1, MDG1, MST049, MSTP049 | DnaJ (Hsp40) homolog, subfamily B, member 9 |
C00003375
|
54431 | DNAJC10, ERdj5, JPDI, MTHr, PDIA19 | DnaJ (Hsp40) homolog, subfamily C, member 10 |
C00003375
|
5611 | DNAJC3, ERdj6, HP58, P58, P58IPK, PRKRI | DnaJ (Hsp40) homolog, subfamily C, member 3 |
C00003375
|
10570 | DPYSL4, CRMP3, DRP-4, ULIP4 | dihydropyrimidinase-like 4 |
C00003375
|
1950 | EGF, HOMG4, URG | epidermal growth factor |
C00003375
|
1958 | EGR1, AT225, G0S30, KROX-24, NGFI-A, TIS8, ZIF-268, ZNF225 | early growth response 1 |
C00003375
|
83939 | EIF2A, EIF-2A, MST089, MSTP004, MSTP089 | eukaryotic translation initiation factor 2A, 65kDa |
C00003375
|
9451 | EIF2AK3, PEK, PERK, WRS | eukaryotic translation initiation factor 2-alpha kinase 3 (EC:2.7.11.1) |
C00003375
|
1965 | EIF2S1, EIF-2, EIF-2A, EIF-2alpha, EIF2, EIF2A | eukaryotic translation initiation factor 2, subunit 1 alpha, 35kDa |
C00003375
|
8668 | EIF3I, EIF3S2, PRO2242, TRIP-1, TRIP1, eIF3-beta, eIF3-p36 | eukaryotic translation initiation factor 3, subunit I |
C00003375
|
1984 | EIF5A, EIF-5A, EIF5A1, eIF5AI | eukaryotic translation initiation factor 5A |
C00003375
|
63916 | ELMO2, CED-12, CED12, ELMO-2 | engulfment and cell motility 2 |
C00003375
|
2077 | ERF, CRS4, PE-2, PE2 | Ets2 repressor factor |
C00003375
|
2081 | ERN1, IRE1, IRE1P, IRE1a, hIRE1p | endoplasmic reticulum to nucleus signaling 1 (EC:2.7.11.1) |
C00003375
|
2258 | FGF13, FGF-13, FGF2, FHF-2, FHF2 | fibroblast growth factor 13 |
C00003375
|
23768 | FLRT2 | fibronectin leucine rich transmembrane protein 2 |
C00003375
|
2324 | FLT4, FLT41, LMPH1A, PCL, VEGFR3 | fms-related tyrosine kinase 4 (EC:2.7.10.1) |
C00003375
|
2353 | FOS, AP-1, C-FOS, p55 | FBJ murine osteosarcoma viral oncogene homolog |
C00003375
|
2354 | FOSB, AP-1, G0S3, GOS3, GOSB | FBJ murine osteosarcoma viral oncogene homolog B |
C00003375
|
1647 | GADD45A, DDIT1, GADD45 | growth arrest and DNA-damage-inducible, alpha |
C00003375
|
2669 | GEM, KIR | GTP binding protein overexpressed in skeletal muscle |
C00003375
|
9527 | GOSR1, GOLIM2, GOS-28, GOS28, GOS28/P28, GS28, P28 | golgi SNAP receptor complex member 1 |
C00003375
|
2936 | GSR | glutathione reductase (EC:1.8.1.7) |
C00003375
|
3014 | H2AFX, H2A.X, H2A/X, H2AX | H2A histone family, member X |
C00003375
|
3068 | HDGF, HMG1L2 | hepatoma-derived growth factor |
C00003375
|
3099 | HK2, HKII, HXK2 | hexokinase 2 (EC:2.7.1.1) |
C00003375
|
7184 | HSP90B1, ECGP, GP96, GRP94, TRA1 | heat shock protein 90kDa beta (Grp94), member 1 |
C00003375
|
3309 | HSPA5, BIP, GRP78, MIF2 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) |
C00003375
|
3313 | HSPA9, CSA, GRP-75, GRP75, HSPA9B, MOT, MOT2, MTHSP75, PBP74 | heat shock 70kDa protein 9 (mortalin) |
C00003375
|
3336 | HSPE1, CPN10, EPF, GROES, HSP10 | heat shock 10kDa protein 1 |
C00003375
|
3350 | HTR1A, 5-HT-1A, 5-HT1A, 5HT1a, ADRB2RL1, ADRBRL1, G-21, PFMCD | 5-hydroxytryptamine (serotonin) receptor 1A, G protein-coupled |
C00003375
|
50615 | IL21R, CD360, NILR | interleukin 21 receptor |
C00003375
|
3569 | IL6, BSF2, HGF, HSF, IFNB2, IL-6 | interleukin 6 (interferon, beta 2) |
C00003375
|
3576 | IL8, CXCL8, GCP-1, GCP1, LECT, LUCT, LYNAP, MDNCF, MONAP, NAF, NAP-1, NAP1 | interleukin 8 |
C00003375
|
3624 | INHBA, EDF, FRP | inhibin, beta A |
C00003375
|
83729 | INHBE | inhibin, beta E |
C00003375
|
3783 | KCNN4, IK1, IKCA1, KCA4, KCa3.1, SK4, hIKCa1, hKCa4, hSK4 | potassium intermediate/small conductance calcium-activated channel, subfamily N, member 4 |
C00003375
|
115207 | KCTD12, C13orf2, PFET1, PFETIN | potassium channel tetramerization domain containing 12 |
C00003375
|
56992 | KIF15, HKLP2, KNSL7, NY-BR-62 | kinesin family member 15 |
C00003375
|
9585 | KIF20B, CT90, KRMP1, MPHOSPH1, MPP-1, MPP1 | kinesin family member 20B |
C00003375
|
11004 | KIF2C, KNSL6, MCAK | kinesin family member 2C |
C00003375
|
3853 | KRT6A, CK6A, CK6C, CK6D, K6A, K6C, K6D, KRT6C, KRT6D | keratin 6A |
C00003375
|
3856 | KRT8, CARD2, CK-8, CK8, CYK8, K2C8, K8, KO | keratin 8 |
C00003375
|
3934 | LCN2, 24p3, MSFI, NGAL | lipocalin 2 |
C00003375
|
3998 | LMAN1, ERGIC-53, ERGIC53, F5F8D, FMFD1, MCFD1, MR60, gp58 | lectin, mannose-binding, 1 |
C00003375
|
4069 | LYZ, LZM | lysozyme (EC:3.2.1.17) |
C00003375
|
23499 | MACF1, ABP620, ACF7, MACF, OFC4 | microtubule-actin crosslinking factor 1 |
C00003375
|
5607 | MAP2K5, HsT17454, MAPKK5, MEK5, PRKMK5 | mitogen-activated protein kinase kinase 5 (EC:2.7.12.2) |
C00003375
|
5594 | MAPK1, ERK, ERK2, ERT1, MAPK2, P42MAPK, PRKM1, PRKM2, p38, p40, p41, p41mapk | mitogen-activated protein kinase 1 (EC:2.7.11.24) |
C00003375
|
5595 | MAPK3, ERK-1, ERK1, ERT2, HS44KDAP, HUMKER1A, P44ERK1, P44MAPK, PRKM3, p44-ERK1, p44-MAPK | mitogen-activated protein kinase 3 (EC:2.7.11.24) |
C00003375
|
4149 | MAX, bHLHd4 | MYC associated factor X |
C00003375
|
4170 | MCL1, BCL2L3, EAT, MCL1-ES, MCL1L, MCL1S, Mcl-1, TM, bcl2-L-3, mcl1/EAT | myeloid cell leukemia sequence 1 (BCL2-related) |
C00003375
|
4176 | MCM7, CDC47, MCM2, P1.1-MCM3, P1CDC47, P85MCM, PNAS146 | minichromosome maintenance complex component 7 (EC:3.6.4.12) |
C00003375
|
55669 | MFN1, hfzo1, hfzo2 | mitofusin 1 |
C00003375
|
84311 | MRPL45, L45mt, MRP-L45 | mitochondrial ribosomal protein L45 |
C00003375
|
92399 | MRRF, MRFF, MTRRF, RRF | mitochondrial ribosome recycling factor |
C00003375
|
4489 | MT1A, MT1, MT1S, MTC | metallothionein 1A |
C00003375
|
4609 | MYC, MRTL, MYCC, bHLHe39, c-Myc | v-myc avian myelocytomatosis viral oncogene homolog |
C00003375
|
4666 | NACA, NACA1 | nascent polypeptide-associated complex alpha subunit (EC:5.3.99.3) |
C00003375
|
4772 | NFATC1, NF-ATC, NFAT2, NFATc | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1 |
C00003375
|
4780 | NFE2L2, NRF2 | nuclear factor, erythroid 2-like 2 |
C00003375
|
4929 | NR4A2, HZF-3, NOT, NURR1, RNR1, TINUR | nuclear receptor subfamily 4, group A, member 2 |
C00003375
|
26471 | NUPR1, COM1, P8 | nuclear protein, transcriptional regulator, 1 |
C00003375
|
142 | PARP1, ADPRT, ADPRT_1, ADPRT1, ARTD1, PARP, PARP-1, PPOL, pADPRT-1 | poly (ADP-ribose) polymerase 1 (EC:2.4.2.30) |
C00003375
|
5106 | PCK2, PEPCK, PEPCK-M, PEPCK2 | phosphoenolpyruvate carboxykinase 2 (mitochondrial) (EC:4.1.1.32) |
C00003375
|
11235 | PDCD10, CCM3, TFAR15 | programmed cell death 10 |
C00003375
|
10015 | PDCD6IP, AIP1, ALIX, DRIP4, HP95 | programmed cell death 6 interacting protein |
C00003375
|
2923 | PDIA3, ER60, ERp57, ERp60, ERp61, GRP57, GRP58, HsT17083, P58, PI-PLC | protein disulfide isomerase family A, member 3 (EC:5.3.4.1) |
C00003375
|
5187 | PER1, PER, RIGUI, hPER | period circadian clock 1 |
C00003375
|
5347 | PLK1, PLK, STPK13 | polo-like kinase 1 (EC:2.7.11.21) |
C00003375
|
10733 | PLK4, SAK, STK18 | polo-like kinase 4 (EC:2.7.11.21) |
C00003375
|
8985 | PLOD3, LH3 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 3 (EC:1.14.11.4) |
C00003375
|
5366 | PMAIP1, APR, NOXA | phorbol-12-myristate-13-acetate-induced protein 1 |
C00003375
|
23645 | PPP1R15A, GADD34 | protein phosphatase 1, regulatory subunit 15A |
C00003375
|
5530 | PPP3CA, CALN, CALNA, CALNA1, CCN1, CNA1, PPP2B | protein phosphatase 3, catalytic subunit, alpha isozyme (EC:3.1.3.16) |
C00003375
|
25824 | PRDX5, ACR1, AOEB166, B166, PLP, PMP20, PRDX6, PRXV, prx-V | peroxiredoxin 5 (EC:1.11.1.15) |
C00003375
|
5579 | PRKCB, PKC-beta, PKCB, PRKCB1, PRKCB2 | protein kinase C, beta (EC:2.7.11.13) |
C00003375
|
5743 | PTGS2, COX-2, COX2, GRIPGHS, PGG/HS, PGHS-2, PHS-2, hCox-2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) (EC:1.14.99.1) |
C00003375
|
5806 | PTX3, TNFAIP5, TSG-14 | pentraxin 3, long |
C00003375
|
5955 | RCN2, E6BP, ERC-55, ERC55, TCBP49 | reticulocalbin 2, EF-hand calcium binding domain |
C00003375
|
6284 | S100A13 | S100 calcium binding protein A13 |
C00003375
|
51435 | SCARA3, APC7, CSR, CSR1, MSLR1, MSRL1 | scavenger receptor class A, member 3 |
C00003375
|
23256 | SCFD1, C14orf163, RA410, SLY1, SLY1P, STXBP1L2 | sec1 family domain containing 1 |
C00003375
|
6326 | SCN2A, BFIC3, BFIS3, BFNIS, EIEE11, HBA, HBSCI, HBSCII, NAC2, Na(v)1.2, Nav1.2, SCN2A1, SCN2A2 | sodium channel, voltage-gated, type II, alpha subunit |
C00003375
|
5265 | SERPINA1, A1A, A1AT, AAT, PI, PI1, PRO2275, alpha1AT | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 |
C00003375
|
5055 | SERPINB2, HsT1201, PAI, PAI-2, PAI2, PLANH2 | serpin peptidase inhibitor, clade B (ovalbumin), member 2 |
C00003375
|
6418 | SET, 2PP2A, I2PP2A, IGAAD, IPP2A2, PHAPII, TAF-I, TAF-IBETA | SET nuclear oncogene |
C00003375
|
119559 | SFXN4, BCRM1 | sideroflexin 4 |
C00003375
|
6786 | STIM1, D11S4896E, GOK, IMD10, TAM | stromal interaction molecule 1 |
C00003375
|
202374 | STK32A, YANK1 | serine/threonine kinase 32A (EC:2.7.11.1) |
C00003375
|
10492 | SYNCRIP, GRY-RBP, GRYRBP, HNRNPQ, HNRPQ1, NSAP1, PP68, hnRNP-Q | synaptotagmin binding, cytoplasmic RNA interacting protein |
C00003375
|
7052 | TGM2, G-ALPHA-h, GNAH, TG2, TGC | transglutaminase 2 (EC:2.3.2.13) |
C00003375
|
10469 | TIMM44, TIM44 | translocase of inner mitochondrial membrane 44 homolog (yeast) |
C00003375
|
7124 | TNF, DIF, TNF-alpha, TNFA, TNFSF2 | tumor necrosis factor |
C00003375
|
7157 | TP53, BCC7, LFS1, P53, TRP53 | tumor protein p53 |
C00003375
|
7222 | TRPC3, TRP3 | transient receptor potential cation channel, subfamily C, member 3 |
C00003375
|
7272 | TTK, CT96, ESK, MPH1, MPS1, MPS1L1, PYT | TTK protein kinase (EC:2.7.12.1) |
C00003375
|
203068 | TUBB, M40, OK/SW-cl.56, TUBB1, TUBB5 | tubulin, beta class I |
C00003375
|
10190 | TXNDC9, APACD, PHLP3 | thioredoxin domain containing 9 |
C00003375
|
11065 | UBE2C, UBCH10, dJ447F3.2 | ubiquitin-conjugating enzyme E2C (EC:6.3.2.19) |
C00003375
|
7422 | VEGFA, MVCD1, VEGF, VPF | vascular endothelial growth factor A |
C00003375
|
7494 | XBP1, TREB5, XBP-1, XBP2 | X-box binding protein 1 |
C00003375
|
331 | XIAP, API3, BIRC4, IAP-3, ILP1, MIHA, XLP2, hIAP-3, hIAP3 | X-linked inhibitor of apoptosis |
C00003375
|
7531 | YWHAE, 14-3-3E, KCIP-1, MDCR, MDS | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide |
C00003375
|
OMIM | preferred title | UniProt |
---|---|---|
#202300 | Adrenocortical carcinoma, hereditary; adcc |
P04637
|
#608584 | Asthma-related traits, susceptibility to, 2 |
Q6W5P4
|
#614740 | Basal cell carcinoma, susceptibility to, 7; bcc7 |
P04637
|
#210900 | Bloom syndrome; blm |
P54132
|
#601003 | Brody myopathy |
O14983
|
#115200 | Cardiomyopathy, dilated, 1a; cmd1a |
P02545
|
#212112 | Cardiomyopathy, dilated, with hypergonadotropic hypogonadism |
P02545
|
#118300 | Charcot-marie-tooth disease and deafness |
Q01453
|
#605588 | Charcot-marie-tooth disease, axonal, type 2b1; cmt2b1 |
P02545
|
#118220 | Charcot-marie-tooth disease, demyelinating, type 1a; cmt1a |
Q01453
|
#119900 | Digital clubbing, isolated congenital |
P15428
|
#609535 | Drug metabolism, poor, cyp2c19-related |
P33261
|
#608902 | Drug metabolism, poor, cyp2d6-related |
P10635
|
#181350 | Emery-dreifuss muscular dystrophy 2, autosomal dominant; edmd2 |
P02545
|
#133239 | Esophageal cancer |
P04637
|
#301500 | Fabry disease |
P06280
|
#600274 | Frontotemporal dementia; ftd |
P10636
|
#232300 | Glycogen storage disease ii |
P10253
|
#139393 | Guillain-barre syndrome, familial; gbs |
Q01453
|
#605130 | Hairy elbows, short stature, facial dysmorphism, and developmental delay |
Q03164
|
#610140 | Heart-hand syndrome, slovenian type |
P02545
|
#143100 | Huntington disease; hd |
P42858
|
#176670 | Hutchinson-gilford progeria syndrome; hgps |
P02545
|
#145000 | Hyperparathyroidism 1; hrpt1 |
O00255
|
#603373 | Hyperthyroidism, familial gestational |
P16473
|
#609152 | Hyperthyroidism, nonautoimmune |
P16473
|
#145900 | Hypertrophic neuropathy of dejerine-sottas |
Q01453
|
#259100 | Hypertrophic osteoarthropathy, primary, autosomal recessive, 1; phoar1 |
P15428
|
#275200 | Hypothyroidism, congenital, nongoitrous, 1; chng1 |
P16473
|
#151623 | Li-fraumeni syndrome 1; lfs1 |
P04637
|
#151660 | Lipodystrophy, familial partial, type 2; fpld2 |
P02545
|
#613688 | Long qt syndrome 2; lqt2 |
Q12809
|
#211980 | Lung cancer |
P04637
|
#612371 | Major affective disorder 7; mafd7 |
P17861
|
#248370 | Mandibuloacral dysplasia with type a lipodystrophy; mada |
P02545
|
#131100 | Multiple endocrine neoplasia, type i; men1 |
O00255
|
#613205 | Muscular dystrophy, congenital, lmna-related |
P02545
|
#159001 | Muscular dystrophy, limb-girdle, type 1b; lgmd1b |
P02545
|
#162500 | Neuropathy, hereditary, with liability to pressure palsies; hnpp |
Q01453
|
#257220 | Niemann-pick disease, type c1; npc1 |
O15118
|
#260500 | Papilloma of choroid plexus; cpp |
P04637
|
#260540 | Parkinson-dementia syndrome |
P10636
|
#172700 | Pick disease of brain |
P10636
|
#275210 | Restrictive dermopathy, lethal |
P02545
|
#609620 | Short qt syndrome 1; sqt1 |
Q12809
|
#253300 | Spinal muscular atrophy, type i; sma1 |
Q16637
|
#253550 | Spinal muscular atrophy, type ii; sma2 |
Q16637
|
#253400 | Spinal muscular atrophy, type iii; sma3 |
Q16637
|
#271150 | Spinal muscular atrophy, type iv; sma4 |
Q16637
|
#183090 | Spinocerebellar ataxia 2; sca2 |
Q99700
|
#275355 | Squamous cell carcinoma, head and neck; hnscc |
P04637
|
#601104 | Supranuclear palsy, progressive, 1; psnp1 |
P10636
|
#187950 | Thrombocythemia 1; thcyt1 |
P40225
|
#278750 | Xeroderma pigmentosum, variant type; xpv |
Q9Y253
|
KEGG | name | UniProt |
---|---|---|
H00033 | Adrenal carcinoma |
O00255
(related)
P04637 (related) |
H00034 | Carcinoid |
O00255
(related)
|
H00045 | Malignant islet cell carcinoma |
O00255
(related)
|
H00246 | Primary hyperparathyroidism |
O00255
(related)
|
H01102 | Pituitary adenomas |
O00255
(related)
|
H01129 | Brody myopathy |
O14983
(related)
|
H00136 | Niemann-Pick disease type C (NPC) |
O15118
(related)
|
H00264 | Charcot-Marie-Tooth disease (CMT) |
P02545
(related)
Q01453 (related) |
H00294 | Dilated cardiomyopathy (DCM) |
P02545
(related)
|
H00420 | Familial partial lipodystrophy (FPL) |
P02545
(related)
|
H00563 | Emery-Dreifuss muscular dystrophy |
P02545
(related)
|
H00590 | Congenital muscular dystrophies (CMD/MDC) |
P02545
(related)
|
H00593 | Limb-girdle muscular dystrophy (LGMD) |
P02545
(related)
|
H00601 | Hutchinson-Gilford progeria syndrome |
P02545
(related)
|
H00663 | Restrictive dermopathy |
P02545
(related)
|
H00665 | Mandibuloacral dysplasia |
P02545
(related)
|
H01216 | Left ventricular noncompaction (LVNC) |
P02545
(related)
|
H00004 | Chronic myeloid leukemia (CML) |
P04637
(related)
|
H00005 | Chronic lymphocytic leukemia (CLL) |
P04637
(related)
|
H00006 | Hairy-cell leukemia |
P04637
(related)
|
H00008 | Burkitt lymphoma |
P04637
(related)
|
H00009 | Adult T-cell leukemia |
P04637
(related)
|
H00010 | Multiple myeloma |
P04637
(related)
|
H00013 | Small cell lung cancer |
P04637
(related)
|
H00014 | Non-small cell lung cancer |
P04637
(related)
|
H00015 | Malignant pleural mesothelioma |
P04637
(related)
|
H00016 | Oral cancer |
P04637
(related)
P04637 (marker) |
H00017 | Esophageal cancer |
P04637
(related)
P04637 (marker) |
H00018 | Gastric cancer |
P04637
(related)
|
H00019 | Pancreatic cancer |
P04637
(related)
P04637 (marker) |
H00020 | Colorectal cancer |
P04637
(related)
P04637 (marker) |
H00022 | Bladder cancer |
P04637
(related)
|
H00025 | Penile cancer |
P04637
(related)
P04637 (marker) |
H00026 | Endometrial Cancer |
P04637
(related)
|
H00027 | Ovarian cancer |
P04637
(related)
|
H00028 | Choriocarcinoma |
P04637
(related)
|
H00029 | Vulvar cancer |
P04637
(related)
|
H00031 | Breast cancer |
P04637
(related)
|
H00032 | Thyroid cancer |
P04637
(related)
|
H00036 | Osteosarcoma |
P04637
(related)
P08684 (marker) |
H00038 | Malignant melanoma |
P04637
(related)
|
H00039 | Basal cell carcinoma |
P04637
(related)
|
H00040 | Squamous cell carcinoma |
P04637
(related)
|
H00041 | Kaposi's sarcoma |
P04637
(related)
|
H00042 | Glioma |
P04637
(related)
P04637 (marker) |
H00044 | Cancer of the anal canal |
P04637
(related)
|
H00046 | Cholangiocarcinoma |
P04637
(related)
|
H00047 | Gallbladder cancer |
P04637
(related)
|
H00048 | Hepatocellular carcinoma |
P04637
(related)
|
H00055 | Laryngeal cancer |
P04637
(related)
P04637 (marker) |
H00881 | Li-Fraumeni syndrome |
P04637
(related)
|
H01007 | Choroid plexus papilloma |
P04637
(related)
|
H00021 | Renal cell carcinoma |
P04637
(marker)
|
H00125 | Fabry disease |
P06280
(related)
|
H00069 | Glycogen storage diseases (GSD) |
P10253
(related)
|
H00058 | Amyotrophic lateral sclerosis (ALS) |
P10636
(related)
|
H00077 | Progressive supranuclear palsy (PSP) |
P10636
(related)
|
H00078 | Frontotemporal lobar degeneration (FTLD) |
P10636
(related)
|
H01205 | Coumarin resistance |
P11712
(related)
|
H00457 | Primary hypertrophic osteoarthropathy (PHO) |
P15428
(related)
|
H01246 | Isolated congenital nail clubbing (ICNC) |
P15428
(related)
|
H00250 | Congenital nongoitrous hypothyroidism (CHNG) |
P16473
(related)
|
H01269 | Congenital hyperthyroidism |
P16473
(related)
|
H01171 | Poor drug metabolism (PM) |
P33261
(related)
|
H00227 | Congenital amegakaryocytic thrombocytopenia (CAMT) |
P40225
(marker)
|
H00059 | Huntington's disease (HD) |
P42858
(related)
|
H00094 | DNA repair defects |
P54132
(related)
|
H00296 | Defects in RecQ helicases |
P54132
(related)
|
H01296 | Hereditary neuropathy with liability to pressure palsies (HNPP) |
Q01453
(related)
|
H00001 | Acute lymphoblastic leukemia (ALL) (precursor B lymphoblastic leukemia) |
Q03164
(related)
Q03164 (marker) |
H00002 | Acute lymphoblastic leukemia (ALL) (precursor T lymphoblastic leukemia) |
Q03164
(related)
|
H00720 | Long QT syndrome |
Q12809
(related)
|
H00725 | Short QT syndrome |
Q12809
(related)
|
H00455 | Spinal muscular atrophy (SMA) |
Q16637
(related)
|
H00063 | Spinocerebellar ataxia (SCA) |
Q99700
(related)
|
H00403 | Disorders of nucleotide excision repair |
Q9Y253
(related)
|