KEGG ORTHOLOGY: K16808

ORTHOLOGY: K16808

Entry

K16808                      KO

Symbol

NUMA1

Name

nuclear mitotic apparatus protein 1

Disease

H02542

Acute promyelocytic leukemia

Brite

KEGG Orthology (KO) [BR:ko00001]
09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03036 Chromosome and associated proteins
    K16808  NUMA1; nuclear mitotic apparatus protein 1
Chromosome and associated proteins [BR:ko03036]
Eukaryotic type
  Centrosome formation proteins
   Spindle formation proteins
    K16808  NUMA1; nuclear mitotic apparatus protein 1

Genes

HSA:	4926(NUMA1)

PTR:	451398(NUMA1)

PPS:	100995744(NUMA1)

GGO:	101145498(NUMA1)

PON:	100439501(NUMA1)

NLE:	100597582(NUMA1)

HMH:	116476627(NUMA1)

MCC:	718231(NUMA1)

MCF:	102138526(NUMA1)

MTHB:

126935011

MNI:	105468693(NUMA1)

CSAB:

103247986(NUMA1)

CATY:

105578907(NUMA1)

PANU:

100997993(NUMA1) 116272853

TGE:	112606435(NUMA1)

MLEU:

105549241(NUMA1)

RRO:	104665157(NUMA1)

RBB:	108543735(NUMA1)

TFN:	117081477(NUMA1)

PTEH:

111540898(NUMA1)

CANG:

105522305(NUMA1)

CJC:	100412992(NUMA1)

SBQ:	101052097(NUMA1)

CIMI:

108307514(NUMA1)

CSYR:

103268501(NUMA1)

MMUR:

105860323(NUMA1)

LCAT:

123641085(NUMA1)

PCOQ:

105811487(NUMA1)

OGA:	100945291(NUMA1)

MMU:	101706(Numa1)

MCAL:

110297463(Numa1)

MPAH:

110313178(Numa1)

RNO:	308870(Numa1)

MCOC:

116102677(Numa1)

ANU:	117698380(Numa1)

MUN:	110557559(Numa1)

CGE:	100762458(Numa1)

MAUA:

101844561(Numa1)

PROB:

127228001(Numa1)

PLEU:

114706628(Numa1)

MORG:

121463620(Numa1)

MFOT:

126488827

AAMP:

119810025(Numa1)

NGI:	103750815(Numa1)

HGL:	101700873(Numa1)

CPOC:

100714541(Numa1)

CCAN:

109684518(Numa1)

DORD:

105983929(Numa1)

DSP:	122114263(Numa1)

PLOP:

125361188(Numa1)

NCAR:

124958181

MMMA:

107135559(Numa1)

OCU:	100302677(NUMA1)

OPI:	101532393(NUMA1)

TUP:	102497033(NUMA1)

GVR:	103585880(NUMA1)

CFA:	485213(NUMA1)

CLUD:

112667465(NUMA1)

VVP:	112928696(NUMA1)

VLG:	121476283(NUMA1)

NPO:	129506679(NUMA1)

AML:	100476259(NUMA1)

UMR:	103678015(NUMA1)

UAH:	113269257(NUMA1)

UAR:	123782538(NUMA1)

ELK:

111159647

LLV:

125078300

MPUF:

101688910(NUMA1)

MNP:	132023724(NUMA1)

MLK:	131807918(NUMA1)

NVS:	122912622(NUMA1)

ORO:	101363362(NUMA1)

EJU:	114218690(NUMA1)

ZCA:	113915111(NUMA1)

MLX:	118003893(NUMA1)

NSU:	110593353(NUMA1)

LWW:	102733119(NUMA1)

FCA:	101096349(NUMA1)

PYU:	121039217(NUMA1)

PCOO:

112865736(NUMA1)

PBG:	122483386(NUMA1)

PVIV:

125177078(NUMA1)

LRUF:

124505321

PTG:	102973013(NUMA1)

PPAD:

109267123(NUMA1)

PUC:

125937027

AJU:

106966092

HHV:	120245118(NUMA1)

BTA:	513091(NUMA1)

BOM:	102274997(NUMA1)

BIU:	109569217(NUMA1)

BBUB:

102394918(NUMA1)

BBIS:

104995563(NUMA1)

CHX:	102171630(NUMA1)

OAS:	101119246(NUMA1)

BTAX:

128060842(NUMA1)

ODA:	120876716(NUMA1)

CCAD:

122449546(NUMA1)

MBEZ:

129554622(NUMA1)

SSC:	100526064(NUMA1)

CFR:	102517941(NUMA1)

CBAI:

105083279(NUMA1)

CDK:	105096640(NUMA1)

VPC:	102539975(NUMA1)

BACU:

103020294(NUMA1)

BMUS:

118898769(NUMA1)

LVE:	103087391(NUMA1)

OOR:	101272384(NUMA1)

DLE:	111170563(NUMA1)

PCAD:

102995505(NUMA1)

PSIU:

116757463(NUMA1)

NASI:

112390743(NUMA1)

ECB:	100052884(NUMA1)

EPZ:	103549347(NUMA1)

EAI:	106831648(NUMA1)

MYB:	102256998(NUMA1)

MYD:	102751498(NUMA1)

MMYO:

118664703(NUMA1)

MLF:	102417938(NUMA1)

PKL:	118713429(NUMA1)

EFUS:

103293659(NUMA1)

MNA:	107541146(NUMA1)

DRO:	112316096(NUMA1)

SHON:

119002654(NUMA1)

AJM:	119042097(NUMA1)

PDIC:

114498492(NUMA1)

PHAS:

123805644(NUMA1)

MMF:	118627668(NUMA1)

PPAM:

129072714(NUMA1)

HAI:	109372418(NUMA1)

RFQ:	117030232(NUMA1)

PALE:

102891874(NUMA1)

PGIG:

120590290(NUMA1)

PVP:	105303662(NUMA1)

RAY:	107517360(NUMA1)

MJV:	108405086(NUMA1)

TOD:	119255587(NUMA1)

SARA:

101542976(NUMA1)

SETR:

126018125(NUMA1)

LAV:	100666019(NUMA1)

TMU:

101351082

ETF:	101640600(NUMA1)

DNM:	101413777(NUMA1)

MDO:	100015927(NUMA1)

GAS:	123240486(NUMA1)

SHR:	100930865(NUMA1)

AFZ:

127555254

PCW:	110195204(NUMA1)

OAA:	100088311(NUMA1)

GGA:	768717(NUMA1)

PCOC:

116233911(NUMA1)

MGP:	100542302(NUMA1)

CJO:	107308516(NUMA1)

TPAI:

128074965(NUMA1)

LMUT:

125696125(NUMA1)

NMEL:

110391606(NUMA1)

APLA:

119716806(NUMA1)

ACYG:

106029429(NUMA1)

CATA:

118259752(NUMA1)

AFUL:

116500912(NUMA1)

TGU:	100226780(NUMA1)

LSR:	110473096(NUMA1)

SCAN:

103820751(NUMA1)

PMOA:

120513381(NUMA1)

OTC:	121345415(NUMA1)

PRUF:

121354709(NUMA1)

GFR:	102032973(NUMA1)

FAB:	101815825(NUMA1)

OMA:	130259187(NUMA1)

PHI:

102105434

PMAJ:

107203804

CCAE:

111940796

CCW:	104687167(NUMA1)

CBRC:

103613977(NUMA1)

ETL:	114059627(NUMA1)

ZAB:	102065584(NUMA1)

ACHL:

103807560

SVG:	106856596(NUMA1)

MMEA:

130579883(NUMA1)

HRT:	120747594(NUMA1)

FPG:	101917496(NUMA1)

FCH:

102057664

CLV:	102098407(NUMA1)

EGZ:

104133708

NNI:	104011875(NUMA1)

ACUN:

113476008(NUMA1)

TALA:

116963728(NUMA1)

AFOR:

103908492

ACHC:

115353224(NUMA1)

HLE:	104837506(NUMA1)

AGEN:

126048272

GCL:

127028684

SHAB:

115603637(NUMA1)

DPUB:

104302278(NUMA1)

CPEA:

104385319

CVF:	104286753(NUMA1)

RTD:	128904899(NUMA1)

CUCA:

104062205(NUMA1)

AAM:

106483916

AROW:

112961374(NUMA1)

DNE:	112993982(NUMA1)

SCAM:

104143306(NUMA1)

ASN:	102382699(NUMA1)

AMJ:	102569979(NUMA1)

CPOO:

109306857(NUMA1)

GGN:	109302656(NUMA1)

PSS:	102449000(NUMA1)

CMY:	102943307(NUMA1)

CCAY:

125631496(NUMA1)

DCC:	119851111(NUMA1)

CPIC:

101948388(NUMA1)

TST:	117871348(NUMA1)

CABI:

116832137(NUMA1)

MRV:	120396052(NUMA1)

ACS:	100566838(numa1)

ASAO:

132772324(NUMA1)

PVT:	110078122(NUMA1)

SUND:

121925670(NUMA1)

PBI:	103062409(NUMA1)

PMUR:

107299627(NUMA1)

CTIG:

120320229(NUMA1)

TSR:	106541656(NUMA1)

PGUT:

117676439(NUMA1)

APRI:

131199459(NUMA1)

PTEX:

113451117(NUMA1)

NSS:	113430558(NUMA1)

VKO:	123017283(NUMA1)

PMUA:

114595495(NUMA1)

PRAF:

128412443(NUMA1)

ZVI:	118085784(NUMA1)

HCG:	128349306(NUMA1)

GJA:	107113640(NUMA1)

EMC:	129326541(NUMA1)

XLA:	397920(numa1.S) 443581(numa1.L)

XTR:	100145664(numa1)

NPR:	108802510(NUMA1)

RTEM:

120921596(NUMA1)

BBUF:

120996576(NUMA1)

BGAR:

122932357(NUMA1)

MUO:	115468335(NUMA1)

GSH:	117362526(NUMA1)

DRE:	572344(numa1)

SRX:	107706062 107731821

SANH:

107669921 107670062

SGH:	107558821 107560838

CCAR:

109066081

CAUA:

113058882 113081244 113114705(numa1)

CGIB:

127972435 128029063

PTET:

122359028(numa1)

LROH:

127177078(numa1)

OMC:	131520385(numa1)

PPRM:

120470794

RKG:	130101180(numa1)

MAMB:

125248558

CIDE:

127495709

MASI:

127422578 127430120

TROS:

130565127(numa1)

TDW:	130429062(numa1)

MANU:

129438666(numa1)

IPU:

108278230

IFU:	128621687(numa1)

PHYP:

113544592

SMEO:

124394550(numa1)

TFD:	113636450 113637880(numa1) 113650586

TVC:	132858495(numa1)

TRN:	134334705(numa1)

AMEX:

103041455(numa1)

CMAO:

118798766(numa1)

EEE:	113578704(numa1)

TRU:	105417044(numa1)

TFS:	130535546(numa1)

LCO:	104920124(numa1)

TBEN:

117470260(numa1)

CGOB:

115017405(numa1)

PGEO:

117457712(numa1)

GACU:

117534904(numa1)

EMAC:

134880635(numa1)

ELY:	117260263(numa1)

EFO:	125889371(numa1)

PLEP:

121943290(numa1)

SLUC:

116045556(numa1)

ECRA:

117938632(numa1)

ESP:	116687069(numa1)

PFLV:

114552514(numa1)

GAT:	120827129(numa1)

PPUG:

119216688(numa1)

AFB:	129109656(numa1)

CLUM:

117741108(numa1)

PSWI:

130211369(numa1)

MSAM:

119883122(numa1) 119916747

SCHU:

122879433(numa1)

CUD:	121522406(numa1)

ALAT:

119032865(numa1)

MZE:	101482661(numa1)

ONL:	100706456(numa1)

OAU:	116322095(numa1)

OLA:	101165245(numa1)

OML:	112149341(numa1)

CSAI:

133441680(numa1)

XMA:	102230200(numa1)

XCO:	114161837(numa1)

XHE:	116708086(numa1)

PRET:

103474480(numa1)

PFOR:

103146271(numa1)

PLAI:

106958864(numa1)

PMEI:

106927834(numa1)

GAF:	122832958(numa1)

PPRL:

129358903(numa1)

CVG:	107091939(numa1)

CTUL:

119771772(numa1)

GMU:	124883688(numa1)

NFU:	107380462(numa1)

KMR:	108244642(numa1)

ALIM:

106517261(numa1)

NWH:	119411530(numa1)

AOCE:

111570897(numa1)

CSEM:

103378564(numa1)

POV:	109634415(numa1)

SSEN:

122773634(numa1)

HHIP:

117773030(numa1)

HSP:	118106375(numa1)

PPLT:

128440743(numa1)

SMAU:

118298978(numa1)

LCF:

108886612

SDU:	111224044(numa1)

SLAL:

111655301(numa1)

XGL:	120791936(numa1)

HCQ:	109525427(numa1)

SBIA:

133505330(numa1)

PEE:	133405407(numa1)

PTAO:

133482244(numa1)

BPEC:

110174448(numa1)

MALB:

109971601(numa1)

BSPL:

114867548(numa1)

SJO:	128359966(numa1)

SASA:

106613229(numa1)

STRU:

115206589(numa1)

OTW:	112267295(numa1)

OMY:	110503183(numa1)

OGO:	124005130(numa1)

ONE:

115141993

OKI:	109909497(numa1)

OKE:	118394480(numa1)

SALP:

112071325(numa1)

SNH:	120028610(numa1)

ELS:	105024060(numa1)

SFM:	108932226(numa1)

PKI:	111833856(numa1)

AANG:

118210389(numa1)

LOC:	102691667(numa1)

PSPA:

121302868(numa1)

ARUT:

117406012 117972843

LCM:	102358517(NUMA1)

CMK:	103190885(numa1)

RTP:	109936823(numa1)

CPLA:

122550970(numa1)

HOC:	132816579(numa1)

LERI:

129694731(numa1)

BBEL:

SCLV:

PJA:

HAME:

PTRU:

ATEN:

Reference

PMID:20137953

Authors

Radulescu AE, Cleveland DW

Title

NuMA after 30 years: the matrix revisited.

Journal

Trends Cell Biol 20:214-22 (2010)
DOI:10.1016/j.tcb.2010.01.003

Sequence

[hsa:4926]

Reference

PMID:19255246

Authors

Silk AD, Holland AJ, Cleveland DW

Title

Requirements for NuMA in maintenance and establishment of mammalian spindle poles.

Journal

J Cell Biol 184:677-90 (2009)
DOI:10.1083/jcb.200810091

Sequence

[hsa:4926]

All links

Ontology (2)   
   KEGG BRITE (2)   
Disease (1)   
   KEGG DISEASE (1)   
Gene (971)   
   KEGG GENES (378)   
   KEGG MGENES (368)   
   RefGene (220)   
   OC (5)   
Literature (2)   
   PubMed (2)   
All databases (976)   

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