KEGG   Apteryx mantelli mantelli (North Island brown kiwi): 106499764
Entry
106499764         CDS       T04298                                 
Symbol
DPYD
Name
(RefSeq) dihydropyrimidine dehydrogenase
  KO
K00207  dihydropyrimidine dehydrogenase (NADP+) [EC:1.3.1.2]
Organism
aam  Apteryx mantelli mantelli (North Island brown kiwi)
Pathway
aam00240  Pyrimidine metabolism
aam00410  beta-Alanine metabolism
aam00770  Pantothenate and CoA biosynthesis
aam00983  Drug metabolism - other enzymes
aam01100  Metabolic pathways
Module
aam_M00046  Pyrimidine degradation, uracil => beta-alanine, thymine => 3-aminoisobutanoate
Brite
KEGG Orthology (KO) [BR:aam00001]
 09100 Metabolism
  09104 Nucleotide metabolism
   00240 Pyrimidine metabolism
    106499764 (DPYD)
  09106 Metabolism of other amino acids
   00410 beta-Alanine metabolism
    106499764 (DPYD)
  09108 Metabolism of cofactors and vitamins
   00770 Pantothenate and CoA biosynthesis
    106499764 (DPYD)
  09111 Xenobiotics biodegradation and metabolism
   00983 Drug metabolism - other enzymes
    106499764 (DPYD)
Enzymes [BR:aam01000]
 1. Oxidoreductases
  1.3  Acting on the CH-CH group of donors
   1.3.1  With NAD+ or NADP+ as acceptor
    1.3.1.2  dihydropyrimidine dehydrogenase (NADP+)
     106499764 (DPYD)
SSDB
Motif
Pfam: DHO_dh Fer4_20 Fer4_21 Pyr_redox_2 NAD_binding_8 Fer4_7 Pyr_redox_3 Dus Fer4_10 Fer4_6 Pyr_redox Fer4_9 Fer4_2 Fer4 FAD_oxidored MurD-like_N
Other DBs
NCBI-GeneID: 106499764
NCBI-ProteinID: XP_013816775
UniProt: A0A8B7K0S4
Position
Un
AA seq 1027 aa
MPEQVLAFQIKICIKNILALNPRTQTHATLHSTAAKKQVKKQWKRNSDKSCSNCEKLENN
FDDIKHTTLSERGALHEAVRCLKCADAPCQKSCPTNLDIKSFITSIANKNYYGAAKMILS
DNPLGLTCGMVCPTSDLCVGGCNLYATEEGPINIGGLQQFATEVFKAMNIPQIRNPSLPP
LEEMPEAYHVKIALLGAGPASISCASFLARLGYSNITIYEKQEYVGGLSTSEIPQFRLPY
DAVNFEAELMKDLGVKVVFSKGLAIDGMTLRTLKEDGYKAVFIGIGLPEPNRDSIFQGLR
MDQGFYTSKDFLPLVAMASKPGMCACHSPLPSIHGTVIVLGAGDTAFDCATSALRCGAHR
VFVVFRKGFTNIRAVPEEVELAKEEKCEFLPFLSPQKVVLRGEQIVAMEFVRTEQDKNGN
WKEDVDQVVRLKADVVISAFGSVLSDTKVREAMTPVKFNRWGLPEVDPETMQTSEPWVFA
GGDIGGLANTTVESVNDGKQASWYMHRYIQSLYGAAVSTTPELPLFYTPIDLVDISVEMA
GLKFPNPFGLASATPTTSSSMIRRAFEAGWGFSVTKTFSLDKDIVTNVSPRIVRGVTSGP
IYGPGQGSFLNIELISEKTAAYWCRSIAELKADFPNHILIASIMSSYSKDDWTELSKMAE
VAGADALELNLSCPHGMGERGMGLACGQDPELVRNICRWVRQAVQIPFFAKLTPNVTDIV
KIAVAAQEGGADGVTATNTVSGLMGLNADSTPWPAVGGGQRTTYGGMSGNAIRPIALRAV
SAIARALPGFPILATGGIDSAESGLQFLHSGASVLQVCSAIQNQDFTVIDDYCTGLRALL
YLKSIEELKDWNGQSPATIQHQKGKPVPKIADLMGKKLPSFGPYLEQRKKIIAENKIKLK
KQSTAALLPRKKHFVPKKPIPAIKDVIGKALQYIGTYGELSNTEQVVALIDEEMCINCGK
CYMTCNDSGYQAIRFDPKTHLPRVTDGCTGCTLCLSVCPVIDCIRMVSRTTPYEPKRGLP
LAVNPAC
NT seq 3084 nt   +upstreamnt  +downstreamnt
atgccagagcaagtattggcttttcagatcaagatatgtataaagaacattctggcttta
aatccccgaacgcagactcatgcaaccctccattcaactgcagcaaagaaacaagtcaag
aagcaatggaaaaggaattctgataaaagctgttcaaactgtgagaaactagaaaataat
tttgatgacatcaagcacacgactctcagtgagcgcggagcacttcacgaagcagtgaga
tgcttaaagtgtgcagatgccccgtgtcagaagagttgcccaactaatctggacatcaag
tcatttatcacaagtattgcaaacaagaactattatggagctgccaaaatgattctttct
gacaatccgcttgggctcacatgtggaatggtgtgtccaacttctgatctttgtgttggt
ggctgcaatttgtatgccactgaggagggaccaattaatattggtggattgcagcagttt
gctactgaggtgttcaaagctatgaatattcctcagattagaaacccttcattacctcct
ctagaagagatgcctgaagcctatcatgtgaagatagctctccttggcgcaggacctgca
agtataagttgtgcttcttttctggctcgattgggctactcaaatatcaccatatatgaa
aagcaggagtatgttggtggcttaagtacatctgaaatcccccagttccgattgccatat
gatgcagtgaattttgaagctgagcttatgaaggatcttggagtgaaggttgtttttagt
aaaggcctcgcaatagatggaatgacgctccgtaccttgaaagaagatggttacaaagca
gtctttattggaataggtttgccagaaccaaacagagacagtatattccaaggactgaga
atggatcaaggattctacacatctaaagacttcctacctttggtagcaatggcaagtaaa
ccagggatgtgtgcctgtcactccccattgccatcaattcatggaactgtgattgtactt
ggggcaggagacacggcttttgactgtgcaacatctgccttacgctgtggagctcaccgt
gtatttgtggtattcagaaagggattcactaatatcagagctgtcccagaagaggtggaa
cttgcaaaagaagaaaagtgtgaatttctgcctttcctctcccctcaaaaagtggtactt
agaggtgaacaaattgttgctatggagtttgttcgaactgaacaagacaaaaatggaaat
tggaaagaagatgtggatcaggttgtccgtctgaaagctgatgtggtgatcagtgccttt
ggttcagttttaagtgacactaaagtcagagaagccatgacacctgtcaagtttaataga
tggggtctccctgaagtagatccagaaactatgcaaacaagtgaaccctgggtgtttgca
ggtggtgacattggtggtcttgctaacactactgtggaatcagtaaatgatggaaaacaa
gcttcctggtacatgcacagatacatacagtctttatatggtgctgctgtttccactact
ccagaactaccgctcttctatacccctatcgatttagtagacatcagtgtagaaatggct
ggactgaagtttccaaatccttttggtcttgccagtgcaactcccactactagttcttca
atgattcgaagagcttttgaagctggatggggcttctctgtcactaaaacattctccctg
gataaggatattgtgaccaatgtttctccaaggattgtgcgtggagttacttcaggtccg
atatatggcccaggtcaaggctcttttctaaacattgaactgatcagcgagaaaacagca
gcctattggtgtagaagtattgctgaattaaaggctgactttccaaaccatattctaatt
gccagtatcatgagcagctacagcaaggatgactggactgaactttcaaaaatggctgag
gttgctggtgcagatgcactggagttaaatttgtcatgtcctcatggtatgggagagaga
ggcatgggcctggcctgtgggcaggatccagagctggtacggaacatctgtcgctgggtt
agacaagctgttcagattcctttctttgccaagctgaccccaaatgtcactgatattgtg
aaaattgcagtggctgcacaggaaggtggtgcagatggtgttacagccaccaacactgtg
tcgggactgatgggactgaacgcagacagcacaccttggccagcagttggtggaggacag
aggaccacatatggtggcatgtcaggaaatgccattcggcccatagccctccgtgcagtg
tctgctatagcccgtgctcttccagggtttcccatcttagcaactggaggaattgattct
gctgaaagtgggctccagtttctgcacagtggcgcttctgttttacaggtgtgcagtgca
atccagaatcaagatttcactgttattgatgactactgcactggactgagagccctcctt
tacttgaaaagtattgaggaacttaaagactggaatggacagagtcctgctaccatacag
catcagaaaggaaaaccagtacctaaaattgctgatctgatgggaaagaaactacctagt
tttgggccttacctggaacaacgcaaaaagataatagctgagaacaaaattaaactgaag
aaacagagcacagctgctttgctccccaggaaaaaacatttcgttccaaagaagcccatt
ccagcaatcaaggatgtaattggaaaagcactgcagtatattggaacatatggcgagctc
agcaacacagagcaagttgtggctctgattgacgaggaaatgtgtatcaactgtggcaaa
tgttacatgacctgtaatgattctggctaccaggctatacggtttgatcccaaaacccac
ctgcccagggttactgacggttgtaccggctgcaccctgtgtctcagtgtctgccctgtt
attgactgcatccgcatggtttccaggacaaccccatacgaaccaaagcgagggctgccc
ttagcggtgaacccagcgtgctga

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Ontology (2)   
   KEGG BRITE (2)   
Pathway (6)   
   KEGG PATHWAY (5)   
   KEGG MODULE (1)   
Chemical substance (9)   
   KEGG COMPOUND (9)   
Chemical reaction (4)   
   KEGG ENZYME (1)   
   KEGG REACTION (3)   
Genome (1)   
   KEGG GENOME (1)   
Gene (17)   
   KEGG ORTHOLOGY (1)   
   RefGene (13)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   OC (1)   
Protein sequence (2)   
   UniProt (1)   
   RefSeq(pep) (1)   
DNA sequence (1)   
   RefSeq(nuc) (1)   
Protein domain (16)   
   Pfam (16)   
All databases (58)   

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