KEGG ORTHOLOGY: K14019

ORTHOLOGY: K14019

Entry

K14019                      KO

Symbol

PPP1R15A, GADD34

Name

protein phosphatase 1 regulatory subunit 15A

Pathway

map04141

Protein processing in endoplasmic reticulum

Brite

KEGG Orthology (KO) [BR:ko00001]
09120 Genetic Information Processing
  09123 Folding, sorting and degradation
   04141 Protein processing in endoplasmic reticulum
    K14019  PPP1R15A, GADD34; protein phosphatase 1 regulatory subunit 15A
09180 Brite Hierarchies
  09181 Protein families: metabolism
   01009 Protein phosphatases and associated proteins
    K14019  PPP1R15A, GADD34; protein phosphatase 1 regulatory subunit 15A
Protein phosphatases and associated proteins [BR:ko01009]
Protein serine/threonine phosphatases
  Phosphoprotein phosphatases (PPPs)
   Protein phosphatase-1
    PP1-interacting proteins (PIPs)
     K14019  PPP1R15A, GADD34; protein phosphatase 1 regulatory subunit 15A

Genes

HSA:	23645(PPP1R15A)

PTR:	456191(PPP1R15A)

PPS:	100993910(PPP1R15A)

GGO:	101151443(PPP1R15A)

PON:	100449481(PPP1R15A)

NLE:	100591446(PPP1R15A)

HMH:	116478229(PPP1R15A)

MCC:	718350(PPP1R15A)

MCF:	102128912(PPP1R15A)

MTHB:

126943555

MNI:	105478661(PPP1R15A)

CATY:

105595261(PPP1R15A)

TGE:	112612218(PPP1R15A)

MLEU:

105539170(PPP1R15A)

RRO:	104666545(PPP1R15A)

RBB:	108523638(PPP1R15A)

TFN:	117091531(PPP1R15A)

PTEH:

111520035(PPP1R15A)

CANG:

105514792(PPP1R15A)

CJC:	100405468(PPP1R15A)

SBQ:	101048709(PPP1R15A)

CIMI:

108283904(PPP1R15A)

CSYR:

103249903(PPP1R15A)

MMUR:

105865590(PPP1R15A)

LCAT:

123623849(PPP1R15A)

PCOQ:

105809435(PPP1R15A)

OGA:	100947110(PPP1R15A)

MMU:	17872(Ppp1r15a)

MCAL:

110298662(Ppp1r15a)

MPAH:

110331947(Ppp1r15a)

RNO:	171071(Ppp1r15a)

MCOC:

116102205(Ppp1r15a)

ANU:	117719653(Ppp1r15a)

MUN:	110540626(Ppp1r15a)

CGE:	100757625(Ppp1r15a)

MAUA:

101824834(Ppp1r15a)

PROB:

127213887(Ppp1r15a)

PLEU:

114684702(Ppp1r15a)

MORG:

121432741(Ppp1r15a)

MFOT:

126488209

AAMP:

119802746(Ppp1r15a)

NGI:	103743635(Ppp1r15a)

HGL:	101715557(Ppp1r15a)

CPOC:

100727559(Ppp1r15a)

CCAN:

109682680(Ppp1r15a)

DORD:

105994122(Ppp1r15a)

DSP:	122125795(Ppp1r15a)

PLOP:

125338851(Ppp1r15a)

NCAR:

124966835

MMMA:

107151271(Ppp1r15a)

OCU:

100357623

OPI:	101532419(PPP1R15A)

TUP:	102472204(PPP1R15A)

GVR:	103587758(PPP1R15A)

CFA:	476419(PPP1R15A)

CLUD:

112645183(PPP1R15A)

VVP:	112931341(PPP1R15A)

VLG:	121485602(PPP1R15A)

NPO:	129500941(PPP1R15A)

AML:	100471595(PPP1R15A)

UMR:	103657105(PPP1R15A)

UAH:	113243327(PPP1R15A)

UAR:	123776325(PPP1R15A)

ELK:

111160734

LLV:

125089778

MPUF:

101689560(PPP1R15A)

MNP:	132004941(PPP1R15A)

MLK:	131817767(PPP1R15A)

NVS:	122911848(PPP1R15A)

ORO:	101382397(PPP1R15A)

EJU:	114199637(PPP1R15A)

ZCA:	113936268(PPP1R15A)

MLX:	117998240(PPP1R15A)

NSU:	110572850(PPP1R15A)

LWW:	102726352(PPP1R15A)

FCA:	101084589(PPP1R15A)

PCOO:

112851102(PPP1R15A)

PBG:	122494854(PPP1R15A)

PVIV:

125153653(PPP1R15A)

LRUF:

124510933

PTG:	102970949(PPP1R15A)

PPAD:

109253102(PPP1R15A)

PUC:

125916041

AJU:

106988706

HHV:	120243330(PPP1R15A)

BTA:	514688(PPP1R15A)

BOM:	102264575(PPP1R15A)

BIU:	109572694(PPP1R15A)

BBUB:

102398332(PPP1R15A)

BBIS:

104995628(PPP1R15A)

CHX:	102186898(PPP1R15A)

OAS:	101102415(PPP1R15A)

BTAX:

128062881(PPP1R15A)

ODA:	120872163(PPP1R15A)

CCAD:

122420322(PPP1R15A)

MBEZ:

129546568(PPP1R15A)

SSC:	100522679(PPP1R15A)

CFR:	102520860(PPP1R15A)

CBAI:

105062608(PPP1R15A)

CDK:	105102894(PPP1R15A)

VPC:	102529678(PPP1R15A)

BACU:

103017208(PPP1R15A)

BMUS:

118885904(PPP1R15A)

LVE:	103083071(PPP1R15A)

OOR:	101289075(PPP1R15A)

DLE:	111180643(PPP1R15A)

PCAD:

102975469(PPP1R15A)

PSIU:

116743571(PPP1R15A)

NASI:

112415254(PPP1R15A)

ECB:	100051382(PPP1R15A)

EPZ:	103553315(PPP1R15A)

EAI:	106838262(PPP1R15A)

MYB:	102258962(PPP1R15A)

MYD:	102760852(PPP1R15A)

MMYO:

118654978 118655393(PPP1R15A) 118656533

MLF:	102425426(PPP1R15A)

PKL:	118712161(PPP1R15A)

EFUS:

103297650(PPP1R15A)

MNA:	107531903(PPP1R15A)

DRO:	112310205(PPP1R15A)

AJM:	119039748(PPP1R15A)

PDIC:

114511649(PPP1R15A)

PHAS:

123830343(PPP1R15A)

MMF:	118639353(PPP1R15A)

PPAM:

129082913(PPP1R15A)

HAI:	109390970(PPP1R15A)

RFQ:	117035120(PPP1R15A)

PALE:

102885218(PPP1R15A)

PGIG:

120606962(PPP1R15A)

RAY:	107498869(PPP1R15A)

MJV:	108400336(PPP1R15A)

TOD:	119249539(PPP1R15A)

SARA:

101537337(PPP1R15A)

SETR:

126027192(PPP1R15A)

LAV:	100660843(PPP1R15A)

TMU:

101355712

DNM:	101433630(PPP1R15A)

GAS:	123254995(PPP1R15A)

SHR:	105750111(PPP1R15A)

PCW:	110219695(PPP1R15A)

OAA:	100087159(PPP1R15A)

ASN:	102376825(PPP1R15A)

AMJ:	102574155(PPP1R15A)

CPIC:

101949125(PPP1R15A)

ACS:	103280318(ppp1r15a)

PVT:	110078485(PPP1R15A)

PBI:	103062898(PPP1R15A)

PMUR:

107282487(PPP1R15A)

TSR:

106550127

PMUA:

114581587(PPP1R15A)

ZVI:	118094791(PPP1R15A)

GJA:	107116615(PPP1R15A)

SMEO:

124380755

TFD:	113657487(ppp1r15a)

TPAL:

PCHN:

PCLA:

PTRU:

Reference

PMID:19131336

Authors

Lee YY, Cevallos RC, Jan E

Title

An upstream open reading frame regulates translation of GADD34 during cellular stresses that induce eIF2alpha phosphorylation.

Journal

J Biol Chem 284:6661-73 (2009)
DOI:10.1074/jbc.M806735200

Sequence

[hsa:23645] [mmu:17872] [rno:171071]

Reference

PMID:14718519

Authors

Shi W, Sun C, He B, Xiong W, Shi X, Yao D, Cao X

Title

GADD34-PP1c recruited by Smad7 dephosphorylates TGFbeta type I receptor.

Journal

J Cell Biol 164:291-300 (2004)
DOI:10.1083/jcb.200307151

Sequence

[hsa:23645]

All links

Ontology (2)   
   KEGG BRITE (2)   
Pathway (2)   
   KEGG PATHWAY (2)   
Gene (176)   
   KEGG GENES (160)   
   KEGG MGENES (6)   
   RefGene (8)   
   OC (2)   
Literature (2)   
   PubMed (2)   
All databases (182)   

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