KEGG ORTHOLOGY: K14423

ORTHOLOGY: K14423

Entry

K14423                      KO

Symbol

SMO1

Name

plant 4,4-dimethylsterol C-4alpha-methyl-monooxygenase [EC:1.14.18.10]

Pathway

map00100

Steroid biosynthesis

map01100

Metabolic pathways

map01110

Biosynthesis of secondary metabolites

Module

M00917

Phytosterol biosynthesis, squalene 2,3-epoxide => campesterol/sitosterol

Reaction

R12377

24-methylidenecycloartanol,ferrocytochrome-b5:oxygen oxidoreductase (C-4alpha-methyl-hydroxylating)

Brite

KEGG Orthology (KO) [BR:ko00001]
09100 Metabolism
  09103 Lipid metabolism
   00100 Steroid biosynthesis
    K14423  SMO1; plant 4,4-dimethylsterol C-4alpha-methyl-monooxygenase
Enzymes [BR:ko01000]
1. Oxidoreductases
  1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen
   1.14.18  With another compound as one donor, and incorporation of one atom of oxygen into the other donor
    1.14.18.10  plant 4,4-dimethylsterol C-4alpha-methyl-monooxygenase
     K14423  SMO1; plant 4,4-dimethylsterol C-4alpha-methyl-monooxygenase

Genes

ATH:	AT4G12110(SMO1-1) AT4G22755 AT4G22756(SMO1-2)

ALY:	110226378 110226382 9310821

CRB:	111829641 111829642 17878277 17884650

CSAT:

104707512 104717801 104718035 104718036 104720179 104722765 104722766 104722767 104731224 104731225 104733374 104737226

EUS:	EUTSA_v10024722mg EUTSA_v10025849mg EUTSA_v10028846mg

BRP:	103853483 103860261 103860313

BNA:	106375731 106375734 106376550 106395025 106440893 106440900

BOE:	106323132 106323529 106326927

RSZ:	108819044 108822182 108826950

THJ:	104813000 104813925

CPAP:

110817604 110819441

CIT:

102610279

CIC:	CICLE_v10021364mg

PVY:	116125412 116128115 116128172

MINC:

123204022 123210056

TCC:	18606367 18614230 18614300 18614301 18614438

GRA:	105763824 105763825 105765153 105792123 105800261

GHI:	107890661 107896508 107919482 107919503 107926922 107931276 107936415 107945640 107945641 107946958

GAB:	108457103 108458635 108458637 108468960 108479411

HSYR:

120192020 120202626 120206712 120213721

DZI:	111289871 111305927 111306357 111315419

EGR:	104441851 104443730

GMX:	100785755 100793153 100793785

GSJ:	114367510 114393840 114396051 114412109

PVU:	PHAVU_008G076300g PHAVU_010G081300g

VRA:	106769322 106779599

VAR:	108324101 108328655

VUN:	114179939 114185995

VUM:	124828945 124846174

CCAJ:

109802330 109809965

APRC:

113850460 113852978

MTR:	11426366 25498869

TPRA:

123887250

CAM:	101498049 101499136

PSAT:

127074119 127127223 127130959

VVO:	131614309 131637420 131637564

LJA:	Lj4g3v1302690.1(Lj4g3v1302690.1)

ADU:	107471219 107487621

AIP:	107623619 107630595

AHF:	112716478 112721686 112783349 112803654

LANG:

109333400 109350013

PCIN:

129288105 129311756 129321842

QSA:	O6P43_024284 O6P43_034150

FVE:	105351403 105352873

RCN:	112177775 112180715

PPER:

18778059 18785578

PMUM:

103331830 103337274 107881149

PAVI:

110753700 110773748

PDUL:

117618692 117629198

MDM:	103420445 103433067

MSYL:

126620118 126628621

PXB:	103930498 103938116 103958174 103962383

ZJU:	107430251 107435696

MNT:

CSAV:

CSV:

CMO:

BHJ:

MCHA:

CMAX:

CMOS:

CPEP:

RCU:	107262576 8288054

JCU:	105643118 105645947

HBR:	110631783 110645323 110647686 110658049

MESC:

110600473 110607085

POP:	18094413 7479230 7488901

PEU:	105128938 105132225 105132487

PALZ:

118028552 118036059 118041303

JRE:	108981850 109011030 118347633

CILL:

CAVE:

QSU:

QLO:

TWL:	119980425 120016721

VVI:

100255536

VRI:

117905901

SLY:	101262546 104649012

SPEN:

107003251 107026679

SOT:	102605717 102606141

SSTN:

125845263 125878424

SDUL:

129886681 129889921

CANN:

107866563 107873120

LBB:	132635036 132645703

NTA:	107798822 107809242 107810865 107828110

NSY:	104225605 104227542

NTO:	104085939 104115593

NAU:	109211816 109214418

INI:	109147072 109149049 109165996

ITR:	116015051 116029935 116030447

SIND:

105155669 105164199 105173233

OEU:	111366033 111386563 111391303 111398487

EGT:

105965684

SSPL:

121744924 121791764 121796398 121800156 121811001

SMIL:

131025862

SHIS:

125186824 125194210

APAN:

127240281 127252576 127255379

HAN:	110864319 110864321 110864322 110867780

ECAD:

122585370 122611201

LSV:

111918756

CCAV:

112521181 112526832 112527858

DCR:	108206019 108211255

CSIN:

114262038 114299562 114311978

RVL:	131309923 131333476

AEW:	130752757 130782611 130793079

BVG:	104892421 104892422

SOE:	110779099 110784397

CQI:	110684683 110702588 110719378 110729310 110729358

ATRI:

130804405

MOF:

131163729

NNU:	104611228 104611828

MING:

122077742 122085506

TSS:	122648006 122669732

PSOM:

113275150 113304814 113306673

OSA:	4331338 4349278

DOSA:

Os03t0108500-01(Os03g0108500) Os10t0545200-01(Os10g0545200)

OBR:

102723086

OGL:	127753258 127768592

BDI:	100830254 100830279 100832018 100832062

ATS:	109735447 109742913 109743100 109752552 109759404

TDC:	119274638 119286504 119294101 119295277 119298075 119298399 119306308 119328285 119338387

TAES:

123051467 123085710 123086677 123089447 123091300 123096278 123100508 123105854 123107910 123125632 123127385 123161960 123162077 123181575

TUA:	125506347 125510783 125512642 125525429 125550745

LPER:

127294147 127297591 127308143

LRD:	124648424 124671406 124676848 124694335 124699427 124699687 124708784 124708790

SBI:	8062847 8069599 8071163 8077962

ZMA:	100217119 100282314

SITA:

101762442 101770857

SVS:	117840008 117859214

PVIR:

120647612 120651800 120673669 120686746 120688009 120691786 120693297 120707052

PHAI:

112873879 112877714 112882554 112894791 112898047 112902836

PDA:	103714140 103718600 103720910

EGU:	105033591 105035357 105042945

MUS:	103972099 103972632 103985734 103985805 103995011

ZOF:	121971199 121976464 121980898 121981501 121982993 121984786 121985379 122025017

DCT:

110101909

PEQ:

110036326

AOF:	109837083 109838522

MSIN:

131248396

NCOL:

116247288 116262006 116262605 116262607

ATR:

18441549

SMO:	SELMODRAFT_104109 SELMODRAFT_170047

PPP:	112279680 112281769

» show all

Reference

PMID:14653780

Authors

Darnet S, Rahier A

Title

Plant sterol biosynthesis: identification of two distinct families of sterol 4alpha-methyl oxidases.

Journal

Biochem J 378:889-98 (2004)
DOI:10.1042/BJ20031572

Sequence

[ath:AT4G12110 AT4G22756]

Reference

PMID:21147141

Authors

Rahier A

Title

Dissecting the sterol C-4 demethylation process in higher plants. From structures and genes to catalytic mechanism.

Journal

Steroids 76:340-52 (2011)
DOI:10.1016/j.steroids.2010.11.011

All links

Ontology (2)   
   KEGG BRITE (2)   
Pathway (7)   
   KEGG PATHWAY (6)   
   KEGG MODULE (1)   
Chemical reaction (3)   
   KEGG ENZYME (1)   
   KEGG REACTION (1)   
   KEGG RCLASS (1)   
Gene (602)   
   KEGG GENES (403)   
   KEGG MGENES (43)   
   RefGene (152)   
   OC (4)   
Literature (2)   
   PubMed (2)   
All databases (616)   

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