KEGG   Alligator mississippiensis (American alligator): 102575202
Entry
102575202         CDS       T03087                                 
Symbol
GCLC
Name
(RefSeq) glutamate-cysteine ligase catalytic subunit
  KO
K11204  glutamate--cysteine ligase catalytic subunit [EC:6.3.2.2]
Organism
amj  Alligator mississippiensis (American alligator)
Pathway
amj00270  Cysteine and methionine metabolism
amj00480  Glutathione metabolism
amj01100  Metabolic pathways
amj01240  Biosynthesis of cofactors
amj04216  Ferroptosis
Module
amj_M00118  Glutathione biosynthesis, glutamate => glutathione
Brite
KEGG Orthology (KO) [BR:amj00001]
 09100 Metabolism
  09105 Amino acid metabolism
   00270 Cysteine and methionine metabolism
    102575202 (GCLC)
  09106 Metabolism of other amino acids
   00480 Glutathione metabolism
    102575202 (GCLC)
 09140 Cellular Processes
  09143 Cell growth and death
   04216 Ferroptosis
    102575202 (GCLC)
Enzymes [BR:amj01000]
 6. Ligases
  6.3  Forming carbon-nitrogen bonds
   6.3.2  Acid-D-amino-acid ligases (peptide synthases)
    6.3.2.2  glutamate---cysteine ligase
     102575202 (GCLC)
SSDB
Motif
Pfam: GCS GCS2
Other DBs
NCBI-GeneID: 102575202
NCBI-ProteinID: XP_014460840
Position
Un
AA seq 602 aa
MELGTGCLIKGDCPPNVEYMLVAFDHENKKVRLLLSGEDVLHTLQEKGERINPNHPTLWR
PEYGRYMIEGTPGQPYGGTMSEFNTVQDNMRKRRLEAASVLKENEAVCTVTSFPRLGCPG
FTLPEHEPTPVEGGVSKSLFFPDEAINKHPRFSTLTRNIRHRRGEKVVINVPIFKDKNTP
SPFTEIFPNDDGEAAKAAKPDHIYMDAMGFGMGNCCLQVTFQACSISEARYLYDQLATIC
PIVMALSAASPFYRGCVSDIDCRWGVISASVDDRTREERGLEPLKNNRYRISKSRYDSID
SYLSECGEKYNDIDLTIDKEIYEHLVKEGIDHLLAQHIAHLFIRDPLTLFEEKIHLDDAN
ESDHFENIQSTNWQTMRFKPPPPNSDIGWRVEFRPMEVQLTDFENSAYVVFVVLLTRVIL
SYKLDFLIPLSKVDENMKVAQKRDAVRQGMFYFRKDICKGGNAVVDGCGPAQNGTDTDAE
EYILMSIDTIINGKEGVFPGLIPVLNSYLENMEVDVDTRCTILNYLKLIKKRASGELMTV
ARWMREFVANYPDYKQDSVITDEINYSLIWKCNQIAQGRTECPELLGAVFNKKHSGIKSG
SS
NT seq 1809 nt   +upstreamnt  +downstreamnt
atggaactgggaacgggctgcttaattaaaggagactgccctcctaatgtggaatatatg
ttggtagcttttgatcatgaaaataagaaagtgcgtttgttgctaagtggagaagacgtt
cttcatactctgcaagagaagggggaaaggattaaccccaaccacccaacactctggcga
ccagagtatggaaggtatatgattgaagggacacctgggcagccatatggaggaacaatg
tctgaattcaacactgtacaagacaacatgaggaaacgacgactggaagctgcttctgta
ctgaaagaaaatgaggctgtttgcactgtaacatcctttccaaggctagggtgtccagga
ttcaccctaccagaacatgagccaacaccagtagaaggaggagtatcaaagtctctgttc
tttccagatgaagccatcaacaaacatcctagatttagtacactgacaagaaacattcga
caccggagaggagagaaagtagtgataaatgtaccaatatttaaagacaagaacacacca
tcaccattcactgaaatatttcccaatgatgatggcgaagcagctaaagcagctaaacca
gaccatatatacatggatgccatgggttttggaatgggcaactgctgccttcaggtaaca
ttccaggcttgcagcatttctgaagcaagatatctttatgatcagctagctacaatctgt
cccattgtgatggcattaagtgctgcatctccgttctacagaggctgtgtgtcagatatt
gattgtcgctggggagtaatctctgcatctgtagatgatcgaacacgagaggagagaggg
ttggagccactgaagaacaatcgttatagaatcagtaaatccagatacgattccatagac
agttacctttctgaatgcggtgaaaaatacaatgacattgatttgaccattgacaaagaa
atctatgaacacctagtaaaagaaggaattgatcatcttttggcacagcacattgctcac
ttgtttattcgagacccattgactttgtttgaagagaaaatacatctggatgatgcaaat
gagtctgaccattttgagaatattcagtccacaaattggcagacaatgagatttaaacca
cctcctccgaattcagatattggctggagagtagaattcaggcccatggaggttcagtta
acagactttgaaaattctgcatatgttgtgtttgtagtattgctaaccagagtgattctg
tcatataaactggattttctcatccctttatcgaaggttgatgaaaatatgaaggtagcc
cagaaacgagatgctgtccgacaggggatgttttatttcagaaaagatatttgtaaaggt
ggaaatgctgttgtggatggatgtggcccagctcagaatgggacagacacagatgcagaa
gagtacatcttaatgagcatagatactatcatcaatgggaaggaaggggtctttcctggt
ttaatccctgttctgaactcttaccttgaaaacatggaagtggatgtggacacaagatgc
accattctaaactacctgaagttaataaagaagagagcctctggagagttaatgacagtt
gcccgatggatgagggagtttgttgctaattatcctgactacaagcaagatagtgtgata
actgatgaaattaattatagcctgatttggaagtgcaaccagatcgcacaaggacggaca
gagtgccctgaattacttggagcagtatttaacaaaaaacacagtggaattaaaagtggt
tcttcttaa

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Ontology (2)   
   KEGG BRITE (2)   
Pathway (6)   
   KEGG PATHWAY (5)   
   KEGG MODULE (1)   
Chemical substance (8)   
   KEGG COMPOUND (8)   
Chemical reaction (3)   
   KEGG ENZYME (1)   
   KEGG REACTION (2)   
Genome (1)   
   KEGG GENOME (1)   
Gene (4)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   OC (1)   
Protein sequence (8)   
   RefSeq(pep) (8)   
DNA sequence (8)   
   RefSeq(nuc) (8)   
Protein domain (2)   
   Pfam (2)   
All databases (42)   

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