KEGG   Acinonyx jubatus (cheetah): 106966295
Entry
106966295         CDS       T04657                                 
Name
(RefSeq) beta-secretase 1
  KO
K04521  beta-site APP-cleaving enzyme 1 (memapsin 2) [EC:3.4.23.46]
Organism
aju  Acinonyx jubatus (cheetah)
Pathway
aju05010  Alzheimer disease
Brite
KEGG Orthology (KO) [BR:aju00001]
 09160 Human Diseases
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    106966295
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01002 Peptidases and inhibitors [BR:aju01002]
    106966295
Enzymes [BR:aju01000]
 3. Hydrolases
  3.4  Acting on peptide bonds (peptidases)
   3.4.23  Aspartic endopeptidases
    3.4.23.46  memapsin 2
     106966295
Peptidases and inhibitors [BR:aju01002]
 Aspartic peptidases
  Family A1: pepsin family
   106966295
SSDB
Motif
Pfam: Asp TAXi_C TAXi_N PE-PGRS_C
Other DBs
NCBI-GeneID: 106966295
NCBI-ProteinID: XP_014917895
UniProt: A0A6I9ZGM1
Position
D1:98341971..98364127
AA seq 501 aa
MAQTLPWLLLWMSSGMLPAHCTQPGIRLPLRSGLGGAPLGLRLPRETDEEQEEPGRRGSF
VEMVDNLRGKSGQGYYVEMTVGSPPQTLNILVDTGSSNFAVGASPHPFLHRYYQRQLSST
YRDLRKGVYVPYTQGKWEGELGTDLVSIPHGPNVTVRANIAAITESDKFFINGSNWEGIL
GLAYAEIARPDDSLEPFFDSLVKQTHVPNLFSLQLCGAGFPLNQSEVLASVGGSMIIGGI
DHSLYTGSLWYTPIRREWYYEVIIVRVEINGQDLKMDCKEYNYDKSIVDSGTTNLRLPKK
VFEAAVKSIKAASSTEKFPDGFWLGEQLVCWQAGTTPWNIFPVISLYLMGEVTNQSFRIT
ILPQQYLRPVEDVATSQDDCYKFAISQSSTGTVMGAVIMEGFYVVFDRARKRIGFAVSAC
HVHDEFRTAAVEGPFVTPDMEDCGYNIPQTDESTLMTIAYVMAAICALFMLPLCLMVCQW
RCLRCLRHQHDDFADDISLLK
NT seq 1506 nt   +upstreamnt  +downstreamnt
atggcccaaacactgccctggctcctgctgtggatgagctcgggaatgctgcctgcccac
tgcacccagcctggcatccggctgcccctgcgaagcgggctagggggggcccccctgggg
ctgcggctgccccgggagaccgacgaggaacaagaggagccgggccggaggggcagcttt
gtggagatggtggacaacctgaggggcaagtccggtcagggctactacgtggagatgacc
gtgggcagccccccacagacgctcaacatcctggtggacacgggcagcagtaactttgca
gtgggggcttccccccaccctttcctgcaccgctactaccagaggcagctgtccagcacg
taccgggacctccggaagggtgtgtatgtgccctacacccagggcaagtgggagggagag
ctgggcaccgacctggtgagcatcccccacggccccaacgtcactgtgcgtgccaacatc
gctgccatcactgaatcagacaagttcttcatcaatggctccaactgggaaggcatcctg
gggctggcctatgctgaaattgccaggcccgatgactccctggagccgttctttgactcc
ctggtaaagcagacccacgttcccaacctcttctccctgcagctctgcggtgccggcttt
cccctcaaccagtcagaagtgctggcctcagttggagggagcatgatcattgggggcatc
gaccactcactgtacacgggcagcctctggtacacacccatccggcgggagtggtactac
gaggtgatcattgtgcgggtggagatcaacgggcaggatctgaagatggactgcaaggag
tacaactacgacaagagcatcgtggacagtggcaccaccaaccttcgtttgcccaagaag
gtgtttgaagccgccgttaaatccatcaaggcagcctcctcgacggagaagtttccggac
gggttttggctgggggaacagctggtgtgctggcaagcaggcaccaccccttggaacatt
ttcccagtcatctccctctacctaatgggtgaggtcaccaatcagtccttccgcatcacc
atccttccacagcaatacctgcggccagtggaagacgtggccacgtcccaagatgactgc
tacaagttcgccatctcacagtcctccacgggcacggttatgggagctgtgatcatggag
ggcttctacgtggtctttgatcgggcccggaaacgaattggctttgctgtcagtgcttgt
cacgtgcatgatgagttcaggacagcagcagtggaaggccctttcgtcaccccagacatg
gaagactgtggctacaacatcccacagacagatgaatcaaccctcatgaccatagcctac
gtcatggctgccatctgcgccctcttcatgctgccactgtgcctcatggtgtgccagtgg
cgctgcctccgctgcctgcgccatcaacatgatgactttgcggacgacatctccctgttg
aagtga

  All links  
Ontology (3)   
   KEGG BRITE (3)   
Pathway (1)   
   KEGG PATHWAY (1)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (4)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   OC (1)   
Protein sequence (2)   
   UniProt (1)   
   RefSeq(pep) (1)   
DNA sequence (1)   
   RefSeq(nuc) (1)   
Protein domain (4)   
   Pfam (4)   
All databases (17)   

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