KEGG   Apteryx mantelli mantelli (North Island brown kiwi): 106482245
Entry
106482245         CDS       T04298                                 
Symbol
PIK3CA
Name
(RefSeq) phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha
  KO
K00922  phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
Organism
aam  Apteryx mantelli mantelli (North Island brown kiwi)
Pathway
aam00562  Inositol phosphate metabolism
aam01100  Metabolic pathways
aam04012  ErbB signaling pathway
aam04068  FoxO signaling pathway
aam04070  Phosphatidylinositol signaling system
aam04140  Autophagy - animal
aam04150  mTOR signaling pathway
aam04210  Apoptosis
aam04218  Cellular senescence
aam04370  VEGF signaling pathway
aam04510  Focal adhesion
aam04620  Toll-like receptor signaling pathway
aam04625  C-type lectin receptor signaling pathway
aam04810  Regulation of actin cytoskeleton
aam04910  Insulin signaling pathway
aam04914  Progesterone-mediated oocyte maturation
aam05132  Salmonella infection
aam05164  Influenza A
aam05168  Herpes simplex virus 1 infection
Brite
KEGG Orthology (KO) [BR:aam00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00562 Inositol phosphate metabolism
    106482245 (PIK3CA)
 09130 Environmental Information Processing
  09132 Signal transduction
   04012 ErbB signaling pathway
    106482245 (PIK3CA)
   04370 VEGF signaling pathway
    106482245 (PIK3CA)
   04068 FoxO signaling pathway
    106482245 (PIK3CA)
   04070 Phosphatidylinositol signaling system
    106482245 (PIK3CA)
   04150 mTOR signaling pathway
    106482245 (PIK3CA)
 09140 Cellular Processes
  09141 Transport and catabolism
   04140 Autophagy - animal
    106482245 (PIK3CA)
  09143 Cell growth and death
   04210 Apoptosis
    106482245 (PIK3CA)
   04218 Cellular senescence
    106482245 (PIK3CA)
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    106482245 (PIK3CA)
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    106482245 (PIK3CA)
 09150 Organismal Systems
  09151 Immune system
   04620 Toll-like receptor signaling pathway
    106482245 (PIK3CA)
   04625 C-type lectin receptor signaling pathway
    106482245 (PIK3CA)
  09152 Endocrine system
   04910 Insulin signaling pathway
    106482245 (PIK3CA)
   04914 Progesterone-mediated oocyte maturation
    106482245 (PIK3CA)
 09160 Human Diseases
  09172 Infectious disease: viral
   05164 Influenza A
    106482245 (PIK3CA)
   05168 Herpes simplex virus 1 infection
    106482245 (PIK3CA)
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    106482245 (PIK3CA)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:aam04131]
    106482245 (PIK3CA)
Enzymes [BR:aam01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.1  Phosphotransferases with an alcohol group as acceptor
    2.7.1.153  phosphatidylinositol-4,5-bisphosphate 3-kinase
     106482245 (PIK3CA)
Membrane trafficking [BR:aam04131]
 Endocytosis
  Rab GTPases and associated proteins
   Rab associated proteins
    106482245 (PIK3CA)
SSDB
Motif
Pfam: PI3Ka PI3_PI4_kinase PI3K_C2 PI3K_rbd PI3K_p85B DUF2321 ABC1 Ribosomal_S15
Other DBs
NCBI-GeneID: 106482245
NCBI-ProteinID: XP_013795242
UniProt: A0A8B7I8L7
Position
Un
AA seq 1068 aa
MPPRPSSGELWGIHLMPPRILVECLLPNGMIVTLECLREATLLTIKHELFKEARKYPLYQ
LLQDESSYIFVSVTQEAEREEFFDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDMVKDPEVQDFRRNILNVCKEAVDLRDANAPHSRALYVCPPNVESSPELPKH
IYNKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSSEQLK
LCVLEYQGKYILKVCGCDEYLLEKYPLSQYKYIRSCIMLGRMPNLMLMAKESLYTQLPLD
TFTMPSYSRRISTATPYMNGEATAKSLWSINSALRIRILCATYVNVNIRDIDKIYVRTGI
YHGGEPLCDNVNTQRVPCSNPRWNEWLSYDMYIPDLPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINMFDYTDTLVSGKMALNLWAVPHGLEDLLNPIGVTGSNPNKETPCLELEFDWF
SNPVKFPDMTVIEEHANWTISRELGFNYSYAGLSNRIARDNELRESDKEQLRAICTRDPL
SEITEQEKDFLWSHRHYCVNTPEILPKLLLSVKWNSRDEVAQMYCLVKDWPPIKPEQAME
LLDCNYPDPMVRAFAVRCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNQLVRFLLKKALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLSRQVEAMEKLINLTDILK
QEKKDETQKVQMKFLVEQMRRPDFMDALQGFISPLNPAHQLGNLRLEECRIMSSAKRPLW
LNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLS
IGDCVGLIEVVRSSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNKGEMYDAAIDLFTRS
CAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGAQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIA
YIRKTLALDKTEQEALEYFMKQMNDAHHGGWTTKMDWIFHTIKQHALN
NT seq 3207 nt   +upstreamnt  +downstreamnt
atgcctccacgaccatcatctggtgaactatggggcatccacttgatgccaccaaggatc
cttgtggagtgtcttctaccaaatggaatgatagtgactctagaatgcctccgtgaggcc
acattactaactattaaacatgaactctttaaagaagcaagaaaataccctctctatcag
ctccttcaagatgaatcgtcttacatttttgtaagtgttacccaagaagcagaaagagaa
gaattttttgatgaaacacggagactttgtgacctgcggctctttcagccttttctaaaa
gtcattgaaccagtaggtaacagagaagaaaagattcttaatagagaaataggttttgct
attggcatgcctgtctgtgaatttgacatggttaaggatccagaagtacaagatttcaga
agaaatattctcaatgtttgtaaagaagcagtggatcttcgagatgccaatgcaccacat
agtagagcattatatgtctgtcctccaaatgtagagtcttcgcctgaactacccaaacac
atatacaataaactagataaagggcaaattatagtggtaatatgggtaatagtctcacca
aacaatgataagcagaaatacaccttaaaaatcaatcatgactgtgtgcctgagcaagtt
atcgctgaagcaattaggaagaaaacacgaagtatgttgctgtcatctgaacaactgaaa
ctctgcgtcttggagtaccagggcaagtatattttaaaagtgtgcggctgtgatgagtac
ttgctagaaaaatacccgctgagccagtataagtatataagaagctgtataatgcttggt
cgcatgcctaatttgatgctgatggctaaagagagcctatatacccagctgccactggat
acctttacaatgccatcttattccaggcgcatttctacagctacaccctatatgaatgga
gaagctacagccaaatccctctggtctataaatagtgctctcagaataagaatcctctgt
gcaacctatgtaaatgtgaacatccgagacattgacaagatctatgttcgaacaggtatc
taccatggaggggagcctttgtgtgacaatgtgaatactcagagagtaccttgttctaat
cccaggtggaatgaatggctatcgtatgacatgtacattcctgatcttccacgtgctgct
cgactctgcctttcaatctgttctgttaaaggccggaagggtgctaaagaggaacactgt
ccattggcttggggaaatataaacatgtttgattacacagacactcttgtatctgggaaa
atggctttgaatctttgggcagtacctcatgggctggaggatttgttgaatcctattggt
gttactggatcaaatccaaataaggaaactccatgtttagagctggaatttgattggttt
agcaatcctgtaaagtttccagatatgacagtgattgaagaacacgccaattggactata
tcacgtgaactagggtttaactacagctatgcggggctgagtaacagaatagctagagat
aatgaattaagagaaagcgacaaggagcaactgcgagctatatgtacccgagatcctctg
tctgaaatcactgagcaagagaaggactttctttggagccacagacactattgtgtaaat
accccagaaattctacccaaattgcttttatctgttaaatggaattccagagatgaagta
gcccagatgtactgtttggtaaaagactggcctccaatcaagccagagcaagcaatggag
cttttggactgtaattatccagatccaatggtgcgagcctttgcggttcggtgtctagag
aagtacttgacagatgacaaactttcacaatacttaatccagctagtacaggttctgaaa
tatgaacagtatttagataatcaacttgtgagatttttactcaagaaggcactgaccaat
caaaggataggacacttcttcttttggcatttaaagtctgaaatgcacaataaaactgta
agtcagaggtttggtttacttctggagtcctattgtcgagcgtgtggaatgtacctaaag
catctgagcaggcaggtggaggctatggagaagttgattaacctcacagatattctcaag
caggaaaaaaaagatgagacccagaaggtgcaaatgaagtttcttgttgaacaaatgagg
cgaccagattttatggatgctttacaaggctttatctctcctcttaatcctgctcatcaa
ctgggaaatcttcggcttgaggagtgcaggataatgtcatctgcaaaaaggcccctgtgg
ttgaactgggaaaacccagatattatgtctgaattgttatttcagaacaacgagataatc
tttaaaaatggagatgacttacgtcaggacatgctgacacttcagataattagaattatg
gaaaacatctggcaaaatcagggtcttgatcttcggatgttgccttatggttgtttatct
attggtgactgcgtgggacttattgaggtagtgaggagctctcatacaatcatgcagatt
cagtgtaaaggaggcttaaagggtgcgttgcagttcaacagccatacattacatcagtgg
ctcaaggacaagaacaaaggagaaatgtatgatgcagctattgacttgtttacacgttct
tgtgccggctactgtgttgctacctttatactgggcattggtgatcgccacaatagtaac
atcatggtgaaagatgatggacaactgtttcacattgattttgggcacttccttgatcac
aagaagaaaaaatttggttataaaagagaacgtgtgccatttgtcttaacacaagacttt
ttaatagtgattagtaaaggagcccaagaatgtaccaaaacaagggagtttgaaaggttt
caggagatgtgttataaggcttatctagcaattcggcaacatgccaatctcttcataaat
ctattctccatgatgcttggctcaggaatgccagaactgcagtcttttgatgatattgca
tacattcgaaagactcttgcattggacaaaaccgagcaggaagctcttgagtacttcatg
aagcaaatgaatgatgctcaccatggtggctggacaacaaaaatggactggatcttccac
acaataaagcaacatgccttgaactga

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Ontology (3)   
   KEGG BRITE (3)   
Pathway (19)   
   KEGG PATHWAY (19)   
Chemical substance (4)   
   KEGG COMPOUND (4)   
Chemical reaction (2)   
   KEGG ENZYME (1)   
   KEGG REACTION (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (18)   
   KEGG ORTHOLOGY (1)   
   RefGene (14)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   OC (1)   
Protein sequence (2)   
   UniProt (1)   
   RefSeq(pep) (1)   
DNA sequence (1)   
   RefSeq(nuc) (1)   
Protein domain (8)   
   Pfam (8)   
All databases (58)   

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