KEGG ORTHOLOGY: K12304

ORTHOLOGY: K12304

Entry

K12304                      KO

Symbol

CANT1

Name

soluble calcium-activated nucleotidase 1 [EC:3.6.1.6]

Pathway

map00230

Purine metabolism

map00240

Pyrimidine metabolism

map01100

Metabolic pathways

map01232

Nucleotide metabolism

Reaction

R00155

UDP phosphohydrolase

R00328

GDP phosphohydrolase

R00961

IDP phosphohydrolase

Disease

H00476

Multiple epiphyseal dysplasia

H00494

Desbuquois syndrome

Brite

KEGG Orthology (KO) [BR:ko00001]
09100 Metabolism
  09104 Nucleotide metabolism
   00230 Purine metabolism
    K12304  CANT1; soluble calcium-activated nucleotidase 1
   00240 Pyrimidine metabolism
    K12304  CANT1; soluble calcium-activated nucleotidase 1
Enzymes [BR:ko01000]
3. Hydrolases
  3.6  Acting on acid anhydrides
   3.6.1  In phosphorus-containing anhydrides
    3.6.1.6  nucleoside diphosphate phosphatase
     K12304  CANT1; soluble calcium-activated nucleotidase 1

Other DBs

GO:

0017110

Genes

HSA:	124583(CANT1)

PTR:	468345(CANT1)

PPS:	100974659(CANT1)

GGO:	115934947(CANT1)

PON:	100454763(CANT1)

NLE:	100601352(CANT1)

HMH:	116483942(CANT1)

MCC:	710935(CANT1)

MCF:	102127579(CANT1)

MTHB:

126939220

MNI:	105469252(CANT1)

CSAB:

103243671(CANT1)

CATY:

105577637(CANT1)

PANU:

101011745(CANT1)

TGE:	112609605(CANT1)

MLEU:

105546706(CANT1)

RRO:	104677031(CANT1)

RBB:	108534172(CANT1)

TFN:	117066783(CANT1)

PTEH:

111534949(CANT1)

CANG:

105522117(CANT1)

CJC:	100402589(CANT1)

SBQ:	101044293(CANT1)

CIMI:

108301734(CANT1)

CSYR:

103249698(CANT1)

MMUR:

105866699(CANT1)

LCAT:

123621214(CANT1)

OGA:	100959410(CANT1)

MMU:	76025(Cant1)

MCAL:

110305208(Cant1)

MPAH:

110331475(Cant1)

RNO:	246272(Cant1)

MCOC:

116078228(Cant1)

ANU:	117711221(Cant1)

MUN:	110550202(Cant1)

CGE:	100767250(Cant1)

MAUA:

101825732(Cant1)

PROB:

127219741(Cant1)

PLEU:

114708956(Cant1)

MORG:

121436207(Cant1)

MFOT:

126500432

AAMP:

119812504(Cant1)

NGI:	103747295(Cant1)

HGL:	101708374(Cant1)

CPOC:

100725891(Cant1)

CCAN:

109682707(Cant1)

DORD:

105980115(Cant1)

DSP:	122096592(Cant1)

PLOP:

125365405(Cant1)

NCAR:

124981011

OPI:	101520524(CANT1)

TUP:	102482611(CANT1)

GVR:	103593213(CANT1)

AML:	109488325(CANT1)

ELK:

111160259

MPUF:

106003413(CANT1)

NVS:	122905925(CANT1)

EJU:	114216321(CANT1)

PVIV:

125152016(CANT1)

PTG:	102968784(CANT1)

PPAD:

109276834(CANT1)

HHV:	120228156(CANT1)

BTA:	518086(CANT1)

BOM:	102272160(CANT1)

BIU:	109574131(CANT1)

BBUB:

102401428(CANT1)

BBIS:

105000405(CANT1)

CHX:	102177094(CANT1)

OAS:	101122609(CANT1)

BTAX:

128064655(CANT1)

ODA:	120866816(CANT1)

CCAD:

122437863(CANT1)

MBEZ:

129544651(CANT1)

SSC:	100620107(CANT1)

CFR:	102507072(CANT1)

CBAI:

105065590(CANT1)

CDK:	105105800(CANT1)

VPC:	102545255(CANT1)

BACU:

103016453(CANT1)

BMUS:

118887257(CANT1)

LVE:	103069753(CANT1)

DLE:	111182745(CANT1)

PCAD:

102989446(CANT1)

PSIU:

116745867(CANT1)

NASI:

112410367(CANT1)

ECB:	100057405(CANT1)

EPZ:	103551442(CANT1)

EAI:	106845398(CANT1)

MYB:	102251396(CANT1)

MYD:	102768384(CANT1)

MMYO:

118671990(CANT1)

PKL:	118704521(CANT1)

EFUS:

103298245(CANT1)

MNA:	107532051(CANT1)

DRO:	112298696(CANT1)

SHON:

118999559(CANT1)

AJM:	119058625(CANT1)

PDIC:

114504004(CANT1) 114504111

PHAS:

123816742(CANT1)

MMF:	118634515(CANT1)

PPAM:

129086491(CANT1)

HAI:	109383715(CANT1)

PALE:

102886824(CANT1)

PGIG:

120600315(CANT1)

RAY:	107510071(CANT1)

TOD:	119232277(CANT1)

SARA:

101556034(CANT1)

SETR:

126013494(CANT1)

LAV:	100670458(CANT1)

TMU:

101346902

ETF:	101652217(CANT1)

DNM:	101447553(CANT1)

MDO:	100026552(CANT1)

GAS:	123244128(CANT1)

SHR:	100934101(CANT1)

AFZ:

127560685

PCW:	110193938(CANT1)

OAA:	100088014(CANT1)

GGA:	430103(CANT1)

PCOC:

116232535(CANT1)

MGP:	100546671(CANT1)

CJO:	107322204(CANT1)

TPAI:

128082907(CANT1)

LMUT:

125702261(CANT1)

NMEL:

110407357(CANT1)

APLA:

119713199(CANT1)

ACYG:

106046784(CANT1)

CATA:

118259293(CANT1)

AFUL:

116496521(CANT1)

TGU:	100219260(CANT1)

LSR:	110472436(CANT1)

SCAN:

103819741(CANT1)

PMOA:

120505513(CANT1)

OTC:	121338236(CANT1)

PRUF:

121363444(CANT1)

GFR:	102035478(CANT1)

FAB:	101811604(CANT1)

OMA:	130260357(CANT1)

PHI:	102108288(CANT1)

PMAJ:

107212434(CANT1)

CCAE:

111937476(CANT1)

CCW:	104698209(CANT1)

CBRC:

103613237(CANT1)

ETL:	114060374(CANT1)

ZAB:

106629946

ACHL:

103811143(CANT1)

SVG:	106859961(CANT1)

MMEA:

130582019(CANT1)

HRT:	120760967(CANT1)

FPG:	101912651(CANT1)

FCH:	102057968(CANT1)

CLV:	102084729(CANT1)

EGZ:	104133521(CANT1)

NNI:	104015047(CANT1)

PCRI:

104024933(CANT1)

PLET:

104620695(CANT1)

PCAO:

104049618(CANT1)

TALA:

104363503(CANT1)

PADL:

103917408(CANT1)

AFOR:

103896887(CANT1)

ACHC:

115341001(CANT1)

HALD:

104325989(CANT1)

HLE:	104832101(CANT1)

AGEN:

126043452

GCL:

127024047

CCRI:

104156151(CANT1)

CSTI:

104557862(CANT1)

CMAC:

104473532(CANT1)

BREG:

104632215(CANT1)

FGA:	104073609(CANT1)

GSTE:

104256218(CANT1)

LDI:	104347108(CANT1)

NNT:	104407241(CANT1)

SHAB:

115616560(CANT1)

DPUB:

104297876(CANT1)

PGUU:

104466985(CANT1)

ACAR:

104522830(CANT1)

CPEA:

104398512(CANT1)

AVIT:

104275528(CANT1)

CVF:	104290142(CANT1)

RTD:	128918124(CANT1)

CUCA:

104059435(CANT1)

TEO:	104370127(CANT1)

BRHI:

104502337(CANT1)

AAM:	106487146(CANT1)

AROW:

112974778(CANT1)

NPD:	112945326(CANT1)

DNE:	112991620(CANT1)

SCAM:

104150340(CANT1)

ASN:	102387737(CANT1)

AMJ:	102558883(CANT1)

CPOO:

109314889(CANT1)

GGN:	109296168(CANT1)

PSS:	102457946(CANT1)

CMY:	102947400(CANT1)

CCAY:

125621298(CANT1)

DCC:	119843242(CANT1)

CPIC:

101936718(CANT1)

TST:	117887638(CANT1)

CABI:

116835884(CANT1)

MRV:	120383780(CANT1)

ACS:	100563392(cant1)

ASAO:

132768453(CANT1)

PVT:	110090286(CANT1)

SUND:

121922789(CANT1)

PBI:	103051878(CANT1)

PMUR:

107292203(CANT1)

CTIG:

120308779(CANT1)

TSR:	106543734(CANT1)

PGUT:

117663014(CANT1)

APRI:

131193568(CANT1)

PTEX:

113437046(CANT1)

NSS:	113411970(CANT1)

VKO:	123018093(CANT1)

PMUA:

114589083(CANT1)

PRAF:

128407338(CANT1)

ZVI:	118079715(CANT1)

HCG:	128347662(CANT1)

GJA:	107115314(CANT1)

STOW:

125429636(CANT1)

EMC:	129329343(CANT1)

XLA:	379060(cant1.L)

XTR:	394537(cant1)

NPR:	108796391(CANT1)

RTEM:

120918883(CANT1)

BBUF:

121003821(CANT1)

BGAR:

122940305(CANT1)

MUO:	115473560 115473561

GSH:	117368712(CANT1)

DRE:	406558(cant1a) 445201(cant1b)

SRX:	107717471 107732154(cant1)

SANH:

107671255 107700370 107702024

SGH:	107552124 107564575 107567625 107571310

CCAR:

109045504 109047172 109097183 109109047

CAUA:

113047564 113053115 113055551 113055558 113111285

CGIB:

127934345 127944612 127953150 127967899 128021948

PTET:

122335182(cant1a) 122353942(cant1b)

LROH:

127162345(cant1a) 127173250(cant1b)

OMC:	131536326(cant1a) 131549399(cant1b)

PPRM:

120476221 120476222 120491972(cant1b)

RKG:	130076621(cant1b) 130095253(cant1a)

MAMB:

125243242(cant1a) 125256135(cant1b)

CIDE:

127508283 127522876

MASI:

127426499 127428122 127450371 127452166

TROS:

130560799(cant1a) 130571388(cant1b)

TDW:	130410137(cant1b)

MANU:

129427031(cant1a) 129427565(cant1b)

IPU:	108270889(cant1b)

IFU:	128613294(cant1b)

PHYP:

113536555(cant1)

SMEO:

124391247(cant1b)

TFD:	113653445(cant1b)

TVC:	132855861(cant1b)

TRN:	134331694(cant1b)

AMEX:

103034776 103035312

CMAO:

118818699(cant1b) 118821488(cant1a)

EEE:	113575230 113589693

CHAR:

122132080

TRU:	101063748 101076188

TFS:	130515398(cant1a) 130527973(cant1b)

TNG:	GSTEN00018574G001 GSTEN00026236G001

LCO:	104922273 104925070(cant1)

NCC:

104950180

TBEN:

117474669(cant1b) 117493529(cant1a)

CGOB:

115010325 115012382

PGEO:

117450826(cant1a) 117458211(cant1b)

GACU:

117548689(cant1a) 117561722(cant1b)

EMAC:

134864820(cant1b) 134877460(cant1a)

ELY:	117255351(cant1b) 117267787(cant1a)

EFO:	125879806(cant1a) 125885651(cant1b)

PLEP:

121941847(cant1b) 121956498(cant1a)

SLUC:

116042598(cant1b) 116059696(cant1a)

ECRA:

117936661(cant1b) 117958652(cant1a)

ESP:	116702564 116704974 116706978

PFLV:

114569538(cant1) 114570446

GAT:	120825244 120827966(cant1a)

PPUG:

119218259(cant1b) 119220836(cant1a)

AFB:	129096115(cant1b) 129098689(cant1a)

CLUM:

117735283(cant1a) 117737271 117737323

PSWI:

130189321(cant1a) 130190708(cant1b)

MSAM:

119890217(cant1a) 119899551(cant1b)

SCHU:

122868895(cant1a) 122873979(cant1b)

CUD:	121508371(cant1b) 121529488(cant1a)

ALAT:

119013931(cant1a) 119021648(cant1b)

MZE:	101466916(cant1) 101480607

ONL:	100701747(cant1) 102078803

OAU:	116325233(cant1a) 116330955(cant1b)

OLA:	101171168(cant1) 101172636

OML:	112137424(cant1b) 112146028(cant1a)

CSAI:

133421495(cant1a) 133444726(cant1b)

XMA:	102222865(cant1) 102226786

XCO:	114144359 114159986(cant1)

XHE:	116719745 116734887(cant1)

PRET:

103465407 103468847(cant1)

PFOR:

103140961(cant1) 103150496

PLAI:

106936696(cant1) 106951258

PMEI:

106917535 106920084(cant1)

GAF:	122821810(cant1a) 122829587(cant1b)

PPRL:

129363760(cant1a) 129366806(cant1b)

CVG:	107083186(cant1) 107090774

CTUL:

119778279(cant1a) 119783280(cant1b)

GMU:	124863431 124863998 124867953(cant1b)

NFU:	107377059 107392387

KMR:	108236422(cant1b) 108241365(cant1a)

ALIM:

106518670 106521437

NWH:	119421658(cant1a) 119422832

AOCE:

111564630 111579424 111581964

MCEP:

124997248 125003798(cant1b)

CSEM:

103392811(cant1)

POV:	109627738 109638727(cant1)

SSEN:

122760626 122771485(cant1b) 122785187(cant1a)

HHIP:

117765688(cant1a) 117766134(cant1b)

HSP:	118119853(cant1b) 118123085(cant1a)

PPLT:

128437058(cant1b) 128458025(cant1a)

SMAU:

118288722(cant1a) 118313148(cant1b)

LCF:	108875629 108902724(cant1a)

SDU:	111227038(cant1) 111229434

SLAL:

111657780(cant1) 111666685

XGL:	120784520(cant1a) 120800241(cant1b)

HCQ:	109517726(cant1) 109527423

SSCV:

125968614 125984006

SBIA:

133505561(cant1b) 133513969(cant1a)

PEE:	133403533(cant1b) 133414937(cant1a)

PTAO:

133465472(cant1a) 133476451(cant1b)

BPEC:

110165198 110168045 110168394

MALB:

109957848 109972252(cant1)

BSPL:

114860518(cant1a) 114865619(cant1b)

SJO:	128375509(cant1b) 128379085(cant1a)

SASA:

100195480(cant1) 106564354 106591143 106592000 106606400 106606402

STRU:

115147544 115171815 115184177 115207194

OTW:	112239798(cant1a) 112242090(cant1b) 121838604

OMY:	110485510 110485511 110487066 110487067

OGO:	124020825 124026058

ONE:

115128175

OKI:	109876849 109877380 109877398 116366565

OKE:	118371787(cant1a) 118381862(cant1b)

SNH:	120018138 120041437 120041641 120041691

CCLU:

121534283(cant1b) 121551214 121568711

ELS:	105012018 105013048(cant1)

SFM:	108922499 108930275

PKI:	111839609(cant1) 111846605

AANG:

118216839(cant1a) 118221485

LOC:	102689065(cant1)

PSPA:

121295646(cant1b) 121296255 121307574

ARUT:

117423361 117424519(cant1a)

PSEX:

120518201(cant1b)

LCM:	102345277(CANT1)

CMK:	103175547(cant1a)

RTP:

109931464

CPLA:

122562212(cant1b)

HOC:	132828002(cant1a)

LERI:

BFO:

BBEL:

CIN:

SCLV:

SPU:

LPIC:

APLC:

AJC:

SKO:

DME:	Dmel_CG5276(CG5276)

DER:

6553859

DSE:

6606824

DSI:	Dsimw501_GD18755(Dsim_GD18755)

DYA:	Dyak_GE26097

DAN:

DSR:

DPO:

DPE:

DMN:

DWI:

DGR:

DMO:	Dmoj_GI10286

DAZ:

108609199

DNV:

108659708

DHE:	111604562 115482801

DVI:

CCAT:

BOD:

BDR:

RZE:	108355026 108372677 108377396

AOQ:

129247262

TDA:

119676176

MDE:	101895011 131806934

SCAC:

LCQ:

LSQ:

GFS:

ECOE:

CLON:

HIS:

AGA:

ACOZ:

AARA:

AMER:

ASTE:

AFUN:

AMOU:

AALI:

AAG:	110677770 5568212

AALB:

109422742

CQU:	CpipJ_CPIJ006723

CPII:

CNS:

BCOO:

AME:

ACER:

ALAB:

ADR:

AFLR:

BIM:

BBIF:

BVK:

BVAN:

BTER:

BAFF:

BPYO:

BPAS:

FVI:

CCAL:

OBB:

OLG:

MGEN:

NMEA:

CGIG:

SOC:

MPHA:

AEC:

ACEP:

PBAR:

VEM:

HST:

DQU:

CFO:

FEX:

LHU:

PGC:

OBO:

PCF:

PFUC:

VPS:

VCRB:

VVE:

NVI:

CSOL:

TPRE:

LHT:

LBD:

MDL:

CGLO:

FAS:

DAM:

AGIF:

CINS:

VCAN:

CCIN:

DSM:

NPT:

NFB:

NLO:

NVG:

AROA:

TCA:

DPA:

SOY:

AGRG:

ATD:

CSET:

AGB:

LDC:

DVV:

NVL:

APLN:

PPYR:

116171313 116178387 116179673

OTU:

BMOR:

BMAN:

MSEX:

DPL:	KGM_205738

BANY:

MJU:

NIQ:

VCD:

MCIX:

PMAC:

PPOT:

PXU:

PRAP:

PBX:

PNAP:

ZCE:

CCRC:

LSIN:

AAGE:

HAW:

HZE:

TNL:

SLIU:

OFU:

PXY:

PGW:

CFEL:

CCRN:

API:	100166504 103308894

DNX:	107170676 107171755

AGS:	114125927 114131092 114131093

RMD:	113556652 113561078

ACOO:

126835372 126835676 126841547 126845078 126845780

DVT:	126894326 126904088 126904093 126910485

BTAB:

109037793

DCI:	103509559 103516223 103516319 103522838

CLEC:

106669807 106669828

HHAL:

106688646

NLU:

111064320

HVI:	124353918 124362206 124362208

MQU:	128999733 129001537

PHU:	Phum_PHUM421050

FOC:

TPAL:

ZNE:

CSEC:

SGRE:

BROR:

IEL:

FCD:	110849692 110853370

DPX:	DAPPUDRAFT_188560

DMK:

DPZ:

PVM:

PJA:

PCHN:

PMOO:

HAME:

PCLA:

CQD:

PTRU:

ESN:

MNZ:

HAZT:

EAF:

LSM:	121122824 121122825 121126596

TCF:

PPOI:

DSV:

RSAN:

RMP:

VDE:

VJA:

DPTE:

113794534 113796790 113797960

DFR:

CSCU:

PTEP:

ABRU:

UDV:

SDM:

LPOL:

PMEO:

CEL:	CELE_F08C6.6(apy-1) CELE_ZK563.7(ZK563.7)

CBR:	CBG_14198 CBG_16731

CRQ:	GCK72_024085 GCK72_024807

NAI:	NECAME_04539 NECAME_04976 NECAME_04977 NECAME_05333 NECAME_05334 NECAME_18038 NECAME_18602

BMY:	BM_BM3194(Bma-apy-1)

LOA:	LOAG_01305

TSP:

Tsp_09215

HRO:	HELRODRAFT_69675 HELRODRAFT_77501

PCAN:

112556813

BGT:

106057153

GAE:	121366368 121378913

HRF:

HRJ:

CRG:

CVN:

CANU:

OED:

MYI:

PMAX:

MCAF:

MMER:

RPHI:

DPOL:

OBI:

OSN:

LAK:

NVE:

EPA:

ATEN:

ADF:

AMIL:

PDAM:

SPIS:

DGT:

XEN:

HMG:

HSY:

TAD:	TRIADDRAFT_21256

AQU:

100640578

CME:	CYME_CMQ456C

GSL:	Gasu_48820

CCP:	CHC_T00003677001

MBR:	MONBRDRAFT_28836

SRE:	PTSG_08624

EHI:	EHI_053610(59.t00033) EHI_103690(348.t00005) EHI_104590(415.t00008) EHI_112890(17.t00006)

EDI:	EDI_058390 EDI_125320 EDI_305410 EDI_330850

EIV:	EIN_023510 EIN_097870 EIN_313030 EIN_419280

ACAN:

ACA1_277780 ACA1_330420 ACA1_330550

CPV:

cgd6_1570

CHO:	Chro.60194

TGO:	TGME49_310810

SMIN:

v1.2.014804.t1(symbB.v1.2.014804.t1) v1.2.033374.t1(symbB.v1.2.033374.t1)

PTI:	PHATRDRAFT_14301

FCY:	FRACYDRAFT_177693

TPS:	THAPSDRAFT_31247

AAF:	AURANDRAFT_31875

PIF:	PITG_20792

PSOJ:

PHYSODRAFT_354969

SPAR:

SPRG_05815 SPRG_15841

NGR:	NAEGRDRAFT_70056 NAEGRDRAFT_79292

PSTT:

CH92_09400

PZD:	KQ248_14365

IDT:	C5610_00330

HMI:	soil367_13810

ABAW:

D5400_09450

» show all

Reference

PMID:12167635

Authors

Failer BU, Braun N, Zimmermann H

Title

Cloning, expression, and functional characterization of a Ca(2+)-dependent endoplasmic reticulum nucleoside diphosphatase.

Journal

J Biol Chem 277:36978-86 (2002)
DOI:10.1074/jbc.M201656200

Sequence

[hsa:124583] [rno:246272]

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